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PubMed:1967259 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 5-11 gene:6737 denotes Ro(SSA
T1 78-106 disease:C0024141 denotes systemic lupus erythematosus
R1 T0 T1 associated_with Ro(SSA,systemic lupus erythematosus

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-27 protein denotes Anti-Ro(SSA) autoantibodies
T2 48-74 DNA denotes T cell receptor beta genes
T3 237-251 protein denotes autoantibodies
T4 274-295 protein denotes HLA class II antigens
T5 300-314 protein denotes autoantibodies
T6 322-340 protein denotes ribonucleoproteins
T7 341-348 protein denotes Ro(SSA)
T8 353-360 protein denotes La(SSB)
T9 407-429 protein denotes HLA class II molecules
T10 449-465 protein denotes T cell receptors
T11 467-471 protein denotes TCRs
T12 497-505 DNA denotes TCR gene
T13 540-563 protein denotes anti-Ro(SSA) antibodies
T14 575-616 DNA denotes restriction fragment length polymorphisms
T15 618-623 DNA denotes RFLPs
T16 657-685 DNA denotes TCR constant region C beta 1
T17 707-720 DNA denotes C beta 2 gene
T18 815-829 DNA denotes TCR beta locus
T19 836-845 DNA denotes RFLP pair
T20 877-884 protein denotes Ro(SSA)
T21 910-917 protein denotes Ro(SSA)
T22 944-951 protein denotes La(SSB)
T23 952-963 protein denotes precipitins
T24 1007-1018 protein denotes precipitins
T25 1117-1122 DNA denotes RFLPs
T26 1200-1209 DNA denotes TCR genes
T27 1259-1282 protein denotes anti-Ro(SSA) antibodies
T28 1324-1329 DNA denotes RFLPs
T29 1334-1355 protein denotes HLA class II antigens
T30 1392-1399 protein denotes Ro(SSA)
T31 1484-1494 DNA denotes loci occur
T32 1510-1517 protein denotes Ro(SSA)

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
1967259-0#5#11#gene6737 5-11 gene6737 denotes Ro(SSA
1967259-0#78#106#diseaseC0024141 78-106 diseaseC0024141 denotes systemic lupus erythematosus
5#11#gene673778#106#diseaseC0024141 1967259-0#5#11#gene6737 1967259-0#78#106#diseaseC0024141 associated_with Ro(SSA,systemic lupus erythematosus

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-116 Sentence denotes Anti-Ro(SSA) autoantibodies are associated with T cell receptor beta genes in systemic lupus erythematosus patients.
S2 117-252 Sentence denotes Several of the heterogeneous clinical manifestations of systemic lupus erythematosus have been associated with specific autoantibodies.
S3 253-398 Sentence denotes Associations between HLA class II antigens and autoantibodies to the ribonucleoproteins Ro(SSA) and La(SSB) have been reported in these patients.
S4 399-564 Sentence denotes Because HLA class II molecules present antigen to T cell receptors (TCRs), we have searched for a TCR gene associated with the production of anti-Ro(SSA) antibodies.
S5 565-830 Sentence denotes A pair of restriction fragment length polymorphisms (RFLPs), one of which hybridizes to the TCR constant region C beta 1 and the other to the C beta 2 gene, has been identified, suggesting these may be genotypic markers for an extended region of the TCR beta locus.
S6 831-1032 Sentence denotes This RFLP pair occurs in 76% of patients with Ro(SSA) precipitins, 84% of anti-Ro(SSA)-positive patients lacking La(SSB) precipitins, but only 41% of the patients lacking both precipitins (P = 0.0004).
S7 1033-1283 Sentence denotes This disproportionate occurrence in a subset of lupus patients indicates that these RFLPs are not disease susceptibility markers, but rather are important markers for TCR genes whose products are involved in the production of anti-Ro(SSA) antibodies.
S8 1284-1518 Sentence denotes The majority of patients who have these RFLPs and HLA class II antigens previously associated with the anti-Ro(SSA) response make this antibody, suggesting that interactions between products of these loci occur in response to Ro(SSA).

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 78-115 NP denotes systemic lupus erythematosus patients
C2 341-348 NP denotes Ro(SSA)
C3 383-397 NP denotes these patients
C4 540-563 NP denotes anti-Ro(SSA) antibodies
C5 565-616 NP denotes A pair of restriction fragment length polymorphisms
C6 754-759 NP denotes these
C7 831-845 NP denotes This RFLP pair
C8 981-1018 NP denotes the patients lacking both precipitins
C10 1081-1095 NP denotes lupus patients
C9 1069-1095 NP denotes a subset of lupus patients
C11 1111-1122 NP denotes these RFLPs
C12 1259-1282 NP denotes anti-Ro(SSA) antibodies
C13 1318-1329 NP denotes these RFLPs
C14 1414-1427 NP denotes this antibody
C15 1510-1517 NP denotes Ro(SSA)
R1 C3 C1 coref-ident these patients,systemic lupus erythematosus patients
R2 C6 C5 coref-pron these,A pair of restriction fragment length polymorphisms
R3 C7 C5 coref-ident This RFLP pair,A pair of restriction fragment length polymorphisms
R4 C10 C3 coref-ident lupus patients,these patients
R5 C9 C8 coref-ident a subset of lupus patients,the patients lacking both precipitins
R6 C11 C7 coref-ident these RFLPs,This RFLP pair
R7 C12 C4 coref-ident anti-Ro(SSA) antibodies,anti-Ro(SSA) antibodies
R8 C13 C11 coref-ident these RFLPs,these RFLPs
R9 C14 C12 coref-ident this antibody,anti-Ro(SSA) antibodies
R10 C15 C2 coref-ident Ro(SSA),Ro(SSA)

GENIAcorpus

Id Subject Object Predicate Lexical cue
T11 353-360 protein_molecule denotes La(SSB)
T1 0-27 protein_family_or_group denotes Anti-Ro(SSA) autoantibodies
T2 48-74 DNA_family_or_group denotes T cell receptor beta genes
T3 78-106 other_name denotes systemic lupus erythematosus
T4 132-169 other_name denotes heterogeneous clinical manifestations
T5 173-201 other_name denotes systemic lupus erythematosus
T6 237-251 protein_family_or_group denotes autoantibodies
T7 274-295 protein_family_or_group denotes HLA class II antigens
T8 300-314 protein_family_or_group denotes autoantibodies
T9 322-340 protein_family_or_group denotes ribonucleoproteins
T10 341-348 protein_molecule denotes Ro(SSA)
T12 407-429 protein_family_or_group denotes HLA class II molecules
T13 449-465 protein_family_or_group denotes T cell receptors
T14 467-471 protein_family_or_group denotes TCRs
T15 497-505 DNA_family_or_group denotes TCR gene
T16 540-545 protein_family_or_group denotes anti-
T17 545-552 protein_molecule denotes Ro(SSA)
T18 575-616 DNA_family_or_group denotes restriction fragment length polymorphisms
T19 618-623 DNA_family_or_group denotes RFLPs
T20 657-685 DNA_domain_or_region denotes TCR constant region C beta 1
T21 707-720 DNA_domain_or_region denotes C beta 2 gene
T22 767-784 other_name denotes genotypic markers
T23 815-829 DNA_domain_or_region denotes TCR beta locus
T24 836-845 DNA_domain_or_region denotes RFLP pair
T25 863-871 multi_cell denotes patients
T26 877-884 protein_molecule denotes Ro(SSA)
T27 905-910 multi_cell denotes anti-
T28 910-917 protein_molecule denotes Ro(SSA)
T29 927-935 multi_cell denotes patients
T30 944-951 protein_molecule denotes La(SSB)
T31 952-963 protein_family_or_group denotes precipitins
T32 985-993 multi_cell denotes patients
T33 1007-1018 protein_family_or_group denotes precipitins
T34 1081-1086 multi_cell denotes lupus
T35 1087-1095 multi_cell denotes patients
T36 1117-1122 DNA_family_or_group denotes RFLPs
T37 1200-1209 DNA_domain_or_region denotes TCR genes
T38 1259-1264 protein_family_or_group denotes anti-
T39 1264-1271 protein_molecule denotes Ro(SSA)
T40 1300-1308 multi_cell denotes patients
T41 1324-1329 DNA_family_or_group denotes RFLPs
T42 1334-1355 protein_molecule denotes HLA class II antigens
T43 1387-1392 other_name denotes anti-
T44 1392-1399 protein_molecule denotes Ro(SSA)
T45 1484-1494 DNA_domain_or_region denotes loci occur
T46 1510-1517 protein_molecule denotes Ro(SSA)