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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 47-62 DNA denotes HTLV-I enhancer
T2 88-103 protein denotes trans-activator
T3 159-176 DNA denotes enhancer elements
T4 234-252 cell_line denotes human T-cell lines
T5 253-259 cell_line denotes Jurkat
T6 264-270 cell_line denotes MOLT 4
T7 429-444 DNA denotes HTLV-I enhancer
T8 457-487 DNA denotes 21-base-pair (bp) core element
T9 543-558 protein denotes trans-activator
T10 559-565 protein denotes p40tax
T11 602-665 protein denotes cyclic-AMP responsive element binding factor (CREB)-like factor
T12 715-729 DNA denotes 21-bp elements
T13 811-825 DNA denotes 21-bp elements
T14 861-867 protein denotes p40tax
T15 900-930 protein denotes NF-kappa B-like nuclear factor
T16 960-979 protein denotes protein-DNA complex
T17 989-1004 protein denotes C26 subfragment
T18 1032-1038 protein denotes p40tax
T19 1044-1055 DNA denotes C26 element
T20 1092-1098 protein denotes p40tax
T21 1130-1143 DNA denotes 21-bp element
T22 1201-1207 protein denotes p40tax
T23 1222-1233 DNA denotes C26 element
T24 1287-1293 protein denotes p40tax
T25 1308-1335 DNA denotes NF-kappa B-binding elements
T26 1354-1365 DNA denotes C26 element
T27 1500-1515 DNA denotes HTLV-I enhancer
T28 1525-1553 DNA denotes multiple functional elements
T29 1592-1625 protein denotes CREB- and NF-kappa B-like factors
T30 1680-1695 DNA denotes HTLV-I enhancer
T31 1711-1717 protein denotes p40tax
T32 1785-1800 DNA denotes HTLV-I enhancer
T33 1829-1840 DNA denotes C26 element

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-114 Sentence denotes Synergism between two distinct elements of the HTLV-I enhancer during activation by the trans-activator of HTLV-I.
S2 115-366 Sentence denotes We have conducted functional studies of the enhancer elements of human T-cell leukemia virus type I (HTLV-I) using the human T-cell lines Jurkat and MOLT 4, which are negative for HTLV-I, and MT-2 and TL-Mor, which carry the proviral genome of HTLV-I.
S3 367-445 Sentence denotes Two distinct elements have been implicated in function of the HTLV-I enhancer.
S4 446-669 Sentence denotes One is the 21-base-pair (bp) core element that is responsible for trans-activation by the HTLV-I trans-activator p40tax and that has the ability to bind to cyclic-AMP responsive element binding factor (CREB)-like factor(s).
S5 670-730 Sentence denotes The other is a region interposed between the 21-bp elements.
S6 731-942 Sentence denotes In this study we demonstrate that a subfragment (C26) in the region between the 21-bp elements is involved in trans-activation by p40tax, possibly through binding to an NF-kappa B-like nuclear factor or factors.
S7 943-1039 Sentence denotes Formation of the protein-DNA complex with the C26 subfragment was positively affected by p40tax.
S8 1040-1208 Sentence denotes The C26 element conferred partial responsiveness to p40tax when linked to one copy of the 21-bp element that, by itself, showed little activation in response to p40tax.
S9 1209-1336 Sentence denotes However, the C26 element alone, even when repeated, could not be activated by p40tax, unlike other NF-kappa B-binding elements.
S10 1337-1457 Sentence denotes In contrast, the C26 element itself was profoundly activated upon stimulation with 12-O-tetradecanoylphorbol-13-acetate.
S11 1458-1718 Sentence denotes These findings therefore suggest that the HTLV-I enhancer contains multiple functional elements, including binding sites for at least CREB- and NF-kappa B-like factors, which synergistically cooperate in activation of the HTLV-I enhancer in response to p40tax.
S12 1719-1841 Sentence denotes Our results also demonstrate that TPA-dependent activation of the HTLV-I enhancer may be mediated through the C26 element.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 47-53 NP denotes HTLV-I
C1 43-62 NP denotes the HTLV-I enhancer
C3 107-113 NP denotes HTLV-I
C5 180-223 NP denotes human T-cell leukemia virus type I (HTLV-I)
C4 155-223 NP denotes the enhancer elements of human T-cell leukemia virus type I (HTLV-I)
C6 230-270 NP denotes the human T-cell lines Jurkat and MOLT 4
C7 272-277 NP denotes which
C8 295-301 NP denotes HTLV-I
C9 307-322 NP denotes MT-2 and TL-Mor
C10 324-329 NP denotes which
C11 359-365 NP denotes HTLV-I
C12 367-388 NP denotes Two distinct elements
C14 429-435 NP denotes HTLV-I
C13 425-444 NP denotes the HTLV-I enhancer
C15 453-487 NP denotes the 21-base-pair (bp) core element
C16 488-492 NP denotes that
C17 532-565 NP denotes the HTLV-I trans-activator p40tax
C18 570-574 NP denotes that
C19 602-668 NP denotes cyclic-AMP responsive element binding factor (CREB)-like factor(s)
C20 670-679 NP denotes The other
C22 711-729 NP denotes the 21-bp elements
C21 683-729 NP denotes a region interposed between the 21-bp elements
C23 765-784 NP denotes a subfragment (C26)
C25 807-825 NP denotes the 21-bp elements
C24 788-825 NP denotes the region between the 21-bp elements
C26 861-867 NP denotes p40tax
C27 897-930 NP denotes an NF-kappa B-like nuclear factor
C28 985-1004 NP denotes the C26 subfragment
C29 1032-1038 NP denotes p40tax
C30 1040-1055 NP denotes The C26 element
C31 1092-1098 NP denotes p40tax
C32 1126-1143 NP denotes the 21-bp element
C33 1144-1148 NP denotes that
C34 1153-1159 NP denotes itself
C35 1201-1207 NP denotes p40tax
C36 1218-1233 NP denotes the C26 element
C37 1287-1293 NP denotes p40tax
C38 1350-1365 NP denotes the C26 element
C39 1366-1372 NP denotes itself
C41 1500-1506 NP denotes HTLV-I
C40 1496-1515 NP denotes the HTLV-I enhancer
C43 1592-1596 NP denotes CREB
C44 1602-1625 NP denotes NF-kappa B-like factors
C42 1565-1625 NP denotes binding sites for at least CREB- and NF-kappa B-like factors
C45 1627-1632 NP denotes which
C47 1680-1686 NP denotes HTLV-I
C46 1676-1695 NP denotes the HTLV-I enhancer
C48 1711-1717 NP denotes p40tax
C50 1785-1791 NP denotes HTLV-I
C49 1781-1800 NP denotes the HTLV-I enhancer
C51 1825-1840 NP denotes the C26 element
R1 C3 C2 coref-ident HTLV-I,HTLV-I
R2 C5 C3 coref-ident human T-cell leukemia virus type I (HTLV-I),HTLV-I
R3 C4 C1 coref-ident the enhancer elements of human T-cell leukemia virus type I (HTLV-I),the HTLV-I enhancer
R4 C7 C6 coref-relat which,the human T-cell lines Jurkat and MOLT 4
R5 C8 C5 coref-ident HTLV-I,human T-cell leukemia virus type I (HTLV-I)
R6 C10 C9 coref-relat which,MT-2 and TL-Mor
R7 C11 C8 coref-ident HTLV-I,HTLV-I
R8 C14 C11 coref-ident HTLV-I,HTLV-I
R9 C13 C4 coref-ident the HTLV-I enhancer,the enhancer elements of human T-cell leukemia virus type I (HTLV-I)
R10 C15 C12 coref-other the 21-base-pair (bp) core element,Two distinct elements
R11 C16 C15 coref-relat that,the 21-base-pair (bp) core element
R12 C18 C15 coref-relat that,the 21-base-pair (bp) core element
R13 C20 C12 coref-other The other,Two distinct elements
R14 C25 C22 coref-ident the 21-bp elements,the 21-bp elements
R15 C24 C21 coref-ident the region between the 21-bp elements,a region interposed between the 21-bp elements
R16 C26 C17 coref-ident p40tax,the HTLV-I trans-activator p40tax
R17 C28 C23 coref-ident the C26 subfragment,a subfragment (C26)
R18 C29 C26 coref-ident p40tax,p40tax
R19 C30 C28 coref-ident The C26 element,the C26 subfragment
R20 C31 C29 coref-ident p40tax,p40tax
R21 C32 C25 coref-ident the 21-bp element,the 21-bp elements
R22 C33 C32 coref-relat that,the 21-bp element
R23 C34 C32 coref-pron itself,the 21-bp element
R24 C35 C31 coref-ident p40tax,p40tax
R25 C36 C30 coref-ident the C26 element,The C26 element
R26 C37 C35 coref-ident p40tax,p40tax
R27 C38 C36 coref-ident the C26 element,the C26 element
R28 C39 C38 coref-pron itself,the C26 element
R29 C41 C14 coref-ident HTLV-I,HTLV-I
R30 C40 C13 coref-ident the HTLV-I enhancer,the HTLV-I enhancer
R31 C43 C19 coref-ident CREB,cyclic-AMP responsive element binding factor (CREB)-like factor(s)
R32 C44 C27 coref-ident NF-kappa B-like factors,an NF-kappa B-like nuclear factor
R33 C45 C42 coref-relat which,binding sites for at least CREB- and NF-kappa B-like factors
R34 C47 C41 coref-ident HTLV-I,HTLV-I
R35 C46 C40 coref-ident the HTLV-I enhancer,the HTLV-I enhancer
R36 C48 C37 coref-ident p40tax,p40tax
R37 C50 C47 coref-ident HTLV-I,HTLV-I
R38 C49 C46 coref-ident the HTLV-I enhancer,the HTLV-I enhancer
R39 C51 C38 coref-ident the C26 element,the C26 element

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 47-62 DNA_domain_or_region denotes HTLV-I enhancer
T2 88-103 protein_family_or_group denotes trans-activator
T3 107-113 virus denotes HTLV-I
T4 159-176 DNA_domain_or_region denotes enhancer elements
T5 180-214 virus denotes human T-cell leukemia virus type I
T6 216-222 virus denotes HTLV-I
T7 234-252 cell_line denotes human T-cell lines
T8 253-259 cell_line denotes Jurkat
T9 264-270 cell_line denotes MOLT 4
T10 295-301 virus denotes HTLV-I
T11 307-311 virus denotes MT-2
T12 316-322 virus denotes TL-Mor
T13 359-365 virus denotes HTLV-I
T14 429-435 virus denotes HTLV-I
T15 457-487 DNA_domain_or_region denotes 21-base-pair (bp) core element
T16 512-528 other_name denotes trans-activation
T17 536-542 virus denotes HTLV-I
T18 543-558 protein_family_or_group denotes trans-activator
T19 559-565 protein_molecule denotes p40tax
T20 602-646 protein_molecule denotes cyclic-AMP responsive element binding factor
T21 648-652 protein_molecule denotes CREB
T22 715-729 DNA_domain_or_region denotes 21-bp elements
T23 811-825 DNA_domain_or_region denotes 21-bp elements
T24 841-857 other_name denotes trans-activation
T25 861-867 protein_molecule denotes p40tax
T26 900-910 protein_molecule denotes NF-kappa B
T27 960-979 protein_complex denotes protein-DNA complex
T28 989-1004 protein_subunit denotes C26 subfragment
T29 1032-1038 protein_molecule denotes p40tax
T30 1044-1055 DNA_domain_or_region denotes C26 element
T31 1092-1098 protein_molecule denotes p40tax
T32 1130-1143 DNA_domain_or_region denotes 21-bp element
T33 1201-1207 protein_molecule denotes p40tax
T34 1222-1233 DNA_domain_or_region denotes C26 element
T35 1287-1293 protein_molecule denotes p40tax
T36 1308-1318 protein_molecule denotes NF-kappa B
T37 1354-1365 DNA_domain_or_region denotes C26 element
T38 1420-1456 other_organic_compound denotes 12-O-tetradecanoylphorbol-13-acetate
T39 1500-1506 virus denotes HTLV-I
T40 1525-1553 DNA_domain_or_region denotes multiple functional elements
T41 1680-1686 virus denotes HTLV-I
T42 1711-1717 protein_molecule denotes p40tax
T43 1753-1777 other_name denotes TPA-dependent activation
T44 1785-1791 virus denotes HTLV-I
T45 1829-1840 DNA_domain_or_region denotes C26 element