PubMed:19536134 / 964-1202
Annnotations
LitCoin-sentences
{"project":"LitCoin-sentences","denotations":[{"id":"T8","span":{"begin":0,"end":238},"obj":"Sentence"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-entities
{"project":"LitCoin-entities","denotations":[{"id":"6224","span":{"begin":77,"end":81},"obj":"GeneOrGeneProduct"},{"id":"6225","span":{"begin":98,"end":101},"obj":"GeneOrGeneProduct"},{"id":"6226","span":{"begin":164,"end":173},"obj":"GeneOrGeneProduct"},{"id":"6227","span":{"begin":218,"end":228},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A34","pred":"db_id","subj":"6224","obj":"NCBIGene:26409"},{"id":"A35","pred":"db_id","subj":"6225","obj":"NCBIGene:12159"},{"id":"A36","pred":"db_id","subj":"6226","obj":"NCBIGene:17125"},{"id":"A37","pred":"db_id","subj":"6226","obj":"NCBIGene:17129"},{"id":"A38","pred":"db_id","subj":"6226","obj":"NCBIGene:55994"},{"id":"A39","pred":"db_id","subj":"6227","obj":"NCBIGene:26413"},{"id":"A40","pred":"db_id","subj":"6227","obj":"NCBIGene:26416"},{"id":"A41","pred":"db_id","subj":"6227","obj":"NCBIGene:26419"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-GeneOrGeneProduct-v0
{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T39","span":{"begin":6,"end":14},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":50,"end":54},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":77,"end":81},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":142,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":153,"end":159},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":164,"end":171},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":207,"end":217},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":218,"end":228},"obj":"GeneOrGeneProduct"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-GeneOrGeneProduct-v2
{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T27","span":{"begin":77,"end":81},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":153,"end":159},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":164,"end":171},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":218,"end":228},"obj":"GeneOrGeneProduct"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-Chemical-MeSH-CHEBI
{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T4","span":{"begin":218,"end":221},"obj":"ChemicalEntity"}],"attributes":[{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_6716"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-GeneOrGeneProduct-v3
{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T20","span":{"begin":77,"end":81},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":164,"end":171},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":218,"end":228},"obj":"GeneOrGeneProduct"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin_Mondo_095
{"project":"LitCoin_Mondo_095","denotations":[{"id":"T4","span":{"begin":218,"end":221},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0012041"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
LitCoin-training-merged
{"project":"LitCoin-training-merged","denotations":[{"id":"T4","span":{"begin":218,"end":221},"obj":"ChemicalEntity"},{"id":"T22","span":{"begin":218,"end":228},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":164,"end":171},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":77,"end":81},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_6716"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}
PMID_GLOBAL
{"project":"PMID_GLOBAL","denotations":[{"id":"T4","span":{"begin":218,"end":221},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0012041"}],"text":"These findings provide the first in vivo evidence in a mammalian system that TAK1 is required for BMP signalling and functions as an upstream activating kinase for Smad1/5/8 in addition to its known role in regulating MAP kinase pathways."}