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PubMed:19863441 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-159 Sentence denotes Infection with Mycobacterium tuberculosis Beijing genotype strains is associated with polymorphisms in SLC11A1/NRAMP1 in Indonesian patients with tuberculosis.
T2 160-282 Sentence denotes Differences in host immune genes may predispose to tuberculosis caused by particular Mycobacterium tuberculosis genotypes.
T3 283-542 Sentence denotes We examined this hypothesis in Indonesia by spoligotyping M. tuberculosis isolates recovered from 336 patients with pulmonary tuberculosis and typing the patients' SLC11A1 gene (formerly known as "NRAMP1"), which is involved in susceptibility to tuberculosis.
T4 543-814 Sentence denotes The M. tuberculosis Beijing genotype, which comprised 29.8% of all isolates, was strongly associated with 2 polymorphisms in SLC11A1: the D543N G allele (odds ratio [OR], 2.15; P=.005) and the 3' untranslated region (3'UTR) insertion/insertion genotype (OR, 2.5; P=.001).
T5 815-914 Sentence denotes This finding supports the hypothesis of coevolution of M. tuberculosis and the human immune system.
T1 0-159 Sentence denotes Infection with Mycobacterium tuberculosis Beijing genotype strains is associated with polymorphisms in SLC11A1/NRAMP1 in Indonesian patients with tuberculosis.
T2 160-282 Sentence denotes Differences in host immune genes may predispose to tuberculosis caused by particular Mycobacterium tuberculosis genotypes.
T3 283-542 Sentence denotes We examined this hypothesis in Indonesia by spoligotyping M. tuberculosis isolates recovered from 336 patients with pulmonary tuberculosis and typing the patients' SLC11A1 gene (formerly known as "NRAMP1"), which is involved in susceptibility to tuberculosis.
T4 543-814 Sentence denotes The M. tuberculosis Beijing genotype, which comprised 29.8% of all isolates, was strongly associated with 2 polymorphisms in SLC11A1: the D543N G allele (odds ratio [OR], 2.15; P=.005) and the 3' untranslated region (3'UTR) insertion/insertion genotype (OR, 2.5; P=.001).
T5 815-914 Sentence denotes This finding supports the hypothesis of coevolution of M. tuberculosis and the human immune system.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 103-110 gene:6556 denotes SLC11A1
T1 29-41 disease:C0041296 denotes tuberculosis
T2 103-110 gene:6556 denotes SLC11A1
T3 146-158 disease:C0041296 denotes tuberculosis
T4 111-117 gene:6556 denotes NRAMP1
T5 29-41 disease:C0041296 denotes tuberculosis
T6 111-117 gene:6556 denotes NRAMP1
T7 146-158 disease:C0041296 denotes tuberculosis
T8 447-454 gene:6556 denotes SLC11A1
T9 529-541 disease:C0041296 denotes tuberculosis
T10 447-454 gene:6556 denotes SLC11A1
T11 399-421 disease:C0041327 denotes pulmonary tuberculosis
T12 668-675 gene:6556 denotes SLC11A1
T13 550-562 disease:C0041296 denotes tuberculosis
R1 T0 T1 associated_with SLC11A1,tuberculosis
R2 T2 T3 associated_with SLC11A1,tuberculosis
R3 T4 T5 associated_with NRAMP1,tuberculosis
R4 T6 T7 associated_with NRAMP1,tuberculosis
R5 T8 T9 associated_with SLC11A1,tuberculosis
R6 T10 T11 associated_with SLC11A1,pulmonary tuberculosis
R7 T12 T13 associated_with SLC11A1,tuberculosis

DisGeNET5_variant_disease

Id Subject Object Predicate Lexical cue
19863441-3#138#143#geners17235409 681-686 geners17235409 denotes D543N
19863441-3#7#19#diseaseC0041296 550-562 diseaseC0041296 denotes tuberculosis
138#143#geners172354097#19#diseaseC0041296 19863441-3#138#143#geners17235409 19863441-3#7#19#diseaseC0041296 associated_with D543N,tuberculosis

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
19863441-0#103#110#gene6556 103-110 gene6556 denotes SLC11A1
19863441-0#111#117#gene6556 111-117 gene6556 denotes NRAMP1
19863441-0#29#41#diseaseC0041296 29-41 diseaseC0041296 denotes tuberculosis
19863441-0#146#158#diseaseC0041296 146-158 diseaseC0041296 denotes tuberculosis
19863441-2#164#171#gene6556 447-454 gene6556 denotes SLC11A1
19863441-2#197#203#gene6556 479-485 gene6556 denotes "NRAMP
19863441-2#116#138#diseaseC0041327 399-421 diseaseC0041327 denotes pulmonary tuberculosis
103#110#gene655629#41#diseaseC0041296 19863441-0#103#110#gene6556 19863441-0#29#41#diseaseC0041296 associated_with SLC11A1,tuberculosis
103#110#gene6556146#158#diseaseC0041296 19863441-0#103#110#gene6556 19863441-0#146#158#diseaseC0041296 associated_with SLC11A1,tuberculosis
111#117#gene655629#41#diseaseC0041296 19863441-0#111#117#gene6556 19863441-0#29#41#diseaseC0041296 associated_with NRAMP1,tuberculosis
111#117#gene6556146#158#diseaseC0041296 19863441-0#111#117#gene6556 19863441-0#146#158#diseaseC0041296 associated_with NRAMP1,tuberculosis
164#171#gene6556116#138#diseaseC0041327 19863441-2#164#171#gene6556 19863441-2#116#138#diseaseC0041327 associated_with SLC11A1,pulmonary tuberculosis
197#203#gene6556116#138#diseaseC0041327 19863441-2#197#203#gene6556 19863441-2#116#138#diseaseC0041327 associated_with """NRAMP",pulmonary tuberculosis