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PubMed:1966869 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 100-124 protein denotes glucocorticoid receptors
T2 414-430 protein denotes pokeweed mitogen
T3 432-435 protein denotes PWM
T4 588-611 protein denotes glucocorticoid receptor
T5 672-675 protein denotes PHA
T6 704-707 protein denotes PWM
T7 1106-1109 protein denotes PWM
T8 1442-1465 protein denotes glucocorticoid receptor
T9 1492-1495 protein denotes PWM
T10 1640-1662 protein denotes interleukin-1 receptor

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-125 Sentence denotes In vivo and in vitro effects of glucocorticoids on lymphocyte proliferation in man: relationship to glucocorticoid receptors.
S2 126-269 Sentence denotes Interrelations between the hypothalamic-pituitary-adrenal system (HPA) and the immune system represent a well-documented biological phenomenon.
S3 270-506 Sentence denotes While in vitro administration of glucocorticoids may inhibit concanavalin A (Con A)- and phytohemagglutinin (PHA)-induced T-cell proliferation, pokeweed mitogen (PWM)-driven B-cell mitogenesis is relatively resistant to glucocorticoids.
S4 507-801 Sentence denotes To further explore the link between the HPA and the immune system in relation to glucocorticoid receptor function, dose-response curves were obtained for Con A- and PHA-induced T-cell mitogenesis, PWM-generated B-cell mitogenesis and spontaneous lymphocyte proliferation in 13 healthy controls.
S5 802-1069 Sentence denotes Glucocorticoid effects were assessed in vivo by depletion of endogenous glucocorticoids after oral administration of 1.5 g metyrapone (MET) and subsequent glucocorticoid replacement, and in vitro by incubation of the cells with different doses of dexamethasone (DEX).
S6 1070-1320 Sentence denotes There was a significant decrease in PWM-induced B-cell mitogenesis and a more pronounced effect of DEX administered in vitro on spontaneous lymphocyte proliferation after MET treatment when compared with the DEX plus MET pretreated condition in vivo.
S7 1321-1475 Sentence denotes These data suggest that the inhibition of spontaneous lymphocyte proliferation by glucocorticoids in vitro is related to glucocorticoid receptor function.
S8 1476-1673 Sentence denotes The decrease in PWM-generated B-cell proliferation following cortisol depletion by MET may be seen in connection with impaired glucocorticoid-mediated induction of interleukin-1 receptor synthesis.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 32-47 NP denotes glucocorticoids
C2 126-218 NP denotes Interrelations between the hypothalamic-pituitary-adrenal system (HPA) and the immune system
C3 303-318 NP denotes glucocorticoids
C4 414-462 NP denotes pokeweed mitogen (PWM)-driven B-cell mitogenesis
C5 490-505 NP denotes glucocorticoids
C6 526-572 NP denotes the link between the HPA and the immune system
C7 588-620 NP denotes glucocorticoid receptor function
C8 704-736 NP denotes PWM-generated B-cell mitogenesis
C9 741-777 NP denotes spontaneous lymphocyte proliferation
C10 919-941 NP denotes 1.5 g metyrapone (MET)
C11 1049-1068 NP denotes dexamethasone (DEX)
C12 1106-1136 NP denotes PWM-induced B-cell mitogenesis
C13 1169-1172 NP denotes DEX
C14 1198-1234 NP denotes spontaneous lymphocyte proliferation
C15 1363-1399 NP denotes spontaneous lymphocyte proliferation
C16 1403-1418 NP denotes glucocorticoids
C17 1442-1474 NP denotes glucocorticoid receptor function
C18 1559-1562 NP denotes MET
R1 C3 C1 coref-ident glucocorticoids,glucocorticoids
R2 C5 C3 coref-ident glucocorticoids,glucocorticoids
R3 C6 C2 coref-ident the link between the HPA and the immune system,Interrelations between the hypothalamic-pituitary-adrenal system (HPA) and the immune system
R4 C8 C4 coref-ident PWM-generated B-cell mitogenesis,pokeweed mitogen (PWM)-driven B-cell mitogenesis
R5 C12 C8 coref-ident PWM-induced B-cell mitogenesis,PWM-generated B-cell mitogenesis
R6 C13 C11 coref-ident DEX,dexamethasone (DEX)
R7 C14 C9 coref-ident spontaneous lymphocyte proliferation,spontaneous lymphocyte proliferation
R8 C15 C14 coref-ident spontaneous lymphocyte proliferation,spontaneous lymphocyte proliferation
R9 C16 C5 coref-ident glucocorticoids,glucocorticoids
R10 C17 C7 coref-ident glucocorticoid receptor function,glucocorticoid receptor function
R11 C18 C10 coref-ident MET,1.5 g metyrapone (MET)

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 32-47 lipid denotes glucocorticoids
T2 51-75 other_name denotes lymphocyte proliferation
T3 79-82 multi_cell denotes man
T4 100-124 protein_family_or_group denotes glucocorticoid receptors
T5 153-190 body_part denotes hypothalamic-pituitary-adrenal system
T6 192-195 body_part denotes HPA
T7 205-218 body_part denotes immune system
T8 247-268 other_name denotes biological phenomenon
T9 303-318 lipid denotes glucocorticoids
T10 414-430 protein_molecule denotes pokeweed mitogen
T11 432-435 protein_molecule denotes PWM
T12 490-505 lipid denotes glucocorticoids
T13 547-550 body_part denotes HPA
T14 559-572 body_part denotes immune system
T15 588-611 protein_family_or_group denotes glucocorticoid receptor
T16 661-666 other_organic_compound denotes Con A
T17 672-675 protein_molecule denotes PHA
T18 704-707 protein_molecule denotes PWM
T19 753-777 other_name denotes lymphocyte proliferation
T20 784-800 multi_cell denotes healthy controls
T21 863-873 lipid denotes endogenous
T22 874-889 lipid denotes glucocorticoids
T23 896-915 other_name denotes oral administration
T24 919-935 other_organic_compound denotes 1.5 g metyrapone
T25 937-940 other_organic_compound denotes MET
T26 957-971 lipid denotes glucocorticoid
T27 1049-1062 lipid denotes dexamethasone
T28 1064-1067 lipid denotes DEX
T29 1106-1109 protein_molecule denotes PWM
T30 1169-1172 lipid denotes DEX
T31 1210-1234 other_name denotes lymphocyte proliferation
T32 1241-1244 other_organic_compound denotes MET
T33 1278-1281 lipid denotes DEX
T34 1287-1290 other_organic_compound denotes MET
T35 1375-1399 other_name denotes lymphocyte proliferation
T36 1403-1418 lipid denotes glucocorticoids
T37 1442-1456 lipid denotes glucocorticoid
T38 1492-1495 protein_molecule denotes PWM
T39 1537-1545 lipid denotes cortisol
T40 1559-1562 other_organic_compound denotes MET
T41 1603-1617 lipid denotes glucocorticoid
T42 1640-1662 protein_family_or_group denotes interleukin-1 receptor