
PubMed:1944294
Annnotations
jnlpba-st-training
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 83-133 | protein | denotes | in vitro synthesized human glucocorticoid receptor |
T2 | 215-244 | protein | denotes | human glucocorticoid receptor |
T3 | 246-249 | protein | denotes | hGR |
T4 | 307-330 | protein | denotes | In vitro translated hGR |
T5 | 358-368 | protein | denotes | native hGR |
T6 | 508-530 | protein | denotes | antipeptide antibodies |
T7 | 549-552 | protein | denotes | hGR |
T8 | 567-592 | protein | denotes | cell-free synthesized hGR |
T9 | 628-690 | DNA | denotes | glucocorticoid response element (GRE)-containing DNA fragments |
T10 | 815-839 | protein | denotes | glucocorticoid receptors |
T11 | 841-864 | protein | denotes | In vitro translated hGR |
T12 | 1291-1311 | protein | denotes | unliganded receptors |
T13 | 1440-1463 | protein | denotes | in vitro synthesized GR |
T14 | 1664-1680 | protein | denotes | receptor complex |
T15 | 1757-1782 | protein | denotes | cell-free synthesized hGR |
T16 | 1834-1846 | DNA | denotes | various DNAs |
T17 | 1895-1898 | DNA | denotes | GRE |
T18 | 1912-1958 | DNA | denotes | mouse mammary tumor virus-long terminal repeat |
T19 | 1992-2005 | DNA | denotes | consensus GRE |
T20 | 2068-2088 | DNA | denotes | regulatory sequences |
T21 | 2094-2126 | DNA | denotes | glucocorticoid-repressible genes |
T22 | 2222-2268 | DNA | denotes | mouse mammary tumor virus-long terminal repeat |
T23 | 2388-2391 | protein | denotes | hGR |
T24 | 2483-2486 | DNA | denotes | GRE |
T25 | 2522-2545 | protein | denotes | glucocorticoid receptor |
T26 | 2579-2594 | cell_type | denotes | mammalian cells |
semrep-sample
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
E1-ti-1 | 0-10 | cui:C0220825 | denotes | Evaluation |
E2-ti-1 | 18-22 | cui:C0035820 | denotes | role |
E3-ti-1 | 26-32 | cui:C1167622 | denotes | ligand |
E4-ti-1 | 68-79 | cui:C1148673 | denotes | DNA binding |
E5-ti-1 | 104-109 | cui:C0020114 | denotes | human |
E6-ti-1 | 110-133 | cui:C0034809 | denotes | glucocorticoid receptor |
T1 | 104-133 | PART_OF | denotes | human glucocorticoid receptor |
E1-ab-1 | 150-161 | cui:C1148673 | denotes | DNA-binding |
E2-ab-1 | 162-181 | cui:C0021069 | denotes | immunoprecipitation |
E3-ab-1 | 203-211 | cui:C1516240 | denotes | capacity |
E4-ab-1 | 215-220 | cui:C0020114 | denotes | human |
E5-ab-1 | 221-244 | cui:C0034809 | denotes | glucocorticoid receptor |
E6-ab-1 | 265-271 | cui:C0034493 | denotes | rabbit |
E7-ab-1 | 272-284 | cui:C0035286 | denotes | reticulocyte |
E8-ab-1 | 302-305 | cui:C0012854 | denotes | DNA |
T2 | 215-244 | PART_OF | denotes | human glucocorticoid receptor |
T3 | 297-301 | INTERACTS_WITH | denotes | bind |
E1-ab-2 | 316-326 | cui:C0040710 | denotes | translated |
E2-ab-2 | 327-330 | cui:C0020114 | denotes | hGR |
E3-ab-2 | 327-330 | cui:C0034809 | denotes | hGR |
E4-ab-2 | 358-364 | cui:C0302891 | denotes | native |
E5-ab-2 | 365-368 | cui:C0020114 | denotes | hGR |
E6-ab-2 | 365-368 | cui:C0034809 | denotes | hGR |
E7-ab-2 | 400-422 | cui:C0037506 | denotes | sodium dodecyl sulfate |
E8-ab-2 | 423-442 | cui:C0071500 | denotes | polyacrylamide gels |
E9-ab-2 | 444-457 | cui:C0597428 | denotes | sedimentation |
E10-ab-2 | 461-468 | cui:C0038636 | denotes | sucrose |
E11-ab-2 | 469-476 | cui:C0178587 | denotes | density |
E12-ab-2 | 477-486 | cui:C0439182 | denotes | gradients |
E13-ab-2 | 492-502 | cui:C0205332 | denotes | reactivity |
E14-ab-2 | 520-530 | cui:C0003241 | denotes | antibodies |
E15-ab-2 | 549-552 | cui:C0020114 | denotes | hGR |
E16-ab-2 | 549-552 | cui:C0034809 | denotes | hGR |
T4 | 327-330 | PART_OF | denotes | hGR |
T5 | 365-368 | PART_OF | denotes | hGR |
T6 | 531-540 | PRODUCES | denotes | generated |
T7 | 549-552 | PART_OF | denotes | hGR |
E1-ab-3 | 557-565 | cui:C0442796 | denotes | addition |
E2-ab-3 | 567-572 | cui:C0007634 | denotes | cell- |
E3-ab-3 | 589-592 | cui:C0020114 | denotes | hGR |
E4-ab-3 | 589-592 | cui:C0034809 | denotes | hGR |
E5-ab-3 | 628-642 | cui:C0017710 | denotes | glucocorticoid |
E6-ab-3 | 643-659 | cui:C0600508 | denotes | response element |
E7-ab-3 | 666-676 | cui:C0332256 | denotes | containing |
E8-ab-3 | 677-680 | cui:C0012854 | denotes | DNA |
E9-ab-3 | 681-690 | cui:C0486805 | denotes | fragments |
T8 | 589-592 | PART_OF | denotes | hGR |
E1-ab-4 | 703-708 | cui:C1510438 | denotes | assay |
E2-ab-4 | 709-715 | cui:C0449913 | denotes | system |
E3-ab-4 | 756-770 | cui:C1517880 | denotes | ligand binding |
E4-ab-4 | 794-805 | cui:C1148673 | denotes | DNA binding |
E5-ab-4 | 815-839 | cui:C0034809 | denotes | glucocorticoid receptors |
E1-ab-5 | 850-860 | cui:C0040710 | denotes | translated |
E2-ab-5 | 861-864 | cui:C0020114 | denotes | hGR |
E3-ab-5 | 861-864 | cui:C0034809 | denotes | hGR |
E4-ab-5 | 890-901 | cui:C1148673 | denotes | DNA binding |
E5-ab-5 | 925-939 | cui:C0017710 | denotes | glucocorticoid |
T9 | 861-864 | PART_OF | denotes | hGR |
E1-ab-6 | 941-950 | cui:C0087111 | denotes | Treatment |
E2-ab-6 | 956-969 | cui:C0011777 | denotes | dexamethasone |
E3-ab-6 | 996-1001 | cui:C0701303 | denotes | RU486 |
E4-ab-6 | 1009-1019 | cui:C1524062 | denotes | additional |
E5-ab-6 | 1020-1026 | cui:C1280500 | denotes | effect |
E6-ab-6 | 1034-1038 | cui:C0012854 | denotes | DNA- |
E7-ab-6 | 1038-1054 | cui:C0439155 | denotes | binding capacity |
E8-ab-6 | 1060-1068 | cui:C0597357 | denotes | receptor |
E9-ab-6 | 1069-1081 | cui:C1521827 | denotes | preparations |
T10 | 951-955 | USES | denotes | with |
T11 | 951-955 | USES | denotes | with |
E1-ab-7 | 1135-1143 | cui:C0442796 | denotes | addition |
E2-ab-7 | 1154-1160 | cui:C1167622 | denotes | ligand |
E3-ab-7 | 1178-1189 | cui:C0205195 | denotes | combination |
E4-ab-7 | 1213-1217 | cui:C1261552 | denotes | step |
E5-ab-7 | 1227-1238 | cui:C1148673 | denotes | DNA binding |
E6-ab-7 | 1242-1255 | cui:C0332232 | denotes | approximately |
E7-ab-7 | 1258-1262 | cui:C0332462 | denotes | fold |
E8-ab-7 | 1263-1267 | cui:C0205136 | denotes | over |
E9-ab-7 | 1281-1290 | cui:C1515877 | denotes | activated |
E10-ab-7 | 1302-1311 | cui:C0597357 | denotes | receptors |
E1-ab-8 | 1313-1320 | cui:C0243192 | denotes | Agonist |
E2-ab-8 | 1322-1335 | cui:C0011777 | denotes | dexamethasone |
E3-ab-8 | 1341-1349 | cui:C0750482 | denotes | slightly |
E4-ab-8 | 1355-1364 | cui:C1280500 | denotes | effective |
E5-ab-8 | 1368-1378 | cui:C0183683 | denotes | supporting |
E6-ab-8 | 1388-1399 | cui:C1148673 | denotes | DNA binding |
E7-ab-8 | 1417-1422 | cui:C0701303 | denotes | RU486 |
E1-ab-9 | 1425-1436 | cui:C1148673 | denotes | DNA binding |
E2-ab-9 | 1483-1491 | cui:C0442796 | denotes | addition |
E3-ab-9 | 1495-1511 | cui:C0074747 | denotes | sodium molybdate |
E4-ab-9 | 1519-1527 | cui:C0597357 | denotes | receptor |
E5-ab-9 | 1528-1540 | cui:C1521827 | denotes | preparations |
E6-ab-9 | 1548-1555 | cui:C0038317 | denotes | steroid |
E7-ab-9 | 1556-1564 | cui:C1524062 | denotes | addition |
E1-ab-10 | 1589-1597 | cui:C0442796 | denotes | Addition |
E2-ab-10 | 1622-1633 | cui:C1148673 | denotes | DNA binding |
E3-ab-10 | 1660-1672 | cui:C0058595 | denotes | DNA-receptor |
E4-ab-10 | 1673-1680 | cui:C0439855 | denotes | complex |
E5-ab-10 | 1681-1690 | cui:C1522492 | denotes | formation |
E6-ab-10 | 1694-1704 | cui:C0332453 | denotes | disruption |
E7-ab-10 | 1712-1721 | cui:C0439855 | denotes | complexes |
E1-ab-11 | 1727-1738 | cui:C0037791 | denotes | specificity |
E2-ab-11 | 1742-1753 | cui:C1148673 | denotes | DNA binding |
E3-ab-11 | 1757-1762 | cui:C0007634 | denotes | cell- |
E4-ab-11 | 1779-1782 | cui:C0020114 | denotes | hGR |
E5-ab-11 | 1779-1782 | cui:C0034809 | denotes | hGR |
E6-ab-11 | 1796-1803 | cui:C1517331 | denotes | further |
E7-ab-11 | 1807-1816 | cui:C0332128 | denotes | examining |
E8-ab-11 | 1821-1830 | cui:C0085732 | denotes | abilities |
E9-ab-11 | 1842-1846 | cui:C0012854 | denotes | DNAs |
E10-ab-11 | 1895-1898 | cui:C0017710 | denotes | GRE |
E11-ab-11 | 1895-1898 | cui:C0600508 | denotes | GRE |
E12-ab-11 | 1912-1937 | cui:C0024662 | denotes | mouse mammary tumor virus |
E13-ab-11 | 1938-1958 | cui:C0023978 | denotes | long terminal repeat |
T12 | 1779-1782 | PART_OF | denotes | hGR |
E1-ab-12 | 1960-1976 | cui:C0028953 | denotes | Oligonucleotides |
E2-ab-12 | 1992-2001 | cui:C0376298 | denotes | consensus |
E3-ab-12 | 2002-2005 | cui:C0017710 | denotes | GRE |
E4-ab-12 | 2002-2005 | cui:C0600508 | denotes | GRE |
E5-ab-12 | 2015-2019 | cui:C0205393 | denotes | most |
E6-ab-12 | 2020-2029 | cui:C0442799 | denotes | efficient |
E7-ab-12 | 2047-2056 | cui:C0486805 | denotes | fragments |
E8-ab-12 | 2068-2088 | cui:C0314642 | denotes | regulatory sequences |
E9-ab-12 | 2094-2108 | cui:C0017710 | denotes | glucocorticoid |
E10-ab-12 | 2121-2126 | cui:C0017337 | denotes | genes |
E11-ab-12 | 2141-2152 | cui:C0679932 | denotes | competitive |
E12-ab-12 | 2162-2168 | cui:C0205171 | denotes | single |
E13-ab-12 | 2178-2194 | cui:C0028953 | denotes | oligonucleotides |
E14-ab-12 | 2200-2206 | cui:C1299582 | denotes | unable |
E15-ab-12 | 2222-2247 | cui:C0024662 | denotes | mouse mammary tumor virus |
E16-ab-12 | 2248-2268 | cui:C0023978 | denotes | long terminal repeat |
E17-ab-12 | 2269-2280 | cui:C1148673 | denotes | DNA binding |
E18-ab-12 | 2309-2316 | cui:C0150312 | denotes | present |
E19-ab-12 | 2330-2334 | cui:C0205250 | denotes | high |
E20-ab-12 | 2335-2349 | cui:C0086045 | denotes | concentrations |
E1-ab-13 | 2366-2373 | cui:C0008972 | denotes | studies |
E2-ab-13 | 2388-2391 | cui:C0020114 | denotes | hGR |
E3-ab-13 | 2388-2391 | cui:C0034809 | denotes | hGR |
E4-ab-13 | 2407-2413 | cui:C0034493 | denotes | rabbit |
E5-ab-13 | 2414-2426 | cui:C0035286 | denotes | reticulocyte |
E6-ab-13 | 2456-2460 | cui:C0445247 | denotes | same |
E7-ab-13 | 2461-2471 | cui:C0871161 | denotes | properties |
E8-ab-13 | 2483-2486 | cui:C0017710 | denotes | GRE |
E9-ab-13 | 2483-2486 | cui:C0600508 | denotes | GRE |
E10-ab-13 | 2496-2507 | cui:C1148673 | denotes | DNA binding |
E11-ab-13 | 2522-2545 | cui:C0034809 | denotes | glucocorticoid receptor |
E12-ab-13 | 2546-2553 | cui:C0150312 | denotes | present |
E13-ab-13 | 2557-2566 | cui:C0010854 | denotes | cytosolic |
E14-ab-13 | 2567-2575 | cui:C1555707 | denotes | extracts |
E15-ab-13 | 2579-2594 | cui:C1512977 | denotes | mammalian cells |
E16-ab-13 | 2599-2606 | cui:C0040300 | denotes | tissues |
T13 | 2388-2391 | PART_OF | denotes | hGR |
E1-ab-14 | 2608-2620 | cui:C0871364 | denotes | Similarities |
E2-ab-14 | 2633-2640 | cui:C1280500 | denotes | effects |
E3-ab-14 | 2644-2657 | cui:C0011777 | denotes | dexamethasone |
E4-ab-14 | 2662-2667 | cui:C0701303 | denotes | RU486 |
E5-ab-14 | 2704-2714 | cui:C0871161 | denotes | properties |
E6-ab-14 | 2718-2723 | cui:C0701303 | denotes | RU486 |
E7-ab-14 | 2727-2730 | cui:C1518422 | denotes | not |
E8-ab-14 | 2762-2773 | cui:C1148673 | denotes | DNA binding |
R1 | E6-ti-1 | T1 | subjectOf | glucocorticoid receptor,human glucocorticoid receptor |
R2 | E5-ti-1 | T1 | objectOf | human,human glucocorticoid receptor |
R3 | E5-ab-1 | T2 | subjectOf | glucocorticoid receptor,human glucocorticoid receptor |
R4 | E4-ab-1 | T2 | objectOf | human,human glucocorticoid receptor |
R5 | E5-ab-1 | T3 | subjectOf | glucocorticoid receptor,bind |
R6 | E8-ab-1 | T3 | objectOf | DNA,bind |
R7 | E3-ab-2 | T4 | subjectOf | hGR,hGR |
R8 | E2-ab-2 | T4 | objectOf | hGR,hGR |
R9 | E6-ab-2 | T5 | subjectOf | hGR,hGR |
R10 | E5-ab-2 | T5 | objectOf | hGR,hGR |
R11 | E14-ab-2 | T6 | subjectOf | antibodies,generated |
R12 | E16-ab-2 | T6 | objectOf | hGR,generated |
R13 | E16-ab-2 | T7 | subjectOf | hGR,hGR |
R14 | E15-ab-2 | T7 | objectOf | hGR,hGR |
R15 | E4-ab-3 | T8 | subjectOf | hGR,hGR |
R16 | E3-ab-3 | T8 | objectOf | hGR,hGR |
R17 | E3-ab-5 | T9 | subjectOf | hGR,hGR |
R18 | E2-ab-5 | T9 | objectOf | hGR,hGR |
R19 | E1-ab-6 | T10 | subjectOf | Treatment,with |
R20 | E2-ab-6 | T10 | objectOf | dexamethasone,with |
R21 | E1-ab-6 | T11 | subjectOf | Treatment,with |
R22 | E3-ab-6 | T11 | objectOf | RU486,with |
R23 | E5-ab-11 | T12 | subjectOf | hGR,hGR |
R24 | E4-ab-11 | T12 | objectOf | hGR,hGR |
R25 | E3-ab-13 | T13 | subjectOf | hGR,hGR |
R26 | E2-ab-13 | T13 | objectOf | hGR,hGR |
pubmed-sentences-benchmark
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
S1 | 0-134 | Sentence | denotes | Evaluation of the role of ligand and thermal activation of specific DNA binding by in vitro synthesized human glucocorticoid receptor. |
S2 | 135-306 | Sentence | denotes | We have used a DNA-binding/immunoprecipitation assay to analyze the capacity of human glucocorticoid receptor (hGR), generated in rabbit reticulocyte lysates, to bind DNA. |
S3 | 307-553 | Sentence | denotes | In vitro translated hGR was indistinguishable from native hGR, as determined by migration on sodium dodecyl sulfate-polyacrylamide gels, sedimentation on sucrose density gradients, and reactivity with antipeptide antibodies generated against hGR. |
S4 | 554-691 | Sentence | denotes | In addition, cell-free synthesized hGR was capable of specific binding to glucocorticoid response element (GRE)-containing DNA fragments. |
S5 | 692-840 | Sentence | denotes | Using this assay system, we have evaluated the contributions of ligand binding and heat activation to DNA binding by these glucocorticoid receptors. |
S6 | 841-940 | Sentence | denotes | In vitro translated hGR was capable of selective DNA binding even in the absence of glucocorticoid. |
S7 | 941-1121 | Sentence | denotes | Treatment with dexamethasone or the antiglucocorticoid RU486 had no additional effect on the DNA-binding capacity when receptor preparations were maintained at 0 C (no activation). |
S8 | 1122-1312 | Sentence | denotes | In contrast, addition of either ligand or antagonist in combination with a heat activation step promoted DNA binding by approximately 3-fold over that of heat-activated unliganded receptors. |
S9 | 1313-1424 | Sentence | denotes | Agonist (dexamethasone) was slightly more effective in supporting specific DNA binding than antagonist (RU486). |
S10 | 1425-1588 | Sentence | denotes | DNA binding by in vitro synthesized GR was blocked by the addition of sodium molybdate to the receptor preparations before steroid addition and thermal activation. |
S11 | 1589-1722 | Sentence | denotes | Addition of KCl resulted in less DNA binding either due to blockage of DNA-receptor complex formation or disruption of the complexes. |
S12 | 1723-1959 | Sentence | denotes | The specificity of DNA binding by cell-free synthesized hGR was analyzed further by examining the abilities of various DNAs to compete for binding to a naturally occurring GRE found in the mouse mammary tumor virus-long terminal repeat. |
S13 | 1960-2350 | Sentence | denotes | Oligonucleotides containing the consensus GRE were the most efficient competitors, and fragments containing regulatory sequences from glucocorticoid-repressible genes were somewhat competitive, whereas single stranded oligonucleotides were unable to compete for mouse mammary tumor virus-long terminal repeat DNA binding, except when competitor was present at extremely high concentrations. |
S14 | 2351-2607 | Sentence | denotes | Together these studies indicate that hGR synthesized in rabbit reticulocyte lysates displays many of the same properties, including GRE-specific DNA binding, observed for glucocorticoid receptor present in cytosolic extracts of mammalian cells and tissues. |
S15 | 2608-2774 | Sentence | denotes | Similarities between the effects of dexamethasone and RU486 suggest that the antiglucocorticoid properties of RU486 do not occur at the level of specific DNA binding. |
genia-medco-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
C1 | 26-32 | NP | denotes | ligand |
C2 | 37-55 | NP | denotes | thermal activation |
C4 | 68-71 | NP | denotes | DNA |
C3 | 59-79 | NP | denotes | specific DNA binding |
C6 | 110-124 | NP | denotes | glucocorticoid |
C5 | 92-133 | NP | denotes | synthesized human glucocorticoid receptor |
C8 | 221-235 | NP | denotes | glucocorticoid |
C7 | 215-250 | NP | denotes | human glucocorticoid receptor (hGR) |
C9 | 265-292 | NP | denotes | rabbit reticulocyte lysates |
C10 | 302-305 | NP | denotes | DNA |
C11 | 316-330 | NP | denotes | translated hGR |
C12 | 358-368 | NP | denotes | native hGR |
C13 | 549-552 | NP | denotes | hGR |
C14 | 567-592 | NP | denotes | cell-free synthesized hGR |
C15 | 628-665 | NP | denotes | glucocorticoid response element (GRE) |
C16 | 775-790 | NP | denotes | heat activation |
C18 | 794-797 | NP | denotes | DNA |
C17 | 794-805 | NP | denotes | DNA binding |
C20 | 815-829 | NP | denotes | glucocorticoid |
C19 | 809-839 | NP | denotes | these glucocorticoid receptors |
C21 | 850-864 | NP | denotes | translated hGR |
C23 | 890-893 | NP | denotes | DNA |
C22 | 880-901 | NP | denotes | selective DNA binding |
C24 | 925-939 | NP | denotes | glucocorticoid |
C25 | 956-969 | NP | denotes | dexamethasone |
C26 | 973-1001 | NP | denotes | the antiglucocorticoid RU486 |
C27 | 1060-1081 | NP | denotes | receptor preparations |
C28 | 1154-1160 | NP | denotes | ligand |
C29 | 1195-1212 | NP | denotes | a heat activation |
C31 | 1227-1230 | NP | denotes | DNA |
C30 | 1227-1238 | NP | denotes | DNA binding |
C32 | 1268-1272 | NP | denotes | that |
C33 | 1313-1336 | NP | denotes | Agonist (dexamethasone) |
C35 | 1388-1391 | NP | denotes | DNA |
C34 | 1379-1399 | NP | denotes | specific DNA binding |
C36 | 1405-1423 | NP | denotes | antagonist (RU486) |
C38 | 1425-1428 | NP | denotes | DNA |
C37 | 1425-1436 | NP | denotes | DNA binding |
C39 | 1515-1540 | NP | denotes | the receptor preparations |
C40 | 1569-1587 | NP | denotes | thermal activation |
C42 | 1622-1625 | NP | denotes | DNA |
C41 | 1622-1633 | NP | denotes | DNA binding |
C44 | 1742-1745 | NP | denotes | DNA |
C43 | 1742-1753 | NP | denotes | DNA binding |
C45 | 1757-1782 | NP | denotes | cell-free synthesized hGR |
C46 | 1834-1846 | NP | denotes | various DNAs |
C47 | 1895-1898 | NP | denotes | GRE |
C48 | 1908-1958 | NP | denotes | the mouse mammary tumor virus-long terminal repeat |
C49 | 1960-1976 | NP | denotes | Oligonucleotides |
C50 | 1988-2005 | NP | denotes | the consensus GRE |
C51 | 2162-2194 | NP | denotes | single stranded oligonucleotides |
C52 | 2222-2268 | NP | denotes | mouse mammary tumor virus-long terminal repeat |
C54 | 2269-2272 | NP | denotes | DNA |
C53 | 2269-2280 | NP | denotes | DNA binding |
C55 | 2388-2391 | NP | denotes | hGR |
C56 | 2407-2434 | NP | denotes | rabbit reticulocyte lysates |
C58 | 2496-2499 | NP | denotes | DNA |
C57 | 2483-2507 | NP | denotes | GRE-specific DNA binding |
C60 | 2522-2536 | NP | denotes | glucocorticoid |
C59 | 2522-2545 | NP | denotes | glucocorticoid receptor |
C61 | 2644-2657 | NP | denotes | dexamethasone |
C62 | 2662-2667 | NP | denotes | RU486 |
C63 | 2718-2723 | NP | denotes | RU486 |
C65 | 2762-2765 | NP | denotes | DNA |
C64 | 2753-2773 | NP | denotes | specific DNA binding |
R1 | C8 | C6 | coref-ident | glucocorticoid,glucocorticoid |
R2 | C7 | C5 | coref-ident | human glucocorticoid receptor (hGR),synthesized human glucocorticoid receptor |
R3 | C10 | C4 | coref-ident | DNA,DNA |
R4 | C11 | C7 | coref-other | translated hGR,human glucocorticoid receptor (hGR) |
R5 | C12 | C11 | coref-other | native hGR,translated hGR |
R6 | C13 | C7 | coref-ident | hGR,human glucocorticoid receptor (hGR) |
R7 | C14 | C5 | coref-other | cell-free synthesized hGR,synthesized human glucocorticoid receptor |
R8 | C16 | C2 | coref-ident | heat activation,thermal activation |
R9 | C18 | C10 | coref-ident | DNA,DNA |
R10 | C17 | C3 | coref-ident | DNA binding,specific DNA binding |
R11 | C20 | C8 | coref-ident | glucocorticoid,glucocorticoid |
R12 | C19 | C14 | coref-ident | these glucocorticoid receptors,cell-free synthesized hGR |
R13 | C21 | C11 | coref-ident | translated hGR,translated hGR |
R14 | C23 | C18 | coref-ident | DNA,DNA |
R15 | C22 | C17 | coref-other | selective DNA binding,DNA binding |
R16 | C24 | C20 | coref-ident | glucocorticoid,glucocorticoid |
R17 | C28 | C1 | coref-ident | ligand,ligand |
R18 | C29 | C16 | coref-ident | a heat activation,heat activation |
R19 | C31 | C23 | coref-ident | DNA,DNA |
R20 | C30 | C22 | coref-ident | DNA binding,selective DNA binding |
R21 | C32 | C30 | coref-pron | that,DNA binding |
R22 | C33 | C25 | coref-ident | Agonist (dexamethasone),dexamethasone |
R23 | C35 | C31 | coref-ident | DNA,DNA |
R24 | C34 | C30 | coref-other | specific DNA binding,DNA binding |
R25 | C36 | C26 | coref-ident | antagonist (RU486),the antiglucocorticoid RU486 |
R26 | C38 | C35 | coref-ident | DNA,DNA |
R27 | C37 | C30 | coref-ident | DNA binding,DNA binding |
R28 | C39 | C27 | coref-ident | the receptor preparations,receptor preparations |
R29 | C40 | C29 | coref-ident | thermal activation,a heat activation |
R30 | C42 | C38 | coref-ident | DNA,DNA |
R31 | C41 | C37 | coref-ident | DNA binding,DNA binding |
R32 | C44 | C42 | coref-ident | DNA,DNA |
R33 | C43 | C41 | coref-ident | DNA binding,DNA binding |
R34 | C45 | C14 | coref-ident | cell-free synthesized hGR,cell-free synthesized hGR |
R35 | C46 | C44 | coref-ident | various DNAs,DNA |
R36 | C47 | C15 | coref-ident | GRE,glucocorticoid response element (GRE) |
R37 | C50 | C47 | coref-ident | the consensus GRE,GRE |
R38 | C51 | C49 | coref-other | single stranded oligonucleotides,Oligonucleotides |
R39 | C52 | C48 | coref-ident | mouse mammary tumor virus-long terminal repeat,the mouse mammary tumor virus-long terminal repeat |
R40 | C54 | C46 | coref-ident | DNA,various DNAs |
R41 | C53 | C43 | coref-ident | DNA binding,DNA binding |
R42 | C55 | C13 | coref-ident | hGR,hGR |
R43 | C56 | C9 | coref-ident | rabbit reticulocyte lysates,rabbit reticulocyte lysates |
R44 | C58 | C54 | coref-ident | DNA,DNA |
R45 | C57 | C53 | coref-other | GRE-specific DNA binding,DNA binding |
R46 | C60 | C24 | coref-ident | glucocorticoid,glucocorticoid |
R47 | C59 | C55 | coref-ident | glucocorticoid receptor,hGR |
R48 | C61 | C33 | coref-ident | dexamethasone,Agonist (dexamethasone) |
R49 | C62 | C36 | coref-ident | RU486,antagonist (RU486) |
R50 | C63 | C62 | coref-ident | RU486,RU486 |
R51 | C65 | C58 | coref-ident | DNA,DNA |
R52 | C64 | C57 | coref-ident | specific DNA binding,GRE-specific DNA binding |
GENIAcorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 26-32 | other_name | denotes | ligand |
T2 | 37-55 | other_name | denotes | thermal activation |
T3 | 59-79 | other_name | denotes | specific DNA binding |
T4 | 83-133 | protein_molecule | denotes | in vitro synthesized human glucocorticoid receptor |
T5 | 150-187 | other_name | denotes | DNA-binding/immunoprecipitation assay |
T6 | 215-244 | protein_molecule | denotes | human glucocorticoid receptor |
T7 | 246-249 | protein_molecule | denotes | hGR |
T8 | 265-292 | other_name | denotes | rabbit reticulocyte lysates |
T9 | 307-330 | protein_molecule | denotes | In vitro translated hGR |
T10 | 358-368 | protein_family_or_group | denotes | native hGR |
T11 | 400-442 | other_name | denotes | sodium dodecyl sulfate-polyacrylamide gels |
T12 | 444-457 | other_name | denotes | sedimentation |
T13 | 461-486 | other_name | denotes | sucrose density gradients |
T14 | 508-530 | protein_family_or_group | denotes | antipeptide antibodies |
T15 | 549-552 | protein_molecule | denotes | hGR |
T16 | 567-592 | protein_molecule | denotes | cell-free synthesized hGR |
T17 | 628-659 | DNA_domain_or_region | denotes | glucocorticoid response element |
T18 | 661-664 | DNA_domain_or_region | denotes | GRE |
T19 | 703-715 | other_name | denotes | assay system |
T20 | 794-805 | other_name | denotes | DNA binding |
T21 | 815-839 | protein_family_or_group | denotes | glucocorticoid receptors |
T22 | 841-864 | protein_molecule | denotes | In vitro translated hGR |
T23 | 925-939 | lipid | denotes | glucocorticoid |
T24 | 956-969 | lipid | denotes | dexamethasone |
T25 | 977-1001 | other_organic_compound | denotes | antiglucocorticoid RU486 |
T26 | 1034-1054 | other_name | denotes | DNA-binding capacity |
T27 | 1060-1081 | other_name | denotes | receptor preparations |
T28 | 1227-1238 | other_name | denotes | DNA binding |
T29 | 1291-1311 | protein_family_or_group | denotes | unliganded receptors |
T30 | 1322-1335 | lipid | denotes | dexamethasone |
T31 | 1379-1399 | other_name | denotes | specific DNA binding |
T32 | 1417-1422 | other_organic_compound | denotes | RU486 |
T33 | 1440-1463 | protein_family_or_group | denotes | in vitro synthesized GR |
T34 | 1519-1540 | other_name | denotes | receptor preparations |
T35 | 1548-1564 | other_name | denotes | steroid addition |
T36 | 1569-1587 | other_name | denotes | thermal activation |
T37 | 1601-1604 | inorganic | denotes | KCl |
T38 | 1622-1633 | other_name | denotes | DNA binding |
T39 | 1660-1664 | other_name | denotes | DNA- |
T40 | 1664-1680 | protein_complex | denotes | receptor complex |
T41 | 1742-1753 | other_name | denotes | DNA binding |
T42 | 1757-1782 | protein_family_or_group | denotes | cell-free synthesized hGR |
T43 | 1834-1846 | DNA_family_or_group | denotes | various DNAs |
T44 | 1895-1898 | DNA_domain_or_region | denotes | GRE |
T45 | 1912-1958 | DNA_domain_or_region | denotes | mouse mammary tumor virus-long terminal repeat |
T46 | 1992-2001 | DNA_domain_or_region | denotes | consensus |
T47 | 2002-2005 | DNA_domain_or_region | denotes | GRE |
T48 | 2068-2088 | DNA_domain_or_region | denotes | regulatory sequences |
T49 | 2094-2108 | lipid | denotes | glucocorticoid |
T50 | 2178-2194 | polynucleotide | denotes | oligonucleotides |
T51 | 2222-2268 | DNA_domain_or_region | denotes | mouse mammary tumor virus-long terminal repeat |
T52 | 2269-2280 | other_name | denotes | DNA binding |
T53 | 2388-2391 | protein_family_or_group | denotes | hGR |
T54 | 2483-2486 | DNA_domain_or_region | denotes | GRE |
T55 | 2486-2495 | other_name | denotes | -specific |
T56 | 2496-2507 | other_name | denotes | DNA binding |
T57 | 2522-2545 | protein_family_or_group | denotes | glucocorticoid receptor |
T58 | 2557-2575 | cell_component | denotes | cytosolic extracts |
T59 | 2579-2594 | cell_type | denotes | mammalian cells |
T60 | 2599-2606 | tissue | denotes | tissues |
T61 | 2644-2657 | lipid | denotes | dexamethasone |
T62 | 2662-2667 | other_organic_compound | denotes | RU486 |
T63 | 2685-2714 | other_name | denotes | antiglucocorticoid properties |
T64 | 2718-2723 | other_organic_compound | denotes | RU486 |
T65 | 2753-2761 | other_name | denotes | specific |
T66 | 2762-2773 | other_name | denotes | DNA binding |
metamap-sample
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 2389-2392 | C0086418 | denotes | GR |
T2 | 1780-1783 | C0086418 | denotes | GR |
T3 | 862-865 | C0086418 | denotes | GR |
T4 | 590-593 | C0086418 | denotes | GR |
T5 | 216-221 | C0086418 | denotes | uman |
T6 | 105-110 | C0086418 | denotes | uman |
T7 | 2389-2392 | C0034809 | denotes | GR |
T8 | 1780-1783 | C0034809 | denotes | GR |
T9 | 862-865 | C0034809 | denotes | GR |
T10 | 590-593 | C0034809 | denotes | GR |
T11 | 222-245 | C0034809 | denotes | lucocorticoid receptor |
T12 | 111-134 | C0034809 | denotes | lucocorticoid receptor. |
T13 | 1155-1161 | C0023688 | denotes | igand |
T14 | 27-33 | C0023688 | denotes | igand |
T15 | 1441-1449 | C0021135 | denotes | n vitro |
T16 | 842-850 | C0021135 | denotes | n vitro |
T17 | 308-316 | C0021135 | denotes | n vitro |
T18 | 84-92 | C0021135 | denotes | n vitro |
T19 | 2484-2487 | C0017710 | denotes | RE- |
T20 | 2003-2006 | C0017710 | denotes | RE |
T21 | 2095-2109 | C0017710 | denotes | lucocorticoid- |
T22 | 1896-1899 | C0017710 | denotes | RE |
T23 | 926-940 | C0017710 | denotes | lucocorticoid. |
T24 | 629-643 | C0017710 | denotes | lucocorticoid |
T25 | 2484-2487 | C0600508 | denotes | RE- |
T26 | 2003-2006 | C0600508 | denotes | RE |
T27 | 1896-1899 | C0600508 | denotes | RE |
T28 | 644-660 | C0600508 | denotes | esponse element |
T29 | 1-11 | C1261322 | denotes | valuation |
T30 | 2393-2404 | C1883254 | denotes | ynthesized |
T31 | 1768-1779 | C1883254 | denotes | ynthesized |
T32 | 1450-1461 | C1883254 | denotes | ynthesized |
T33 | 578-589 | C1883254 | denotes | ynthesized |
T34 | 93-104 | C1883254 | denotes | ynthesized |
T35 | 2754-2762 | C0205369 | denotes | pecific |
T36 | 2488-2496 | C0205369 | denotes | pecific |
T37 | 1380-1388 | C0205369 | denotes | pecific |
T38 | 609-617 | C0205369 | denotes | pecific |
T39 | 60-68 | C0205369 | denotes | pecific |
T40 | 19-23 | C1705810 | denotes | ole |
T41 | 1418-1423 | C0701303 | denotes | U486) |
T42 | 997-1002 | C0701303 | denotes | U486 |
T43 | 2645-2658 | C0011777 | denotes | examethasone |
T44 | 1323-1336 | C0011777 | denotes | examethasone) |
T45 | 957-970 | C0011777 | denotes | examethasone |
T46 | 2497-2508 | C1148673 | denotes | NA binding, |
T47 | 2270-2281 | C1148673 | denotes | NA binding, |
T48 | 1743-1754 | C1148673 | denotes | NA binding |
T49 | 1623-1634 | C1148673 | denotes | NA binding |
T50 | 1426-1437 | C1148673 | denotes | NA binding |
T51 | 1389-1400 | C1148673 | denotes | NA binding |
T52 | 1228-1239 | C1148673 | denotes | NA binding |
T53 | 1035-1046 | C1148673 | denotes | NA-binding |
T54 | 891-902 | C1148673 | denotes | NA binding |
T55 | 795-806 | C1148673 | denotes | NA binding |
T56 | 2408-2414 | C0034493 | denotes | abbit |
T57 | 266-272 | C0034493 | denotes | abbit |
T58 | 2223-2248 | C0024662 | denotes | ouse mammary tumor virus- |
T59 | 1913-1938 | C0024662 | denotes | ouse mammary tumor virus- |
T60 | 2249-2269 | C0023978 | denotes | ong terminal repeat |
T61 | 1939-1959 | C0023978 | denotes | ong terminal repeat. |
T62 | 2415-2427 | C0035286 | denotes | eticulocyte |
T63 | 273-285 | C0035286 | denotes | eticulocyte |
T64 | 851-861 | C0040710 | denotes | ranslated |
T65 | 317-327 | C0040710 | denotes | ranslated |
T66 | 1843-1847 | C0012854 | denotes | NAs |
T67 | 1035-1038 | C0012854 | denotes | NA- |
T68 | 303-306 | C0012854 | denotes | NA. |
T69 | 1961-1977 | C0028953 | denotes | ligonucleotides |
T70 | 2179-2195 | C0028953 | denotes | ligonucleotides |
T71 | 401-423 | C0037506 | denotes | odium dodecyl sulfate- |
T72 | 149-154 | C0000702 | denotes | DNA- |
T73 | 521-531 | C0003241 | denotes | ntibodies |
T74 | 1590-1598 | C1883712 | denotes | ddition |
T75 | 1136-1144 | C1883712 | denotes | ddition |
T76 | 558-566 | C1883712 | denotes | ddition, |
T77 | 1578-1588 | C1879547 | denotes | ctivation. |
T78 | 1282-1290 | C1879547 | denotes | ctivated |
T79 | 1203-1212 | C1879547 | denotes | ctivation |
T80 | 1110-1120 | C1879547 | denotes | ctivation) |
T81 | 781-791 | C1879547 | denotes | ctivation |
T82 | 2080-2089 | C0162326 | denotes | equences |
T83 | 2558-2567 | C1383501 | denotes | ytosolic |
T84 | 1993-2002 | C0376298 | denotes | onsensus |
T85 | 462-469 | C0038636 | denotes | ucrose |
T86 | 1863-1870 | C1167622 | denotes | inding |
T87 | 618-625 | C1167622 | denotes | inding |
T88 | 155-162 | C1167622 | denotes | inding/ |
T89 | 298-302 | C1167622 | denotes | ind |
T90 | 726-735 | C0220825 | denotes | valuated |
T91 | 163-182 | C0021069 | denotes | mmunoprecipitation |
T92 | 424-443 | C0071500 | denotes | olyacrylamide gels, |
T93 | 1496-1512 | C0074747 | denotes | odium molybdate |
T94 | 1822-1831 | C0085732 | denotes | bilities |
T95 | 667-676 | C2700400 | denotes | ontaining |
T96 | 2547-2554 | C0150312 | denotes | resent |
T97 | 2310-2317 | C0150312 | denotes | resent |
T98 | 1900-1905 | C0150312 | denotes | ound |
T99 | 1520-1527 | C0597357 | denotes | eceptor |
T100 | 1303-1312 | C0597357 | denotes | eceptors. |
T101 | 1061-1069 | C0597357 | denotes | eceptor |
T102 | 776-780 | C0018837 | denotes | eat |
T103 | 1406-1416 | C0231491 | denotes | ntagonist |
T104 | 1165-1175 | C0231491 | denotes | ntagonist |
T105 | 2732-2737 | C2745955 | denotes | ccur |
T106 | 1886-1895 | C2745955 | denotes | ccurring |
T107 | 704-709 | C1510438 | denotes | ssay |
T108 | 183-188 | C1510438 | denotes | ssay |
T109 | 1529-1541 | C1521827 | denotes | reparations |
T110 | 1070-1082 | C1521827 | denotes | reparations |
T111 | 532-541 | C3146294 | denotes | enerated |
T112 | 253-262 | C3146294 | denotes | enerated |
T113 | 2705-2715 | C0871161 | denotes | roperties |
T114 | 2462-2472 | C0871161 | denotes | roperties, |
T115 | 2428-2435 | C1881488 | denotes | ysates |
T116 | 286-293 | C1881488 | denotes | ysates, |
T117 | 870-877 | C2698977 | denotes | apable |
T118 | 598-605 | C2698977 | denotes | apable |
T119 | 1047-1054 | C1516240 | denotes | apacity |
T120 | 204-212 | C1516240 | denotes | apacity |
T121 | 1758-1767 | C1183428 | denotes | ell-free |
T122 | 568-577 | C1183428 | denotes | ell-free |
T123 | 1763-1767 | C1996904 | denotes | ree |
T124 | 573-577 | C1996904 | denotes | ree |
T125 | 1549-1556 | C0038317 | denotes | teroid |
T126 | 915-922 | C0332197 | denotes | bsence |
T127 | 1314-1321 | C2987634 | denotes | gonist |
T128 | 1788-1796 | C0936012 | denotes | nalyzed |
T129 | 1649-1657 | C1706968 | denotes | lockage |
T130 | 2600-2607 | C0040300 | denotes | issues. |
T131 | 1126-1134 | C1979874 | denotes | ontrast, |
T132 | 2436-2444 | C0870432 | denotes | isplays |
T133 | 2048-2057 | C0332255 | denotes | ragments |
T134 | 2474-2483 | C0332257 | denotes | ncluding |
T135 | 2728-2731 | C1518422 | denotes | ot |
T136 | 2367-2373 | C0947630 | denotes | tudies |
T137 | 2352-2360 | C1883357 | denotes | ogether |
T138 | 693-698 | C1524063 | denotes | sing |
T139 | 144-148 | C1273517 | denotes | sed |
T140 | 2669-2676 | C1705535 | denotes | uggest |
T141 | 2580-2595 | C1512977 | denotes | ammalian cells |
T142 | 710-716 | C0449913 | denotes | ystem, |
T143 | 2201-2207 | C1299582 | denotes | nable |
T144 | 2142-2153 | C0679932 | denotes | ompetitive, |
T145 | 678-691 | C0684192 | denotes | NA fragments. |
T146 | 2568-2576 | C2828366 | denotes | xtracts |
T147 | 1259-1263 | C0332462 | denotes | old |
T148 | 1808-1817 | C0332128 | denotes | xamining |
T149 | 1797-1804 | C1517331 | denotes | urther |
T150 | 942-951 | C0087111 | denotes | reatment |
T151 | 388-397 | C1533574 | denotes | igration |
T152 | 1695-1705 | C0332453 | denotes | isruption |
T153 | 1088-1098 | C1314677 | denotes | aintained |
T154 | 1728-1739 | C1511884 | denotes | pecificity |
T155 | 2445-2449 | C0439064 | denotes | any |
T156 | 2510-2518 | C1441672 | denotes | bserved |
T157 | 2457-2461 | C0445247 | denotes | ame |
T158 | 445-458 | C1384604 | denotes | edimentation |
T159 | 1469-1476 | C0332206 | denotes | locked |
T160 | 2745-2750 | C0456079 | denotes | evel |
T161 | 1356-1365 | C1704419 | denotes | ffective |
T162 | 740-753 | C1880177 | denotes | ontributions |
T163 | 1606-1614 | C1274040 | denotes | esulted |
T164 | 2609-2621 | C2348205 | denotes | imilarities |
T165 | 493-503 | C0205332 | denotes | eactivity |
T166 | 2163-2178 | C1979975 | denotes | ingle stranded |
T167 | 2133-2140 | C2984079 | denotes | omewhat |
T168 | 1665-1680 | C1523873 | denotes | eceptor complex |
T169 | 1243-1256 | C0332232 | denotes | pproximately |
T170 | 2021-2030 | C0442799 | denotes | fficient |
T171 | 2016-2020 | C0205393 | denotes | ost |
T172 | 757-771 | C1517880 | denotes | igand binding |
T173 | 1214-1218 | C1704379 | denotes | tep |
T174 | 1179-1190 | C1947911 | denotes | ombination |
T175 | 1039-1054 | C0439155 | denotes | inding capacity |
T176 | 1713-1722 | C1704241 | denotes | omplexes. |
T177 | 1219-1227 | C0033414 | denotes | romoted |
T178 | 2331-2335 | C1299351 | denotes | igh |
T179 | 478-487 | C0812409 | denotes | radients, |
T180 | 2336-2350 | C0086045 | denotes | oncentrations. |
T181 | 470-477 | C0178587 | denotes | ensity |
T182 | 2634-2641 | C1280500 | denotes | ffects |
T183 | 359-365 | C0302891 | denotes | ative |
T184 | 1835-1842 | C0440102 | denotes | arious |
T185 | 1462-1464 | C1552950 | denotes | R |
T186 | 1010-1020 | C1524062 | denotes | dditional |
T187 | 1342-1350 | C0750482 | denotes | lightly |
T188 | 1369-1379 | C0183683 | denotes | upporting |