PubMed:1993703 JSONTXT

{"project":"sentences","denotations":[{"id":"T1","span":{"begin":0,"end":28},"obj":"Sentence"},{"id":"T2","span":{"begin":29,"end":181},"obj":"Sentence"},{"id":"T3","span":{"begin":182,"end":412},"obj":"Sentence"},{"id":"T4","span":{"begin":413,"end":558},"obj":"Sentence"},{"id":"T5","span":{"begin":559,"end":788},"obj":"Sentence"},{"id":"T6","span":{"begin":789,"end":947},"obj":"Sentence"},{"id":"T7","span":{"begin":948,"end":1102},"obj":"Sentence"},{"id":"T8","span":{"begin":1103,"end":1229},"obj":"Sentence"},{"id":"T9","span":{"begin":1230,"end":1359},"obj":"Sentence"},{"id":"T10","span":{"begin":1360,"end":1524},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":28},"obj":"Sentence"},{"id":"T2","span":{"begin":29,"end":181},"obj":"Sentence"},{"id":"T3","span":{"begin":182,"end":412},"obj":"Sentence"},{"id":"T4","span":{"begin":413,"end":558},"obj":"Sentence"},{"id":"T5","span":{"begin":559,"end":788},"obj":"Sentence"},{"id":"T6","span":{"begin":789,"end":947},"obj":"Sentence"},{"id":"T7","span":{"begin":948,"end":1102},"obj":"Sentence"},{"id":"T8","span":{"begin":1103,"end":1229},"obj":"Sentence"},{"id":"T9","span":{"begin":1230,"end":1359},"obj":"Sentence"},{"id":"T10","span":{"begin":1360,"end":1524},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T1","span":{"begin":287,"end":292},"obj":"http://purl.obolibrary.org/obo/MAT_0000097"},{"id":"T2","span":{"begin":1223,"end":1228},"obj":"http://purl.obolibrary.org/obo/MAT_0000097"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"Anatomy-MAT","denotations":[{"id":"T1","span":{"begin":287,"end":292},"obj":"Body_part"},{"id":"T2","span":{"begin":1223,"end":1228},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000097"},{"id":"A2","pred":"mat_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MAT_0000097"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"testtesttest","denotations":[{"id":"T1","span":{"begin":21,"end":27},"obj":"Body_part"},{"id":"T2","span":{"begin":254,"end":260},"obj":"Body_part"},{"id":"T3","span":{"begin":287,"end":292},"obj":"Body_part"},{"id":"T4","span":{"begin":1223,"end":1228},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":4,"end":11},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":237,"end":244},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":340,"end":343},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"3846"},{"id":"A2","pred":"db_id","subj":"T2","obj":"3846"},{"id":"A3","pred":"db_id","subj":"T3","obj":"10114"},{"id":"A4","pred":"db_id","subj":"T3","obj":"10116"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":287,"end":292},"obj":"Body_part"},{"id":"T2","span":{"begin":1223,"end":1228},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}

{"project":"Glycosmos15-CL","denotations":[{"id":"T1","span":{"begin":981,"end":986},"obj":"Cell"}],"attributes":[{"id":"A1","pred":"cl_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CL:0004124"}],"text":"The glycine cleavage system. Occurrence of two types of chicken H-protein mRNAs presumably formed by the alternative use of the polyadenylation consensus sequences in a single exon.\nSeveral cDNAs encoding H-protein, a constituent of the glycine cleavage system, were cloned from chicken liver cDNA libraries with an antibody raised against rat H-protein or with a nick-translated cDNA of an immunoreactive clone. The structure of the H-protein cDNA consisting of 910 base pairs was determined using clones with an apparent overlap in the nucleotide sequence. The cDNA encodes the precursor form of H-protein that is comprised of 39 amino acid residues for a mitochondrial presequence and 125 amino acid residues for the mature protein, following a 5' untranslated region of 13 base pairs. There are two genuine consensus sequences for the cleavage/polyadenylation of the precursor H-protein mRNA in the 3' untranslated region of the cDNA sequence. We showed by comparison with the delta-aminolevulinate synthase gene that only one copy of the H-protein cDNA occurs in the haploid genome of the chicken. Nevertheless, two types of H-protein mRNAs, which differ by the length of their 3' untranslated region, are produced in liver. The chicken H-protein gene extends over 8 kilobase pairs on the genome and includes 5 exons that encode the entire cDNA sequence. Two AATAAA motifs are coded in the last exon of this gene, suggesting that the differently size H-protein mRNAs are produced by the alternative use of these motifs."}