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GlyCosmos6-Glycan-Motif-Image

Id	Subject	Object	Predicate	Lexical cue	image
T1	37-46	Glycan_Motif	denotes	sulfatide	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T4	402-412	Glycan_Motif	denotes	Sulfatides	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T7	578-587	Glycan_Motif	denotes	sulfatide	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T10	643-652	Glycan_Motif	denotes	sulfatide	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T13	695-698	Glycan_Motif	denotes	GD1	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81983KG\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G24638PB
T15	703-707	Glycan_Motif	denotes	GM1b	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G03277YI
T16	1340-1350	Glycan_Motif	denotes	sulfatides	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY

Glycosmos6-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue
T1	703-707	http://www.glycoepitope.jp/epitopes/EP0048	denotes	GM1b

sentences

Id	Subject	Object	Predicate	Lexical cue
TextSentencer_T1	0-183	Sentence	denotes	Polar lipid remodeling and increased sulfatide expression are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan.
TextSentencer_T2	184-401	Sentence	denotes	We report changes in gene and polar lipid expression induced by adenovirus-delivered wild-type (wt) p53 gene and chemotherapy of U87 MG glioblastoma cells, a treatment known to trigger apoptosis and cell cycle arrest.
TextSentencer_T3	402-663	Sentence	denotes	Sulfatides (sulfonated glycolipids) were most highly modulated by wild-type p53 treatment; however, no changes were observed in expression levels of mRNA for genes involved in sulfatide metabolism, indicating post-transcriptional control of sulfatide synthesis.
TextSentencer_T4	664-752	Sentence	denotes	Modulation of the aglycones of GD1 and GM1b was observed in wild-type p53-treated cells.
TextSentencer_T5	753-958	Sentence	denotes	The treatment also leads to an increase in phospholipids such as phosphatidyl inositols, phosphatidyl serines, phosphatidyl glycerols, and phosphatidyl ethanolamines, especially hydroxylated phospholipids.
TextSentencer_T6	959-1154	Sentence	denotes	These dramatic changes in the composition of cellular glycolipids in response to p53 gene expression and cytotoxic chemotherapy treatment indicate the large role that they play in cell signaling.
TextSentencer_T7	1155-1407	Sentence	denotes	The use of the human glioma cell line U87 appears to be an excellent model system both in tissue culture and in intracranial murine xenograft models to further characterize the role of sulfatides in modulating glioma responsivity to therapeutic agents.
T1	0-183	Sentence	denotes	Polar lipid remodeling and increased sulfatide expression are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan.
T2	184-401	Sentence	denotes	We report changes in gene and polar lipid expression induced by adenovirus-delivered wild-type (wt) p53 gene and chemotherapy of U87 MG glioblastoma cells, a treatment known to trigger apoptosis and cell cycle arrest.
T3	402-663	Sentence	denotes	Sulfatides (sulfonated glycolipids) were most highly modulated by wild-type p53 treatment; however, no changes were observed in expression levels of mRNA for genes involved in sulfatide metabolism, indicating post-transcriptional control of sulfatide synthesis.
T4	664-752	Sentence	denotes	Modulation of the aglycones of GD1 and GM1b was observed in wild-type p53-treated cells.
T5	753-958	Sentence	denotes	The treatment also leads to an increase in phospholipids such as phosphatidyl inositols, phosphatidyl serines, phosphatidyl glycerols, and phosphatidyl ethanolamines, especially hydroxylated phospholipids.
T6	959-1154	Sentence	denotes	These dramatic changes in the composition of cellular glycolipids in response to p53 gene expression and cytotoxic chemotherapy treatment indicate the large role that they play in cell signaling.
T7	1155-1407	Sentence	denotes	The use of the human glioma cell line U87 appears to be an excellent model system both in tissue culture and in intracranial murine xenograft models to further characterize the role of sulfatides in modulating glioma responsivity to therapeutic agents.

GlyCosmos6-Glycan-Motif-Structure

Id	Subject	Object	Predicate	Lexical cue
T1	37-46	https://glytoucan.org/Structures/Glycans/G40843KY	denotes	sulfatide
T2	37-46	https://glytoucan.org/Structures/Glycans/G72548RZ	denotes	sulfatide
T3	37-46	https://glytoucan.org/Structures/Glycans/G95090DW	denotes	sulfatide
T4	402-412	https://glytoucan.org/Structures/Glycans/G40843KY	denotes	Sulfatides
T5	402-412	https://glytoucan.org/Structures/Glycans/G72548RZ	denotes	Sulfatides
T6	402-412	https://glytoucan.org/Structures/Glycans/G95090DW	denotes	Sulfatides
T7	578-587	https://glytoucan.org/Structures/Glycans/G40843KY	denotes	sulfatide
T8	578-587	https://glytoucan.org/Structures/Glycans/G72548RZ	denotes	sulfatide
T9	578-587	https://glytoucan.org/Structures/Glycans/G95090DW	denotes	sulfatide
T10	643-652	https://glytoucan.org/Structures/Glycans/G40843KY	denotes	sulfatide
T11	643-652	https://glytoucan.org/Structures/Glycans/G72548RZ	denotes	sulfatide
T12	643-652	https://glytoucan.org/Structures/Glycans/G95090DW	denotes	sulfatide
T13	695-698	https://glytoucan.org/Structures/Glycans/G24638PB	denotes	GD1
T14	695-698	https://glytoucan.org/Structures/Glycans/G81983KG	denotes	GD1
T15	703-707	https://glytoucan.org/Structures/Glycans/G03277YI	denotes	GM1b
T16	1340-1350	https://glytoucan.org/Structures/Glycans/G40843KY	denotes	sulfatides
T17	1340-1350	https://glytoucan.org/Structures/Glycans/G72548RZ	denotes	sulfatides
T18	1340-1350	https://glytoucan.org/Structures/Glycans/G95090DW	denotes	sulfatides

DisGeNET

Id	Subject	Object	Predicate	Lexical cue
T0	123-126	gene:7157	denotes	p53
T1	82-88	disease:C0017638	denotes	glioma
R1	T0	T1	associated_with	p53,glioma

Allie

Id	Subject	Object	Predicate	Lexical cue
SS1_19557511_1_0	269-278	expanded	denotes	wild-type
SS2_19557511_1_0	280-282	abbr	denotes	wt
AE1_19557511_1_0	SS1_19557511_1_0	SS2_19557511_1_0	abbreviatedTo	wild-type,wt

DisGeNET5_gene_disease

Id	Subject	Object	Predicate	Lexical cue
19557511-0#123#126#gene7157	123-126	gene7157	denotes	p53
19557511-0#82#88#diseaseC0017638	82-88	diseaseC0017638	denotes	glioma
123#126#gene715782#88#diseaseC0017638	19557511-0#123#126#gene7157	19557511-0#82#88#diseaseC0017638	associated_with	p53,glioma

GlyCosmos15-Glycan

Id	Subject	Object	Predicate	Lexical cue	image
T1	703-707	Glycan	denotes	GM1b	https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI

HP-phenotype

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	82-88	Phenotype	denotes	glioma	HP:0009733
T2	320-332	Phenotype	denotes	glioblastoma	HP:0012174
T3	1176-1182	Phenotype	denotes	glioma	HP:0009733
T4	1365-1371	Phenotype	denotes	glioma	HP:0009733

mondo_disease

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	82-88	Disease	denotes	glioma	http://purl.obolibrary.org/obo/MONDO_0021042
T2	320-332	Disease	denotes	glioblastoma	http://purl.obolibrary.org/obo/MONDO_0018177\|http://purl.obolibrary.org/obo/MONDO_0020690
T4	1176-1182	Disease	denotes	glioma	http://purl.obolibrary.org/obo/MONDO_0021042
T5	1365-1371	Disease	denotes	glioma	http://purl.obolibrary.org/obo/MONDO_0021042

Glycan-GlyCosmos

Id	Subject	Object	Predicate	Lexical cue	image
T1	703-707	Glycan	denotes	GM1b	https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI

GlyCosmos-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	703-707	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	GM1b	http://www.glycoepitope.jp/epitopes/EP0048

GlyCosmos15-HP

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	82-88	Phenotype	denotes	glioma	HP:0009733
T2	320-332	Phenotype	denotes	glioblastoma	HP:0012174
T3	1176-1182	Phenotype	denotes	glioma	HP:0009733
T4	1365-1371	Phenotype	denotes	glioma	HP:0009733

GlyCosmos15-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	383-393	Body_part	denotes	cell cycle	http://purl.obolibrary.org/obo/UBERON_2000098
T2	1245-1251	Body_part	denotes	tissue	http://purl.obolibrary.org/obo/UBERON_0000479

GlyCosmos15-MONDO

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	82-88	Disease	denotes	glioma	MONDO:0021042\|MONDO:0100342
T3	320-332	Disease	denotes	glioblastoma	MONDO:0018177\|MONDO:0020690
T5	1176-1182	Disease	denotes	glioma	MONDO:0021042\|MONDO:0100342
T7	1365-1371	Disease	denotes	glioma	MONDO:0021042\|MONDO:0100342

GlyCosmos15-Taxon

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1170-1175	Organism	denotes	human	9606

GlyCosmos15-Sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-183	Sentence	denotes	Polar lipid remodeling and increased sulfatide expression are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan.
T2	184-401	Sentence	denotes	We report changes in gene and polar lipid expression induced by adenovirus-delivered wild-type (wt) p53 gene and chemotherapy of U87 MG glioblastoma cells, a treatment known to trigger apoptosis and cell cycle arrest.
T3	402-663	Sentence	denotes	Sulfatides (sulfonated glycolipids) were most highly modulated by wild-type p53 treatment; however, no changes were observed in expression levels of mRNA for genes involved in sulfatide metabolism, indicating post-transcriptional control of sulfatide synthesis.
T4	664-752	Sentence	denotes	Modulation of the aglycones of GD1 and GM1b was observed in wild-type p53-treated cells.
T5	753-958	Sentence	denotes	The treatment also leads to an increase in phospholipids such as phosphatidyl inositols, phosphatidyl serines, phosphatidyl glycerols, and phosphatidyl ethanolamines, especially hydroxylated phospholipids.
T6	959-1154	Sentence	denotes	These dramatic changes in the composition of cellular glycolipids in response to p53 gene expression and cytotoxic chemotherapy treatment indicate the large role that they play in cell signaling.
T7	1155-1407	Sentence	denotes	The use of the human glioma cell line U87 appears to be an excellent model system both in tissue culture and in intracranial murine xenograft models to further characterize the role of sulfatides in modulating glioma responsivity to therapeutic agents.

GlyCosmos15-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	703-707	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	GM1b	http://www.glycoepitope.jp/epitopes/EP0048

GlyCosmos15-FMA

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1245-1251	Body_part	denotes	tissue	FMA:9637

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1170-1175	OrganismTaxon	denotes	human	9606

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	383-393	Body_part	denotes	cell cycle	http://purl.obolibrary.org/obo/UBERON_2000098
T2	1245-1251	Body_part	denotes	tissue	http://purl.obolibrary.org/obo/UBERON_0000479