> top > docs > PubMed:1986254 > annotations
TextAE configuration unavailable!

PubMed:1986254 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 36-55 DNA denotes immunoglobulin gene
T2 78-110 DNA denotes B-cell-specific enhancer element
T3 118-150 DNA denotes B-cell-specific enhancer element
T4 177-206 DNA denotes E4 and the octamerlike motifs
T5 214-260 DNA denotes human immunoglobulin heavy-chain gene enhancer
T6 284-308 DNA denotes 67-bp MnlI-AluI fragment
T7 328-366 DNA denotes chloramphenicol acetyltransferase gene
T8 381-400 DNA denotes conalbumin promoter
T9 430-437 cell_type denotes B cells
T10 449-463 cell_line denotes Jurkat T cells
T11 467-477 cell_line denotes HeLa cells
T12 566-568 DNA denotes E6
T13 609-616 cell_type denotes B cells
T14 618-625 cell_type denotes T cells
T15 676-694 DNA denotes synthetic E6 motif
T16 706-729 protein denotes B-cell-specific complex
T17 777-784 cell_type denotes T cells
T18 789-799 cell_line denotes HeLa cells
T19 879-887 DNA denotes E6 motif
T20 916-921 cell_line denotes ARH77
T21 926-936 cell_line denotes Raji cells
T22 948-954 cell_line denotes Jurkat
T23 958-968 cell_line denotes HeLa cells
T24 985-1000 DNA denotes mutant E6 motif
T25 1096-1125 DNA denotes mouse Ig heavy-chain enhancer
T26 1140-1153 DNA denotes octamer motif
T27 1164-1196 DNA denotes B-cell-specific enhancer element
T28 1202-1216 DNA denotes human enhancer
T29 1229-1249 DNA denotes octamerlike sequence
T30 1289-1313 protein denotes octamer-binding proteins
T31 1405-1423 DNA denotes MnlI-AluI fragment
T32 1471-1490 DNA denotes conalbumin promoter
T33 1499-1505 cell_line denotes Jurkat
T34 1510-1520 cell_line denotes HeLa cells
T35 1585-1603 DNA denotes MnlI-AluI fragment
T36 1607-1617 cell_line denotes HeLa cells
T37 1629-1636 cell_type denotes B cells
T38 1731-1760 protein denotes positive and negative factors

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-111 Sentence denotes Positive and negative regulation of immunoglobulin gene expression by a novel B-cell-specific enhancer element.
S2 112-261 Sentence denotes A new B-cell-specific enhancer element has been identified 3' of E4 and the octamerlike motifs in the human immunoglobulin heavy-chain gene enhancer.
S3 262-478 Sentence denotes Tandem copies of this 67-bp MnlI-AluI fragment, when fused to the chloramphenicol acetyltransferase gene driven by the conalbumin promoter, stimulated transcription in B cells but not in Jurkat T cells or HeLa cells.
S4 479-641 Sentence denotes Footprinting analysis revealed that the identical sequence CCGAAACTGAAAAGG, designated E6, was protected by nuclear extracts from B cells, T cells, or HeLa cells.
S5 642-800 Sentence denotes Gel mobility shift assays using a synthetic E6 motif detected a B-cell-specific complex in addition to a ubiquitous band found also in T cells and HeLa cells.
S6 801-969 Sentence denotes In agreement with the results of gel retardation assays, tandem copies of the E6 motif stimulated transcription in ARH77 and Raji cells but not in Jurkat or HeLa cells.
S7 970-1067 Sentence denotes Furthermore, a mutant E6 motif lost both in vitro binding activity and in vivo enhancer activity.
S8 1068-1385 Sentence denotes In striking contrast to the mouse Ig heavy-chain enhancer, in which the octamer motif acts as a B-cell-specific enhancer element, the human enhancer contains an octamerlike sequence with one base substitution which bound octamer-binding proteins with only very low affinity and showed no enhancer activity of its own.
S9 1386-1521 Sentence denotes Interestingly, the MnlI-AluI fragment could suppress the basal-level activity of the conalbumin promoter in both Jurkat and HeLa cells.
S10 1522-1637 Sentence denotes Moreover, simian virus 40 enhancer activity was blocked by the MnlI-AluI fragment in HeLa cells but not in B cells.
S11 1638-1761 Sentence denotes Thus, the novel enhancer element identified in this study is probably a target site for both positive and negative factors.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 78-110 NP denotes B-cell-specific enhancer element
C1 70-110 NP denotes a novel B-cell-specific enhancer element
C4 118-150 NP denotes B-cell-specific enhancer element
C3 112-150 NP denotes A new B-cell-specific enhancer element
C5 210-260 NP denotes the human immunoglobulin heavy-chain gene enhancer
C6 279-308 NP denotes this 67-bp MnlI-AluI fragment
C7 377-400 NP denotes the conalbumin promoter
C8 430-437 NP denotes B cells
C10 456-463 NP denotes T cells
C9 449-463 NP denotes Jurkat T cells
C11 467-477 NP denotes HeLa cells
C12 515-553 NP denotes the identical sequence CCGAAACTGAAAAGG
C13 555-568 NP denotes designated E6
C14 609-616 NP denotes B cells
C15 618-625 NP denotes T cells
C16 630-640 NP denotes HeLa cells
C17 674-694 NP denotes a synthetic E6 motif
C18 777-784 NP denotes T cells
C19 789-799 NP denotes HeLa cells
C20 875-887 NP denotes the E6 motif
C21 948-954 NP denotes Jurkat
C22 958-968 NP denotes HeLa cells
C23 1092-1125 NP denotes the mouse Ig heavy-chain enhancer
C24 1130-1135 NP denotes which
C25 1162-1196 NP denotes a B-cell-specific enhancer element
C26 1198-1216 NP denotes the human enhancer
C27 1255-1276 NP denotes one base substitution
C28 1277-1282 NP denotes which
C29 1377-1380 NP denotes its
C30 1401-1423 NP denotes the MnlI-AluI fragment
C31 1467-1490 NP denotes the conalbumin promoter
C32 1499-1505 NP denotes Jurkat
C33 1510-1520 NP denotes HeLa cells
C34 1581-1603 NP denotes the MnlI-AluI fragment
C35 1607-1617 NP denotes HeLa cells
C36 1629-1636 NP denotes B cells
C37 1644-1695 NP denotes the novel enhancer element identified in this study
R1 C4 C2 coref-ident B-cell-specific enhancer element,B-cell-specific enhancer element
R2 C3 C1 coref-other A new B-cell-specific enhancer element,a novel B-cell-specific enhancer element
R3 C12 C13 coref-appos the identical sequence CCGAAACTGAAAAGG,designated E6
R4 C14 C8 coref-ident B cells,B cells
R5 C15 C10 coref-ident T cells,T cells
R6 C16 C11 coref-ident HeLa cells,HeLa cells
R7 C18 C15 coref-ident T cells,T cells
R8 C19 C16 coref-ident HeLa cells,HeLa cells
R9 C20 C17 coref-other the E6 motif,a synthetic E6 motif
R10 C21 C9 coref-other Jurkat,Jurkat T cells
R11 C22 C19 coref-ident HeLa cells,HeLa cells
R12 C24 C23 coref-relat which,the mouse Ig heavy-chain enhancer
R13 C25 C2 coref-ident a B-cell-specific enhancer element,B-cell-specific enhancer element
R14 C26 C5 coref-ident the human enhancer,the human immunoglobulin heavy-chain gene enhancer
R15 C28 C27 coref-relat which,one base substitution
R16 C29 C27 coref-pron its,one base substitution
R17 C30 C6 coref-other the MnlI-AluI fragment,this 67-bp MnlI-AluI fragment
R18 C31 C7 coref-ident the conalbumin promoter,the conalbumin promoter
R19 C32 C21 coref-other Jurkat,Jurkat
R20 C33 C22 coref-ident HeLa cells,HeLa cells
R21 C34 C30 coref-ident the MnlI-AluI fragment,the MnlI-AluI fragment
R22 C35 C33 coref-ident HeLa cells,HeLa cells
R23 C36 C8 coref-ident B cells,B cells
R24 C37 C1 coref-other the novel enhancer element identified in this study,a novel B-cell-specific enhancer element

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 36-55 DNA_family_or_group denotes immunoglobulin gene
T2 78-110 DNA_domain_or_region denotes B-cell-specific enhancer element
T3 118-150 DNA_domain_or_region denotes B-cell-specific enhancer element
T4 214-246 protein_subunit denotes human immunoglobulin heavy-chain
T5 284-308 DNA_domain_or_region denotes 67-bp MnlI-AluI fragment
T6 328-366 DNA_domain_or_region denotes chloramphenicol acetyltransferase gene
T7 381-400 DNA_domain_or_region denotes conalbumin promoter
T8 413-426 other_name denotes transcription
T9 430-437 cell_type denotes B cells
T10 449-463 cell_line denotes Jurkat T cells
T11 467-477 cell_line denotes HeLa cells
T12 479-500 other_name denotes Footprinting analysis
T13 538-553 polynucleotide denotes CCGAAACTGAAAAGG
T14 566-568 DNA_domain_or_region denotes E6
T15 587-603 cell_component denotes nuclear extracts
T16 609-616 cell_type denotes B cells
T17 618-625 cell_type denotes T cells
T18 642-667 other_name denotes Gel mobility shift assays
T19 676-694 DNA_domain_or_region denotes synthetic E6 motif
T20 706-729 protein_complex denotes B-cell-specific complex
T21 777-784 cell_type denotes T cells
T22 789-799 cell_line denotes HeLa cells
T23 834-856 other_name denotes gel retardation assays
T24 879-887 DNA_domain_or_region denotes E6 motif
T25 899-912 other_name denotes transcription
T26 916-921 cell_line denotes ARH77
T27 926-936 cell_line denotes Raji cells
T28 948-954 cell_line denotes Jurkat
T29 958-968 cell_line denotes HeLa cells
T30 985-1000 DNA_domain_or_region denotes mutant E6 motif
T31 1011-1036 other_name denotes in vitro binding activity
T32 1044-1066 other_name denotes vivo enhancer activity
T33 1096-1125 DNA_domain_or_region denotes mouse Ig heavy-chain enhancer
T34 1140-1153 DNA_domain_or_region denotes octamer motif
T35 1164-1196 DNA_domain_or_region denotes B-cell-specific enhancer element
T36 1202-1216 DNA_domain_or_region denotes human enhancer
T37 1229-1249 DNA_domain_or_region denotes octamerlike sequence
T38 1289-1313 protein_domain_or_region denotes octamer-binding proteins
T39 1356-1373 other_name denotes enhancer activity
T40 1405-1423 DNA_domain_or_region denotes MnlI-AluI fragment
T41 1471-1490 DNA_domain_or_region denotes conalbumin promoter
T42 1499-1505 cell_line denotes Jurkat
T43 1510-1520 cell_line denotes HeLa cells
T44 1532-1547 virus denotes simian virus 40
T45 1548-1565 other_name denotes enhancer activity
T46 1585-1603 DNA_domain_or_region denotes MnlI-AluI fragment
T47 1607-1617 cell_line denotes HeLa cells
T48 1629-1636 cell_type denotes B cells
T49 1731-1739 protein_molecule denotes positive
T50 1744-1760 protein_family_or_group denotes negative factors