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PubMed:19855377 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer.
TextSentencer_T2 115-459 Sentence denotes Triple-negative breast cancer, defined as that with negative expression of estrogen and progesterone receptors and cerbB2, accounted for 11% of invasive breast cancers in our study, drawn from an original cohort of 7048 women diagnosed with breast cancer from the files of the Department of Pathology, Singapore General Hospital, over 14 years.
TextSentencer_T3 460-631 Sentence denotes Women with triple-negative breast cancer were generally postmenopausal, with adverse pathological characteristics of high histological grade and frequent nodal metastases.
TextSentencer_T4 632-940 Sentence denotes Using a set of 61 invasive breast cancers earlier profiled into molecular subtypes with expression arrays, we defined specificity and sensitivity values for different immunohistochemical panels of basal keratins (CK5/6, CK14, CK17, 34 beta E12), CD117, EGFR, p63 and SMA in defining basal-like breast cancer.
TextSentencer_T5 941-1131 Sentence denotes Subsequent application of a tri-panel of CK14, EGFR and 34 beta E12 (specificity 100% and sensitivity 78%) to our group of 653 triple-negative breast cancers delineated 84% to be basal-like.
TextSentencer_T6 1132-1248 Sentence denotes Immunohistochemical expression of individual biological markers correlated with unfavorable pathological parameters.
TextSentencer_T7 1249-1465 Sentence denotes We conclude that triple-negative breast cancers in an Asian population harbor adverse pathobiological features, and an immunohistochemical surrogate panel can be reliably used to define basal-like cancers among them.
T1 0-114 Sentence denotes Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer.
T2 115-459 Sentence denotes Triple-negative breast cancer, defined as that with negative expression of estrogen and progesterone receptors and cerbB2, accounted for 11% of invasive breast cancers in our study, drawn from an original cohort of 7048 women diagnosed with breast cancer from the files of the Department of Pathology, Singapore General Hospital, over 14 years.
T3 460-631 Sentence denotes Women with triple-negative breast cancer were generally postmenopausal, with adverse pathological characteristics of high histological grade and frequent nodal metastases.
T4 632-940 Sentence denotes Using a set of 61 invasive breast cancers earlier profiled into molecular subtypes with expression arrays, we defined specificity and sensitivity values for different immunohistochemical panels of basal keratins (CK5/6, CK14, CK17, 34 beta E12), CD117, EGFR, p63 and SMA in defining basal-like breast cancer.
T5 941-1131 Sentence denotes Subsequent application of a tri-panel of CK14, EGFR and 34 beta E12 (specificity 100% and sensitivity 78%) to our group of 653 triple-negative breast cancers delineated 84% to be basal-like.
T6 1132-1248 Sentence denotes Immunohistochemical expression of individual biological markers correlated with unfavorable pathological parameters.
T7 1249-1465 Sentence denotes We conclude that triple-negative breast cancers in an Asian population harbor adverse pathobiological features, and an immunohistochemical surrogate panel can be reliably used to define basal-like cancers among them.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 982-986 gene:3861 denotes CK14
T1 1068-1098 disease:C3539878 denotes triple-negative breast cancers
T2 988-992 gene:1956 denotes EGFR
T3 1068-1098 disease:C3539878 denotes triple-negative breast cancers
R1 T0 T1 associated_with CK14,triple-negative breast cancers
R2 T2 T3 associated_with EGFR,triple-negative breast cancers

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
19855377-3#220#224#gene3861 852-856 gene3861 denotes CK14
19855377-3#267#270#gene6606 899-902 gene6606 denotes SMA
19855377-3#267#270#gene6607 899-902 gene6607 denotes SMA
19855377-3#294#307#diseaseC0006142 926-939 diseaseC0006142 denotes breast cancer
19855377-3#294#307#diseaseC0678222 926-939 diseaseC0678222 denotes breast cancer
19855377-3#294#307#diseaseC0006142 926-939 diseaseC0006142 denotes breast cancer
19855377-3#294#307#diseaseC0678222 926-939 diseaseC0678222 denotes breast cancer
19855377-3#294#307#diseaseC0006142 926-939 diseaseC0006142 denotes breast cancer
19855377-3#294#307#diseaseC0678222 926-939 diseaseC0678222 denotes breast cancer
19855377-4#47#51#gene1956 988-992 gene1956 denotes EGFR
19855377-4#127#157#diseaseC3539878 1068-1098 diseaseC3539878 denotes triple-negative breast cancers
220#224#gene3861294#307#diseaseC0006142 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0006142 associated_with CK14,breast cancer
220#224#gene3861294#307#diseaseC0678222 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0678222 associated_with CK14,breast cancer
220#224#gene3861294#307#diseaseC0006142 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0006142 associated_with CK14,breast cancer
220#224#gene3861294#307#diseaseC0678222 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0678222 associated_with CK14,breast cancer
220#224#gene3861294#307#diseaseC0006142 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0006142 associated_with CK14,breast cancer
220#224#gene3861294#307#diseaseC0678222 19855377-3#220#224#gene3861 19855377-3#294#307#diseaseC0678222 associated_with CK14,breast cancer
267#270#gene6606294#307#diseaseC0006142 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6606294#307#diseaseC0678222 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
267#270#gene6606294#307#diseaseC0006142 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6606294#307#diseaseC0678222 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
267#270#gene6606294#307#diseaseC0006142 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6606294#307#diseaseC0678222 19855377-3#267#270#gene6606 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0006142 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0678222 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0006142 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0678222 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0006142 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0006142 associated_with SMA,breast cancer
267#270#gene6607294#307#diseaseC0678222 19855377-3#267#270#gene6607 19855377-3#294#307#diseaseC0678222 associated_with SMA,breast cancer
47#51#gene1956127#157#diseaseC3539878 19855377-4#47#51#gene1956 19855377-4#127#157#diseaseC3539878 associated_with EGFR,triple-negative breast cancers

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 16-22 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T2 100-106 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 131-137 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 268-274 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 356-362 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T6 487-493 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T7 659-665 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T8 926-932 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T9 1084-1090 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T10 1282-1288 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T120 852-856 gene:3861 denotes CK14
T121 926-939 disease:C0006142 denotes breast cancer
T122 899-902 gene:6606 denotes SMA
R1 T120 T121 associated_with CK14,breast cancer
R2 T120 T121 associated_with CK14,breast cancer
R3 T122 T121 associated_with SMA,breast cancer
R4 T122 T121 associated_with SMA,breast cancer
R5 T122 T121 associated_with SMA,breast cancer
R6 T122 T121 associated_with SMA,breast cancer

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 16-22 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T2 100-106 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T3 131-137 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T4 268-274 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T5 356-362 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T6 487-493 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T7 659-665 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T8 926-932 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T9 1084-1090 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
PD-UBERON-AE-B_T10 1282-1288 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast