PubMed:20006623
Annnotations
c_corpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | PR:Q8WWM7 | denotes | A 2D |
| T2 | 0-4 | PR:000004506 | denotes | A 2D |
| T3 | 26-32 | UBERON:0000310 | denotes | breast |
| T6 | 33-57 | D002285 | denotes | ductal carcinoma in situ |
| T7 | 33-57 | D002285 | denotes | ductal carcinoma in situ |
| T13 | 59-63 | CVCL_5552 | denotes | DCIS |
| T12 | 59-63 | D002285 | denotes | DCIS |
| T14 | 59-63 | D002285 | denotes | DCIS |
| T17 | 100-117 | D002278 | denotes | carcinoma in situ |
| T18 | 100-117 | D002278 | denotes | carcinoma in situ |
| T20 | 119-123 | CVCL_5552 | denotes | DCIS |
| T19 | 119-123 | D002285 | denotes | DCIS |
| T21 | 119-123 | D002285 | denotes | DCIS |
| T22 | 132-138 | UBERON:0000310 | denotes | breast |
| T23 | 157-162 | D009369 | denotes | tumor |
| T24 | 157-162 | D009369 | denotes | tumor |
| T25 | 231-235 | UBERON:0000025 | denotes | duct |
| T26 | 231-235 | UBERON:0000058 | denotes | duct |
| T28 | 267-271 | CVCL_5552 | denotes | DCIS |
| T27 | 267-271 | D002285 | denotes | DCIS |
| T29 | 267-271 | D002285 | denotes | DCIS |
| T31 | 428-432 | CVCL_5552 | denotes | DCIS |
| T30 | 428-432 | D002285 | denotes | DCIS |
| T32 | 428-432 | D002285 | denotes | DCIS |
| T33 | 562-566 | PR:Q8WWM7 | denotes | a 2D |
| T34 | 562-566 | PR:000004506 | denotes | a 2D |
| T36 | 609-613 | CVCL_5552 | denotes | DCIS |
| T35 | 609-613 | D002285 | denotes | DCIS |
| T37 | 609-613 | D002285 | denotes | DCIS |
| T38 | 630-636 | UBERON:0000310 | denotes | breast |
| T39 | 637-641 | UBERON:0000025 | denotes | duct |
| T40 | 637-641 | UBERON:0000058 | denotes | duct |
| T41 | 770-783 | UBERON:2000098 | denotes | proliferation |
| T42 | 785-794 | GO:0097194 | denotes | apoptosis |
| T43 | 785-794 | GO:0006915 | denotes | apoptosis |
| T44 | 796-804 | GO:0019835 | denotes | necrosis |
| T45 | 796-804 | GO:0008219 | denotes | necrosis |
| T48 | 796-804 | GO:0008220 | denotes | necrosis |
| T49 | 796-804 | GO:0001906 | denotes | necrosis |
| T50 | 796-804 | GO:0070265 | denotes | necrosis |
| T46 | 796-804 | D009336 | denotes | necrosis |
| T47 | 796-804 | D009336 | denotes | necrosis |
| T51 | 810-823 | GO:0007163 | denotes | cell polarity |
| T53 | 937-941 | CVCL_5552 | denotes | DCIS |
| T52 | 937-941 | D002285 | denotes | DCIS |
| T54 | 937-941 | D002285 | denotes | DCIS |
| T55 | 1033-1039 | D009369 | denotes | tumors |
| T56 | 1033-1039 | D009369 | denotes | tumors |
| T58 | 1198-1202 | CVCL_5552 | denotes | DCIS |
| T57 | 1198-1202 | D002285 | denotes | DCIS |
| T59 | 1198-1202 | D002285 | denotes | DCIS |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 157-162 | HP_0002664 | denotes | tumor |
| T2 | 1033-1039 | HP_0002664 | denotes | tumors |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_20006623_0_0 | 33-57 | expanded | denotes | ductal carcinoma in situ |
| SS2_20006623_0_0 | 59-63 | abbr | denotes | DCIS |
| SS1_20006623_1_0 | 93-117 | expanded | denotes | Ductal carcinoma in situ |
| SS2_20006623_1_0 | 119-123 | abbr | denotes | DCIS |
| AE1_20006623_0_0 | SS1_20006623_0_0 | SS2_20006623_0_0 | abbreviatedTo | ductal carcinoma in situ,DCIS |
| AE1_20006623_1_0 | SS1_20006623_1_0 | SS2_20006623_1_0 | abbreviatedTo | Ductal carcinoma in situ,DCIS |
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 93-236 | DRI_Background | denotes | Ductal carcinoma in situ (DCIS) of the breast is a non-invasive tumor in which cells proliferate abnormally, but remain confined within a duct. |
| T2 | 237-462 | DRI_Background | denotes | Although four distinguishable DCIS morphologies are recognized, the mechanisms that generate these different morphological classes remain unclear, and consequently the prognostic strength of DCIS classification is not strong. |
| T3 | 463-642 | DRI_Challenge | denotes | To improve the understanding of the relation between morphology and time course, we have developed a 2D in silico particle model of the growth of DCIS within a single breast duct. |
| T4 | 643-824 | DRI_Background | denotes | This model considers mechanical effects such as cellular adhesion and intra-ductal pressure, and biological features including proliferation, apoptosis, necrosis, and cell polarity. |
| T5 | 825-1006 | DRI_Outcome | denotes | Using this model, we find that different regions of parameter space generate distinct morphological subtypes of DCIS, so elucidating the relation between morphology and time course. |
| T6 | 1007-1215 | DRI_Outcome | denotes | Furthermore, we find that tumors with similar architectures may in fact be produced through different mechanisms, and we propose future work to further disentangle the mechanisms involved in DCIS progression. |