PubMed:20008118
Annnotations
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 57-82 | http://www.uniprot.org/uniprot/P07288 | denotes | prostate-specific antigen |
| T10 | 1456-1459 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T11 | 1550-1553 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T12 | 1690-1693 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T13 | 57-82 | http://www.uniprot.org/uniprot/Q16305 | denotes | prostate-specific antigen |
| T14 | 129-154 | http://www.uniprot.org/uniprot/Q16305 | denotes | prostate-specific antigen |
| T15 | 156-159 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T16 | 281-284 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T17 | 505-508 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T18 | 559-562 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T19 | 771-774 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T2 | 129-154 | http://www.uniprot.org/uniprot/P07288 | denotes | prostate-specific antigen |
| T20 | 1081-1084 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T21 | 1379-1382 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T22 | 1456-1459 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T23 | 1550-1553 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T24 | 1690-1693 | http://www.uniprot.org/uniprot/Q9Y617 | denotes | PSA |
| T25 | 156-159 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T26 | 281-284 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T27 | 505-508 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T28 | 559-562 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T29 | 771-774 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T3 | 156-159 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T30 | 1081-1084 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T31 | 1379-1382 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T32 | 1456-1459 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T33 | 1550-1553 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T34 | 1690-1693 | http://www.uniprot.org/uniprot/P55786 | denotes | PSA |
| T4 | 281-284 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T5 | 505-508 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T53 | 1284-1288 | http://www.uniprot.org/uniprot/P19526 | denotes | FUT1 |
| T54 | 1299-1334 | http://www.uniprot.org/uniprot/Q8N4A0 | denotes | N-acetylgalactosaminyltransferase 4 |
| T55 | 1335-1343 | http://www.uniprot.org/uniprot/Q76KP1 | denotes | B4GALNT4 |
| T6 | 559-562 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T7 | 771-774 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T8 | 1081-1084 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
| T9 | 1379-1382 | http://www.uniprot.org/uniprot/P07288 | denotes | PSA |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 57-65 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T2 | 109-118 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostatic |
| T3 | 129-137 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T4 | 203-211 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T5 | 330-339 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostatic |
| T6 | 576-589 | http://purl.obolibrary.org/obo/MAT_0000057 | denotes | seminal fluid |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-126 | Sentence | denotes | alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer. |
| TextSentencer_T2 | 127-256 | Sentence | denotes | A prostate-specific antigen (PSA) is widely used as a diagnostic marker for prostate cancer (PC) because of its high specificity. |
| TextSentencer_T3 | 257-358 | Sentence | denotes | However, elevated serum PSA does not occur only in PC but also in benign prostatic hyperplasia (BPH). |
| TextSentencer_T4 | 359-509 | Sentence | denotes | Since the structural changes of N-glycans during carcinogenesis are common phenomena, we investigated whether PC-specific N-glycans are linked to PSA. |
| TextSentencer_T5 | 510-748 | Sentence | denotes | We first analyzed the carbohydrate structures of PSA derived from seminal fluid, serum of BPH and PC patients, and PC cell line, namely, LNCaP using eight lectin-immobilized columns and then with enzyme-linked immunosorbent assay (ELISA). |
| TextSentencer_T6 | 749-1107 | Sentence | denotes | The fraction of serum PSA from PC patients bound to both Fucalpha1-2Gal and betaGalNAc binding Trichosanthes japonica agglutinin-II (TJA-II) column, while that from BPH patients did not exhibit this binding ability, thereby implying that there is elevated expression of alpha1,2-fucosylation and beta-N-acetylgalactosaminylation of PSA during carcinogenesis. |
| TextSentencer_T7 | 1108-1345 | Sentence | denotes | We then performed a real-time polymerase chain reaction (PCR) and confirmed that these structural changes were responsible for the elevated expression of fucosyltransferase I (FUT1) and beta-N-acetylgalactosaminyltransferase 4(B4GALNT4). |
| TextSentencer_T8 | 1346-1504 | Sentence | denotes | Second, we measured TJA-II-bound PSA contents and the binding ratios of TJA-II column chromatography in serum PSA samples from 40 patients of both PC and BPH. |
| TextSentencer_T9 | 1505-1738 | Sentence | denotes | The results indicated that both TJA-II-bound PSA content and TJA-II binding ratios (%) could be used to discriminate between PC and BPH with more than 95% probability, and TJA-II-bound PSA can be regarded as a potential marker of PC. |
| T1 | 0-126 | Sentence | denotes | alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer. |
| T2 | 127-256 | Sentence | denotes | A prostate-specific antigen (PSA) is widely used as a diagnostic marker for prostate cancer (PC) because of its high specificity. |
| T3 | 257-358 | Sentence | denotes | However, elevated serum PSA does not occur only in PC but also in benign prostatic hyperplasia (BPH). |
| T4 | 359-509 | Sentence | denotes | Since the structural changes of N-glycans during carcinogenesis are common phenomena, we investigated whether PC-specific N-glycans are linked to PSA. |
| T5 | 510-748 | Sentence | denotes | We first analyzed the carbohydrate structures of PSA derived from seminal fluid, serum of BPH and PC patients, and PC cell line, namely, LNCaP using eight lectin-immobilized columns and then with enzyme-linked immunosorbent assay (ELISA). |
| T6 | 749-1107 | Sentence | denotes | The fraction of serum PSA from PC patients bound to both Fucalpha1-2Gal and betaGalNAc binding Trichosanthes japonica agglutinin-II (TJA-II) column, while that from BPH patients did not exhibit this binding ability, thereby implying that there is elevated expression of alpha1,2-fucosylation and beta-N-acetylgalactosaminylation of PSA during carcinogenesis. |
| T7 | 1108-1345 | Sentence | denotes | We then performed a real-time polymerase chain reaction (PCR) and confirmed that these structural changes were responsible for the elevated expression of fucosyltransferase I (FUT1) and beta-N-acetylgalactosaminyltransferase 4(B4GALNT4). |
| T8 | 1346-1504 | Sentence | denotes | Second, we measured TJA-II-bound PSA contents and the binding ratios of TJA-II column chromatography in serum PSA samples from 40 patients of both PC and BPH. |
| T9 | 1505-1738 | Sentence | denotes | The results indicated that both TJA-II-bound PSA content and TJA-II binding ratios (%) could be used to discriminate between PC and BPH with more than 95% probability, and TJA-II-bound PSA can be regarded as a potential marker of PC. |
| T1 | 0-126 | Sentence | denotes | alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer. |
| T2 | 127-256 | Sentence | denotes | A prostate-specific antigen (PSA) is widely used as a diagnostic marker for prostate cancer (PC) because of its high specificity. |
| T3 | 257-358 | Sentence | denotes | However, elevated serum PSA does not occur only in PC but also in benign prostatic hyperplasia (BPH). |
| T4 | 359-509 | Sentence | denotes | Since the structural changes of N-glycans during carcinogenesis are common phenomena, we investigated whether PC-specific N-glycans are linked to PSA. |
| T5 | 510-748 | Sentence | denotes | We first analyzed the carbohydrate structures of PSA derived from seminal fluid, serum of BPH and PC patients, and PC cell line, namely, LNCaP using eight lectin-immobilized columns and then with enzyme-linked immunosorbent assay (ELISA). |
| T6 | 749-1107 | Sentence | denotes | The fraction of serum PSA from PC patients bound to both Fucalpha1-2Gal and betaGalNAc binding Trichosanthes japonica agglutinin-II (TJA-II) column, while that from BPH patients did not exhibit this binding ability, thereby implying that there is elevated expression of alpha1,2-fucosylation and beta-N-acetylgalactosaminylation of PSA during carcinogenesis. |
| T7 | 1108-1345 | Sentence | denotes | We then performed a real-time polymerase chain reaction (PCR) and confirmed that these structural changes were responsible for the elevated expression of fucosyltransferase I (FUT1) and beta-N-acetylgalactosaminyltransferase 4(B4GALNT4). |
| T8 | 1346-1504 | Sentence | denotes | Second, we measured TJA-II-bound PSA contents and the binding ratios of TJA-II column chromatography in serum PSA samples from 40 patients of both PC and BPH. |
| T9 | 1505-1738 | Sentence | denotes | The results indicated that both TJA-II-bound PSA content and TJA-II binding ratios (%) could be used to discriminate between PC and BPH with more than 95% probability, and TJA-II-bound PSA can be regarded as a potential marker of PC. |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 203-218 | HP_0012125 | denotes | prostate cancer |
| T2 | 212-218 | HP_0002664 | denotes | cancer |
| T3 | 323-351 | HP_0008711 | denotes | benign prostatic hyperplasia |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 330-351 | http://purl.bioontology.org/ontology/ICD10/N40 | denotes | prostatic hyperplasia |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 30-56 | FMAID:82786 | denotes | N-acetylgalactosaminylated |
| _T2 | 30-56 | FMAID:196780 | denotes | N-acetylgalactosaminylated |
| _T3 | 57-65 | FMAID:97485 | denotes | prostate |
| _T4 | 57-65 | FMAID:9600 | denotes | prostate |
| _T5 | 109-118 | FMAID:97485 | denotes | prostatic |
| _T6 | 109-118 | FMAID:9600 | denotes | prostatic |
| _T7 | 129-137 | FMAID:97485 | denotes | prostate |
| _T8 | 129-137 | FMAID:9600 | denotes | prostate |
| _T9 | 203-211 | FMAID:9600 | denotes | prostate |
| _T10 | 203-211 | FMAID:97485 | denotes | prostate |
| _T11 | 275-280 | FMAID:167330 | denotes | serum |
| _T12 | 330-339 | FMAID:9600 | denotes | prostatic |
| _T13 | 330-339 | FMAID:97485 | denotes | prostatic |
| _T14 | 532-544 | FMAID:197276 | denotes | carbohydrate |
| _T15 | 532-544 | FMAID:82737 | denotes | carbohydrate |
| _T16 | 576-589 | FMAID:167309 | denotes | seminal fluid |
| _T17 | 591-596 | FMAID:167330 | denotes | serum |
| _T18 | 684-691 | FMAID:183891 | denotes | columns |
| _T19 | 684-691 | FMAID:76737 | denotes | columns |
| _T20 | 765-770 | FMAID:167330 | denotes | serum |
| _T21 | 890-896 | FMAID:76737 | denotes | column |
| _T22 | 890-896 | FMAID:183891 | denotes | column |
| _T23 | 1050-1077 | FMAID:196780 | denotes | N-acetylgalactosaminylation |
| _T24 | 1050-1077 | FMAID:82786 | denotes | N-acetylgalactosaminylation |
| _T25 | 1425-1431 | FMAID:76737 | denotes | column |
| _T26 | 1425-1431 | FMAID:183891 | denotes | column |
| _T27 | 1450-1455 | FMAID:167330 | denotes | serum |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 156-159 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T2 | 281-284 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T3 | 505-508 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T4 | 559-562 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T5 | 771-774 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T6 | 1081-1084 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T7 | 1379-1382 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T8 | 1456-1459 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T9 | 1550-1553 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T10 | 1690-1693 | http://www.uniprot.org/uniprot/Q11011 | denotes | PSA |
| T11 | 220-222 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T12 | 308-310 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T13 | 469-471 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T14 | 608-610 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T15 | 625-627 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T16 | 780-782 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T17 | 1493-1495 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T18 | 1630-1632 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
| T19 | 1735-1737 | http://www.uniprot.org/uniprot/Q9R0M4 | denotes | PC |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-29 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T2 | 25-29 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T3 | 119-125 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
| T4 | 212-218 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
| T5 | 858-866 | http://purl.bioontology.org/ontology/NCBITAXON/73258 | denotes | japonica |
| T6 | 1045-1049 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T7 | 1045-1049 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T8 | 1294-1298 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T9 | 1294-1298 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 9-20 | http://purl.obolibrary.org/obo/GO_0036065 | denotes | Fucosylated |
| T2 | 1028-1040 | http://purl.obolibrary.org/obo/GO_0036065 | denotes | fucosylation |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 836-843 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T2 | 948-955 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T3 | 1400-1407 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T4 | 1573-1580 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T5 | 836-843 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T6 | 948-955 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T7 | 1400-1407 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T8 | 1573-1580 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T9 | 836-843 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T10 | 948-955 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T11 | 1400-1407 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T12 | 1573-1580 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T13 | 836-843 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T14 | 948-955 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T15 | 1400-1407 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T16 | 1573-1580 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 628-632 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 275-280 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| T2 | 591-596 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| T3 | 765-770 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| T4 | 1450-1455 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| T5 | 576-589 | http://purl.obolibrary.org/obo/UBERON_0006530 | denotes | seminal fluid |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_20008118_1_0 | 129-154 | expanded | denotes | prostate-specific antigen |
| SS2_20008118_1_0 | 156-159 | abbr | denotes | PSA |
| SS1_20008118_1_1 | 203-218 | expanded | denotes | prostate cancer |
| SS2_20008118_1_1 | 220-222 | abbr | denotes | PC |
| SS1_20008118_2_0 | 323-351 | expanded | denotes | benign prostatic hyperplasia |
| SS2_20008118_2_0 | 353-356 | abbr | denotes | BPH |
| SS1_20008118_4_0 | 706-739 | expanded | denotes | enzyme-linked immunosorbent assay |
| SS2_20008118_4_0 | 741-746 | abbr | denotes | ELISA |
| SS1_20008118_5_0 | 844-880 | expanded | denotes | Trichosanthes japonica agglutinin-II |
| SS2_20008118_5_0 | 882-888 | abbr | denotes | TJA-II |
| SS1_20008118_6_0 | 1294-1334 | expanded | denotes | beta-N-acetylgalactosaminyltransferase 4 |
| SS2_20008118_6_0 | 1335-1343 | abbr | denotes | B4GALNT4 |
| SS1_20008118_6_1 | 1138-1163 | expanded | denotes | polymerase chain reaction |
| SS2_20008118_6_1 | 1165-1168 | abbr | denotes | PCR |
| AE1_20008118_1_0 | SS1_20008118_1_0 | SS2_20008118_1_0 | abbreviatedTo | prostate-specific antigen,PSA |
| AE1_20008118_1_1 | SS1_20008118_1_1 | SS2_20008118_1_1 | abbreviatedTo | prostate cancer,PC |
| AE1_20008118_2_0 | SS1_20008118_2_0 | SS2_20008118_2_0 | abbreviatedTo | benign prostatic hyperplasia,BPH |
| AE1_20008118_4_0 | SS1_20008118_4_0 | SS2_20008118_4_0 | abbreviatedTo | enzyme-linked immunosorbent assay,ELISA |
| AE1_20008118_5_0 | SS1_20008118_5_0 | SS2_20008118_5_0 | abbreviatedTo | Trichosanthes japonica agglutinin-II,TJA-II |
| AE1_20008118_6_0 | SS1_20008118_6_0 | SS2_20008118_6_0 | abbreviatedTo | beta-N-acetylgalactosaminyltransferase 4,B4GALNT4 |
| AE1_20008118_6_1 | SS1_20008118_6_1 | SS2_20008118_6_1 | abbreviatedTo | polymerase chain reaction,PCR |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 75-82 | http://edamontology.org/topic_2830 | denotes | antigen |
| T2 | 119-125 | http://edamontology.org/topic_2640 | denotes | cancer |
| T3 | 147-154 | http://edamontology.org/topic_2830 | denotes | antigen |
| T4 | 181-198 | http://edamontology.org/topic_3360 | denotes | diagnostic marker |
| T5 | 212-218 | http://edamontology.org/topic_2640 | denotes | cancer |
| T6 | 532-544 | http://edamontology.org/topic_0152 | denotes | carbohydrate |
| T7 | 1138-1163 | http://edamontology.org/topic_0195 | denotes | polymerase chain reaction |
| T8 | 1165-1168 | http://edamontology.org/topic_0195 | denotes | PCR |
| T9 | 1460-1467 | http://edamontology.org/topic_3277 | denotes | samples |
| T10 | 1660-1671 | http://edamontology.org/topic_2269 | denotes | probability |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 369-379 | http://edamontology.org/data_0883 | denotes | structural |
| T2 | 532-555 | http://edamontology.org/data_1462 | denotes | carbohydrate structures |
| T3 | 545-555 | http://edamontology.org/data_0883 | denotes | structures |
| T4 | 628-645 | http://edamontology.org/data_2316 | denotes | cell line, namely |
| T5 | 639-645 | http://edamontology.org/data_2099 | denotes | namely |
| T6 | 1195-1205 | http://edamontology.org/data_0883 | denotes | structural |
| T7 | 1357-1365 | http://edamontology.org/data_3108 | denotes | measured |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 57-65 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T2 | 109-118 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostatic |
| T3 | 129-137 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T4 | 203-211 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostate |
| T5 | 330-339 | http://purl.obolibrary.org/obo/MAT_0000078 | denotes | prostatic |
| T6 | 576-589 | http://purl.obolibrary.org/obo/MAT_0000057 | denotes | seminal fluid |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 391-400 | http://rdf.glycoinfo.org/glycan/G00027MO | denotes | N-glycans |
| T2 | 481-490 | http://rdf.glycoinfo.org/glycan/G00027MO | denotes | N-glycans |
Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| Lectin_T1 | 156-159 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T2 | 281-284 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T3 | 505-508 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T4 | 559-562 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T5 | 771-774 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T6 | 1081-1084 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T7 | 1379-1382 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T8 | 1456-1459 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T9 | 1550-1553 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T10 | 1690-1693 | https://acgg.asia/db/lfdb/LfDB0181 | denotes | PSA |
| Lectin_T11 | 882-888 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
| Lectin_T12 | 1366-1372 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
| Lectin_T13 | 1418-1424 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
| Lectin_T14 | 1537-1543 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
| Lectin_T15 | 1566-1572 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
| Lectin_T16 | 1677-1683 | https://acgg.asia/db/lfdb/LfDB0225 | denotes | TJA-II |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 275-280 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| PD-UBERON-AE-B_T2 | 591-596 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| PD-UBERON-AE-B_T3 | 765-770 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| PD-UBERON-AE-B_T4 | 1450-1455 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| PD-UBERON-AE-B_T5 | 576-589 | http://purl.obolibrary.org/obo/UBERON_0006530 | denotes | seminal fluid |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 109-125 | Disease | denotes | prostatic cancer | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T2 | 203-218 | Disease | denotes | prostate cancer | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T3 | 220-222 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T4 | 308-310 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T5 | 323-351 | Disease | denotes | benign prostatic hyperplasia | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T6 | 353-356 | Disease | denotes | BPH | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T7 | 469-471 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T8 | 600-603 | Disease | denotes | BPH | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T9 | 608-610 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T10 | 625-627 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T11 | 780-782 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T12 | 914-917 | Disease | denotes | BPH | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T13 | 1493-1495 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T14 | 1500-1503 | Disease | denotes | BPH | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T15 | 1630-1632 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
| T16 | 1637-1640 | Disease | denotes | BPH | http://purl.obolibrary.org/obo/MONDO_0010811 |
| T17 | 1735-1737 | Disease | denotes | PC | http://purl.obolibrary.org/obo/MONDO_0008315 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 57-65 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
| T2 | 109-118 | Body_part | denotes | prostatic | http://purl.obolibrary.org/obo/MAT_0000078 |
| T3 | 129-137 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
| T4 | 203-211 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/MAT_0000078 |
| T5 | 330-339 | Body_part | denotes | prostatic | http://purl.obolibrary.org/obo/MAT_0000078 |
| T6 | 576-589 | Body_part | denotes | seminal fluid | http://purl.obolibrary.org/obo/MAT_0000057 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 109-125 | Phenotype | denotes | prostatic cancer | HP:0012125 |
| T2 | 203-218 | Phenotype | denotes | prostate cancer | HP:0012125 |
| T3 | 220-222 | Phenotype | denotes | PC | HP:0012125 |
| T4 | 308-310 | Phenotype | denotes | PC | HP:0012125 |
| T5 | 323-351 | Phenotype | denotes | benign prostatic hyperplasia | HP:0008711 |
| T6 | 353-356 | Phenotype | denotes | BPH | HP:0008711 |
| T7 | 469-471 | Phenotype | denotes | PC | HP:0012125 |
| T8 | 600-603 | Phenotype | denotes | BPH | HP:0008711 |
| T9 | 608-610 | Phenotype | denotes | PC | HP:0012125 |
| T10 | 625-627 | Phenotype | denotes | PC | HP:0012125 |
| T11 | 780-782 | Phenotype | denotes | PC | HP:0012125 |
| T12 | 914-917 | Phenotype | denotes | BPH | HP:0008711 |
| T13 | 1493-1495 | Phenotype | denotes | PC | HP:0012125 |
| T14 | 1500-1503 | Phenotype | denotes | BPH | HP:0008711 |
| T15 | 1630-1632 | Phenotype | denotes | PC | HP:0012125 |
| T16 | 1637-1640 | Phenotype | denotes | BPH | HP:0008711 |
| T17 | 1735-1737 | Phenotype | denotes | PC | HP:0012125 |
Lectin-Jamboree-small
| Id | Subject | Object | Predicate | Lexical cue | glycosmos_id |
|---|---|---|---|---|---|
| T1 | 156-159 | Lectin | denotes | PSA | GL_000021 |
| T2 | 281-284 | Lectin | denotes | PSA | GL_000021 |
| T3 | 505-508 | Lectin | denotes | PSA | GL_000021 |
| T4 | 559-562 | Lectin | denotes | PSA | GL_000021 |
| T5 | 771-774 | Lectin | denotes | PSA | GL_000021 |
| T6 | 882-888 | Lectin | denotes | TJA-II | GL_000079 |
| T7 | 1081-1084 | Lectin | denotes | PSA | GL_000021 |
| T8 | 1366-1372 | Lectin | denotes | TJA-II | GL_000079 |
| T9 | 1379-1382 | Lectin | denotes | PSA | GL_000021 |
| T10 | 1418-1424 | Lectin | denotes | TJA-II | GL_000079 |
| T11 | 1456-1459 | Lectin | denotes | PSA | GL_000021 |
| T12 | 1537-1543 | Lectin | denotes | TJA-II | GL_000079 |
| T13 | 1550-1553 | Lectin | denotes | PSA | GL_000021 |
| T14 | 1566-1572 | Lectin | denotes | TJA-II | GL_000079 |
| T15 | 1677-1683 | Lectin | denotes | TJA-II | GL_000079 |
| T16 | 1690-1693 | Lectin | denotes | PSA | GL_000021 |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-126 | Sentence | denotes | alpha1,2-Fucosylated and beta-N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer. |
| T2 | 127-256 | Sentence | denotes | A prostate-specific antigen (PSA) is widely used as a diagnostic marker for prostate cancer (PC) because of its high specificity. |
| T3 | 257-358 | Sentence | denotes | However, elevated serum PSA does not occur only in PC but also in benign prostatic hyperplasia (BPH). |
| T4 | 359-509 | Sentence | denotes | Since the structural changes of N-glycans during carcinogenesis are common phenomena, we investigated whether PC-specific N-glycans are linked to PSA. |
| T5 | 510-748 | Sentence | denotes | We first analyzed the carbohydrate structures of PSA derived from seminal fluid, serum of BPH and PC patients, and PC cell line, namely, LNCaP using eight lectin-immobilized columns and then with enzyme-linked immunosorbent assay (ELISA). |
| T6 | 749-1107 | Sentence | denotes | The fraction of serum PSA from PC patients bound to both Fucalpha1-2Gal and betaGalNAc binding Trichosanthes japonica agglutinin-II (TJA-II) column, while that from BPH patients did not exhibit this binding ability, thereby implying that there is elevated expression of alpha1,2-fucosylation and beta-N-acetylgalactosaminylation of PSA during carcinogenesis. |
| T7 | 1108-1345 | Sentence | denotes | We then performed a real-time polymerase chain reaction (PCR) and confirmed that these structural changes were responsible for the elevated expression of fucosyltransferase I (FUT1) and beta-N-acetylgalactosaminyltransferase 4(B4GALNT4). |
| T8 | 1346-1504 | Sentence | denotes | Second, we measured TJA-II-bound PSA contents and the binding ratios of TJA-II column chromatography in serum PSA samples from 40 patients of both PC and BPH. |
| T9 | 1505-1738 | Sentence | denotes | The results indicated that both TJA-II-bound PSA content and TJA-II binding ratios (%) could be used to discriminate between PC and BPH with more than 95% probability, and TJA-II-bound PSA can be regarded as a potential marker of PC. |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 844-857 | OrganismTaxon | denotes | Trichosanthes | 3676 |
| T2 | 858-866 | OrganismTaxon | denotes | japonica | 73258 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 57-65 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T2 | 129-137 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T3 | 203-211 | Body_part | denotes | prostate | http://purl.obolibrary.org/obo/UBERON_0002367 |
| T4 | 576-589 | Body_part | denotes | seminal fluid | http://purl.obolibrary.org/obo/UBERON_0006530|http://purl.obolibrary.org/obo/UBERON_0010143 |