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PubMed:20053626 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-135 Sentence denotes Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus.
TextSentencer_T2 136-272 Sentence denotes Protein O-mannosyltransferases (PMTs) initiate O-mannosylation of secretory proteins, which are of fundamental importance in eukaryotes.
TextSentencer_T3 273-396 Sentence denotes The human fungal pathogen Aspergillus fumigatus possesses three genes encoding for PMTs, namely, Afpmt1, Afpmt2 and Afpmt4.
TextSentencer_T4 397-605 Sentence denotes We have previously shown that lack of AfPmt1 leads to a temperature-sensitive phenotype featured with severe defects in hyphal growth, conidiation, cell wall integrity and morphology at elevated temperatures.
TextSentencer_T5 606-752 Sentence denotes In this study, a conditional mutant P2 was constructed by replacing the native promoter of the Afpmt2 with the Aspergillus nidulans alcA promoter.
TextSentencer_T6 753-953 Sentence denotes Reduced expression of the Afpmt2 gene led to a lagged germination, retarded hyphal growth, reduced conidiation and defect in cell wall integrity; however, no temperature-sensitive growth was observed.
TextSentencer_T7 954-1063 Sentence denotes Further analysis revealed that reduced expression of the Afpmt2 caused a failure of the actin re-arrangement.
TextSentencer_T8 1064-1192 Sentence denotes Our results suggest that Afpmt2 gene was required for growth and played a role distinct from that of the Afpmt1 in A. fumigatus.
T1 0-135 Sentence denotes Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus.
T2 136-272 Sentence denotes Protein O-mannosyltransferases (PMTs) initiate O-mannosylation of secretory proteins, which are of fundamental importance in eukaryotes.
T3 273-396 Sentence denotes The human fungal pathogen Aspergillus fumigatus possesses three genes encoding for PMTs, namely, Afpmt1, Afpmt2 and Afpmt4.
T4 397-605 Sentence denotes We have previously shown that lack of AfPmt1 leads to a temperature-sensitive phenotype featured with severe defects in hyphal growth, conidiation, cell wall integrity and morphology at elevated temperatures.
T5 606-752 Sentence denotes In this study, a conditional mutant P2 was constructed by replacing the native promoter of the Afpmt2 with the Aspergillus nidulans alcA promoter.
T6 753-953 Sentence denotes Reduced expression of the Afpmt2 gene led to a lagged germination, retarded hyphal growth, reduced conidiation and defect in cell wall integrity; however, no temperature-sensitive growth was observed.
T7 954-1063 Sentence denotes Further analysis revealed that reduced expression of the Afpmt2 caused a failure of the actin re-arrangement.
T8 1064-1192 Sentence denotes Our results suggest that Afpmt2 gene was required for growth and played a role distinct from that of the Afpmt1 in A. fumigatus.
T1 0-135 Sentence denotes Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus.
T2 136-272 Sentence denotes Protein O-mannosyltransferases (PMTs) initiate O-mannosylation of secretory proteins, which are of fundamental importance in eukaryotes.
T3 273-396 Sentence denotes The human fungal pathogen Aspergillus fumigatus possesses three genes encoding for PMTs, namely, Afpmt1, Afpmt2 and Afpmt4.
T4 397-605 Sentence denotes We have previously shown that lack of AfPmt1 leads to a temperature-sensitive phenotype featured with severe defects in hyphal growth, conidiation, cell wall integrity and morphology at elevated temperatures.
T5 606-752 Sentence denotes In this study, a conditional mutant P2 was constructed by replacing the native promoter of the Afpmt2 with the Aspergillus nidulans alcA promoter.
T6 753-953 Sentence denotes Reduced expression of the Afpmt2 gene led to a lagged germination, retarded hyphal growth, reduced conidiation and defect in cell wall integrity; however, no temperature-sensitive growth was observed.
T7 954-1063 Sentence denotes Further analysis revealed that reduced expression of the Afpmt2 caused a failure of the actin re-arrangement.
T8 1064-1192 Sentence denotes Our results suggest that Afpmt2 gene was required for growth and played a role distinct from that of the Afpmt1 in A. fumigatus.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 136-143 FMAID:67257 denotes Protein
_T2 136-143 FMAID:165447 denotes Protein
_T3 212-220 FMAID:67257 denotes proteins
_T4 212-220 FMAID:165447 denotes proteins
_T5 337-342 FMAID:198663 denotes genes
_T6 786-790 FMAID:198663 denotes gene
_T7 875-882 FMAID:84785 denotes in cell
_T8 875-882 FMAID:199054 denotes in cell
_T9 1042-1047 FMAID:67843 denotes actin
_T10 1042-1047 FMAID:90069 denotes actin
_T11 1048-1050 FMAID:178331 denotes re
_T12 1096-1100 FMAID:198663 denotes gene

uniprot-human

Id Subject Object Predicate Lexical cue
T1 642-644 http://www.uniprot.org/uniprot/P04554 denotes P2

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 642-644 http://www.uniprot.org/uniprot/Q9R0C0 denotes P2
T2 800-806 http://www.uniprot.org/uniprot/Q9ESF4 denotes lagged
T3 800-806 http://www.uniprot.org/uniprot/P54227 denotes lagged

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 113-124 http://purl.bioontology.org/ontology/NCBITAXON/40382 denotes Aspergillus
T2 113-124 http://purl.bioontology.org/ontology/NCBITAXON/454240 denotes Aspergillus
T3 113-124 http://purl.bioontology.org/ontology/NCBITAXON/41750 denotes Aspergillus
T4 113-134 http://purl.bioontology.org/ontology/NCBITAXON/340412 denotes Aspergillus fumigatus
T5 113-134 http://purl.bioontology.org/ontology/NCBITAXON/340414 denotes Aspergillus fumigatus
T6 113-134 http://purl.bioontology.org/ontology/NCBITAXON/607716 denotes Aspergillus fumigatus
T7 113-134 http://purl.bioontology.org/ontology/NCBITAXON/286432 denotes Aspergillus fumigatus
T8 261-271 http://purl.bioontology.org/ontology/NCBITAXON/2759 denotes eukaryotes
T9 299-310 http://purl.bioontology.org/ontology/NCBITAXON/454240 denotes Aspergillus
T10 299-310 http://purl.bioontology.org/ontology/NCBITAXON/41750 denotes Aspergillus
T11 299-310 http://purl.bioontology.org/ontology/NCBITAXON/40382 denotes Aspergillus
T12 299-320 http://purl.bioontology.org/ontology/NCBITAXON/340412 denotes Aspergillus fumigatus
T13 299-320 http://purl.bioontology.org/ontology/NCBITAXON/286432 denotes Aspergillus fumigatus
T14 299-320 http://purl.bioontology.org/ontology/NCBITAXON/607716 denotes Aspergillus fumigatus
T15 299-320 http://purl.bioontology.org/ontology/NCBITAXON/340414 denotes Aspergillus fumigatus
T16 717-728 http://purl.bioontology.org/ontology/NCBITAXON/41750 denotes Aspergillus
T17 717-728 http://purl.bioontology.org/ontology/NCBITAXON/454240 denotes Aspergillus
T18 717-728 http://purl.bioontology.org/ontology/NCBITAXON/40382 denotes Aspergillus
T19 717-737 http://purl.bioontology.org/ontology/NCBITAXON/162425 denotes Aspergillus nidulans
T20 738-742 http://purl.bioontology.org/ontology/NCBITAXON/28688 denotes alcA
T21 800-806 http://purl.bioontology.org/ontology/NCBITAXON/254545 denotes lagged

GO-BP

Id Subject Object Predicate Lexical cue
T1 136-166 http://purl.obolibrary.org/obo/GO_0004169 denotes Protein O-mannosyltransferases
T2 185-198 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylation
T3 465-474 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitive
T4 923-932 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitive
T5 517-530 http://purl.obolibrary.org/obo/GO_0030448 denotes hyphal growth
T6 829-842 http://purl.obolibrary.org/obo/GO_0030448 denotes hyphal growth
T7 524-530 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T8 836-842 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T9 933-939 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T10 1118-1124 http://purl.obolibrary.org/obo/GO_0040007 denotes growth

GO-CC

Id Subject Object Predicate Lexical cue
T1 78-82 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 545-549 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 878-882 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 78-87 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T5 545-554 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T6 878-887 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall

Allie

Id Subject Object Predicate Lexical cue
SS1_20053626_1_0 136-166 expanded denotes Protein O-mannosyltransferases
SS2_20053626_1_0 168-172 abbr denotes PMTs
AE1_20053626_1_0 SS1_20053626_1_0 SS2_20053626_1_0 abbreviatedTo Protein O-mannosyltransferases,PMTs

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 113-134 OrganismTaxon denotes Aspergillus fumigatus 746128
T2 261-271 OrganismTaxon denotes eukaryotes 2759
T3 277-282 OrganismTaxon denotes human 9606
T4 299-320 OrganismTaxon denotes Aspergillus fumigatus 746128
T5 717-737 OrganismTaxon denotes Aspergillus nidulans 162425

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 83-87 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060
T2 550-554 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060
T3 883-887 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060