PubMed:20046642
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-171 | Sentence | denotes | Metallothionein induction reduces caspase-3 activity and TNFalpha levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats. |
| T2 | 172-231 | Sentence | denotes | Hippocampal integrity is essential for cognitive functions. |
| T3 | 232-348 | Sentence | denotes | On the other hand, induction of metallothionein (MT) by ZnSO(4) and its role in neuroprotection has been documented. |
| T4 | 349-482 | Sentence | denotes | The present study aimed to explore the effect of MT induction on carmustine (BCNU)-induced hippocampal cognitive dysfunction in rats. |
| T5 | 483-571 | Sentence | denotes | A total of 60 male Wistar albino rats were randomly divided into four groups (15/group): |
| T6 | 572-684 | Sentence | denotes | The control group injected with single doses of normal saline (i.c.v) followed 24 h later by BCNU solvent (i.v). |
| T7 | 685-810 | Sentence | denotes | The second group administered ZnSO(4) (0.1 micromol/10 microl normal saline, i.c.v, once) then BCNU solvent (i.v) after 24 h. |
| T8 | 811-907 | Sentence | denotes | Third group received BCNU (20 mg/kg, i.v, once) 24 h after injection with normal saline (i.c.v). |
| T9 | 908-1044 | Sentence | denotes | Fourth group received a single dose of ZnSO(4) (0.1 micromol/10 microl normal saline, i.c.v) then BCNU (20 mg/kg, i.v, once) after 24 h. |
| T10 | 1045-1321 | Sentence | denotes | The obtained data revealed that BCNU administration resulted in deterioration of learning and short-term memory (STM), as measured by using radial arm water maze, accompanied with decreased hippocampal glutathione reductase (GR) activity and reduced glutathione (GSH) content. |
| T11 | 1322-1524 | Sentence | denotes | Also, BCNU administration increased serum tumor necrosis factor-alpha (TNFalpha), hippocampal MT and malondialdehyde (MDA) contents as well as caspase-3 activity in addition to histological alterations. |
| T12 | 1525-1719 | Sentence | denotes | ZnSO(4) pretreatment counteracted BCNU-induced inhibition of GR and depletion of GSH and resulted in significant reduction in the levels of MDA and TNFalpha as well as the activity of caspase-3. |
| T13 | 1720-1849 | Sentence | denotes | The histological features were improved in hippocampus of rats treated with ZnSO(4) + BCNU compared to only BCNU-treated animals. |
| T14 | 1850-2086 | Sentence | denotes | In conclusion, MT induction halts BCNU-induced hippocampal toxicity as it prevented GR inhibition and GSH depletion and counteracted the increased levels of TNFalpha, MDA and caspase-3 activity with subsequent preservation of cognition. |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 166-170 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T4 | 477-481 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T7 | 516-520 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T10 | 1763-1774 | OrganismTaxon | denotes | hippocampus | NCBItxid:72046 |
| T11 | 1778-1782 | OrganismTaxon | denotes | rats | NCBItxid:10116|NCBItxid:10114|NCBItxid:10118 |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 6941 | 0-15 | ChemicalEntity | denotes | Metallothionein | MESH:D008668 |
| 6942 | 34-43 | GeneOrGeneProduct | denotes | caspase-3 | NCBIGene:25402 |
| 6943 | 57-65 | GeneOrGeneProduct | denotes | TNFalpha | NCBIGene:24835 |
| 6944 | 147-157 | ChemicalEntity | denotes | carmustine | MESH:D002330 |
| 6945 | 166-170 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 6946 | 264-279 | ChemicalEntity | denotes | metallothionein | MESH:D008668 |
| 6947 | 281-283 | ChemicalEntity | denotes | MT | MESH:D008668 |
| 6948 | 288-295 | ChemicalEntity | denotes | ZnSO(4) | MESH:D019287 |
| 6949 | 398-400 | ChemicalEntity | denotes | MT | MESH:D008668 |
| 6950 | 414-424 | ChemicalEntity | denotes | carmustine | MESH:D002330 |
| 6951 | 426-430 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6952 | 452-473 | DiseaseOrPhenotypicFeature | denotes | cognitive dysfunction | MESH:D003072 |
| 6953 | 477-481 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 6954 | 516-520 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 6955 | 665-669 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6956 | 715-722 | ChemicalEntity | denotes | ZnSO(4) | MESH:D019287 |
| 6957 | 780-784 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6958 | 832-836 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6959 | 947-954 | ChemicalEntity | denotes | ZnSO(4) | MESH:D019287 |
| 6960 | 1006-1010 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6961 | 1077-1081 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6962 | 1109-1156 | DiseaseOrPhenotypicFeature | denotes | deterioration of learning and short-term memory | MESH:D007859|MESH:D008569 |
| 6963 | 1247-1268 | GeneOrGeneProduct | denotes | glutathione reductase | NCBIGene:116686 |
| 6964 | 1270-1272 | GeneOrGeneProduct | denotes | GR | NCBIGene:116686 |
| 6965 | 1295-1306 | ChemicalEntity | denotes | glutathione | MESH:D005978 |
| 6966 | 1308-1311 | ChemicalEntity | denotes | GSH | MESH:D005978 |
| 6967 | 1328-1332 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6968 | 1364-1391 | GeneOrGeneProduct | denotes | tumor necrosis factor-alpha | NCBIGene:24835 |
| 6969 | 1393-1401 | GeneOrGeneProduct | denotes | TNFalpha | NCBIGene:24835 |
| 6970 | 1416-1418 | ChemicalEntity | denotes | MT | MESH:D008668 |
| 6971 | 1423-1438 | ChemicalEntity | denotes | malondialdehyde | MESH:D008315 |
| 6972 | 1440-1443 | ChemicalEntity | denotes | MDA | MESH:D008315 |
| 6973 | 1465-1474 | GeneOrGeneProduct | denotes | caspase-3 | NCBIGene:25402 |
| 6974 | 1525-1532 | ChemicalEntity | denotes | ZnSO(4) | MESH:D019287 |
| 6975 | 1559-1563 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6976 | 1586-1588 | GeneOrGeneProduct | denotes | GR | NCBIGene:116686 |
| 6977 | 1606-1609 | ChemicalEntity | denotes | GSH | MESH:D005978 |
| 6978 | 1665-1668 | ChemicalEntity | denotes | MDA | MESH:D008315 |
| 6979 | 1673-1681 | GeneOrGeneProduct | denotes | TNFalpha | NCBIGene:24835 |
| 6980 | 1709-1718 | GeneOrGeneProduct | denotes | caspase-3 | NCBIGene:25402 |
| 6981 | 1778-1782 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 6982 | 1796-1803 | ChemicalEntity | denotes | ZnSO(4) | MESH:D019287 |
| 6983 | 1806-1810 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6984 | 1828-1832 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6985 | 1865-1867 | ChemicalEntity | denotes | MT | MESH:D008668 |
| 6986 | 1884-1888 | ChemicalEntity | denotes | BCNU | MESH:D002330 |
| 6987 | 1909-1917 | DiseaseOrPhenotypicFeature | denotes | toxicity | MESH:D064420 |
| 6988 | 1934-1936 | GeneOrGeneProduct | denotes | GR | NCBIGene:116686 |
| 6989 | 1952-1955 | ChemicalEntity | denotes | GSH | MESH:D005978 |
| 6990 | 2007-2015 | GeneOrGeneProduct | denotes | TNFalpha | NCBIGene:24835 |
| 6991 | 2017-2020 | ChemicalEntity | denotes | MDA | MESH:D008315 |
| 6992 | 2025-2034 | GeneOrGeneProduct | denotes | caspase-3 | NCBIGene:25402 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 136-143 | DiseaseOrPhenotypicFeature | denotes | neurons | 0004466 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | GeneOrGeneProduct | denotes | Metallothionein |
| T2 | 26-33 | GeneOrGeneProduct | denotes | reduces |
| T3 | 34-43 | GeneOrGeneProduct | denotes | caspase-3 |
| T4 | 44-52 | GeneOrGeneProduct | denotes | activity |
| T5 | 57-65 | GeneOrGeneProduct | denotes | TNFalpha |
| T6 | 239-244 | GeneOrGeneProduct | denotes | other |
| T7 | 245-249 | GeneOrGeneProduct | denotes | hand |
| T8 | 264-279 | GeneOrGeneProduct | denotes | metallothionein |
| T9 | 281-283 | GeneOrGeneProduct | denotes | MT |
| T10 | 292-299 | GeneOrGeneProduct | denotes | (4) and |
| T11 | 398-400 | GeneOrGeneProduct | denotes | MT |
| T12 | 432-439 | GeneOrGeneProduct | denotes | induced |
| T13 | 485-490 | GeneOrGeneProduct | denotes | total |
| T14 | 497-501 | GeneOrGeneProduct | denotes | male |
| T15 | 509-515 | GeneOrGeneProduct | denotes | albino |
| T16 | 656-664 | GeneOrGeneProduct | denotes | later by |
| T17 | 841-843 | GeneOrGeneProduct | denotes | mg |
| T18 | 1015-1017 | GeneOrGeneProduct | denotes | mg |
| T19 | 1145-1149 | GeneOrGeneProduct | denotes | term |
| T20 | 1202-1206 | GeneOrGeneProduct | denotes | maze |
| T21 | 1247-1268 | GeneOrGeneProduct | denotes | glutathione reductase |
| T22 | 1270-1272 | GeneOrGeneProduct | denotes | GR |
| T23 | 1274-1282 | GeneOrGeneProduct | denotes | activity |
| T24 | 1287-1294 | GeneOrGeneProduct | denotes | reduced |
| T25 | 1295-1306 | GeneOrGeneProduct | denotes | glutathione |
| T26 | 1364-1391 | GeneOrGeneProduct | denotes | tumor necrosis factor-alpha |
| T27 | 1393-1401 | GeneOrGeneProduct | denotes | TNFalpha |
| T28 | 1416-1418 | GeneOrGeneProduct | denotes | MT |
| T29 | 1465-1474 | GeneOrGeneProduct | denotes | caspase-3 |
| T30 | 1475-1483 | GeneOrGeneProduct | denotes | activity |
| T31 | 1564-1571 | GeneOrGeneProduct | denotes | induced |
| T32 | 1586-1588 | GeneOrGeneProduct | denotes | GR |
| T33 | 1593-1602 | GeneOrGeneProduct | denotes | depletion |
| T34 | 1673-1681 | GeneOrGeneProduct | denotes | TNFalpha |
| T35 | 1697-1705 | GeneOrGeneProduct | denotes | activity |
| T36 | 1709-1718 | GeneOrGeneProduct | denotes | caspase-3 |
| T37 | 1865-1867 | GeneOrGeneProduct | denotes | MT |
| T38 | 1878-1883 | GeneOrGeneProduct | denotes | halts |
| T39 | 1889-1896 | GeneOrGeneProduct | denotes | induced |
| T40 | 1934-1936 | GeneOrGeneProduct | denotes | GR |
| T41 | 1956-1969 | GeneOrGeneProduct | denotes | depletion and |
| T42 | 2007-2015 | GeneOrGeneProduct | denotes | TNFalpha |
| T43 | 2025-2034 | GeneOrGeneProduct | denotes | caspase-3 |
| T44 | 2035-2043 | GeneOrGeneProduct | denotes | activity |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | GeneOrGeneProduct | denotes | Metallothionein |
| T2 | 34-43 | GeneOrGeneProduct | denotes | caspase-3 |
| T3 | 57-65 | GeneOrGeneProduct | denotes | TNFalpha |
| T4 | 239-244 | GeneOrGeneProduct | denotes | other |
| T5 | 245-249 | GeneOrGeneProduct | denotes | hand |
| T6 | 264-279 | GeneOrGeneProduct | denotes | metallothionein |
| T7 | 281-283 | GeneOrGeneProduct | denotes | MT |
| T8 | 398-400 | GeneOrGeneProduct | denotes | MT |
| T9 | 509-515 | GeneOrGeneProduct | denotes | albino |
| T10 | 1145-1149 | GeneOrGeneProduct | denotes | term |
| T11 | 1247-1268 | GeneOrGeneProduct | denotes | glutathione reductase |
| T12 | 1270-1272 | GeneOrGeneProduct | denotes | GR |
| T13 | 1287-1294 | GeneOrGeneProduct | denotes | reduced |
| T14 | 1295-1306 | GeneOrGeneProduct | denotes | glutathione |
| T15 | 1364-1391 | GeneOrGeneProduct | denotes | tumor necrosis factor-alpha |
| T16 | 1393-1401 | GeneOrGeneProduct | denotes | TNFalpha |
| T17 | 1416-1418 | GeneOrGeneProduct | denotes | MT |
| T18 | 1465-1474 | GeneOrGeneProduct | denotes | caspase-3 |
| T19 | 1586-1588 | GeneOrGeneProduct | denotes | GR |
| T20 | 1673-1681 | GeneOrGeneProduct | denotes | TNFalpha |
| T21 | 1709-1718 | GeneOrGeneProduct | denotes | caspase-3 |
| T22 | 1865-1867 | GeneOrGeneProduct | denotes | MT |
| T23 | 1934-1936 | GeneOrGeneProduct | denotes | GR |
| T24 | 2007-2015 | GeneOrGeneProduct | denotes | TNFalpha |
| T25 | 2025-2034 | GeneOrGeneProduct | denotes | caspase-3 |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 452-473 | DiseaseOrPhenotypicFeature | denotes | cognitive dysfunction | D060825 |
| T2 | 1364-1369 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T3 | 1370-1378 | DiseaseOrPhenotypicFeature | denotes | necrosis | D009336 |
| T4 | 1909-1917 | DiseaseOrPhenotypicFeature | denotes | toxicity | DISEASE |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | GeneOrGeneProduct | denotes | Metallothionein |
| T2 | 34-43 | GeneOrGeneProduct | denotes | caspase-3 |
| T3 | 57-65 | GeneOrGeneProduct | denotes | TNFalpha |
| T4 | 264-279 | GeneOrGeneProduct | denotes | metallothionein |
| T5 | 281-283 | GeneOrGeneProduct | denotes | MT |
| T6 | 398-400 | GeneOrGeneProduct | denotes | MT |
| T7 | 1247-1268 | GeneOrGeneProduct | denotes | glutathione reductase |
| T8 | 1270-1272 | GeneOrGeneProduct | denotes | GR |
| T9 | 1364-1391 | GeneOrGeneProduct | denotes | tumor necrosis factor-alpha |
| T10 | 1393-1401 | GeneOrGeneProduct | denotes | TNFalpha |
| T11 | 1416-1418 | GeneOrGeneProduct | denotes | MT |
| T12 | 1465-1474 | GeneOrGeneProduct | denotes | caspase-3 |
| T13 | 1586-1588 | GeneOrGeneProduct | denotes | GR |
| T14 | 1673-1681 | GeneOrGeneProduct | denotes | TNFalpha |
| T15 | 1709-1718 | GeneOrGeneProduct | denotes | caspase-3 |
| T16 | 1865-1867 | GeneOrGeneProduct | denotes | MT |
| T17 | 1934-1936 | GeneOrGeneProduct | denotes | GR |
| T18 | 2007-2015 | GeneOrGeneProduct | denotes | TNFalpha |
| T19 | 2025-2034 | GeneOrGeneProduct | denotes | caspase-3 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 281-283 | DiseaseOrPhenotypicFeature | denotes | MT | 0004992 |
| T2 | 398-400 | DiseaseOrPhenotypicFeature | denotes | MT | 0004992 |
| T3 | 1364-1369 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T4 | 1416-1418 | DiseaseOrPhenotypicFeature | denotes | MT | 0004992 |
| T5 | 1865-1867 | DiseaseOrPhenotypicFeature | denotes | MT | 0004992 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 452-473 | DiseaseOrPhenotypicFeature | denotes | cognitive dysfunction | D060825 |
| T2 | 1364-1369 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T3 | 1370-1378 | DiseaseOrPhenotypicFeature | denotes | necrosis | D009336 |
| T4 | 1909-1917 | DiseaseOrPhenotypicFeature | denotes | toxicity | DISEASE |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 452-473 | DiseaseOrPhenotypicFeature | denotes | cognitive dysfunction | D060825 |
| T2 | 1364-1369 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T3 | 1909-1917 | DiseaseOrPhenotypicFeature | denotes | toxicity | DISEASE |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 0-15 | ChemicalEntity | denotes | Metallothionein | ChemicalEntity |
| T2 | 147-157 | ChemicalEntity | denotes | carmustine | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T4 | 264-279 | ChemicalEntity | denotes | metallothionein | ChemicalEntity |
| T5 | 281-283 | ChemicalEntity | denotes | MT | ChemicalEntity |
| T6 | 288-295 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity |
| T7 | 398-400 | ChemicalEntity | denotes | MT | ChemicalEntity |
| T8 | 414-424 | ChemicalEntity | denotes | carmustine | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T10 | 426-430 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T12 | 620-633 | ChemicalEntity | denotes | normal saline | D000077330 |
| T13 | 665-669 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T15 | 715-722 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity |
| T16 | 747-760 | ChemicalEntity | denotes | normal saline | D000077330 |
| T17 | 780-784 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T19 | 832-836 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T21 | 885-898 | ChemicalEntity | denotes | normal saline | D000077330 |
| T22 | 947-954 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity |
| T23 | 979-992 | ChemicalEntity | denotes | normal saline | D000077330 |
| T24 | 1006-1010 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 |
| T26 | 1077-1081 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T28 | 1196-1201 | ChemicalEntity | denotes | water | D014867|http://purl.obolibrary.org/obo/CHEBI_15377 |
| T30 | 1247-1268 | ChemicalEntity | denotes | glutathione reductase | D005980 |
| T31 | 1270-1272 | ChemicalEntity | denotes | GR | D005980 |
| T32 | 1295-1306 | ChemicalEntity | denotes | glutathione | http://purl.obolibrary.org/obo/CHEBI_16856 |
| T33 | 1308-1311 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 |
| T34 | 1328-1332 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T36 | 1416-1418 | ChemicalEntity | denotes | MT | ChemicalEntity |
| T37 | 1423-1438 | ChemicalEntity | denotes | malondialdehyde | D008315 |
| T38 | 1440-1443 | ChemicalEntity | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274|D008315 |
| T40 | 1525-1532 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity |
| T41 | 1559-1563 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T43 | 1586-1588 | ChemicalEntity | denotes | GR | D005980 |
| T44 | 1606-1609 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 |
| T45 | 1665-1668 | ChemicalEntity | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274|D008315 |
| T47 | 1796-1803 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity |
| T48 | 1806-1810 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T50 | 1828-1832 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T52 | 1865-1867 | ChemicalEntity | denotes | MT | ChemicalEntity |
| T53 | 1884-1888 | ChemicalEntity | denotes | BCNU | D002330|http://purl.obolibrary.org/obo/CHEBI_3423 |
| T55 | 1934-1936 | ChemicalEntity | denotes | GR | D005980 |
| T56 | 1952-1955 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 |
| T57 | 2017-2020 | ChemicalEntity | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274|D008315 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 166-170 | OrganismTaxon | denotes | rats |
| T2 | 477-481 | OrganismTaxon | denotes | rats |
| T3 | 516-520 | OrganismTaxon | denotes | rats |
| T4 | 1778-1782 | OrganismTaxon | denotes | rats |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T57 | 2017-2020 | ChemicalEntity | denotes | MDA | D008315|http://purl.obolibrary.org/obo/CHEBI_566274 | |
| T56 | 1952-1955 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 | |
| T55 | 1934-1936 | ChemicalEntity | denotes | GR | D005980 | |
| T53 | 1884-1888 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T52 | 1865-1867 | ChemicalEntity | denotes | MT | ChemicalEntity | |
| T50 | 1828-1832 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T48 | 1806-1810 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T47 | 1796-1803 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity | |
| T45 | 1665-1668 | ChemicalEntity | denotes | MDA | D008315|http://purl.obolibrary.org/obo/CHEBI_566274 | |
| T44 | 1606-1609 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 | |
| T43 | 1586-1588 | ChemicalEntity | denotes | GR | D005980 | |
| T41 | 1559-1563 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T40 | 1525-1532 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity | |
| T38 | 1440-1443 | ChemicalEntity | denotes | MDA | D008315|http://purl.obolibrary.org/obo/CHEBI_566274 | |
| T37 | 1423-1438 | ChemicalEntity | denotes | malondialdehyde | D008315 | |
| T36 | 1416-1418 | ChemicalEntity | denotes | MT | ChemicalEntity | |
| T34 | 1328-1332 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T33 | 1308-1311 | ChemicalEntity | denotes | GSH | http://purl.obolibrary.org/obo/CHEBI_16856 | |
| T32 | 1295-1306 | ChemicalEntity | denotes | glutathione | http://purl.obolibrary.org/obo/CHEBI_16856 | |
| T31 | 1270-1272 | ChemicalEntity | denotes | GR | D005980 | |
| T30 | 1247-1268 | ChemicalEntity | denotes | glutathione reductase | D005980 | |
| T28 | 1196-1201 | ChemicalEntity | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377|D014867 | |
| T26 | 1077-1081 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T24 | 1006-1010 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T23 | 979-992 | ChemicalEntity | denotes | normal saline | D000077330 | |
| T22 | 947-954 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity | |
| T21 | 885-898 | ChemicalEntity | denotes | normal saline | D000077330 | |
| T19 | 832-836 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T17 | 780-784 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T16 | 747-760 | ChemicalEntity | denotes | normal saline | D000077330 | |
| T15 | 715-722 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity | |
| T13 | 665-669 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T12 | 620-633 | ChemicalEntity | denotes | normal saline | D000077330 | |
| T10 | 426-430 | ChemicalEntity | denotes | BCNU | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T8 | 414-424 | ChemicalEntity | denotes | carmustine | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T7 | 398-400 | ChemicalEntity | denotes | MT | ChemicalEntity | |
| T6 | 288-295 | ChemicalEntity | denotes | ZnSO(4) | ChemicalEntity | |
| T5 | 281-283 | ChemicalEntity | denotes | MT | ChemicalEntity | |
| T4 | 264-279 | ChemicalEntity | denotes | metallothionein | ChemicalEntity | |
| T2 | 147-157 | ChemicalEntity | denotes | carmustine | http://purl.obolibrary.org/obo/CHEBI_3423|D002330 | |
| T1 | 0-15 | ChemicalEntity | denotes | Metallothionein | ChemicalEntity | |
| T9905 | 2025-2034 | GeneOrGeneProduct | denotes | caspase-3 | ||
| T18 | 2007-2015 | GeneOrGeneProduct | denotes | TNFalpha | ||
| T27525 | 1934-1936 | GeneOrGeneProduct | denotes | GR | ||
| T66620 | 1865-1867 | GeneOrGeneProduct | denotes | MT | ||
| T52606 | 1709-1718 | GeneOrGeneProduct | denotes | caspase-3 | ||
| T14 | 1673-1681 | GeneOrGeneProduct | denotes | TNFalpha | ||
| T29705 | 1586-1588 | GeneOrGeneProduct | denotes | GR | ||
| T51380 | 1465-1474 | GeneOrGeneProduct | denotes | caspase-3 | ||
| T11 | 1416-1418 | GeneOrGeneProduct | denotes | MT | ||
| T46526 | 1393-1401 | GeneOrGeneProduct | denotes | TNFalpha | ||
| T9 | 1364-1391 | GeneOrGeneProduct | denotes | tumor necrosis factor-alpha | ||
| T42169 | 1270-1272 | GeneOrGeneProduct | denotes | GR | ||
| T90535 | 1247-1268 | GeneOrGeneProduct | denotes | glutathione reductase | ||
| T96481 | 398-400 | GeneOrGeneProduct | denotes | MT | ||
| T3810 | 281-283 | GeneOrGeneProduct | denotes | MT | ||
| T46587 | 264-279 | GeneOrGeneProduct | denotes | metallothionein | ||
| T3 | 57-65 | GeneOrGeneProduct | denotes | TNFalpha | ||
| T69279 | 34-43 | GeneOrGeneProduct | denotes | caspase-3 | ||
| T61624 | 0-15 | GeneOrGeneProduct | denotes | Metallothionein | ||
| T76609 | 1909-1917 | DiseaseOrPhenotypicFeature | denotes | toxicity | DISEASE | |
| T86412 | 1364-1369 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | |
| T48942 | 452-473 | DiseaseOrPhenotypicFeature | denotes | cognitive dysfunction | D060825 | |
| T62017 | 1778-1782 | OrganismTaxon | denotes | rats | ||
| T99153 | 516-520 | OrganismTaxon | denotes | rats | ||
| T11121 | 477-481 | OrganismTaxon | denotes | rats | ||
| T27953 | 166-170 | OrganismTaxon | denotes | rats |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 509-515 | HP_0001022 | denotes | albino |
| T2 | 1364-1369 | HP_0002664 | denotes | tumor |