> top > docs > PubMed:19917135 > annotations

PubMed:19917135 JSONTXT

Annnotations TAB JSON ListView MergeView

PubTator4TogoVar

Id Subject Object Predicate Lexical cue proteinmutation
19917135_0 53-58 ProteinMutation denotes R175H rs28934576
19917135_1 1001-1006 ProteinMutation denotes R175H rs28934576
19917135_2 966-971 ProteinMutation denotes R175H rs28934576
19917135_3 826-831 ProteinMutation denotes R175H rs28934576
19917135_4 1339-1344 ProteinMutation denotes R175H rs28934576
19917135_5 1130-1135 ProteinMutation denotes R175H rs28934576
19917135_6 1558-1563 ProteinMutation denotes R175H rs28934576

sonoma

Id Subject Object Predicate Lexical cue
T0 0-8 POSREG denotes Elevated
T1 9-19 MPA denotes expression
T2 23-26 GENE denotes p53
T3 27-43 POSREG denotes gain-of-function
T4 53-58 VAR denotes R175H
T5 62-80 DISEASE denotes endometrial cancer
T6 91-99 POSREG denotes increase
T7 104-123 CPA denotes invasive phenotypes
T8 127-137 POSREG denotes activation
T9 145-166 PATHWAY denotes EGFR/PI3K/AKT pathway
T10 180-183 GENE denotes p53
T11 205-212 VAR denotes mutated
T12 238-251 DISEASE denotes human cancers
T13 272-276 NEGREG denotes loss
T14 280-306 MPA denotes tumor suppression function
T15 311-319 POSREG denotes exertion
T16 323-340 NEGREG denotes dominant-negative
T17 395-398 GENE denotes p53
T18 399-406 VAR denotes mutants
T19 411-415 POSREG denotes gain
T20 422-441 MPA denotes oncogenic functions
T21 443-459 POSREG denotes gain-of-function
T22 461-464 POSREG denotes GOF
T23 480-488 REG denotes regulate
T24 496-507 CPA denotes development
T25 512-523 CPA denotes progression
T26 534-552 DISEASE denotes endometrial cancer
T27 554-557 GENE denotes p53
T28 558-566 VAR denotes mutation
T29 581-591 REG denotes associated
T30 608-630 DISEASE denotes nonendometrioid cancer
T31 659-662 GENE denotes p53
T32 663-670 VAR denotes mutants
T33 671-682 REG denotes contributed
T34 686-704 DISEASE denotes endometrial cancer
T35 705-716 CPA denotes progression
T36 729-732 POSREG denotes GOF
T37 769-781 REG denotes relationship
T38 790-800 MPA denotes expression
T39 804-807 GENE denotes p53
T40 808-811 POSREG denotes GOF
T41 812-820 VAR denotes mutation
T42 822-831 VAR denotes p53-R175H
T43 837-855 CPA denotes invasive potential
T44 865-883 DISEASE denotes endometrial cancer
T45 925-938 POSREG denotes up-regulation
T46 943-958 NEGREG denotes down-regulation
T47 962-971 VAR denotes p53-R175H
T48 988-996 POSREG denotes inducing
T49 997-1006 VAR denotes p53-R175H
T50 1028-1039 NEGREG denotes suppressing
T51 1044-1047 GENE denotes p53
T52 1100-1106 POSREG denotes forced
T53 1107-1122 POSREG denotes over-expression
T54 1126-1135 VAR denotes p53-R175H
T55 1150-1158 POSREG denotes promoted
T56 1164-1173 CPA denotes migration
T57 1178-1186 CPA denotes invasion
T58 1192-1199 POSREG denotes induced
T59 1200-1210 POSREG denotes activation
T60 1218-1306 PATHWAY denotes epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway
T61 1320-1331 NEGREG denotes suppression
T62 1382-1391 NEGREG denotes inhibited
T63 1397-1406 CPA denotes migration
T64 1411-1419 CPA denotes invasion
T65 1425-1433 REG denotes resulted
T66 1437-1448 NEGREG denotes attenuation
T67 1452-1473 PATHWAY denotes EGFR/PI3K/AKT pathway
T68 1531-1539 POSREG denotes elevated
T69 1540-1550 MPA denotes expression
T70 1581-1597 POSREG denotes gain-of-function
T71 1598-1606 MPA denotes activity
T72 1610-1618 POSREG denotes activate
T73 1623-1644 PATHWAY denotes EGFR/PI3K/AKT pathway
T74 1658-1668 REG denotes contribute
T75 1676-1694 CPA denotes invasive phenotype
T76 1698-1716 DISEASE denotes endometrial cancer
R7 T4 T8 CauseOf R175H,activation
R8 T5 T0 ThemeOf endometrial cancer,Elevated
R9 T5 T1 ThemeOf endometrial cancer,expression
R10 T5 T3 ThemeOf endometrial cancer,gain-of-function
R11 T5 T4 ThemeOf endometrial cancer,R175H
R12 T8 T6 CauseOf activation,increase
R13 T7 T6 ThemeOf invasive phenotypes,increase
R14 T9 T8 ThemeOf EGFR/PI3K/AKT pathway,activation
R15 T10 T11 ThemeOf p53,mutated
R16 T12 T11 ThemeOf human cancers,mutated
R17 T11 T13 CauseOf mutated,loss
R18 T11 T15 CauseOf mutated,exertion
R19 T14 T13 ThemeOf tumor suppression function,loss
R20 T17 T18 ThemeOf p53,mutants
R21 T18 T13 CauseOf mutants,loss
R22 T18 T15 CauseOf mutants,exertion
R23 T18 T19 CauseOf mutants,gain
R24 T18 T21 CauseOf mutants,gain-of-function
R25 T18 T22 CauseOf mutants,GOF
R50 T42 T41 ThemeOf p53-R175H,mutation
R51 T44 T37 ThemeOf endometrial cancer,relationship
R52 T44 T38 ThemeOf endometrial cancer,expression
R53 T44 T40 ThemeOf endometrial cancer,GOF
R54 T44 T43 ThemeOf endometrial cancer,invasive potential
R55 T44 T45 ThemeOf endometrial cancer,up-regulation
R56 T47 T46 ThemeOf p53-R175H,down-regulation
R57 T50 T48 CauseOf suppressing,inducing
R58 T51 T50 ThemeOf p53,suppressing
R59 T52 T55 CauseOf forced,promoted
R60 T52 T58 CauseOf forced,induced
R61 T53 T55 CauseOf over-expression,promoted
R0 T0 T3 CauseOf Elevated,gain-of-function
R1 T0 T6 CauseOf Elevated,increase
R2 T0 T8 CauseOf Elevated,activation
R3 T1 T0 ThemeOf expression,Elevated
R4 T2 T1 ThemeOf p53,expression
R5 T4 T3 CauseOf R175H,gain-of-function
R6 T4 T6 CauseOf R175H,increase
R26 T18 T23 CauseOf mutants,regulate
R27 T20 T19 ThemeOf oncogenic functions,gain
R28 T24 T23 ThemeOf development,regulate
R29 T25 T23 ThemeOf progression,regulate
R30 T26 T29 ThemeOf endometrial cancer,associated
R31 T27 T28 ThemeOf p53,mutation
R32 T28 T29 CauseOf mutation,associated
R33 T30 T29 ThemeOf nonendometrioid cancer,associated
R34 T31 T32 ThemeOf p53,mutants
R35 T32 T33 CauseOf mutants,contributed
R36 T32 T35 CauseOf mutants,progression
R37 T32 T36 CauseOf mutants,GOF
R38 T34 T33 ThemeOf endometrial cancer,contributed
R39 T34 T35 ThemeOf endometrial cancer,progression
R40 T34 T36 ThemeOf endometrial cancer,GOF
R41 T35 T33 ThemeOf progression,contributed
R42 T35 T36 ThemeOf progression,GOF
R43 T38 T37 ThemeOf expression,relationship
R44 T38 T40 ThemeOf expression,GOF
R45 T39 T37 ThemeOf p53,relationship
R46 T39 T38 ThemeOf p53,expression
R47 T39 T41 ThemeOf p53,mutation
R48 T41 T40 CauseOf mutation,GOF
R49 T42 T38 ThemeOf p53-R175H,expression
R62 T53 T58 CauseOf over-expression,induced
R63 T54 T53 ThemeOf p53-R175H,over-expression
R64 T54 T58 CauseOf p53-R175H,induced
R65 T56 T55 ThemeOf migration,promoted
R66 T57 T55 ThemeOf invasion,promoted
R67 T60 T58 ThemeOf epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway,induced
R68 T60 T59 ThemeOf epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway,activation
R69 T61 T62 CauseOf suppression,inhibited
R70 T61 T65 CauseOf suppression,resulted
R71 T61 T66 CauseOf suppression,attenuation
R72 T63 T62 ThemeOf migration,inhibited
R73 T64 T62 ThemeOf invasion,inhibited
R74 T67 T66 ThemeOf EGFR/PI3K/AKT pathway,attenuation
R75 T68 T70 CauseOf elevated,gain-of-function
R76 T68 T72 CauseOf elevated,activate
R77 T68 T74 CauseOf elevated,contribute
R78 T69 T68 ThemeOf expression,elevated
R79 T73 T72 ThemeOf EGFR/PI3K/AKT pathway,activate
R80 T75 T74 ThemeOf invasive phenotype,contribute
R81 T76 T74 ThemeOf endometrial cancer,contribute
R82 T76 T75 ThemeOf endometrial cancer,invasive phenotype

DisGeNET

Id Subject Object Predicate Lexical cue
T0 395-398 gene:7157 denotes p53
T1 489-495 disease:C1306459 denotes cancer
T2 395-398 gene:7157 denotes p53
T3 489-495 disease:C0006826 denotes cancer
T4 554-557 gene:7157 denotes p53
T5 624-630 disease:C1306459 denotes cancer
T6 554-557 gene:7157 denotes p53
T7 624-630 disease:C0006826 denotes cancer
T8 1628-1632 gene:5293 denotes PI3K
T9 1698-1716 disease:C0476089 denotes endometrial cancer
T10 1623-1627 gene:1956 denotes EGFR
T11 1698-1716 disease:C0476089 denotes endometrial cancer
T12 1623-1627 gene:1956 denotes EGFR
T13 1698-1716 disease:C1883486 denotes endometrial cancer
T14 1628-1632 gene:5294 denotes PI3K
T15 1698-1716 disease:C0007103 denotes endometrial cancer
T16 1628-1632 gene:5294 denotes PI3K
T17 1698-1716 disease:C0476089 denotes endometrial cancer
T18 1628-1632 gene:5294 denotes PI3K
T19 1698-1716 disease:C1883486 denotes endometrial cancer
T20 1628-1632 gene:5293 denotes PI3K
T21 1698-1716 disease:C0007103 denotes endometrial cancer
T22 1623-1627 gene:1956 denotes EGFR
T23 1698-1716 disease:C0007103 denotes endometrial cancer
T24 1628-1632 gene:5293 denotes PI3K
T25 1698-1716 disease:C1883486 denotes endometrial cancer
T26 1628-1632 gene:5290 denotes PI3K
T27 1698-1716 disease:C0007103 denotes endometrial cancer
T28 1628-1632 gene:5290 denotes PI3K
T29 1698-1716 disease:C0476089 denotes endometrial cancer
T30 1628-1632 gene:5290 denotes PI3K
T31 1698-1716 disease:C1883486 denotes endometrial cancer
T32 1628-1632 gene:5291 denotes PI3K
T33 1698-1716 disease:C0007103 denotes endometrial cancer
T34 1628-1632 gene:5291 denotes PI3K
T35 1698-1716 disease:C0476089 denotes endometrial cancer
T36 1628-1632 gene:5291 denotes PI3K
T37 1698-1716 disease:C1883486 denotes endometrial cancer
T38 1633-1636 gene:207 denotes AKT
T39 1698-1716 disease:C0007103 denotes endometrial cancer
T40 1633-1636 gene:207 denotes AKT
T41 1698-1716 disease:C0476089 denotes endometrial cancer
T42 1633-1636 gene:207 denotes AKT
T43 1698-1716 disease:C1883486 denotes endometrial cancer
R1 T0 T1 associated_with p53,cancer
R2 T2 T3 associated_with p53,cancer
R3 T4 T5 associated_with p53,cancer
R4 T6 T7 associated_with p53,cancer
R5 T8 T9 associated_with PI3K,endometrial cancer
R6 T10 T11 associated_with EGFR,endometrial cancer
R7 T12 T13 associated_with EGFR,endometrial cancer
R8 T14 T15 associated_with PI3K,endometrial cancer
R9 T16 T17 associated_with PI3K,endometrial cancer
R10 T18 T19 associated_with PI3K,endometrial cancer
R11 T20 T21 associated_with PI3K,endometrial cancer
R12 T22 T23 associated_with EGFR,endometrial cancer
R13 T24 T25 associated_with PI3K,endometrial cancer
R14 T26 T27 associated_with PI3K,endometrial cancer
R15 T28 T29 associated_with PI3K,endometrial cancer
R16 T30 T31 associated_with PI3K,endometrial cancer
R17 T32 T33 associated_with PI3K,endometrial cancer
R18 T34 T35 associated_with PI3K,endometrial cancer
R19 T36 T37 associated_with PI3K,endometrial cancer
R20 T38 T39 associated_with AKT,endometrial cancer
R21 T40 T41 associated_with AKT,endometrial cancer
R22 T42 T43 associated_with AKT,endometrial cancer

DisGeNET5_variant_disease

Id Subject Object Predicate Lexical cue
19917135-0#53#58#geners760101437 53-58 geners760101437 denotes R175H
19917135-0#53#58#geners28934578 53-58 geners28934578 denotes R175H
19917135-0#53#58#geners573154688 53-58 geners573154688 denotes R175H
19917135-0#62#80#diseaseC0007103 62-80 diseaseC0007103 denotes endometrial cancer
19917135-0#62#80#diseaseC0476089 62-80 diseaseC0476089 denotes endometrial cancer
19917135-0#62#80#diseaseC1883486 62-80 diseaseC1883486 denotes endometrial cancer
19917135-0#62#80#diseaseC0007103 62-80 diseaseC0007103 denotes endometrial cancer
19917135-0#62#80#diseaseC0476089 62-80 diseaseC0476089 denotes endometrial cancer
19917135-0#62#80#diseaseC1883486 62-80 diseaseC1883486 denotes endometrial cancer
19917135-0#62#80#diseaseC0007103 62-80 diseaseC0007103 denotes endometrial cancer
19917135-0#62#80#diseaseC0476089 62-80 diseaseC0476089 denotes endometrial cancer
19917135-0#62#80#diseaseC1883486 62-80 diseaseC1883486 denotes endometrial cancer
53#58#geners76010143762#80#diseaseC0007103 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC0476089 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC1883486 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC0007103 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC0476089 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC1883486 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC0007103 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC0476089 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners76010143762#80#diseaseC1883486 19917135-0#53#58#geners760101437 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0007103 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0476089 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC1883486 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0007103 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0476089 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC1883486 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0007103 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC0476089 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners2893457862#80#diseaseC1883486 19917135-0#53#58#geners28934578 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0007103 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0476089 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC1883486 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0007103 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0476089 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC1883486 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0007103 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0007103 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC0476089 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC0476089 associated_with R175H,endometrial cancer
53#58#geners57315468862#80#diseaseC1883486 19917135-0#53#58#geners573154688 19917135-0#62#80#diseaseC1883486 associated_with R175H,endometrial cancer

kaiyin_test

Id Subject Object Predicate Lexical cue
T1 554-557 Gene denotes p53
T2 558-566 Var denotes mutation
T3 581-591 Reg denotes associated
T4 597-630 Disease denotes aggressive nonendometrioid cancer
T22 898-904 Reg denotes tested
T20 925-938 PosReg denotes up-regulation
T21 943-958 NegReg denotes down-regulation
T18 988-996 Reg denotes inducing
T19 997-1024 Protein denotes p53-R175H expression vector
T16 1028-1039 NegReg denotes suppressing
T17 1044-1052 Gene denotes p53 gene
T23 1107-1122 PosReg denotes over-expression
T24 1126-1135 Protein denotes p53-R175H
T5 1126-1129 Gene denotes p53
T6 1130-1135 Var denotes R175H
T25 1150-1158 PosReg denotes promoted
T7 1150-1158 PosReg denotes promoted
T26 1159-1186 CPA denotes cell migration and invasion
T8 1159-1173 CPA denotes cell migration
T9 1178-1186 CPA denotes invasion
T10 1200-1210 PosReg denotes activation
T27 1200-1210 PosReg denotes activation
T11 1218-1306 Pathway denotes epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway
T28 1218-1306 Pathway denotes epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway
T29 1320-1331 NegReg denotes suppression
T30 1335-1344 Protein denotes p53-R175H
T31 1350-1367 Gene denotes short hairpin RNA
T32 1382-1391 NegReg denotes inhibited
T33 1392-1419 CPA denotes cell migration and invasion
T34 1437-1448 NegReg denotes attenuation
T35 1452-1474 Pathway denotes EGFR/PI3K/AKT pathway.
T37 1531-1539 PosReg denotes elevated
T38 1540-1550 MPA denotes expression
T12 1554-1557 Gene denotes p53
T13 1558-1563 Var denotes R175H
T39 1581-1585 PosReg denotes gain
T40 1589-1606 MPA denotes function activity
T41 1610-1618 PosReg denotes activate
T42 1623-1644 Pathway denotes EGFR/PI3K/AKT pathway
T43 1658-1668 Reg denotes contribute
T44 1698-1716 Disease denotes endometrial cancer
R11 T19 T18 ThemeOf p53-R175H expression vector,inducing
R12 T19 T22 CauseOf p53-R175H expression vector,tested
R13 T20 T22 ThemeOf up-regulation,tested
R14 T21 T22 ThemeOf down-regulation,tested
R15 T17 T16 ThemeOf p53 gene,suppressing
R16 T17 T22 CauseOf p53 gene,tested
R19 T24 T23 ThemeOf p53-R175H,over-expression
R20 T24 T25 CauseOf p53-R175H,promoted
R21 T26 T25 ThemeOf cell migration and invasion,promoted
R22 T24 T27 CauseOf p53-R175H,activation
R23 T28 T27 ThemeOf epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway,activation
R24 T31 T29 CauseOf short hairpin RNA,suppression
R25 T30 T29 ThemeOf p53-R175H,suppression
R26 T30 T32 CauseOf p53-R175H,inhibited
R27 T33 T32 ThemeOf cell migration and invasion,inhibited
R28 T30 T34 CauseOf p53-R175H,attenuation
R29 T35 T34 ThemeOf EGFR/PI3K/AKT pathway.,attenuation
R31 T38 T37 ThemeOf expression,elevated
R33 T40 T39 ThemeOf function activity,gain
R35 T42 T41 ThemeOf EGFR/PI3K/AKT pathway,activate
R37 T44 T43 ThemeOf endometrial cancer,contribute
R38 T12 T13 ThemeOf p53,R175H
R39 T13 T37 CauseOf R175H,elevated
R40 T1 T2 ThemeOf p53,mutation
R41 T2 T3 CauseOf mutation,associated
R42 T4 T3 ThemeOf aggressive nonendometrioid cancer,associated
R43 T13 T39 CauseOf R175H,gain
R44 T39 T41 CauseOf gain,activate
R45 T41 T43 CauseOf activate,contribute

name_no

Id Subject Object Predicate Lexical cue
T1 554-557 Gene denotes p53
T2 558-566 Var denotes mutation
T3 581-591 Reg denotes associated
T4 597-630 Disease denotes aggressive nonendometrioid cancer
T22 898-904 Reg denotes tested
T20 925-938 PosReg denotes up-regulation
T21 943-958 NegReg denotes down-regulation
T18 988-996 Reg denotes inducing
T19 997-1024 Protein denotes p53-R175H expression vector
T16 1028-1039 NegReg denotes suppressing
T17 1044-1052 Gene denotes p53 gene
T23 1107-1122 PosReg denotes over-expression
T24 1126-1135 Protein denotes p53-R175H
T5 1126-1129 Gene denotes p53
T6 1130-1135 Var denotes R175H
T25 1150-1158 PosReg denotes promoted
T7 1150-1158 PosReg denotes promoted
T26 1159-1186 CPA denotes cell migration and invasion
T8 1159-1173 CPA denotes cell migration
T9 1178-1186 CPA denotes invasion
T10 1200-1210 PosReg denotes activation
T27 1200-1210 PosReg denotes activation
T11 1218-1306 Pathway denotes epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway
T28 1218-1306 Pathway denotes epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway
T29 1320-1331 NegReg denotes suppression
T30 1335-1344 Protein denotes p53-R175H
T31 1350-1367 Gene denotes short hairpin RNA
T32 1382-1391 NegReg denotes inhibited
T33 1392-1419 CPA denotes cell migration and invasion
T34 1437-1448 NegReg denotes attenuation
T35 1452-1474 Pathway denotes EGFR/PI3K/AKT pathway.
T37 1531-1539 PosReg denotes elevated
T38 1540-1550 MPA denotes expression
T12 1554-1557 Gene denotes p53
T13 1558-1563 Var denotes R175H
T39 1581-1585 PosReg denotes gain
T40 1589-1606 MPA denotes function activity
T41 1610-1618 PosReg denotes activate
T42 1623-1644 Pathway denotes EGFR/PI3K/AKT pathway
T43 1658-1668 Reg denotes contribute
T44 1698-1716 Disease denotes endometrial cancer
R11 T19 T18 ThemeOf p53-R175H expression vector,inducing
R12 T19 T22 CauseOf p53-R175H expression vector,tested
R13 T20 T22 ThemeOf up-regulation,tested
R14 T21 T22 ThemeOf down-regulation,tested
R15 T17 T16 ThemeOf p53 gene,suppressing
R16 T17 T22 CauseOf p53 gene,tested
R19 T24 T23 ThemeOf p53-R175H,over-expression
R20 T24 T25 CauseOf p53-R175H,promoted
R21 T26 T25 ThemeOf cell migration and invasion,promoted
R22 T24 T27 CauseOf p53-R175H,activation
R23 T28 T27 ThemeOf epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/AKT pathway,activation
R24 T31 T29 CauseOf short hairpin RNA,suppression
R25 T30 T29 ThemeOf p53-R175H,suppression
R26 T30 T32 CauseOf p53-R175H,inhibited
R27 T33 T32 ThemeOf cell migration and invasion,inhibited
R28 T30 T34 CauseOf p53-R175H,attenuation
R29 T35 T34 ThemeOf EGFR/PI3K/AKT pathway.,attenuation
R31 T38 T37 ThemeOf expression,elevated
R33 T40 T39 ThemeOf function activity,gain
R35 T42 T41 ThemeOf EGFR/PI3K/AKT pathway,activate
R37 T44 T43 ThemeOf endometrial cancer,contribute
R38 T12 T13 ThemeOf p53,R175H
R39 T13 T37 CauseOf R175H,elevated
R40 T1 T2 ThemeOf p53,mutation
R41 T2 T3 CauseOf mutation,associated
R42 T4 T3 ThemeOf aggressive nonendometrioid cancer,associated
R43 T13 T39 CauseOf R175H,gain
R44 T39 T41 CauseOf gain,activate
R45 T41 T43 CauseOf activate,contribute