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PubMed:19389916 JSONTXT

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PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 310-511 DRI_Background denotes Understanding what influences the serum activity of these enzymes as well as the sources of these enzymes is important to interpreting the significance of alterations in enzyme activity during disease.
T2 512-605 DRI_Outcome denotes This article demonstrates that in the mouse and human the predominant XylT in serum is XylT2.
T3 782-924 DRI_Outcome denotes In addition, the data from Xylt2 knock-out mice and mice with liver neoplasia show that liver is a significant source of serum XylT2 activity.
T4 925-1088 DRI_Outcome denotes The data presented suggest that serum XylT levels may be an informative biomarker in patients who suffer from diseases affecting platelet and/or liver homeostasis.

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 850-859 DiseaseOrPhenotypicFeature denotes neoplasia 0005070

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 757-762 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T2 757-762 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T3 844-849 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T4 870-875 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T5 1070-1075 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-168 Sentence denotes Xylosyltransferase II is a significant contributor of circulating xylosyltransferase levels and platelets constitute an important source of xylosyltransferase in serum.
TextSentencer_T2 169-309 Sentence denotes Circulating glycosyltransferases including xylosyltransferases I (XylT1) and II (XylT2) are potential serum biomarkers for various diseases.
TextSentencer_T3 310-511 Sentence denotes Understanding what influences the serum activity of these enzymes as well as the sources of these enzymes is important to interpreting the significance of alterations in enzyme activity during disease.
TextSentencer_T4 512-605 Sentence denotes This article demonstrates that in the mouse and human the predominant XylT in serum is XylT2.
TextSentencer_T5 606-781 Sentence denotes Furthermore, that total XylT levels in human serum are approximately 200% higher than those in plasma due in part to XylT released by platelets during blood clotting in vitro.
TextSentencer_T6 782-924 Sentence denotes In addition, the data from Xylt2 knock-out mice and mice with liver neoplasia show that liver is a significant source of serum XylT2 activity.
TextSentencer_T7 925-1088 Sentence denotes The data presented suggest that serum XylT levels may be an informative biomarker in patients who suffer from diseases affecting platelet and/or liver homeostasis.
T1 0-168 Sentence denotes Xylosyltransferase II is a significant contributor of circulating xylosyltransferase levels and platelets constitute an important source of xylosyltransferase in serum.
T2 169-309 Sentence denotes Circulating glycosyltransferases including xylosyltransferases I (XylT1) and II (XylT2) are potential serum biomarkers for various diseases.
T3 310-511 Sentence denotes Understanding what influences the serum activity of these enzymes as well as the sources of these enzymes is important to interpreting the significance of alterations in enzyme activity during disease.
T4 512-605 Sentence denotes This article demonstrates that in the mouse and human the predominant XylT in serum is XylT2.
T5 606-781 Sentence denotes Furthermore, that total XylT levels in human serum are approximately 200% higher than those in plasma due in part to XylT released by platelets during blood clotting in vitro.
T6 782-924 Sentence denotes In addition, the data from Xylt2 knock-out mice and mice with liver neoplasia show that liver is a significant source of serum XylT2 activity.
T7 925-1088 Sentence denotes The data presented suggest that serum XylT levels may be an informative biomarker in patients who suffer from diseases affecting platelet and/or liver homeostasis.
T1 0-168 Sentence denotes Xylosyltransferase II is a significant contributor of circulating xylosyltransferase levels and platelets constitute an important source of xylosyltransferase in serum.
T2 169-309 Sentence denotes Circulating glycosyltransferases including xylosyltransferases I (XylT1) and II (XylT2) are potential serum biomarkers for various diseases.
T3 310-511 Sentence denotes Understanding what influences the serum activity of these enzymes as well as the sources of these enzymes is important to interpreting the significance of alterations in enzyme activity during disease.
T4 512-605 Sentence denotes This article demonstrates that in the mouse and human the predominant XylT in serum is XylT2.
T5 606-781 Sentence denotes Furthermore, that total XylT levels in human serum are approximately 200% higher than those in plasma due in part to XylT released by platelets during blood clotting in vitro.
T6 782-924 Sentence denotes In addition, the data from Xylt2 knock-out mice and mice with liver neoplasia show that liver is a significant source of serum XylT2 activity.
T7 925-1088 Sentence denotes The data presented suggest that serum XylT levels may be an informative biomarker in patients who suffer from diseases affecting platelet and/or liver homeostasis.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 809-814 gene:64132 denotes Xylt2
T1 850-859 disease:C0027651 denotes neoplasia
T2 809-814 gene:64132 denotes Xylt2
T3 850-859 disease:C1882062 denotes neoplasia
T4 909-914 gene:64132 denotes XylT2
T5 850-859 disease:C0027651 denotes neoplasia
T6 909-914 gene:64132 denotes XylT2
T7 850-859 disease:C1882062 denotes neoplasia
R1 T0 T1 associated_with Xylt2,neoplasia
R2 T2 T3 associated_with Xylt2,neoplasia
R3 T4 T5 associated_with XylT2,neoplasia
R4 T6 T7 associated_with XylT2,neoplasia

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 96-105 FMAID:62851 denotes platelets
_T2 96-105 FMAID:167145 denotes platelets
_T3 162-167 FMAID:167330 denotes serum
_T4 271-276 FMAID:167330 denotes serum
_T5 344-349 FMAID:167330 denotes serum
_T6 590-595 FMAID:167330 denotes serum
_T7 651-656 FMAID:167330 denotes serum
_T8 701-707 FMAID:162307 denotes plasma
_T9 740-749 FMAID:167145 denotes platelets
_T10 740-749 FMAID:62851 denotes platelets
_T11 757-762 FMAID:256053 denotes blood
_T12 844-849 FMAID:93672 denotes liver
_T13 844-849 FMAID:7197 denotes liver
_T14 870-875 FMAID:7197 denotes liver
_T15 870-875 FMAID:93672 denotes liver
_T16 903-908 FMAID:167330 denotes serum
_T17 957-962 FMAID:167330 denotes serum
_T18 1054-1062 FMAID:167145 denotes platelet
_T19 1054-1062 FMAID:62851 denotes platelet
_T20 1070-1075 FMAID:7197 denotes liver
_T21 1070-1075 FMAID:93672 denotes liver

uniprot-human

Id Subject Object Predicate Lexical cue
T1 0-21 http://www.uniprot.org/uniprot/Q9H1B5 denotes Xylosyltransferase II

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 0-21 http://www.uniprot.org/uniprot/Q9EPL0 denotes Xylosyltransferase II
T2 809-814 http://www.uniprot.org/uniprot/Q9EPL0 denotes Xylt2

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 850-859 http://purl.bioontology.org/ontology/NCBITAXON/217470 denotes neoplasia

GO-BP

Id Subject Object Predicate Lexical cue
T1 350-375 http://purl.obolibrary.org/obo/GO_0003824 denotes activity of these enzymes
T2 480-495 http://purl.obolibrary.org/obo/GO_0003824 denotes enzyme activity
T3 757-771 http://purl.obolibrary.org/obo/GO_0007596 denotes blood clotting
T4 763-771 http://purl.obolibrary.org/obo/GO_0050817 denotes clotting
T5 1076-1087 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T6 1076-1087 http://purl.obolibrary.org/obo/GO_0033484 denotes homeostasis

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 162-167 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2 271-276 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T3 344-349 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T4 590-595 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T5 651-656 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T6 903-908 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T7 957-962 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T8 757-762 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T9 757-771 http://purl.obolibrary.org/obo/UBERON_0010210 denotes blood clotting
T10 844-849 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T11 870-875 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T12 1070-1075 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 757-762 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T2 757-762 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T3 844-849 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T4 870-875 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T5 1070-1075 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 844-849 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T2 870-875 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 1070-1075 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T4 757-762 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T5 162-167 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T6 271-276 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T7 344-349 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T8 590-595 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T9 651-656 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T10 903-908 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T11 957-962 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T12 757-771 http://purl.obolibrary.org/obo/UBERON_0010210 denotes blood clotting

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 757-762 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T3 844-849 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T4 870-875 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T5 1070-1075 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 850-859 Phenotype denotes neoplasia HP:0002664

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 850-859 Disease denotes neoplasia http://purl.obolibrary.org/obo/MONDO_0005070

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 550-555 OrganismTaxon denotes mouse 10088|10090
T3 560-565 OrganismTaxon denotes human 9606
T4 645-650 OrganismTaxon denotes human 9606
T5 825-829 OrganismTaxon denotes mice 10088
T6 834-838 OrganismTaxon denotes mice 10088

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 96-105 Body_part denotes platelets http://purl.obolibrary.org/obo/CL_0000233
T2 701-707 Body_part denotes plasma http://purl.obolibrary.org/obo/UBERON_0001969
T3 740-749 Body_part denotes platelets http://purl.obolibrary.org/obo/CL_0000233
T4 757-762 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T5 844-849 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T6 870-875 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T7 1054-1062 Body_part denotes platelet http://purl.obolibrary.org/obo/CL_0000233
T8 1070-1075 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 96-105 Cell denotes platelets http://purl.obolibrary.org/obo/CL:0000233
T2 740-749 Cell denotes platelets http://purl.obolibrary.org/obo/CL:0000233
T3 1054-1062 Cell denotes platelet http://purl.obolibrary.org/obo/CL:0000233