PubMed:1944294
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 83-133 | protein | denotes | in vitro synthesized human glucocorticoid receptor |
| T2 | 215-244 | protein | denotes | human glucocorticoid receptor |
| T3 | 246-249 | protein | denotes | hGR |
| T4 | 307-330 | protein | denotes | In vitro translated hGR |
| T5 | 358-368 | protein | denotes | native hGR |
| T6 | 508-530 | protein | denotes | antipeptide antibodies |
| T7 | 549-552 | protein | denotes | hGR |
| T8 | 567-592 | protein | denotes | cell-free synthesized hGR |
| T9 | 628-690 | DNA | denotes | glucocorticoid response element (GRE)-containing DNA fragments |
| T10 | 815-839 | protein | denotes | glucocorticoid receptors |
| T11 | 841-864 | protein | denotes | In vitro translated hGR |
| T12 | 1291-1311 | protein | denotes | unliganded receptors |
| T13 | 1440-1463 | protein | denotes | in vitro synthesized GR |
| T14 | 1664-1680 | protein | denotes | receptor complex |
| T15 | 1757-1782 | protein | denotes | cell-free synthesized hGR |
| T16 | 1834-1846 | DNA | denotes | various DNAs |
| T17 | 1895-1898 | DNA | denotes | GRE |
| T18 | 1912-1958 | DNA | denotes | mouse mammary tumor virus-long terminal repeat |
| T19 | 1992-2005 | DNA | denotes | consensus GRE |
| T20 | 2068-2088 | DNA | denotes | regulatory sequences |
| T21 | 2094-2126 | DNA | denotes | glucocorticoid-repressible genes |
| T22 | 2222-2268 | DNA | denotes | mouse mammary tumor virus-long terminal repeat |
| T23 | 2388-2391 | protein | denotes | hGR |
| T24 | 2483-2486 | DNA | denotes | GRE |
| T25 | 2522-2545 | protein | denotes | glucocorticoid receptor |
| T26 | 2579-2594 | cell_type | denotes | mammalian cells |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 0-10 | cui:C0220825 | denotes | Evaluation |
| E2-ti-1 | 18-22 | cui:C0035820 | denotes | role |
| E3-ti-1 | 26-32 | cui:C1167622 | denotes | ligand |
| E4-ti-1 | 68-79 | cui:C1148673 | denotes | DNA binding |
| E5-ti-1 | 104-109 | cui:C0020114 | denotes | human |
| E6-ti-1 | 110-133 | cui:C0034809 | denotes | glucocorticoid receptor |
| T1 | 104-133 | PART_OF | denotes | human glucocorticoid receptor |
| E1-ab-1 | 150-161 | cui:C1148673 | denotes | DNA-binding |
| E2-ab-1 | 162-181 | cui:C0021069 | denotes | immunoprecipitation |
| E3-ab-1 | 203-211 | cui:C1516240 | denotes | capacity |
| E4-ab-1 | 215-220 | cui:C0020114 | denotes | human |
| E5-ab-1 | 221-244 | cui:C0034809 | denotes | glucocorticoid receptor |
| E6-ab-1 | 265-271 | cui:C0034493 | denotes | rabbit |
| E7-ab-1 | 272-284 | cui:C0035286 | denotes | reticulocyte |
| E8-ab-1 | 302-305 | cui:C0012854 | denotes | DNA |
| T2 | 215-244 | PART_OF | denotes | human glucocorticoid receptor |
| T3 | 297-301 | INTERACTS_WITH | denotes | bind |
| E1-ab-2 | 316-326 | cui:C0040710 | denotes | translated |
| E2-ab-2 | 327-330 | cui:C0020114 | denotes | hGR |
| E3-ab-2 | 327-330 | cui:C0034809 | denotes | hGR |
| E4-ab-2 | 358-364 | cui:C0302891 | denotes | native |
| E5-ab-2 | 365-368 | cui:C0020114 | denotes | hGR |
| E6-ab-2 | 365-368 | cui:C0034809 | denotes | hGR |
| E7-ab-2 | 400-422 | cui:C0037506 | denotes | sodium dodecyl sulfate |
| E8-ab-2 | 423-442 | cui:C0071500 | denotes | polyacrylamide gels |
| E9-ab-2 | 444-457 | cui:C0597428 | denotes | sedimentation |
| E10-ab-2 | 461-468 | cui:C0038636 | denotes | sucrose |
| E11-ab-2 | 469-476 | cui:C0178587 | denotes | density |
| E12-ab-2 | 477-486 | cui:C0439182 | denotes | gradients |
| E13-ab-2 | 492-502 | cui:C0205332 | denotes | reactivity |
| E14-ab-2 | 520-530 | cui:C0003241 | denotes | antibodies |
| E15-ab-2 | 549-552 | cui:C0020114 | denotes | hGR |
| E16-ab-2 | 549-552 | cui:C0034809 | denotes | hGR |
| T4 | 327-330 | PART_OF | denotes | hGR |
| T5 | 365-368 | PART_OF | denotes | hGR |
| T6 | 531-540 | PRODUCES | denotes | generated |
| T7 | 549-552 | PART_OF | denotes | hGR |
| E1-ab-3 | 557-565 | cui:C0442796 | denotes | addition |
| E2-ab-3 | 567-572 | cui:C0007634 | denotes | cell- |
| E3-ab-3 | 589-592 | cui:C0020114 | denotes | hGR |
| E4-ab-3 | 589-592 | cui:C0034809 | denotes | hGR |
| E5-ab-3 | 628-642 | cui:C0017710 | denotes | glucocorticoid |
| E6-ab-3 | 643-659 | cui:C0600508 | denotes | response element |
| E7-ab-3 | 666-676 | cui:C0332256 | denotes | containing |
| E8-ab-3 | 677-680 | cui:C0012854 | denotes | DNA |
| E9-ab-3 | 681-690 | cui:C0486805 | denotes | fragments |
| T8 | 589-592 | PART_OF | denotes | hGR |
| E1-ab-4 | 703-708 | cui:C1510438 | denotes | assay |
| E2-ab-4 | 709-715 | cui:C0449913 | denotes | system |
| E3-ab-4 | 756-770 | cui:C1517880 | denotes | ligand binding |
| E4-ab-4 | 794-805 | cui:C1148673 | denotes | DNA binding |
| E5-ab-4 | 815-839 | cui:C0034809 | denotes | glucocorticoid receptors |
| E1-ab-5 | 850-860 | cui:C0040710 | denotes | translated |
| E2-ab-5 | 861-864 | cui:C0020114 | denotes | hGR |
| E3-ab-5 | 861-864 | cui:C0034809 | denotes | hGR |
| E4-ab-5 | 890-901 | cui:C1148673 | denotes | DNA binding |
| E5-ab-5 | 925-939 | cui:C0017710 | denotes | glucocorticoid |
| T9 | 861-864 | PART_OF | denotes | hGR |
| E1-ab-6 | 941-950 | cui:C0087111 | denotes | Treatment |
| E2-ab-6 | 956-969 | cui:C0011777 | denotes | dexamethasone |
| E3-ab-6 | 996-1001 | cui:C0701303 | denotes | RU486 |
| E4-ab-6 | 1009-1019 | cui:C1524062 | denotes | additional |
| E5-ab-6 | 1020-1026 | cui:C1280500 | denotes | effect |
| E6-ab-6 | 1034-1038 | cui:C0012854 | denotes | DNA- |
| E7-ab-6 | 1038-1054 | cui:C0439155 | denotes | binding capacity |
| E8-ab-6 | 1060-1068 | cui:C0597357 | denotes | receptor |
| E9-ab-6 | 1069-1081 | cui:C1521827 | denotes | preparations |
| T10 | 951-955 | USES | denotes | with |
| T11 | 951-955 | USES | denotes | with |
| E1-ab-7 | 1135-1143 | cui:C0442796 | denotes | addition |
| E2-ab-7 | 1154-1160 | cui:C1167622 | denotes | ligand |
| E3-ab-7 | 1178-1189 | cui:C0205195 | denotes | combination |
| E4-ab-7 | 1213-1217 | cui:C1261552 | denotes | step |
| E5-ab-7 | 1227-1238 | cui:C1148673 | denotes | DNA binding |
| E6-ab-7 | 1242-1255 | cui:C0332232 | denotes | approximately |
| E7-ab-7 | 1258-1262 | cui:C0332462 | denotes | fold |
| E8-ab-7 | 1263-1267 | cui:C0205136 | denotes | over |
| E9-ab-7 | 1281-1290 | cui:C1515877 | denotes | activated |
| E10-ab-7 | 1302-1311 | cui:C0597357 | denotes | receptors |
| E1-ab-8 | 1313-1320 | cui:C0243192 | denotes | Agonist |
| E2-ab-8 | 1322-1335 | cui:C0011777 | denotes | dexamethasone |
| E3-ab-8 | 1341-1349 | cui:C0750482 | denotes | slightly |
| E4-ab-8 | 1355-1364 | cui:C1280500 | denotes | effective |
| E5-ab-8 | 1368-1378 | cui:C0183683 | denotes | supporting |
| E6-ab-8 | 1388-1399 | cui:C1148673 | denotes | DNA binding |
| E7-ab-8 | 1417-1422 | cui:C0701303 | denotes | RU486 |
| E1-ab-9 | 1425-1436 | cui:C1148673 | denotes | DNA binding |
| E2-ab-9 | 1483-1491 | cui:C0442796 | denotes | addition |
| E3-ab-9 | 1495-1511 | cui:C0074747 | denotes | sodium molybdate |
| E4-ab-9 | 1519-1527 | cui:C0597357 | denotes | receptor |
| E5-ab-9 | 1528-1540 | cui:C1521827 | denotes | preparations |
| E6-ab-9 | 1548-1555 | cui:C0038317 | denotes | steroid |
| E7-ab-9 | 1556-1564 | cui:C1524062 | denotes | addition |
| E1-ab-10 | 1589-1597 | cui:C0442796 | denotes | Addition |
| E2-ab-10 | 1622-1633 | cui:C1148673 | denotes | DNA binding |
| E3-ab-10 | 1660-1672 | cui:C0058595 | denotes | DNA-receptor |
| E4-ab-10 | 1673-1680 | cui:C0439855 | denotes | complex |
| E5-ab-10 | 1681-1690 | cui:C1522492 | denotes | formation |
| E6-ab-10 | 1694-1704 | cui:C0332453 | denotes | disruption |
| E7-ab-10 | 1712-1721 | cui:C0439855 | denotes | complexes |
| E1-ab-11 | 1727-1738 | cui:C0037791 | denotes | specificity |
| E2-ab-11 | 1742-1753 | cui:C1148673 | denotes | DNA binding |
| E3-ab-11 | 1757-1762 | cui:C0007634 | denotes | cell- |
| E4-ab-11 | 1779-1782 | cui:C0020114 | denotes | hGR |
| E5-ab-11 | 1779-1782 | cui:C0034809 | denotes | hGR |
| E6-ab-11 | 1796-1803 | cui:C1517331 | denotes | further |
| E7-ab-11 | 1807-1816 | cui:C0332128 | denotes | examining |
| E8-ab-11 | 1821-1830 | cui:C0085732 | denotes | abilities |
| E9-ab-11 | 1842-1846 | cui:C0012854 | denotes | DNAs |
| E10-ab-11 | 1895-1898 | cui:C0017710 | denotes | GRE |
| E11-ab-11 | 1895-1898 | cui:C0600508 | denotes | GRE |
| E12-ab-11 | 1912-1937 | cui:C0024662 | denotes | mouse mammary tumor virus |
| E13-ab-11 | 1938-1958 | cui:C0023978 | denotes | long terminal repeat |
| T12 | 1779-1782 | PART_OF | denotes | hGR |
| E1-ab-12 | 1960-1976 | cui:C0028953 | denotes | Oligonucleotides |
| E2-ab-12 | 1992-2001 | cui:C0376298 | denotes | consensus |
| E3-ab-12 | 2002-2005 | cui:C0017710 | denotes | GRE |
| E4-ab-12 | 2002-2005 | cui:C0600508 | denotes | GRE |
| E5-ab-12 | 2015-2019 | cui:C0205393 | denotes | most |
| E6-ab-12 | 2020-2029 | cui:C0442799 | denotes | efficient |
| E7-ab-12 | 2047-2056 | cui:C0486805 | denotes | fragments |
| E8-ab-12 | 2068-2088 | cui:C0314642 | denotes | regulatory sequences |
| E9-ab-12 | 2094-2108 | cui:C0017710 | denotes | glucocorticoid |
| E10-ab-12 | 2121-2126 | cui:C0017337 | denotes | genes |
| E11-ab-12 | 2141-2152 | cui:C0679932 | denotes | competitive |
| E12-ab-12 | 2162-2168 | cui:C0205171 | denotes | single |
| E13-ab-12 | 2178-2194 | cui:C0028953 | denotes | oligonucleotides |
| E14-ab-12 | 2200-2206 | cui:C1299582 | denotes | unable |
| E15-ab-12 | 2222-2247 | cui:C0024662 | denotes | mouse mammary tumor virus |
| E16-ab-12 | 2248-2268 | cui:C0023978 | denotes | long terminal repeat |
| E17-ab-12 | 2269-2280 | cui:C1148673 | denotes | DNA binding |
| E18-ab-12 | 2309-2316 | cui:C0150312 | denotes | present |
| E19-ab-12 | 2330-2334 | cui:C0205250 | denotes | high |
| E20-ab-12 | 2335-2349 | cui:C0086045 | denotes | concentrations |
| E1-ab-13 | 2366-2373 | cui:C0008972 | denotes | studies |
| E2-ab-13 | 2388-2391 | cui:C0020114 | denotes | hGR |
| E3-ab-13 | 2388-2391 | cui:C0034809 | denotes | hGR |
| E4-ab-13 | 2407-2413 | cui:C0034493 | denotes | rabbit |
| E5-ab-13 | 2414-2426 | cui:C0035286 | denotes | reticulocyte |
| E6-ab-13 | 2456-2460 | cui:C0445247 | denotes | same |
| E7-ab-13 | 2461-2471 | cui:C0871161 | denotes | properties |
| E8-ab-13 | 2483-2486 | cui:C0017710 | denotes | GRE |
| E9-ab-13 | 2483-2486 | cui:C0600508 | denotes | GRE |
| E10-ab-13 | 2496-2507 | cui:C1148673 | denotes | DNA binding |
| E11-ab-13 | 2522-2545 | cui:C0034809 | denotes | glucocorticoid receptor |
| E12-ab-13 | 2546-2553 | cui:C0150312 | denotes | present |
| E13-ab-13 | 2557-2566 | cui:C0010854 | denotes | cytosolic |
| E14-ab-13 | 2567-2575 | cui:C1555707 | denotes | extracts |
| E15-ab-13 | 2579-2594 | cui:C1512977 | denotes | mammalian cells |
| E16-ab-13 | 2599-2606 | cui:C0040300 | denotes | tissues |
| T13 | 2388-2391 | PART_OF | denotes | hGR |
| E1-ab-14 | 2608-2620 | cui:C0871364 | denotes | Similarities |
| E2-ab-14 | 2633-2640 | cui:C1280500 | denotes | effects |
| E3-ab-14 | 2644-2657 | cui:C0011777 | denotes | dexamethasone |
| E4-ab-14 | 2662-2667 | cui:C0701303 | denotes | RU486 |
| E5-ab-14 | 2704-2714 | cui:C0871161 | denotes | properties |
| E6-ab-14 | 2718-2723 | cui:C0701303 | denotes | RU486 |
| E7-ab-14 | 2727-2730 | cui:C1518422 | denotes | not |
| E8-ab-14 | 2762-2773 | cui:C1148673 | denotes | DNA binding |
| R1 | E6-ti-1 | T1 | subjectOf | glucocorticoid receptor,human glucocorticoid receptor |
| R2 | E5-ti-1 | T1 | objectOf | human,human glucocorticoid receptor |
| R3 | E5-ab-1 | T2 | subjectOf | glucocorticoid receptor,human glucocorticoid receptor |
| R4 | E4-ab-1 | T2 | objectOf | human,human glucocorticoid receptor |
| R5 | E5-ab-1 | T3 | subjectOf | glucocorticoid receptor,bind |
| R6 | E8-ab-1 | T3 | objectOf | DNA,bind |
| R7 | E3-ab-2 | T4 | subjectOf | hGR,hGR |
| R8 | E2-ab-2 | T4 | objectOf | hGR,hGR |
| R9 | E6-ab-2 | T5 | subjectOf | hGR,hGR |
| R10 | E5-ab-2 | T5 | objectOf | hGR,hGR |
| R11 | E14-ab-2 | T6 | subjectOf | antibodies,generated |
| R12 | E16-ab-2 | T6 | objectOf | hGR,generated |
| R13 | E16-ab-2 | T7 | subjectOf | hGR,hGR |
| R14 | E15-ab-2 | T7 | objectOf | hGR,hGR |
| R15 | E4-ab-3 | T8 | subjectOf | hGR,hGR |
| R16 | E3-ab-3 | T8 | objectOf | hGR,hGR |
| R17 | E3-ab-5 | T9 | subjectOf | hGR,hGR |
| R18 | E2-ab-5 | T9 | objectOf | hGR,hGR |
| R19 | E1-ab-6 | T10 | subjectOf | Treatment,with |
| R20 | E2-ab-6 | T10 | objectOf | dexamethasone,with |
| R21 | E1-ab-6 | T11 | subjectOf | Treatment,with |
| R22 | E3-ab-6 | T11 | objectOf | RU486,with |
| R23 | E5-ab-11 | T12 | subjectOf | hGR,hGR |
| R24 | E4-ab-11 | T12 | objectOf | hGR,hGR |
| R25 | E3-ab-13 | T13 | subjectOf | hGR,hGR |
| R26 | E2-ab-13 | T13 | objectOf | hGR,hGR |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-134 | Sentence | denotes | Evaluation of the role of ligand and thermal activation of specific DNA binding by in vitro synthesized human glucocorticoid receptor. |
| S2 | 135-306 | Sentence | denotes | We have used a DNA-binding/immunoprecipitation assay to analyze the capacity of human glucocorticoid receptor (hGR), generated in rabbit reticulocyte lysates, to bind DNA. |
| S3 | 307-553 | Sentence | denotes | In vitro translated hGR was indistinguishable from native hGR, as determined by migration on sodium dodecyl sulfate-polyacrylamide gels, sedimentation on sucrose density gradients, and reactivity with antipeptide antibodies generated against hGR. |
| S4 | 554-691 | Sentence | denotes | In addition, cell-free synthesized hGR was capable of specific binding to glucocorticoid response element (GRE)-containing DNA fragments. |
| S5 | 692-840 | Sentence | denotes | Using this assay system, we have evaluated the contributions of ligand binding and heat activation to DNA binding by these glucocorticoid receptors. |
| S6 | 841-940 | Sentence | denotes | In vitro translated hGR was capable of selective DNA binding even in the absence of glucocorticoid. |
| S7 | 941-1121 | Sentence | denotes | Treatment with dexamethasone or the antiglucocorticoid RU486 had no additional effect on the DNA-binding capacity when receptor preparations were maintained at 0 C (no activation). |
| S8 | 1122-1312 | Sentence | denotes | In contrast, addition of either ligand or antagonist in combination with a heat activation step promoted DNA binding by approximately 3-fold over that of heat-activated unliganded receptors. |
| S9 | 1313-1424 | Sentence | denotes | Agonist (dexamethasone) was slightly more effective in supporting specific DNA binding than antagonist (RU486). |
| S10 | 1425-1588 | Sentence | denotes | DNA binding by in vitro synthesized GR was blocked by the addition of sodium molybdate to the receptor preparations before steroid addition and thermal activation. |
| S11 | 1589-1722 | Sentence | denotes | Addition of KCl resulted in less DNA binding either due to blockage of DNA-receptor complex formation or disruption of the complexes. |
| S12 | 1723-1959 | Sentence | denotes | The specificity of DNA binding by cell-free synthesized hGR was analyzed further by examining the abilities of various DNAs to compete for binding to a naturally occurring GRE found in the mouse mammary tumor virus-long terminal repeat. |
| S13 | 1960-2350 | Sentence | denotes | Oligonucleotides containing the consensus GRE were the most efficient competitors, and fragments containing regulatory sequences from glucocorticoid-repressible genes were somewhat competitive, whereas single stranded oligonucleotides were unable to compete for mouse mammary tumor virus-long terminal repeat DNA binding, except when competitor was present at extremely high concentrations. |
| S14 | 2351-2607 | Sentence | denotes | Together these studies indicate that hGR synthesized in rabbit reticulocyte lysates displays many of the same properties, including GRE-specific DNA binding, observed for glucocorticoid receptor present in cytosolic extracts of mammalian cells and tissues. |
| S15 | 2608-2774 | Sentence | denotes | Similarities between the effects of dexamethasone and RU486 suggest that the antiglucocorticoid properties of RU486 do not occur at the level of specific DNA binding. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 26-32 | NP | denotes | ligand |
| C2 | 37-55 | NP | denotes | thermal activation |
| C4 | 68-71 | NP | denotes | DNA |
| C3 | 59-79 | NP | denotes | specific DNA binding |
| C6 | 110-124 | NP | denotes | glucocorticoid |
| C5 | 92-133 | NP | denotes | synthesized human glucocorticoid receptor |
| C8 | 221-235 | NP | denotes | glucocorticoid |
| C7 | 215-250 | NP | denotes | human glucocorticoid receptor (hGR) |
| C9 | 265-292 | NP | denotes | rabbit reticulocyte lysates |
| C10 | 302-305 | NP | denotes | DNA |
| C11 | 316-330 | NP | denotes | translated hGR |
| C12 | 358-368 | NP | denotes | native hGR |
| C13 | 549-552 | NP | denotes | hGR |
| C14 | 567-592 | NP | denotes | cell-free synthesized hGR |
| C15 | 628-665 | NP | denotes | glucocorticoid response element (GRE) |
| C16 | 775-790 | NP | denotes | heat activation |
| C18 | 794-797 | NP | denotes | DNA |
| C17 | 794-805 | NP | denotes | DNA binding |
| C20 | 815-829 | NP | denotes | glucocorticoid |
| C19 | 809-839 | NP | denotes | these glucocorticoid receptors |
| C21 | 850-864 | NP | denotes | translated hGR |
| C23 | 890-893 | NP | denotes | DNA |
| C22 | 880-901 | NP | denotes | selective DNA binding |
| C24 | 925-939 | NP | denotes | glucocorticoid |
| C25 | 956-969 | NP | denotes | dexamethasone |
| C26 | 973-1001 | NP | denotes | the antiglucocorticoid RU486 |
| C27 | 1060-1081 | NP | denotes | receptor preparations |
| C28 | 1154-1160 | NP | denotes | ligand |
| C29 | 1195-1212 | NP | denotes | a heat activation |
| C31 | 1227-1230 | NP | denotes | DNA |
| C30 | 1227-1238 | NP | denotes | DNA binding |
| C32 | 1268-1272 | NP | denotes | that |
| C33 | 1313-1336 | NP | denotes | Agonist (dexamethasone) |
| C35 | 1388-1391 | NP | denotes | DNA |
| C34 | 1379-1399 | NP | denotes | specific DNA binding |
| C36 | 1405-1423 | NP | denotes | antagonist (RU486) |
| C38 | 1425-1428 | NP | denotes | DNA |
| C37 | 1425-1436 | NP | denotes | DNA binding |
| C39 | 1515-1540 | NP | denotes | the receptor preparations |
| C40 | 1569-1587 | NP | denotes | thermal activation |
| C42 | 1622-1625 | NP | denotes | DNA |
| C41 | 1622-1633 | NP | denotes | DNA binding |
| C44 | 1742-1745 | NP | denotes | DNA |
| C43 | 1742-1753 | NP | denotes | DNA binding |
| C45 | 1757-1782 | NP | denotes | cell-free synthesized hGR |
| C46 | 1834-1846 | NP | denotes | various DNAs |
| C47 | 1895-1898 | NP | denotes | GRE |
| C48 | 1908-1958 | NP | denotes | the mouse mammary tumor virus-long terminal repeat |
| C49 | 1960-1976 | NP | denotes | Oligonucleotides |
| C50 | 1988-2005 | NP | denotes | the consensus GRE |
| C51 | 2162-2194 | NP | denotes | single stranded oligonucleotides |
| C52 | 2222-2268 | NP | denotes | mouse mammary tumor virus-long terminal repeat |
| C54 | 2269-2272 | NP | denotes | DNA |
| C53 | 2269-2280 | NP | denotes | DNA binding |
| C55 | 2388-2391 | NP | denotes | hGR |
| C56 | 2407-2434 | NP | denotes | rabbit reticulocyte lysates |
| C58 | 2496-2499 | NP | denotes | DNA |
| C57 | 2483-2507 | NP | denotes | GRE-specific DNA binding |
| C60 | 2522-2536 | NP | denotes | glucocorticoid |
| C59 | 2522-2545 | NP | denotes | glucocorticoid receptor |
| C61 | 2644-2657 | NP | denotes | dexamethasone |
| C62 | 2662-2667 | NP | denotes | RU486 |
| C63 | 2718-2723 | NP | denotes | RU486 |
| C65 | 2762-2765 | NP | denotes | DNA |
| C64 | 2753-2773 | NP | denotes | specific DNA binding |
| R1 | C8 | C6 | coref-ident | glucocorticoid,glucocorticoid |
| R2 | C7 | C5 | coref-ident | human glucocorticoid receptor (hGR),synthesized human glucocorticoid receptor |
| R3 | C10 | C4 | coref-ident | DNA,DNA |
| R4 | C11 | C7 | coref-other | translated hGR,human glucocorticoid receptor (hGR) |
| R5 | C12 | C11 | coref-other | native hGR,translated hGR |
| R6 | C13 | C7 | coref-ident | hGR,human glucocorticoid receptor (hGR) |
| R7 | C14 | C5 | coref-other | cell-free synthesized hGR,synthesized human glucocorticoid receptor |
| R8 | C16 | C2 | coref-ident | heat activation,thermal activation |
| R9 | C18 | C10 | coref-ident | DNA,DNA |
| R10 | C17 | C3 | coref-ident | DNA binding,specific DNA binding |
| R11 | C20 | C8 | coref-ident | glucocorticoid,glucocorticoid |
| R12 | C19 | C14 | coref-ident | these glucocorticoid receptors,cell-free synthesized hGR |
| R13 | C21 | C11 | coref-ident | translated hGR,translated hGR |
| R14 | C23 | C18 | coref-ident | DNA,DNA |
| R15 | C22 | C17 | coref-other | selective DNA binding,DNA binding |
| R16 | C24 | C20 | coref-ident | glucocorticoid,glucocorticoid |
| R17 | C28 | C1 | coref-ident | ligand,ligand |
| R18 | C29 | C16 | coref-ident | a heat activation,heat activation |
| R19 | C31 | C23 | coref-ident | DNA,DNA |
| R20 | C30 | C22 | coref-ident | DNA binding,selective DNA binding |
| R21 | C32 | C30 | coref-pron | that,DNA binding |
| R22 | C33 | C25 | coref-ident | Agonist (dexamethasone),dexamethasone |
| R23 | C35 | C31 | coref-ident | DNA,DNA |
| R24 | C34 | C30 | coref-other | specific DNA binding,DNA binding |
| R25 | C36 | C26 | coref-ident | antagonist (RU486),the antiglucocorticoid RU486 |
| R26 | C38 | C35 | coref-ident | DNA,DNA |
| R27 | C37 | C30 | coref-ident | DNA binding,DNA binding |
| R28 | C39 | C27 | coref-ident | the receptor preparations,receptor preparations |
| R29 | C40 | C29 | coref-ident | thermal activation,a heat activation |
| R30 | C42 | C38 | coref-ident | DNA,DNA |
| R31 | C41 | C37 | coref-ident | DNA binding,DNA binding |
| R32 | C44 | C42 | coref-ident | DNA,DNA |
| R33 | C43 | C41 | coref-ident | DNA binding,DNA binding |
| R34 | C45 | C14 | coref-ident | cell-free synthesized hGR,cell-free synthesized hGR |
| R35 | C46 | C44 | coref-ident | various DNAs,DNA |
| R36 | C47 | C15 | coref-ident | GRE,glucocorticoid response element (GRE) |
| R37 | C50 | C47 | coref-ident | the consensus GRE,GRE |
| R38 | C51 | C49 | coref-other | single stranded oligonucleotides,Oligonucleotides |
| R39 | C52 | C48 | coref-ident | mouse mammary tumor virus-long terminal repeat,the mouse mammary tumor virus-long terminal repeat |
| R40 | C54 | C46 | coref-ident | DNA,various DNAs |
| R41 | C53 | C43 | coref-ident | DNA binding,DNA binding |
| R42 | C55 | C13 | coref-ident | hGR,hGR |
| R43 | C56 | C9 | coref-ident | rabbit reticulocyte lysates,rabbit reticulocyte lysates |
| R44 | C58 | C54 | coref-ident | DNA,DNA |
| R45 | C57 | C53 | coref-other | GRE-specific DNA binding,DNA binding |
| R46 | C60 | C24 | coref-ident | glucocorticoid,glucocorticoid |
| R47 | C59 | C55 | coref-ident | glucocorticoid receptor,hGR |
| R48 | C61 | C33 | coref-ident | dexamethasone,Agonist (dexamethasone) |
| R49 | C62 | C36 | coref-ident | RU486,antagonist (RU486) |
| R50 | C63 | C62 | coref-ident | RU486,RU486 |
| R51 | C65 | C58 | coref-ident | DNA,DNA |
| R52 | C64 | C57 | coref-ident | specific DNA binding,GRE-specific DNA binding |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-32 | other_name | denotes | ligand |
| T2 | 37-55 | other_name | denotes | thermal activation |
| T3 | 59-79 | other_name | denotes | specific DNA binding |
| T4 | 83-133 | protein_molecule | denotes | in vitro synthesized human glucocorticoid receptor |
| T5 | 150-187 | other_name | denotes | DNA-binding/immunoprecipitation assay |
| T6 | 215-244 | protein_molecule | denotes | human glucocorticoid receptor |
| T7 | 246-249 | protein_molecule | denotes | hGR |
| T8 | 265-292 | other_name | denotes | rabbit reticulocyte lysates |
| T9 | 307-330 | protein_molecule | denotes | In vitro translated hGR |
| T10 | 358-368 | protein_family_or_group | denotes | native hGR |
| T11 | 400-442 | other_name | denotes | sodium dodecyl sulfate-polyacrylamide gels |
| T12 | 444-457 | other_name | denotes | sedimentation |
| T13 | 461-486 | other_name | denotes | sucrose density gradients |
| T14 | 508-530 | protein_family_or_group | denotes | antipeptide antibodies |
| T15 | 549-552 | protein_molecule | denotes | hGR |
| T16 | 567-592 | protein_molecule | denotes | cell-free synthesized hGR |
| T17 | 628-659 | DNA_domain_or_region | denotes | glucocorticoid response element |
| T18 | 661-664 | DNA_domain_or_region | denotes | GRE |
| T19 | 703-715 | other_name | denotes | assay system |
| T20 | 794-805 | other_name | denotes | DNA binding |
| T21 | 815-839 | protein_family_or_group | denotes | glucocorticoid receptors |
| T22 | 841-864 | protein_molecule | denotes | In vitro translated hGR |
| T23 | 925-939 | lipid | denotes | glucocorticoid |
| T24 | 956-969 | lipid | denotes | dexamethasone |
| T25 | 977-1001 | other_organic_compound | denotes | antiglucocorticoid RU486 |
| T26 | 1034-1054 | other_name | denotes | DNA-binding capacity |
| T27 | 1060-1081 | other_name | denotes | receptor preparations |
| T28 | 1227-1238 | other_name | denotes | DNA binding |
| T29 | 1291-1311 | protein_family_or_group | denotes | unliganded receptors |
| T30 | 1322-1335 | lipid | denotes | dexamethasone |
| T31 | 1379-1399 | other_name | denotes | specific DNA binding |
| T32 | 1417-1422 | other_organic_compound | denotes | RU486 |
| T33 | 1440-1463 | protein_family_or_group | denotes | in vitro synthesized GR |
| T34 | 1519-1540 | other_name | denotes | receptor preparations |
| T35 | 1548-1564 | other_name | denotes | steroid addition |
| T36 | 1569-1587 | other_name | denotes | thermal activation |
| T37 | 1601-1604 | inorganic | denotes | KCl |
| T38 | 1622-1633 | other_name | denotes | DNA binding |
| T39 | 1660-1664 | other_name | denotes | DNA- |
| T40 | 1664-1680 | protein_complex | denotes | receptor complex |
| T41 | 1742-1753 | other_name | denotes | DNA binding |
| T42 | 1757-1782 | protein_family_or_group | denotes | cell-free synthesized hGR |
| T43 | 1834-1846 | DNA_family_or_group | denotes | various DNAs |
| T44 | 1895-1898 | DNA_domain_or_region | denotes | GRE |
| T45 | 1912-1958 | DNA_domain_or_region | denotes | mouse mammary tumor virus-long terminal repeat |
| T46 | 1992-2001 | DNA_domain_or_region | denotes | consensus |
| T47 | 2002-2005 | DNA_domain_or_region | denotes | GRE |
| T48 | 2068-2088 | DNA_domain_or_region | denotes | regulatory sequences |
| T49 | 2094-2108 | lipid | denotes | glucocorticoid |
| T50 | 2178-2194 | polynucleotide | denotes | oligonucleotides |
| T51 | 2222-2268 | DNA_domain_or_region | denotes | mouse mammary tumor virus-long terminal repeat |
| T52 | 2269-2280 | other_name | denotes | DNA binding |
| T53 | 2388-2391 | protein_family_or_group | denotes | hGR |
| T54 | 2483-2486 | DNA_domain_or_region | denotes | GRE |
| T55 | 2486-2495 | other_name | denotes | -specific |
| T56 | 2496-2507 | other_name | denotes | DNA binding |
| T57 | 2522-2545 | protein_family_or_group | denotes | glucocorticoid receptor |
| T58 | 2557-2575 | cell_component | denotes | cytosolic extracts |
| T59 | 2579-2594 | cell_type | denotes | mammalian cells |
| T60 | 2599-2606 | tissue | denotes | tissues |
| T61 | 2644-2657 | lipid | denotes | dexamethasone |
| T62 | 2662-2667 | other_organic_compound | denotes | RU486 |
| T63 | 2685-2714 | other_name | denotes | antiglucocorticoid properties |
| T64 | 2718-2723 | other_organic_compound | denotes | RU486 |
| T65 | 2753-2761 | other_name | denotes | specific |
| T66 | 2762-2773 | other_name | denotes | DNA binding |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 2389-2392 | C0086418 | denotes | GR |
| T2 | 1780-1783 | C0086418 | denotes | GR |
| T3 | 862-865 | C0086418 | denotes | GR |
| T4 | 590-593 | C0086418 | denotes | GR |
| T5 | 216-221 | C0086418 | denotes | uman |
| T6 | 105-110 | C0086418 | denotes | uman |
| T7 | 2389-2392 | C0034809 | denotes | GR |
| T8 | 1780-1783 | C0034809 | denotes | GR |
| T9 | 862-865 | C0034809 | denotes | GR |
| T10 | 590-593 | C0034809 | denotes | GR |
| T11 | 222-245 | C0034809 | denotes | lucocorticoid receptor |
| T12 | 111-134 | C0034809 | denotes | lucocorticoid receptor. |
| T13 | 1155-1161 | C0023688 | denotes | igand |
| T14 | 27-33 | C0023688 | denotes | igand |
| T15 | 1441-1449 | C0021135 | denotes | n vitro |
| T16 | 842-850 | C0021135 | denotes | n vitro |
| T17 | 308-316 | C0021135 | denotes | n vitro |
| T18 | 84-92 | C0021135 | denotes | n vitro |
| T19 | 2484-2487 | C0017710 | denotes | RE- |
| T20 | 2003-2006 | C0017710 | denotes | RE |
| T21 | 2095-2109 | C0017710 | denotes | lucocorticoid- |
| T22 | 1896-1899 | C0017710 | denotes | RE |
| T23 | 926-940 | C0017710 | denotes | lucocorticoid. |
| T24 | 629-643 | C0017710 | denotes | lucocorticoid |
| T25 | 2484-2487 | C0600508 | denotes | RE- |
| T26 | 2003-2006 | C0600508 | denotes | RE |
| T27 | 1896-1899 | C0600508 | denotes | RE |
| T28 | 644-660 | C0600508 | denotes | esponse element |
| T29 | 1-11 | C1261322 | denotes | valuation |
| T30 | 2393-2404 | C1883254 | denotes | ynthesized |
| T31 | 1768-1779 | C1883254 | denotes | ynthesized |
| T32 | 1450-1461 | C1883254 | denotes | ynthesized |
| T33 | 578-589 | C1883254 | denotes | ynthesized |
| T34 | 93-104 | C1883254 | denotes | ynthesized |
| T35 | 2754-2762 | C0205369 | denotes | pecific |
| T36 | 2488-2496 | C0205369 | denotes | pecific |
| T37 | 1380-1388 | C0205369 | denotes | pecific |
| T38 | 609-617 | C0205369 | denotes | pecific |
| T39 | 60-68 | C0205369 | denotes | pecific |
| T40 | 19-23 | C1705810 | denotes | ole |
| T41 | 1418-1423 | C0701303 | denotes | U486) |
| T42 | 997-1002 | C0701303 | denotes | U486 |
| T43 | 2645-2658 | C0011777 | denotes | examethasone |
| T44 | 1323-1336 | C0011777 | denotes | examethasone) |
| T45 | 957-970 | C0011777 | denotes | examethasone |
| T46 | 2497-2508 | C1148673 | denotes | NA binding, |
| T47 | 2270-2281 | C1148673 | denotes | NA binding, |
| T48 | 1743-1754 | C1148673 | denotes | NA binding |
| T49 | 1623-1634 | C1148673 | denotes | NA binding |
| T50 | 1426-1437 | C1148673 | denotes | NA binding |
| T51 | 1389-1400 | C1148673 | denotes | NA binding |
| T52 | 1228-1239 | C1148673 | denotes | NA binding |
| T53 | 1035-1046 | C1148673 | denotes | NA-binding |
| T54 | 891-902 | C1148673 | denotes | NA binding |
| T55 | 795-806 | C1148673 | denotes | NA binding |
| T56 | 2408-2414 | C0034493 | denotes | abbit |
| T57 | 266-272 | C0034493 | denotes | abbit |
| T58 | 2223-2248 | C0024662 | denotes | ouse mammary tumor virus- |
| T59 | 1913-1938 | C0024662 | denotes | ouse mammary tumor virus- |
| T60 | 2249-2269 | C0023978 | denotes | ong terminal repeat |
| T61 | 1939-1959 | C0023978 | denotes | ong terminal repeat. |
| T62 | 2415-2427 | C0035286 | denotes | eticulocyte |
| T63 | 273-285 | C0035286 | denotes | eticulocyte |
| T64 | 851-861 | C0040710 | denotes | ranslated |
| T65 | 317-327 | C0040710 | denotes | ranslated |
| T66 | 1843-1847 | C0012854 | denotes | NAs |
| T67 | 1035-1038 | C0012854 | denotes | NA- |
| T68 | 303-306 | C0012854 | denotes | NA. |
| T69 | 1961-1977 | C0028953 | denotes | ligonucleotides |
| T70 | 2179-2195 | C0028953 | denotes | ligonucleotides |
| T71 | 401-423 | C0037506 | denotes | odium dodecyl sulfate- |
| T72 | 149-154 | C0000702 | denotes | DNA- |
| T73 | 521-531 | C0003241 | denotes | ntibodies |
| T74 | 1590-1598 | C1883712 | denotes | ddition |
| T75 | 1136-1144 | C1883712 | denotes | ddition |
| T76 | 558-566 | C1883712 | denotes | ddition, |
| T77 | 1578-1588 | C1879547 | denotes | ctivation. |
| T78 | 1282-1290 | C1879547 | denotes | ctivated |
| T79 | 1203-1212 | C1879547 | denotes | ctivation |
| T80 | 1110-1120 | C1879547 | denotes | ctivation) |
| T81 | 781-791 | C1879547 | denotes | ctivation |
| T82 | 2080-2089 | C0162326 | denotes | equences |
| T83 | 2558-2567 | C1383501 | denotes | ytosolic |
| T84 | 1993-2002 | C0376298 | denotes | onsensus |
| T85 | 462-469 | C0038636 | denotes | ucrose |
| T86 | 1863-1870 | C1167622 | denotes | inding |
| T87 | 618-625 | C1167622 | denotes | inding |
| T88 | 155-162 | C1167622 | denotes | inding/ |
| T89 | 298-302 | C1167622 | denotes | ind |
| T90 | 726-735 | C0220825 | denotes | valuated |
| T91 | 163-182 | C0021069 | denotes | mmunoprecipitation |
| T92 | 424-443 | C0071500 | denotes | olyacrylamide gels, |
| T93 | 1496-1512 | C0074747 | denotes | odium molybdate |
| T94 | 1822-1831 | C0085732 | denotes | bilities |
| T95 | 667-676 | C2700400 | denotes | ontaining |
| T96 | 2547-2554 | C0150312 | denotes | resent |
| T97 | 2310-2317 | C0150312 | denotes | resent |
| T98 | 1900-1905 | C0150312 | denotes | ound |
| T99 | 1520-1527 | C0597357 | denotes | eceptor |
| T100 | 1303-1312 | C0597357 | denotes | eceptors. |
| T101 | 1061-1069 | C0597357 | denotes | eceptor |
| T102 | 776-780 | C0018837 | denotes | eat |
| T103 | 1406-1416 | C0231491 | denotes | ntagonist |
| T104 | 1165-1175 | C0231491 | denotes | ntagonist |
| T105 | 2732-2737 | C2745955 | denotes | ccur |
| T106 | 1886-1895 | C2745955 | denotes | ccurring |
| T107 | 704-709 | C1510438 | denotes | ssay |
| T108 | 183-188 | C1510438 | denotes | ssay |
| T109 | 1529-1541 | C1521827 | denotes | reparations |
| T110 | 1070-1082 | C1521827 | denotes | reparations |
| T111 | 532-541 | C3146294 | denotes | enerated |
| T112 | 253-262 | C3146294 | denotes | enerated |
| T113 | 2705-2715 | C0871161 | denotes | roperties |
| T114 | 2462-2472 | C0871161 | denotes | roperties, |
| T115 | 2428-2435 | C1881488 | denotes | ysates |
| T116 | 286-293 | C1881488 | denotes | ysates, |
| T117 | 870-877 | C2698977 | denotes | apable |
| T118 | 598-605 | C2698977 | denotes | apable |
| T119 | 1047-1054 | C1516240 | denotes | apacity |
| T120 | 204-212 | C1516240 | denotes | apacity |
| T121 | 1758-1767 | C1183428 | denotes | ell-free |
| T122 | 568-577 | C1183428 | denotes | ell-free |
| T123 | 1763-1767 | C1996904 | denotes | ree |
| T124 | 573-577 | C1996904 | denotes | ree |
| T125 | 1549-1556 | C0038317 | denotes | teroid |
| T126 | 915-922 | C0332197 | denotes | bsence |
| T127 | 1314-1321 | C2987634 | denotes | gonist |
| T128 | 1788-1796 | C0936012 | denotes | nalyzed |
| T129 | 1649-1657 | C1706968 | denotes | lockage |
| T130 | 2600-2607 | C0040300 | denotes | issues. |
| T131 | 1126-1134 | C1979874 | denotes | ontrast, |
| T132 | 2436-2444 | C0870432 | denotes | isplays |
| T133 | 2048-2057 | C0332255 | denotes | ragments |
| T134 | 2474-2483 | C0332257 | denotes | ncluding |
| T135 | 2728-2731 | C1518422 | denotes | ot |
| T136 | 2367-2373 | C0947630 | denotes | tudies |
| T137 | 2352-2360 | C1883357 | denotes | ogether |
| T138 | 693-698 | C1524063 | denotes | sing |
| T139 | 144-148 | C1273517 | denotes | sed |
| T140 | 2669-2676 | C1705535 | denotes | uggest |
| T141 | 2580-2595 | C1512977 | denotes | ammalian cells |
| T142 | 710-716 | C0449913 | denotes | ystem, |
| T143 | 2201-2207 | C1299582 | denotes | nable |
| T144 | 2142-2153 | C0679932 | denotes | ompetitive, |
| T145 | 678-691 | C0684192 | denotes | NA fragments. |
| T146 | 2568-2576 | C2828366 | denotes | xtracts |
| T147 | 1259-1263 | C0332462 | denotes | old |
| T148 | 1808-1817 | C0332128 | denotes | xamining |
| T149 | 1797-1804 | C1517331 | denotes | urther |
| T150 | 942-951 | C0087111 | denotes | reatment |
| T151 | 388-397 | C1533574 | denotes | igration |
| T152 | 1695-1705 | C0332453 | denotes | isruption |
| T153 | 1088-1098 | C1314677 | denotes | aintained |
| T154 | 1728-1739 | C1511884 | denotes | pecificity |
| T155 | 2445-2449 | C0439064 | denotes | any |
| T156 | 2510-2518 | C1441672 | denotes | bserved |
| T157 | 2457-2461 | C0445247 | denotes | ame |
| T158 | 445-458 | C1384604 | denotes | edimentation |
| T159 | 1469-1476 | C0332206 | denotes | locked |
| T160 | 2745-2750 | C0456079 | denotes | evel |
| T161 | 1356-1365 | C1704419 | denotes | ffective |
| T162 | 740-753 | C1880177 | denotes | ontributions |
| T163 | 1606-1614 | C1274040 | denotes | esulted |
| T164 | 2609-2621 | C2348205 | denotes | imilarities |
| T165 | 493-503 | C0205332 | denotes | eactivity |
| T166 | 2163-2178 | C1979975 | denotes | ingle stranded |
| T167 | 2133-2140 | C2984079 | denotes | omewhat |
| T168 | 1665-1680 | C1523873 | denotes | eceptor complex |
| T169 | 1243-1256 | C0332232 | denotes | pproximately |
| T170 | 2021-2030 | C0442799 | denotes | fficient |
| T171 | 2016-2020 | C0205393 | denotes | ost |
| T172 | 757-771 | C1517880 | denotes | igand binding |
| T173 | 1214-1218 | C1704379 | denotes | tep |
| T174 | 1179-1190 | C1947911 | denotes | ombination |
| T175 | 1039-1054 | C0439155 | denotes | inding capacity |
| T176 | 1713-1722 | C1704241 | denotes | omplexes. |
| T177 | 1219-1227 | C0033414 | denotes | romoted |
| T178 | 2331-2335 | C1299351 | denotes | igh |
| T179 | 478-487 | C0812409 | denotes | radients, |
| T180 | 2336-2350 | C0086045 | denotes | oncentrations. |
| T181 | 470-477 | C0178587 | denotes | ensity |
| T182 | 2634-2641 | C1280500 | denotes | ffects |
| T183 | 359-365 | C0302891 | denotes | ative |
| T184 | 1835-1842 | C0440102 | denotes | arious |
| T185 | 1462-1464 | C1552950 | denotes | R |
| T186 | 1010-1020 | C1524062 | denotes | dditional |
| T187 | 1342-1350 | C0750482 | denotes | lightly |
| T188 | 1369-1379 | C0183683 | denotes | upporting |