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PubMed:1964088 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 180-183 gene:6900 denotes Tax
T1 195-216 disease:C0023493 denotes human T-cell leukemia
R1 T0 T1 associated_with Tax,human T-cell leukemia

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 50-81 protein denotes transcription factor NF-kappa B
T2 121-139 protein denotes HTLV-I Tax protein
T3 180-191 protein denotes Tax protein
T4 278-309 protein denotes transcription factor NF-kappa B
T5 418-449 protein denotes transcription factor NF-kappa B
T6 468-492 cell_line denotes Namalwa B lymphoid cells
T7 523-526 protein denotes Tax
T8 541-551 protein denotes NF-kappa B
T9 627-630 protein denotes Tax
T10 634-654 cell_line denotes Jurkat T lymphocytes
T11 689-698 protein denotes cytokines
T12 711-721 protein denotes NF-kappa B
T13 742-754 cell_line denotes Jurkat cells
T14 781-784 protein denotes Tax
T15 819-858 protein denotes mitogen-inducible transcription factors
T16 868-871 protein denotes Fos
T17 876-879 protein denotes Jun
T18 978-981 protein denotes Tax
T19 1047-1050 protein denotes Tax

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-140 Sentence denotes Suppression of signals required for activation of transcription factor NF-kappa B in cells constitutively expressing the HTLV-I Tax protein.
S2 141-310 Sentence denotes Transient short-term expression of the Tax protein of human T-cell leukemia virus type-I (HTLV-I) leads to activation of the pleiotropic transcription factor NF-kappa B.
S3 311-527 Sentence denotes Consistent with findings obtained with transient expression assays, we observed marked accumulation of the transcription factor NF-kappa B in the nucleus of Namalwa B lymphoid cells, which constitutively express Tax.
S4 528-655 Sentence denotes In contrast, NF-kappa B activity was not detected in the nucleus following long-term expression of Tax in Jurkat T lymphocytes.
S5 656-785 Sentence denotes The ability of both mitogens and cytokines to activate NF-kappa B was also blocked in Jurkat cells constitutively expressing Tax.
S6 786-896 Sentence denotes However, the activation of other mitogen-inducible transcription factors, such as Fos and Jun, was unaffected.
S7 897-1016 Sentence denotes Thus, depending on the cellular environment, the short- and long-term effects of Tax expression can be quite different.
S8 1017-1181 Sentence denotes Consequently, one function of Tax in cells infected with HTLV-I might involve cell-type-specific suppression, as opposed to activation, of distinct signal pathways.
S9 1182-1328 Sentence denotes The cells lines described here should be useful for the delineation of signaling pathways utilized in the selective regulation of gene expression.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 50-81 NP denotes transcription factor NF-kappa B
C1 36-81 NP denotes activation of transcription factor NF-kappa B
C3 117-139 NP denotes the HTLV-I Tax protein
C4 176-238 NP denotes the Tax protein of human T-cell leukemia virus type-I (HTLV-I)
C6 262-309 NP denotes the pleiotropic transcription factor NF-kappa B
C5 248-309 NP denotes activation of the pleiotropic transcription factor NF-kappa B
C7 414-449 NP denotes the transcription factor NF-kappa B
C8 453-492 NP denotes the nucleus of Namalwa B lymphoid cells
C9 494-499 NP denotes which
C10 523-526 NP denotes Tax
C11 581-592 NP denotes the nucleus
C12 627-630 NP denotes Tax
C13 634-654 NP denotes Jurkat T lymphocytes
C14 711-721 NP denotes NF-kappa B
C15 742-754 NP denotes Jurkat cells
C16 781-784 NP denotes Tax
C17 1047-1050 NP denotes Tax
R1 C4 C3 coref-ident the Tax protein of human T-cell leukemia virus type-I (HTLV-I),the HTLV-I Tax protein
R2 C6 C2 coref-ident the pleiotropic transcription factor NF-kappa B,transcription factor NF-kappa B
R3 C5 C1 coref-ident activation of the pleiotropic transcription factor NF-kappa B,activation of transcription factor NF-kappa B
R4 C7 C6 coref-ident the transcription factor NF-kappa B,the pleiotropic transcription factor NF-kappa B
R5 C9 C8 coref-relat which,the nucleus of Namalwa B lymphoid cells
R6 C11 C8 coref-ident the nucleus,the nucleus of Namalwa B lymphoid cells
R7 C12 C10 coref-ident Tax,Tax
R8 C14 C7 coref-ident NF-kappa B,the transcription factor NF-kappa B
R9 C15 C13 coref-ident Jurkat cells,Jurkat T lymphocytes
R10 C16 C12 coref-ident Tax,Tax
R11 C17 C16 coref-ident Tax,Tax

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 50-70 protein_molecule denotes transcription factor
T2 71-81 protein_molecule denotes NF-kappa B
T3 121-139 protein_molecule denotes HTLV-I Tax protein
T4 180-191 protein_molecule denotes Tax protein
T5 195-229 virus denotes human T-cell leukemia virus type-I
T6 231-237 virus denotes HTLV-I
T7 278-298 protein_molecule denotes transcription factor
T8 299-309 protein_molecule denotes NF-kappa B
T9 350-377 other_name denotes transient expression assays
T10 418-438 protein_molecule denotes transcription factor
T11 439-449 protein_molecule denotes NF-kappa B
T12 468-492 cell_line denotes Namalwa B lymphoid cells
T13 523-526 protein_molecule denotes Tax
T14 541-551 protein_molecule denotes NF-kappa B
T15 627-630 protein_molecule denotes Tax
T16 634-654 cell_line denotes Jurkat T lymphocytes
T17 676-684 other_name denotes mitogens
T18 689-698 protein_molecule denotes cytokines
T19 711-721 protein_molecule denotes NF-kappa B
T20 742-754 cell_line denotes Jurkat cells
T21 781-784 protein_molecule denotes Tax
T22 819-858 protein_family_or_group denotes mitogen-inducible transcription factors
T23 868-871 protein_molecule denotes Fos
T24 876-879 protein_molecule denotes Jun
T25 920-940 other_name denotes cellular environment
T26 978-981 protein_molecule denotes Tax
T27 1047-1050 protein_molecule denotes Tax
T28 1074-1080 virus denotes HTLV-I
T29 1095-1125 other_name denotes cell-type-specific suppression
T30 1156-1180 other_name denotes distinct signal pathways
T31 1312-1327 other_name denotes gene expression