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PubMed:19957053 JSONTXT

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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
T2 107-118 Sentence denotes BACKGROUND:
T3 119-189 Sentence denotes Vasopressor agents are used to correct anesthesia-induced hypotension.
T4 190-324 Sentence denotes We describe the effect of phenylephrine and ephedrine on frontal lobe oxygenation (S(c)O(2)) following anesthesia-induced hypotension.
T5 325-333 Sentence denotes METHODS:
T6 334-560 Sentence denotes Following induction of anesthesia by fentanyl (0.15 mg kg(-1)) and propofol (2.0 mg kg(-1)), 13 patients received phenylephrine (0.1 mg iv) and 12 patients received ephedrine (10 mg iv) to restore mean arterial pressure (MAP).
T7 561-680 Sentence denotes Heart rate (HR), MAP, stroke volume (SV), cardiac output (CO), and frontal lobe oxygenation (S(c)O(2)) were registered.
T8 681-689 Sentence denotes RESULTS:
T9 690-806 Sentence denotes Induction of anesthesia was followed by a decrease in MAP, HR, SV, and CO concomitant with an elevation in S(c)O(2).
T10 807-914 Sentence denotes After administration of phenylephrine, MAP increased (51 +/- 12 to 81 +/- 13 mmHg; P < 0.001; mean +/- SD).
T11 915-1062 Sentence denotes However, a 14% (from 70 +/- 8% to 60 +/- 7%) reduction in S(c)O(2) (P < 0.05) followed with no change in CO (3.7 +/- 1.1 to 3.4 +/- 0.9 l min(-1)).
T12 1063-1243 Sentence denotes The administration of ephedrine led to a similar increase in MAP (53 +/- 9 to 79 +/- 8 mmHg; P < 0.001), restored CO (3.2 +/- 1.2 to 5.0 +/- 1.3 l min(-1)), and preserved S(c)O(2).
T13 1244-1256 Sentence denotes CONCLUSIONS:
T14 1257-1461 Sentence denotes The utilization of phenylephrine to correct hypotension induced by anesthesia has a negative impact on S(c)O(2) while ephedrine maintains frontal lobe oxygenation potentially related to an increase in CO.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 749-755 OrganismTaxon denotes HR, SV NCBItxid:11250|NCBItxid:112228

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
6808 0-13 ChemicalEntity denotes Phenylephrine MESH:D010656
6809 22-31 ChemicalEntity denotes ephedrine MESH:D004809
6810 94-105 DiseaseOrPhenotypicFeature denotes hypotension MESH:D007022
6811 177-188 DiseaseOrPhenotypicFeature denotes hypotension MESH:D007022
6812 216-229 ChemicalEntity denotes phenylephrine MESH:D010656
6813 234-243 ChemicalEntity denotes ephedrine MESH:D004809
6814 312-323 DiseaseOrPhenotypicFeature denotes hypotension MESH:D007022
6815 371-379 ChemicalEntity denotes fentanyl MESH:D005283
6816 401-409 ChemicalEntity denotes propofol MESH:D015742
6817 430-438 OrganismTaxon denotes patients NCBITaxon:9606
6818 448-461 ChemicalEntity denotes phenylephrine MESH:D010656
6819 481-489 OrganismTaxon denotes patients NCBITaxon:9606
6820 499-508 ChemicalEntity denotes ephedrine MESH:D004809
6821 583-589 DiseaseOrPhenotypicFeature denotes stroke MESH:D020521
6822 831-844 ChemicalEntity denotes phenylephrine MESH:D010656
6823 1085-1094 ChemicalEntity denotes ephedrine MESH:D004809
6824 1276-1289 ChemicalEntity denotes phenylephrine MESH:D010656
6825 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension MESH:D007022
6826 1375-1384 ChemicalEntity denotes ephedrine MESH:D004809

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 32-39 GeneOrGeneProduct denotes reduces
T2 48-52 GeneOrGeneProduct denotes lobe
T3 86-93 GeneOrGeneProduct denotes induced
T4 169-176 GeneOrGeneProduct denotes induced
T5 255-259 GeneOrGeneProduct denotes lobe
T6 273-281 GeneOrGeneProduct denotes S(c)O(2)
T7 304-311 GeneOrGeneProduct denotes induced
T8 325-332 GeneOrGeneProduct denotes METHODS
T9 386-388 GeneOrGeneProduct denotes mg
T10 415-417 GeneOrGeneProduct denotes mg
T11 467-469 GeneOrGeneProduct denotes mg
T12 513-515 GeneOrGeneProduct denotes mg
T13 555-558 GeneOrGeneProduct denotes MAP
T14 561-566 GeneOrGeneProduct denotes Heart
T15 578-581 GeneOrGeneProduct denotes MAP
T16 636-640 GeneOrGeneProduct denotes lobe
T17 654-662 GeneOrGeneProduct denotes S(c)O(2)
T18 744-747 GeneOrGeneProduct denotes MAP
T19 797-805 GeneOrGeneProduct denotes S(c)O(2)
T20 846-849 GeneOrGeneProduct denotes MAP
T21 973-981 GeneOrGeneProduct denotes S(c)O(2)
T22 1053-1060 GeneOrGeneProduct denotes min(-1)
T23 1104-1111 GeneOrGeneProduct denotes similar
T24 1124-1127 GeneOrGeneProduct denotes MAP
T25 1210-1217 GeneOrGeneProduct denotes min(-1)
T26 1234-1242 GeneOrGeneProduct denotes S(c)O(2)
T27 1313-1320 GeneOrGeneProduct denotes induced
T28 1335-1340 GeneOrGeneProduct denotes has a
T29 1350-1356 GeneOrGeneProduct denotes impact
T30 1360-1368 GeneOrGeneProduct denotes S(c)O(2)
T31 1403-1407 GeneOrGeneProduct denotes lobe

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 48-52 GeneOrGeneProduct denotes lobe
T2 255-259 GeneOrGeneProduct denotes lobe
T3 561-566 GeneOrGeneProduct denotes Heart
T4 636-640 GeneOrGeneProduct denotes lobe
T5 1104-1111 GeneOrGeneProduct denotes similar
T6 1350-1356 GeneOrGeneProduct denotes impact
T7 1403-1407 GeneOrGeneProduct denotes lobe

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 94-105 DiseaseOrPhenotypicFeature denotes hypotension D007022
T2 177-188 DiseaseOrPhenotypicFeature denotes hypotension D007022
T3 312-323 DiseaseOrPhenotypicFeature denotes hypotension D007022
T4 583-589 DiseaseOrPhenotypicFeature denotes stroke D020521
T5 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension D007022

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 94-105 DiseaseOrPhenotypicFeature denotes hypotension 0005468
T2 177-188 DiseaseOrPhenotypicFeature denotes hypotension 0005468
T3 312-323 DiseaseOrPhenotypicFeature denotes hypotension 0005468
T4 555-558 DiseaseOrPhenotypicFeature denotes MAP 0012041
T5 578-581 DiseaseOrPhenotypicFeature denotes MAP 0012041
T6 583-589 DiseaseOrPhenotypicFeature denotes stroke 0005098
T7 744-747 DiseaseOrPhenotypicFeature denotes MAP 0012041
T8 846-849 DiseaseOrPhenotypicFeature denotes MAP 0012041
T9 910-912 DiseaseOrPhenotypicFeature denotes SD 0011449
T10 1124-1127 DiseaseOrPhenotypicFeature denotes MAP 0012041
T11 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension 0005468

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 94-105 DiseaseOrPhenotypicFeature denotes hypotension D007022
T2 177-188 DiseaseOrPhenotypicFeature denotes hypotension D007022
T3 312-323 DiseaseOrPhenotypicFeature denotes hypotension D007022
T4 583-589 DiseaseOrPhenotypicFeature denotes stroke DISEASE|D020521
T6 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension D007022

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 94-105 DiseaseOrPhenotypicFeature denotes hypotension D007022
T2 177-188 DiseaseOrPhenotypicFeature denotes hypotension D007022
T3 312-323 DiseaseOrPhenotypicFeature denotes hypotension D007022
T4 583-589 DiseaseOrPhenotypicFeature denotes stroke D020521
T5 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension D007022

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-13 ChemicalEntity denotes Phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093
T2 22-31 ChemicalEntity denotes ephedrine D004809
T3 216-229 ChemicalEntity denotes phenylephrine D010656|http://purl.obolibrary.org/obo/CHEBI_8093
T5 234-243 ChemicalEntity denotes ephedrine D004809
T6 371-379 ChemicalEntity denotes fentanyl D005283|http://purl.obolibrary.org/obo/CHEBI_119915
T8 401-409 ChemicalEntity denotes propofol D015742|http://purl.obolibrary.org/obo/CHEBI_44915
T10 448-461 ChemicalEntity denotes phenylephrine D010656|http://purl.obolibrary.org/obo/CHEBI_8093
T12 499-508 ChemicalEntity denotes ephedrine D004809
T13 555-558 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T14 578-581 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T15 619-621 ChemicalEntity denotes CO D002248
T16 744-747 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T17 761-763 ChemicalEntity denotes CO D002248
T18 831-844 ChemicalEntity denotes phenylephrine D010656|http://purl.obolibrary.org/obo/CHEBI_8093
T20 846-849 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T21 1020-1022 ChemicalEntity denotes CO D002248
T22 1085-1094 ChemicalEntity denotes ephedrine D004809
T23 1124-1127 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T24 1177-1179 ChemicalEntity denotes CO D002248
T25 1276-1289 ChemicalEntity denotes phenylephrine D010656|http://purl.obolibrary.org/obo/CHEBI_8093
T27 1375-1384 ChemicalEntity denotes ephedrine D004809
T28 1458-1460 ChemicalEntity denotes CO D002248

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 430-438 OrganismTaxon denotes patients
T2 481-489 OrganismTaxon denotes patients
T3 749-755 OrganismTaxon denotes HR, SV

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T28 1458-1460 ChemicalEntity denotes CO D002248
T27 1375-1384 ChemicalEntity denotes ephedrine D004809
T25 1276-1289 ChemicalEntity denotes phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093|D010656
T24 1177-1179 ChemicalEntity denotes CO D002248
T23 1124-1127 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T22 1085-1094 ChemicalEntity denotes ephedrine D004809
T21 1020-1022 ChemicalEntity denotes CO D002248
T20 846-849 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T18 831-844 ChemicalEntity denotes phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093|D010656
T17 761-763 ChemicalEntity denotes CO D002248
T16 744-747 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T15 619-621 ChemicalEntity denotes CO D002248
T14 578-581 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T13 555-558 ChemicalEntity denotes MAP http://purl.obolibrary.org/obo/CHEBI_6716
T12 499-508 ChemicalEntity denotes ephedrine D004809
T10 448-461 ChemicalEntity denotes phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093|D010656
T8 401-409 ChemicalEntity denotes propofol http://purl.obolibrary.org/obo/CHEBI_44915|D015742
T6 371-379 ChemicalEntity denotes fentanyl http://purl.obolibrary.org/obo/CHEBI_119915|D005283
T5 234-243 ChemicalEntity denotes ephedrine D004809
T3 216-229 ChemicalEntity denotes phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093|D010656
T2 22-31 ChemicalEntity denotes ephedrine D004809
T1 0-13 ChemicalEntity denotes Phenylephrine http://purl.obolibrary.org/obo/CHEBI_8093
T17056 1301-1312 DiseaseOrPhenotypicFeature denotes hypotension D007022
T4 583-589 DiseaseOrPhenotypicFeature denotes stroke D020521
T59031 312-323 DiseaseOrPhenotypicFeature denotes hypotension D007022
T43545 177-188 DiseaseOrPhenotypicFeature denotes hypotension D007022
T33886 94-105 DiseaseOrPhenotypicFeature denotes hypotension D007022
T87051 749-755 OrganismTaxon denotes HR, SV
T17378 481-489 OrganismTaxon denotes patients
T48953 430-438 OrganismTaxon denotes patients

Allie

Id Subject Object Predicate Lexical cue
SS1_19957053_5_0 531-553 expanded denotes mean arterial pressure
SS2_19957053_5_0 555-558 abbr denotes MAP
SS1_19957053_6_0 561-571 expanded denotes Heart rate
SS2_19957053_6_0 573-575 abbr denotes HR
SS1_19957053_6_1 583-596 expanded denotes stroke volume
SS2_19957053_6_1 598-600 abbr denotes SV
SS1_19957053_6_2 603-617 expanded denotes cardiac output
SS2_19957053_6_2 619-621 abbr denotes CO
AE1_19957053_5_0 SS1_19957053_5_0 SS2_19957053_5_0 abbreviatedTo mean arterial pressure,MAP
AE1_19957053_6_0 SS1_19957053_6_0 SS2_19957053_6_0 abbreviatedTo Heart rate,HR
AE1_19957053_6_1 SS1_19957053_6_1 SS2_19957053_6_1 abbreviatedTo stroke volume,SV
AE1_19957053_6_2 SS1_19957053_6_2 SS2_19957053_6_2 abbreviatedTo cardiac output,CO