| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-109 |
Sentence |
denotes |
Synthesis and carbohydrate-binding activity of poly(ethyleneglycol)-Ricinus communis agglutinin I conjugates. |
| TextSentencer_T2 |
110-261 |
Sentence |
denotes |
The synthesis of poly(ethyleneglycol) (PEG)-lectin conjugates was investigated to provide new reagents for evaluation as biological response modifiers. |
| TextSentencer_T3 |
262-379 |
Sentence |
denotes |
PEG was activated with 1,1'-carbonyldiimidazole (CDI), followed by conjugation with Ricinus communis I (RCAI) lectin. |
| TextSentencer_T4 |
380-458 |
Sentence |
denotes |
The resulting conjugates were heterodisperse with respect to molecular weight. |
| TextSentencer_T5 |
459-502 |
Sentence |
denotes |
Carbohydrate-binding activity was retained. |
| TextSentencer_T6 |
503-627 |
Sentence |
denotes |
The conjugates were separated by affinity chromatography into fractions differing in apparent carbohydrate-binding affinity. |
| TextSentencer_T7 |
628-667 |
Sentence |
denotes |
Conjugation of RCAI with PEG 4 (mol.wt. |
| TextSentencer_T8 |
668-691 |
Sentence |
denotes |
3350) or PEG 6 (mol.wt. |
| TextSentencer_T9 |
692-812 |
Sentence |
denotes |
8000) appeared to provide less hindrance of the lectin binding site compared to conjugates prepared with PEG 20 (mol.wt. |
| TextSentencer_T10 |
813-821 |
Sentence |
denotes |
20,000). |
| TextSentencer_T11 |
822-993 |
Sentence |
denotes |
Results of free amine assays indicated that higher ratios of PEG to RCAI in conjugates correlated with loss of low-affinity binding and retention of high-affinity binding. |
| TextSentencer_T12 |
994-1077 |
Sentence |
denotes |
The data showed the feasibility of preparing PEG-lectin conjugates for in vivo use. |
| T1 |
0-109 |
Sentence |
denotes |
Synthesis and carbohydrate-binding activity of poly(ethyleneglycol)-Ricinus communis agglutinin I conjugates. |
| T2 |
110-261 |
Sentence |
denotes |
The synthesis of poly(ethyleneglycol) (PEG)-lectin conjugates was investigated to provide new reagents for evaluation as biological response modifiers. |
| T3 |
262-379 |
Sentence |
denotes |
PEG was activated with 1,1'-carbonyldiimidazole (CDI), followed by conjugation with Ricinus communis I (RCAI) lectin. |
| T4 |
380-458 |
Sentence |
denotes |
The resulting conjugates were heterodisperse with respect to molecular weight. |
| T5 |
459-502 |
Sentence |
denotes |
Carbohydrate-binding activity was retained. |
| T6 |
503-627 |
Sentence |
denotes |
The conjugates were separated by affinity chromatography into fractions differing in apparent carbohydrate-binding affinity. |
| T7 |
628-667 |
Sentence |
denotes |
Conjugation of RCAI with PEG 4 (mol.wt. |
| T8 |
668-691 |
Sentence |
denotes |
3350) or PEG 6 (mol.wt. |
| T9 |
692-812 |
Sentence |
denotes |
8000) appeared to provide less hindrance of the lectin binding site compared to conjugates prepared with PEG 20 (mol.wt. |
| T10 |
813-821 |
Sentence |
denotes |
20,000). |
| T11 |
822-993 |
Sentence |
denotes |
Results of free amine assays indicated that higher ratios of PEG to RCAI in conjugates correlated with loss of low-affinity binding and retention of high-affinity binding. |
| T12 |
994-1077 |
Sentence |
denotes |
The data showed the feasibility of preparing PEG-lectin conjugates for in vivo use. |