PubMed:19346865
Annnotations
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-177 | Sentence | denotes | Reversible inferior colliculus lesion in metronidazole-induced encephalopathy: magnetic resonance findings on diffusion-weighted and fluid attenuated inversion recovery imaging. |
T2 | 178-188 | Sentence | denotes | OBJECTIVE: |
T3 | 189-393 | Sentence | denotes | This is to present reversible inferior colliculus lesions in metronidazole-induced encephalopathy, to focus on the diffusion-weighted imaging (DWI) and fluid attenuated inversion recovery (FLAIR) imaging. |
T4 | 394-416 | Sentence | denotes | MATERIALS AND METHODS: |
T10 | 1249-1257 | Sentence | denotes | RESULTS: |
T5 | 417-573 | Sentence | denotes | From November 2005 to September 2007, 8 patients (5 men and 3 women) were diagnosed as having metronidazole-induced encephalopathy (age range; 43-78 years). |
T6 | 574-706 | Sentence | denotes | They had been taking metronidazole (total dosage, 45-120 g; duration, 30 days to 2 months) to treat the infection in various organs. |
T7 | 707-905 | Sentence | denotes | Initial brain magnetic resonance imaging (MRI) were obtained after the hospitalization, including DWI (8/8), apparent diffusion coefficient (ADC) map (4/8), FLAIR (7/8), and T2-weighted image (8/8). |
T8 | 906-1028 | Sentence | denotes | Follow-up MRIs were performed on 5 patients from third to 14th days after discontinuation of metronidazole administration. |
T9 | 1029-1248 | Sentence | denotes | Findings of initial and follow-up MRIs were retrospectively evaluated by 2 neuroradiologists by consensus, to analyze the presence of abnormal signal intensities, their locations, and signal changes on follow-up images. |
T11 | 1258-1500 | Sentence | denotes | Initial MRIs showed abnormal high signal intensities on DWI and FLAIR (or T2-weighted image) at the dentate nucleus (8/8), inferior colliculus (6/8), corpus callosum (2/8), pons (2/8), medulla (1/8), and bilateral cerebral white matter (1/8). |
T12 | 1501-1705 | Sentence | denotes | High-signal intensity lesions on DWI tended to show low signal intensity on ADC map (3/4), but in one patient, high signal intensity was shown at bilateral dentate nuclei on not only DWI but also ADC map. |
T13 | 1706-1895 | Sentence | denotes | All the lesions in dentate, inferior colliculus, pons, and medullas had been resolved completely on follow-up MRIs in 5 patients, but in 1 patient of them, corpus callosal lesion persisted. |
T14 | 1896-1908 | Sentence | denotes | CONCLUSIONS: |
T15 | 1909-2072 | Sentence | denotes | Reversible inferior colliculus lesions could be considered as the characteristic for metronidazole-induced encephalopathy, next to the dentate nucleus involvement. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
5946 | 11-37 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesion | MESH:D001927 |
5947 | 41-54 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5948 | 63-77 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | MESH:D001927 |
5949 | 219-246 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | MESH:D001927 |
5950 | 250-263 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5951 | 272-286 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | MESH:D001927 |
5952 | 457-465 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
5953 | 469-472 | OrganismTaxon | denotes | men | NCBITaxon:9606 |
5954 | 479-484 | OrganismTaxon | denotes | women | NCBITaxon:9606 |
5955 | 511-524 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5956 | 533-547 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | MESH:D001927 |
5957 | 595-608 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5958 | 678-687 | DiseaseOrPhenotypicFeature | denotes | infection | MESH:D007239 |
5959 | 941-949 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
5960 | 999-1012 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5961 | 1603-1610 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
5962 | 1826-1834 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
5963 | 1845-1852 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
5964 | 1869-1884 | DiseaseOrPhenotypicFeature | denotes | callosal lesion | MESH:D001927 |
5965 | 1920-1947 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | MESH:D001927 |
5966 | 1994-2007 | ChemicalEntity | denotes | metronidazole | MESH:D008795 |
5967 | 2016-2030 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | MESH:D001927 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 1472-1480 | DiseaseOrPhenotypicFeature | denotes | cerebral | 0002645 |
T2 | 1792-1802 | DiseaseOrPhenotypicFeature | denotes | completely | 0700063 |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 31-37 | GeneOrGeneProduct | denotes | lesion |
T2 | 55-62 | GeneOrGeneProduct | denotes | induced |
T3 | 98-106 | GeneOrGeneProduct | denotes | findings |
T4 | 139-149 | GeneOrGeneProduct | denotes | attenuated |
T5 | 239-246 | GeneOrGeneProduct | denotes | lesions |
T6 | 264-271 | GeneOrGeneProduct | denotes | induced |
T7 | 347-357 | GeneOrGeneProduct | denotes | attenuated |
T8 | 404-415 | GeneOrGeneProduct | denotes | AND METHODS |
T9 | 473-478 | GeneOrGeneProduct | denotes | and 3 |
T10 | 525-532 | GeneOrGeneProduct | denotes | induced |
T11 | 553-558 | GeneOrGeneProduct | denotes | range |
T12 | 566-571 | GeneOrGeneProduct | denotes | years |
T13 | 610-615 | GeneOrGeneProduct | denotes | total |
T14 | 707-714 | GeneOrGeneProduct | denotes | Initial |
T15 | 715-720 | GeneOrGeneProduct | denotes | brain |
T16 | 848-851 | GeneOrGeneProduct | denotes | ADC |
T17 | 881-883 | GeneOrGeneProduct | denotes | T2 |
T18 | 1029-1037 | GeneOrGeneProduct | denotes | Findings |
T19 | 1041-1048 | GeneOrGeneProduct | denotes | initial |
T20 | 1258-1265 | GeneOrGeneProduct | denotes | Initial |
T21 | 1287-1291 | GeneOrGeneProduct | denotes | high |
T22 | 1332-1334 | GeneOrGeneProduct | denotes | T2 |
T23 | 1366-1373 | GeneOrGeneProduct | denotes | nucleus |
T24 | 1431-1435 | GeneOrGeneProduct | denotes | pons |
T25 | 1481-1486 | GeneOrGeneProduct | denotes | white |
T26 | 1501-1505 | GeneOrGeneProduct | denotes | High |
T27 | 1523-1530 | GeneOrGeneProduct | denotes | lesions |
T28 | 1538-1544 | GeneOrGeneProduct | denotes | tended |
T29 | 1577-1580 | GeneOrGeneProduct | denotes | ADC |
T30 | 1581-1590 | GeneOrGeneProduct | denotes | map (3/4) |
T31 | 1612-1616 | GeneOrGeneProduct | denotes | high |
T32 | 1697-1700 | GeneOrGeneProduct | denotes | ADC |
T33 | 1706-1709 | GeneOrGeneProduct | denotes | All |
T34 | 1714-1721 | GeneOrGeneProduct | denotes | lesions |
T35 | 1755-1759 | GeneOrGeneProduct | denotes | pons |
T36 | 1821-1825 | GeneOrGeneProduct | denotes | in 5 |
T37 | 1840-1844 | GeneOrGeneProduct | denotes | in 1 |
T38 | 1856-1860 | GeneOrGeneProduct | denotes | them |
T39 | 1878-1884 | GeneOrGeneProduct | denotes | lesion |
T40 | 1885-1894 | GeneOrGeneProduct | denotes | persisted |
T41 | 1940-1947 | GeneOrGeneProduct | denotes | lesions |
T42 | 2008-2015 | GeneOrGeneProduct | denotes | induced |
T43 | 2052-2059 | GeneOrGeneProduct | denotes | nucleus |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 139-149 | GeneOrGeneProduct | denotes | attenuated |
T2 | 239-246 | GeneOrGeneProduct | denotes | lesions |
T3 | 347-357 | GeneOrGeneProduct | denotes | attenuated |
T4 | 715-720 | GeneOrGeneProduct | denotes | brain |
T5 | 1287-1291 | GeneOrGeneProduct | denotes | high |
T6 | 1366-1373 | GeneOrGeneProduct | denotes | nucleus |
T7 | 1481-1486 | GeneOrGeneProduct | denotes | white |
T8 | 1523-1530 | GeneOrGeneProduct | denotes | lesions |
T9 | 1612-1616 | GeneOrGeneProduct | denotes | high |
T10 | 1714-1721 | GeneOrGeneProduct | denotes | lesions |
T11 | 1940-1947 | GeneOrGeneProduct | denotes | lesions |
T12 | 2052-2059 | GeneOrGeneProduct | denotes | nucleus |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 63-77 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T2 | 272-286 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T3 | 533-547 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T4 | 678-687 | DiseaseOrPhenotypicFeature | denotes | infection | D007239 |
T5 | 2016-2030 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 1481-1486 | GeneOrGeneProduct | denotes | white |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 150-159 | DiseaseOrPhenotypicFeature | denotes | inversion | 0043678 |
T2 | 358-367 | DiseaseOrPhenotypicFeature | denotes | inversion | 0043678 |
T3 | 469-472 | DiseaseOrPhenotypicFeature | denotes | men | 0017169 |
T4 | 678-687 | DiseaseOrPhenotypicFeature | denotes | infection | 0005550 |
T5 | 848-851 | DiseaseOrPhenotypicFeature | denotes | ADC | 0020689 |
T6 | 1577-1580 | DiseaseOrPhenotypicFeature | denotes | ADC | 0020689 |
T7 | 1697-1700 | DiseaseOrPhenotypicFeature | denotes | ADC | 0020689 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 11-37 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesion | DISEASE |
T2 | 63-77 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T3 | 219-246 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE |
T4 | 272-286 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T5 | 533-547 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T6 | 678-687 | DiseaseOrPhenotypicFeature | denotes | infection | D007239 |
T7 | 1869-1884 | DiseaseOrPhenotypicFeature | denotes | callosal lesion | DISEASE |
T8 | 1920-1947 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE |
T9 | 2016-2030 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 11-37 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesion | DISEASE |
T2 | 63-77 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T3 | 219-246 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE |
T4 | 272-286 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T5 | 533-547 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
T6 | 1869-1884 | DiseaseOrPhenotypicFeature | denotes | callosal lesion | DISEASE |
T7 | 1920-1947 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE |
T8 | 2016-2030 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 41-54 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
T3 | 250-263 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
T5 | 511-524 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
T7 | 595-608 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
T9 | 848-851 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_35181|http://purl.obolibrary.org/obo/CHEBI_18198 |
T11 | 999-1012 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
T13 | 1577-1580 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_35181|http://purl.obolibrary.org/obo/CHEBI_18198 |
T15 | 1697-1700 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_35181|http://purl.obolibrary.org/obo/CHEBI_18198 |
T17 | 1994-2007 | ChemicalEntity | denotes | metronidazole | D008795|http://purl.obolibrary.org/obo/CHEBI_6909 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 457-465 | OrganismTaxon | denotes | patients |
T2 | 469-472 | OrganismTaxon | denotes | men |
T3 | 479-484 | OrganismTaxon | denotes | women |
T4 | 941-949 | OrganismTaxon | denotes | patients |
T5 | 1603-1610 | OrganismTaxon | denotes | patient |
T6 | 1826-1834 | OrganismTaxon | denotes | patients |
T7 | 1845-1852 | OrganismTaxon | denotes | patient |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T17 | 1994-2007 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T15 | 1697-1700 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_18198|http://purl.obolibrary.org/obo/CHEBI_35181 | |
T13 | 1577-1580 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_18198|http://purl.obolibrary.org/obo/CHEBI_35181 | |
T11 | 999-1012 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T9 | 848-851 | ChemicalEntity | denotes | ADC | http://purl.obolibrary.org/obo/CHEBI_18198|http://purl.obolibrary.org/obo/CHEBI_35181 | |
T7 | 595-608 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T5 | 511-524 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T3 | 250-263 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T1 | 41-54 | ChemicalEntity | denotes | metronidazole | http://purl.obolibrary.org/obo/CHEBI_6909|D008795 | |
T1171 | 1481-1486 | GeneOrGeneProduct | denotes | white | ||
T8 | 2016-2030 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 | |
T87488 | 1920-1947 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE | |
T6 | 1869-1884 | DiseaseOrPhenotypicFeature | denotes | callosal lesion | DISEASE | |
T3250 | 533-547 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 | |
T4 | 272-286 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 | |
T48117 | 219-246 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesions | DISEASE | |
T2 | 63-77 | DiseaseOrPhenotypicFeature | denotes | encephalopathy | D001927 | |
T62847 | 11-37 | DiseaseOrPhenotypicFeature | denotes | inferior colliculus lesion | DISEASE | |
T34289 | 1845-1852 | OrganismTaxon | denotes | patient | ||
T24628 | 1826-1834 | OrganismTaxon | denotes | patients | ||
T79130 | 1603-1610 | OrganismTaxon | denotes | patient | ||
T36043 | 941-949 | OrganismTaxon | denotes | patients | ||
T63029 | 479-484 | OrganismTaxon | denotes | women | ||
T18297 | 469-472 | OrganismTaxon | denotes | men | ||
T4605 | 457-465 | OrganismTaxon | denotes | patients |