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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-74 Sentence denotes hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type.
T2 75-204 Sentence denotes Human 8-oxoguanine DNA glycosylase 1 (hOGG1) has a major role in the repair of 8-hydroxyguanine, a major promutagenic DNA lesion.
T3 205-400 Sentence denotes The genetic polymorphism rs1052133, which leads to substitution of the amino acid at codon 326 from Ser to Cys, shows functional differences, namely a decrease in enzyme activity in hOGG1-Cys326.
T4 401-589 Sentence denotes Although several studies have investigated the association between rs1052133 and lung cancer susceptibility, the effect of this locus on lung cancer according to histology remains unclear.
T5 590-763 Sentence denotes We therefore conducted a case-control study with 515 incident lung cancer cases and 1030 age- and sex-matched controls without cancer, and further conducted a meta-analysis.
T6 764-968 Sentence denotes In overall analysis, the homozygous Cys/Cys genotype showed a significant association with lung cancer compared to Ser allele carrier status (odds ratio (OR)=1.31, 95% confidence interval (CI)=1.02-1.69).
T7 969-1204 Sentence denotes By histology-based analysis, the Cys/Cys genotype showed a significantly positive association with small-cell carcinoma (OR=2.40, 95% CI=1.32-4.49) and marginally significant association with adenocarcinoma (OR=1.32, 95% CI=0.98-1.77).
T8 1205-1424 Sentence denotes A meta-analysis of previous and our present study revealed that this polymorphism is positively associated with adenocarcinoma, although suggestive associations were also found for squamous- and small-cell lung cancers.
T9 1425-1513 Sentence denotes These results indicate that rs1052133 contributes to the risk of adenocarcinoma of lung.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 75-80 OrganismTaxon denotes Human NCBItxid:9606
T2 290-295 OrganismTaxon denotes codon NCBItxid:79338

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
6709 0-5 GeneOrGeneProduct denotes hOGG1 NCBIGene:4968
6710 6-15 SequenceVariant denotes Ser326Cys DBSNP:rs1052133
6711 41-52 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
6712 75-80 OrganismTaxon denotes Human NCBITaxon:9606
6713 81-111 GeneOrGeneProduct denotes 8-oxoguanine DNA glycosylase 1 NCBIGene:4968
6714 113-118 GeneOrGeneProduct denotes hOGG1 NCBIGene:4968
6715 154-170 ChemicalEntity denotes 8-hydroxyguanine MESH:C024829
6716 230-239 SequenceVariant denotes rs1052133 DBSNP:rs1052133
6717 296-315 SequenceVariant denotes 326 from Ser to Cys DBSNP:rs1052133
6718 387-392 GeneOrGeneProduct denotes hOGG1 NCBIGene:4968
6719 393-399 SequenceVariant denotes Cys326 DBSNP:rs1052133
6720 468-477 SequenceVariant denotes rs1052133 DBSNP:rs1052133
6721 482-493 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
6722 538-549 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
6723 652-663 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
6724 717-723 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
6725 855-866 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
6726 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma MESH:D018288
6727 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma MESH:D000230
6728 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma MESH:D000230
6729 1386-1423 DiseaseOrPhenotypicFeature denotes squamous- and small-cell lung cancers MESH:D002289|MESH:D055752
6730 1453-1462 SequenceVariant denotes rs1052133 DBSNP:rs1052133
6731 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung MESH:D000077192

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 41-52 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T2 46-52 DiseaseOrPhenotypicFeature denotes cancer 0004992
T3 482-493 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T4 487-493 DiseaseOrPhenotypicFeature denotes cancer 0004992
T5 538-549 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T6 543-549 DiseaseOrPhenotypicFeature denotes cancer 0004992
T7 652-663 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T8 657-663 DiseaseOrPhenotypicFeature denotes cancer 0004992
T9 717-723 DiseaseOrPhenotypicFeature denotes cancer 0004992
T10 855-866 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T11 860-866 DiseaseOrPhenotypicFeature denotes cancer 0004992
T12 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma 0000402
T13 1079-1088 DiseaseOrPhenotypicFeature denotes carcinoma 0004993
T14 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma 0004970
T15 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma 0004970
T16 1411-1423 DiseaseOrPhenotypicFeature denotes lung cancers 0008903
T17 1490-1504 DiseaseOrPhenotypicFeature denotes adenocarcinoma 0004970

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 6-15 SequenceVariant denotes Ser326Cys
T2 230-239 SequenceVariant denotes rs1052133
T3 468-477 SequenceVariant denotes rs1052133
T4 1453-1462 SequenceVariant denotes rs1052133

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-5 GeneOrGeneProduct denotes hOGG1
T2 41-45 GeneOrGeneProduct denotes lung
T3 81-111 GeneOrGeneProduct denotes 8-oxoguanine DNA glycosylase 1
T4 113-118 GeneOrGeneProduct denotes hOGG1
T5 120-125 GeneOrGeneProduct denotes has a
T6 126-131 GeneOrGeneProduct denotes major
T7 174-179 GeneOrGeneProduct denotes major
T8 197-203 GeneOrGeneProduct denotes lesion
T9 276-286 GeneOrGeneProduct denotes amino acid
T10 305-308 GeneOrGeneProduct denotes Ser
T11 312-315 GeneOrGeneProduct denotes Cys
T12 368-374 GeneOrGeneProduct denotes enzyme
T13 375-383 GeneOrGeneProduct denotes activity
T14 387-392 GeneOrGeneProduct denotes hOGG1
T15 482-486 GeneOrGeneProduct denotes lung
T16 538-542 GeneOrGeneProduct denotes lung
T17 581-588 GeneOrGeneProduct denotes unclear
T18 615-619 GeneOrGeneProduct denotes case
T19 652-656 GeneOrGeneProduct denotes lung
T20 664-669 GeneOrGeneProduct denotes cases
T21 749-753 GeneOrGeneProduct denotes meta
T22 800-803 GeneOrGeneProduct denotes Cys
T23 804-807 GeneOrGeneProduct denotes Cys
T24 855-859 GeneOrGeneProduct denotes lung
T25 879-882 GeneOrGeneProduct denotes Ser
T26 890-897 GeneOrGeneProduct denotes carrier
T27 982-987 GeneOrGeneProduct denotes based
T28 1002-1005 GeneOrGeneProduct denotes Cys
T29 1006-1009 GeneOrGeneProduct denotes Cys
T30 1068-1073 GeneOrGeneProduct denotes small
T31 1074-1078 GeneOrGeneProduct denotes cell
T32 1121-1131 GeneOrGeneProduct denotes marginally
T33 1207-1211 GeneOrGeneProduct denotes meta
T34 1400-1405 GeneOrGeneProduct denotes small
T35 1406-1410 GeneOrGeneProduct denotes cell
T36 1411-1415 GeneOrGeneProduct denotes lung
T37 1508-1512 GeneOrGeneProduct denotes lung

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-5 GeneOrGeneProduct denotes hOGG1
T2 81-111 GeneOrGeneProduct denotes 8-oxoguanine DNA glycosylase 1
T3 113-118 GeneOrGeneProduct denotes hOGG1
T4 126-131 GeneOrGeneProduct denotes major
T5 174-179 GeneOrGeneProduct denotes major
T6 276-286 GeneOrGeneProduct denotes amino acid
T7 368-374 GeneOrGeneProduct denotes enzyme
T8 387-392 GeneOrGeneProduct denotes hOGG1
T9 581-588 GeneOrGeneProduct denotes unclear
T10 890-897 GeneOrGeneProduct denotes carrier
T11 1068-1073 GeneOrGeneProduct denotes small
T12 1074-1078 GeneOrGeneProduct denotes cell
T13 1400-1405 GeneOrGeneProduct denotes small
T14 1406-1410 GeneOrGeneProduct denotes cell

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 41-52 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T2 482-493 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T3 538-549 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T4 652-663 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T5 717-723 DiseaseOrPhenotypicFeature denotes cancer D009369
T6 855-866 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T7 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma D018288
T8 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T9 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T10 1400-1423 DiseaseOrPhenotypicFeature denotes small-cell lung cancers D055752
T11 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung D000077192

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-5 GeneOrGeneProduct denotes hOGG1
T2 81-111 GeneOrGeneProduct denotes 8-oxoguanine DNA glycosylase 1
T3 113-118 GeneOrGeneProduct denotes hOGG1
T4 387-392 GeneOrGeneProduct denotes hOGG1

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 41-52 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T3 482-493 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T5 538-549 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T7 652-663 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T9 855-866 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T11 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma 0000402
T12 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma 0004970
T13 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma 0004970
T14 1400-1423 DiseaseOrPhenotypicFeature denotes small-cell lung cancers 0008433
T15 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung 0005061

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 41-52 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T2 482-493 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T3 538-549 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T4 652-663 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T5 717-723 DiseaseOrPhenotypicFeature denotes cancer D009369
T6 855-866 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T7 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma D018288
T8 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T9 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T10 1400-1423 DiseaseOrPhenotypicFeature denotes small-cell lung cancers D055752
T11 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung D000077192

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 41-52 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T2 482-493 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T3 538-549 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T4 652-663 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T5 717-723 DiseaseOrPhenotypicFeature denotes cancer D009369
T6 855-866 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T7 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma D018288
T8 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T9 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T10 1400-1423 DiseaseOrPhenotypicFeature denotes small-cell lung cancers D055752
T11 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung D000077192

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 75-109 ChemicalEntity denotes Human 8-oxoguanine DNA glycosylase C479058
T2 154-170 ChemicalEntity denotes 8-hydroxyguanine C024829
T3 305-308 ChemicalEntity denotes Ser http://purl.obolibrary.org/obo/CHEBI_29999|http://purl.obolibrary.org/obo/CHEBI_17115
T5 312-315 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_15356
T8 800-803 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_15356
T11 804-807 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_15356
T14 879-882 ChemicalEntity denotes Ser http://purl.obolibrary.org/obo/CHEBI_29999|http://purl.obolibrary.org/obo/CHEBI_17115
T16 1002-1005 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_15356
T19 1006-1009 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_15356

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 75-80 OrganismTaxon denotes Human

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T19 1006-1009 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950
T16 1002-1005 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950
T14 879-882 ChemicalEntity denotes Ser http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999
T11 804-807 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950
T8 800-803 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950
T5 312-315 ChemicalEntity denotes Cys http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950
T3 305-308 ChemicalEntity denotes Ser http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999
T2 154-170 ChemicalEntity denotes 8-hydroxyguanine C024829
T1 75-109 ChemicalEntity denotes Human 8-oxoguanine DNA glycosylase C479058
T4 387-392 GeneOrGeneProduct denotes hOGG1
T43801 113-118 GeneOrGeneProduct denotes hOGG1
T78960 81-111 GeneOrGeneProduct denotes 8-oxoguanine DNA glycosylase 1
T88569 0-5 GeneOrGeneProduct denotes hOGG1
T15500 1490-1512 DiseaseOrPhenotypicFeature denotes adenocarcinoma of lung D000077192
T10 1400-1423 DiseaseOrPhenotypicFeature denotes small-cell lung cancers D055752
T9 1317-1331 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T90180 1161-1175 DiseaseOrPhenotypicFeature denotes adenocarcinoma D000230
T7 1068-1088 DiseaseOrPhenotypicFeature denotes small-cell carcinoma D018288
T6 855-866 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T29011 717-723 DiseaseOrPhenotypicFeature denotes cancer D009369
T85054 652-663 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T3357 538-549 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T41795 482-493 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T29757 41-52 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T88702 75-80 OrganismTaxon denotes Human
T72854 1453-1462 SequenceVariant denotes rs1052133
T27065 468-477 SequenceVariant denotes rs1052133
T92132 230-239 SequenceVariant denotes rs1052133
T53806 6-15 SequenceVariant denotes Ser326Cys

tmVarCorpus

Id Subject Object Predicate Lexical cue
T1 6-15 ProteinMutation:p|SUB|S|326|C denotes Ser326Cys
T2 230-239 SNP:rs1052133 denotes rs1052133
T3 468-477 SNP:rs1052133 denotes rs1052133
T4 1453-1462 SNP:rs1052133 denotes rs1052133

PubTator4TogoVar

Id Subject Object Predicate Lexical cue resolved_to
32 230-239 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
36 468-477 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
48 1453-1462 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606

PubTatorOnTogoVar

Id Subject Object Predicate Lexical cue resolved_to
32 230-239 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
36 468-477 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
48 1453-1462 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
T1 230-239 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
T2 468-477 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606
T3 1453-1462 SNP denotes rs1052133 tmVar:rs1052133;VariantGroup:0;CorrespondingGene:4968;RS#:1052133;CorrespondingSpecies:9606