| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-102 |
Sentence |
denotes |
A bireactant, irreversible, active-site-directed inhibitor of beta-D-galactosidase (Escherichia coli). |
| TextSentencer_T2 |
103-188 |
Sentence |
denotes |
Synthesis and properties of (1/2,5,6)-2-(3-azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol. |
| TextSentencer_T3 |
189-347 |
Sentence |
denotes |
(1/2,5,6)-2-(3-Azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol (1) was synthesized and was found to irreversibly inactivate beta-D-galactosidase (Escherichia coli). |
| TextSentencer_T4 |
348-447 |
Sentence |
denotes |
The inactivation was prevented by the presence of isopropyl 1-thio-beta-D-galactopyranoside (IPTG). |
| TextSentencer_T5 |
448-550 |
Sentence |
denotes |
The vinyloxirane group of 1 reacted with water and other nucleophiles, especially at higher pH values. |
| TextSentencer_T6 |
551-682 |
Sentence |
denotes |
Reaction of 1 with beta-D-galactosidase was slow enough so that a competitive-inhibition constant (Ki) of 29mM could be determined. |
| TextSentencer_T7 |
683-984 |
Sentence |
denotes |
The inhibition constant for (1,2/3,6)-6-(3-azibutylthio)-2-bromo-4-cyclohexene-1,3-diol (2), the precursor of the bireactant inhibitor 1, was 13 mM, while that of (1,3/2,4)-3-(3-azibutylthio)-5-cyclohexene-1,2,4-triol (3), the product formed when the reactant is allowed to react with water, was 23mM. |
| TextSentencer_T8 |
985-1261 |
Sentence |
denotes |
After irradiation by light, beta-D-galactosidase that had initially been treated with the bireactant compound and then digested with trypsin, showed a new pattern of elution from h.p.l.c., indicating that there was reaction at two regions of the beta-D-galactosidase molecule. |
| T1 |
0-102 |
Sentence |
denotes |
A bireactant, irreversible, active-site-directed inhibitor of beta-D-galactosidase (Escherichia coli). |
| T2 |
103-188 |
Sentence |
denotes |
Synthesis and properties of (1/2,5,6)-2-(3-azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol. |
| T3 |
189-347 |
Sentence |
denotes |
(1/2,5,6)-2-(3-Azibutylthio)-5,6-epoxy-3-cyclohexen-1-ol (1) was synthesized and was found to irreversibly inactivate beta-D-galactosidase (Escherichia coli). |
| T4 |
348-447 |
Sentence |
denotes |
The inactivation was prevented by the presence of isopropyl 1-thio-beta-D-galactopyranoside (IPTG). |
| T5 |
448-550 |
Sentence |
denotes |
The vinyloxirane group of 1 reacted with water and other nucleophiles, especially at higher pH values. |
| T6 |
551-682 |
Sentence |
denotes |
Reaction of 1 with beta-D-galactosidase was slow enough so that a competitive-inhibition constant (Ki) of 29mM could be determined. |
| T7 |
683-984 |
Sentence |
denotes |
The inhibition constant for (1,2/3,6)-6-(3-azibutylthio)-2-bromo-4-cyclohexene-1,3-diol (2), the precursor of the bireactant inhibitor 1, was 13 mM, while that of (1,3/2,4)-3-(3-azibutylthio)-5-cyclohexene-1,2,4-triol (3), the product formed when the reactant is allowed to react with water, was 23mM. |
| T8 |
985-1261 |
Sentence |
denotes |
After irradiation by light, beta-D-galactosidase that had initially been treated with the bireactant compound and then digested with trypsin, showed a new pattern of elution from h.p.l.c., indicating that there was reaction at two regions of the beta-D-galactosidase molecule. |
