PubMed:19306381 / 1637-1877 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":240},"obj":"Sentence"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}

{"project":"LitCoin-entities","denotations":[{"id":"5899","span":{"begin":6,"end":16},"obj":"GeneOrGeneProduct"},{"id":"5900","span":{"begin":53,"end":60},"obj":"GeneOrGeneProduct"},{"id":"5901","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"5902","span":{"begin":67,"end":70},"obj":"GeneOrGeneProduct"},{"id":"5903","span":{"begin":72,"end":75},"obj":"GeneOrGeneProduct"},{"id":"5904","span":{"begin":80,"end":98},"obj":"GeneOrGeneProduct"},{"id":"5905","span":{"begin":100,"end":111},"obj":"GeneOrGeneProduct"},{"id":"5906","span":{"begin":129,"end":132},"obj":"GeneOrGeneProduct"},{"id":"5907","span":{"begin":212,"end":222},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A59","pred":"db_id","subj":"5899","obj":"NCBIGene:3084"},{"id":"A60","pred":"db_id","subj":"5900","obj":"NCBIGene:26413"},{"id":"A61","pred":"db_id","subj":"5900","obj":"NCBIGene:26417"},{"id":"A62","pred":"db_id","subj":"5900","obj":"NCBIGene:5594"},{"id":"A63","pred":"db_id","subj":"5900","obj":"NCBIGene:5595"},{"id":"A64","pred":"db_id","subj":"5901","obj":"NCBIGene:26419"},{"id":"A65","pred":"db_id","subj":"5901","obj":"NCBIGene:5599"},{"id":"A66","pred":"db_id","subj":"5902","obj":"NCBIGene:26419"},{"id":"A67","pred":"db_id","subj":"5902","obj":"NCBIGene:5599"},{"id":"A68","pred":"db_id","subj":"5903","obj":"NCBIGene:11651"},{"id":"A69","pred":"db_id","subj":"5903","obj":"NCBIGene:207"},{"id":"A70","pred":"db_id","subj":"5904","obj":"NCBIGene:20779"},{"id":"A71","pred":"db_id","subj":"5904","obj":"NCBIGene:6714"},{"id":"A72","pred":"db_id","subj":"5905","obj":"NCBIGene:3084"},{"id":"A73","pred":"db_id","subj":"5906","obj":"NCBIGene:11651"},{"id":"A74","pred":"db_id","subj":"5906","obj":"NCBIGene:207"},{"id":"A75","pred":"db_id","subj":"5907","obj":"NCBIGene:3084"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T68","span":{"begin":6,"end":11},"obj":"GeneOrGeneProduct"},{"id":"T69","span":{"begin":12,"end":16},"obj":"GeneOrGeneProduct"},{"id":"T70","span":{"begin":30,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T71","span":{"begin":43,"end":52},"obj":"GeneOrGeneProduct"},{"id":"T72","span":{"begin":53,"end":60},"obj":"GeneOrGeneProduct"},{"id":"T73","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T74","span":{"begin":80,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T75","span":{"begin":100,"end":105},"obj":"GeneOrGeneProduct"},{"id":"T76","span":{"begin":106,"end":111},"obj":"GeneOrGeneProduct"},{"id":"T77","span":{"begin":120,"end":128},"obj":"GeneOrGeneProduct"},{"id":"T78","span":{"begin":137,"end":146},"obj":"GeneOrGeneProduct"},{"id":"T79","span":{"begin":153,"end":158},"obj":"GeneOrGeneProduct"},{"id":"T80","span":{"begin":159,"end":166},"obj":"GeneOrGeneProduct"},{"id":"T81","span":{"begin":212,"end":217},"obj":"GeneOrGeneProduct"},{"id":"T82","span":{"begin":218,"end":222},"obj":"GeneOrGeneProduct"},{"id":"T83","span":{"begin":234,"end":239},"obj":"GeneOrGeneProduct"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T52","span":{"begin":6,"end":11},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":12,"end":16},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":53,"end":60},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":80,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":100,"end":105},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":106,"end":111},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":153,"end":158},"obj":"GeneOrGeneProduct"},{"id":"T60","span":{"begin":212,"end":217},"obj":"GeneOrGeneProduct"},{"id":"T61","span":{"begin":218,"end":222},"obj":"GeneOrGeneProduct"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T35","span":{"begin":6,"end":11},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":53,"end":60},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":72,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":80,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":100,"end":105},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":106,"end":111},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":129,"end":132},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":212,"end":217},"obj":"GeneOrGeneProduct"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T43","span":{"begin":212,"end":217},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":129,"end":132},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":106,"end":111},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":100,"end":105},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":80,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":72,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":62,"end":66},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":53,"end":60},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":6,"end":11},"obj":"GeneOrGeneProduct"}],"text":"While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells."}