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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.
T2 140-268 Sentence denotes Malignant peripheral nerve sheath tumors (MPNSTs) are the most common malignancy associated with neurofibromatosis Type 1 (NF1).
T3 269-406 Sentence denotes These Schwann cell lineage-derived sarcomas aggressively invade adjacent nerve and soft tissue, frequently precluding surgical resection.
T4 407-482 Sentence denotes Little is known regarding the mechanisms underlying this invasive behavior.
T5 483-689 Sentence denotes We have shown that MPNSTs express neuregulin-1 (NRG-1) beta isoforms, which promote Schwann cell migration during development, and NRG-1 alpha isoforms, whose effects on Schwann cells are poorly understood.
T6 690-927 Sentence denotes Hypothesizing that NRG-1 beta and/or NRG-1 alpha promote MPNST invasion, we found that NRG-1 beta promoted MPNST migration in a substrate-specific manner, markedly enhancing migration on laminin but not on collagen type I or fibronectin.
T7 928-1168 Sentence denotes The NRG-1 receptors erbB3 and erbB4 were present in MPNST invadopodia (processes mediating invasion), partially colocalized with focal adhesion kinase and the laminin receptor beta(1)-integrin and coimmunoprecipitated with beta(1)-integrin.
T8 1169-1348 Sentence denotes NRG-1 beta stimulated human and murine MPNST cell migration and invasion in a concentration-dependent manner in three-dimensional migration assays, acting as a chemotactic factor.
T9 1349-1508 Sentence denotes Both baseline and NRG-1 beta-induced migration were erbB-dependent and required the action of MEK 1/2, SAPK/JNK, PI-3 kinase, Src family kinases and ROCK-I/II.
T10 1509-1636 Sentence denotes In contrast, NRG-1 alpha had no effect on the migration and invasion of some MPNST lines and inhibited the migration of others.
T11 1637-1877 Sentence denotes While NRG-1 beta potently and persistently activated Erk 1/2, SAPK/JNK, Akt and Src family kinases, NRG-1 alpha did not activate Akt and activated these other kinases with kinetics distinct from those evident in NRG-1 beta-stimulated cells.
T12 1878-2015 Sentence denotes These findings suggest that NRG-1 beta enhances MPNST migration and that NRG-1 beta and NRG-1 alpha differentially modulate this process.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 1191-1196 OrganismTaxon denotes human NCBItxid:9606

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
5857 0-17 GeneOrGeneProduct denotes Neuregulin-1 beta NCBIGene:3084
5858 22-40 GeneOrGeneProduct denotes neuregulin-1 alpha NCBIGene:3084
5859 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor MESH:D018319
5860 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors MESH:D018319
5861 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs MESH:D018319
5862 210-220 DiseaseOrPhenotypicFeature denotes malignancy MESH:D009369
5863 237-261 GeneOrGeneProduct denotes neurofibromatosis Type 1 NCBIGene:4763
5864 263-266 GeneOrGeneProduct denotes NF1 NCBIGene:4763
5865 304-312 DiseaseOrPhenotypicFeature denotes sarcomas MESH:D012509
5866 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs MESH:D018319
5867 517-542 GeneOrGeneProduct denotes neuregulin-1 (NRG-1) beta NCBIGene:3084
5868 614-625 GeneOrGeneProduct denotes NRG-1 alpha NCBIGene:3084
5869 709-719 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5870 727-738 GeneOrGeneProduct denotes NRG-1 alpha NCBIGene:3084
5871 747-752 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5872 777-787 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5873 797-802 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5874 877-884 GeneOrGeneProduct denotes laminin NCBIGene:16777
5875 896-911 GeneOrGeneProduct denotes collagen type I NCBIGene:1277|NCBIGene:1278
5876 915-926 GeneOrGeneProduct denotes fibronectin NCBIGene:2335
5877 932-937 GeneOrGeneProduct denotes NRG-1 NCBIGene:3084
5878 948-953 GeneOrGeneProduct denotes erbB3 NCBIGene:13867|NCBIGene:2065
5879 958-963 GeneOrGeneProduct denotes erbB4 NCBIGene:13869|NCBIGene:2066
5880 980-985 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5881 1057-1078 GeneOrGeneProduct denotes focal adhesion kinase NCBIGene:5747
5882 1087-1103 GeneOrGeneProduct denotes laminin receptor NCBIGene:3688
5883 1104-1120 GeneOrGeneProduct denotes beta(1)-integrin NCBIGene:3688
5884 1151-1167 GeneOrGeneProduct denotes beta(1)-integrin NCBIGene:3688
5885 1169-1179 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5886 1191-1196 OrganismTaxon denotes human NCBITaxon:9606
5887 1201-1207 OrganismTaxon denotes murine NCBITaxon:10090
5888 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5889 1367-1377 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5890 1401-1405 GeneOrGeneProduct denotes erbB NCBIGene:13867|NCBIGene:13869|NCBIGene:2065|NCBIGene:2066
5891 1443-1450 GeneOrGeneProduct denotes MEK 1/2 NCBIGene:26395|NCBIGene:26396|NCBIGene:5604|NCBIGene:5605
5892 1452-1456 GeneOrGeneProduct denotes SAPK NCBIGene:26419|NCBIGene:5599
5893 1457-1460 GeneOrGeneProduct denotes JNK NCBIGene:26419|NCBIGene:5599
5894 1462-1473 GeneOrGeneProduct denotes PI-3 kinase NCBIGene:30955|NCBIGene:5290
5895 1475-1493 GeneOrGeneProduct denotes Src family kinases NCBIGene:20779|NCBIGene:6714
5896 1498-1507 GeneOrGeneProduct denotes ROCK-I/II NCBIGene:19877|NCBIGene:19878|NCBIGene:6093|NCBIGene:9475
5897 1522-1533 GeneOrGeneProduct denotes NRG-1 alpha NCBIGene:3084
5898 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5899 1643-1653 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5900 1690-1697 GeneOrGeneProduct denotes Erk 1/2 NCBIGene:26413|NCBIGene:26417|NCBIGene:5594|NCBIGene:5595
5901 1699-1703 GeneOrGeneProduct denotes SAPK NCBIGene:26419|NCBIGene:5599
5902 1704-1707 GeneOrGeneProduct denotes JNK NCBIGene:26419|NCBIGene:5599
5903 1709-1712 GeneOrGeneProduct denotes Akt NCBIGene:11651|NCBIGene:207
5904 1717-1735 GeneOrGeneProduct denotes Src family kinases NCBIGene:20779|NCBIGene:6714
5905 1737-1748 GeneOrGeneProduct denotes NRG-1 alpha NCBIGene:3084
5906 1766-1769 GeneOrGeneProduct denotes Akt NCBIGene:11651|NCBIGene:207
5907 1849-1859 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5908 1906-1916 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5909 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST MESH:D018319
5910 1951-1961 GeneOrGeneProduct denotes NRG-1 beta NCBIGene:3084
5911 1966-1977 GeneOrGeneProduct denotes NRG-1 alpha NCBIGene:3084

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor 0017827
T2 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors 0017827
T3 237-261 DiseaseOrPhenotypicFeature denotes neurofibromatosis Type 1 0018975
T4 237-254 DiseaseOrPhenotypicFeature denotes neurofibromatosis 0021061
T5 304-312 DiseaseOrPhenotypicFeature denotes sarcomas 0005089

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Neuregulin
T2 13-17 GeneOrGeneProduct denotes beta
T3 22-32 GeneOrGeneProduct denotes neuregulin
T4 35-40 GeneOrGeneProduct denotes alpha
T5 120-126 GeneOrGeneProduct denotes sheath
T6 127-132 GeneOrGeneProduct denotes tumor
T7 133-138 GeneOrGeneProduct denotes cells
T8 167-173 GeneOrGeneProduct denotes sheath
T9 174-180 GeneOrGeneProduct denotes tumors
T10 237-261 GeneOrGeneProduct denotes neurofibromatosis Type 1
T11 263-266 GeneOrGeneProduct denotes NF1
T12 283-287 GeneOrGeneProduct denotes cell
T13 352-356 GeneOrGeneProduct denotes soft
T14 407-413 GeneOrGeneProduct denotes Little
T15 473-481 GeneOrGeneProduct denotes behavior
T16 517-527 GeneOrGeneProduct denotes neuregulin
T17 531-536 GeneOrGeneProduct denotes NRG-1
T18 538-542 GeneOrGeneProduct denotes beta
T19 575-579 GeneOrGeneProduct denotes cell
T20 614-619 GeneOrGeneProduct denotes NRG-1
T21 620-625 GeneOrGeneProduct denotes alpha
T22 661-666 GeneOrGeneProduct denotes cells
T23 709-714 GeneOrGeneProduct denotes NRG-1
T24 715-719 GeneOrGeneProduct denotes beta
T25 727-732 GeneOrGeneProduct denotes NRG-1
T26 733-738 GeneOrGeneProduct denotes alpha
T27 777-782 GeneOrGeneProduct denotes NRG-1
T28 783-787 GeneOrGeneProduct denotes beta
T29 813-817 GeneOrGeneProduct denotes in a
T30 845-853 GeneOrGeneProduct denotes markedly
T31 877-884 GeneOrGeneProduct denotes laminin
T32 896-904 GeneOrGeneProduct denotes collagen
T33 905-911 GeneOrGeneProduct denotes type I
T34 915-926 GeneOrGeneProduct denotes fibronectin
T35 932-937 GeneOrGeneProduct denotes NRG-1
T36 938-947 GeneOrGeneProduct denotes receptors
T37 948-953 GeneOrGeneProduct denotes erbB3
T38 958-963 GeneOrGeneProduct denotes erbB4
T39 999-1008 GeneOrGeneProduct denotes processes
T40 1009-1018 GeneOrGeneProduct denotes mediating
T41 1057-1078 GeneOrGeneProduct denotes focal adhesion kinase
T42 1087-1103 GeneOrGeneProduct denotes laminin receptor
T43 1104-1108 GeneOrGeneProduct denotes beta
T44 1112-1120 GeneOrGeneProduct denotes integrin
T45 1151-1155 GeneOrGeneProduct denotes beta
T46 1159-1167 GeneOrGeneProduct denotes integrin
T47 1169-1174 GeneOrGeneProduct denotes NRG-1
T48 1175-1179 GeneOrGeneProduct denotes beta
T49 1214-1218 GeneOrGeneProduct denotes cell
T50 1242-1246 GeneOrGeneProduct denotes in a
T51 1317-1328 GeneOrGeneProduct denotes acting as a
T52 1341-1347 GeneOrGeneProduct denotes factor
T53 1367-1372 GeneOrGeneProduct denotes NRG-1
T54 1373-1377 GeneOrGeneProduct denotes beta
T55 1378-1385 GeneOrGeneProduct denotes induced
T56 1401-1405 GeneOrGeneProduct denotes erbB
T57 1443-1448 GeneOrGeneProduct denotes MEK 1
T58 1452-1456 GeneOrGeneProduct denotes SAPK
T59 1462-1473 GeneOrGeneProduct denotes PI-3 kinase
T60 1475-1493 GeneOrGeneProduct denotes Src family kinases
T61 1498-1504 GeneOrGeneProduct denotes ROCK-I
T62 1505-1507 GeneOrGeneProduct denotes II
T63 1512-1520 GeneOrGeneProduct denotes contrast
T64 1522-1527 GeneOrGeneProduct denotes NRG-1
T65 1528-1533 GeneOrGeneProduct denotes alpha
T66 1592-1597 GeneOrGeneProduct denotes lines
T67 1629-1635 GeneOrGeneProduct denotes others
T68 1643-1648 GeneOrGeneProduct denotes NRG-1
T69 1649-1653 GeneOrGeneProduct denotes beta
T70 1667-1679 GeneOrGeneProduct denotes persistently
T71 1680-1689 GeneOrGeneProduct denotes activated
T72 1690-1697 GeneOrGeneProduct denotes Erk 1/2
T73 1699-1703 GeneOrGeneProduct denotes SAPK
T74 1717-1735 GeneOrGeneProduct denotes Src family kinases
T75 1737-1742 GeneOrGeneProduct denotes NRG-1
T76 1743-1748 GeneOrGeneProduct denotes alpha
T77 1757-1765 GeneOrGeneProduct denotes activate
T78 1774-1783 GeneOrGeneProduct denotes activated
T79 1790-1795 GeneOrGeneProduct denotes other
T80 1796-1803 GeneOrGeneProduct denotes kinases
T81 1849-1854 GeneOrGeneProduct denotes NRG-1
T82 1855-1859 GeneOrGeneProduct denotes beta
T83 1871-1876 GeneOrGeneProduct denotes cells
T84 1884-1892 GeneOrGeneProduct denotes findings
T85 1906-1911 GeneOrGeneProduct denotes NRG-1
T86 1912-1916 GeneOrGeneProduct denotes beta
T87 1951-1956 GeneOrGeneProduct denotes NRG-1
T88 1957-1961 GeneOrGeneProduct denotes beta
T89 1966-1971 GeneOrGeneProduct denotes NRG-1
T90 1972-1977 GeneOrGeneProduct denotes alpha
T91 2007-2014 GeneOrGeneProduct denotes process

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Neuregulin
T2 13-17 GeneOrGeneProduct denotes beta
T3 22-32 GeneOrGeneProduct denotes neuregulin
T4 35-40 GeneOrGeneProduct denotes alpha
T5 120-126 GeneOrGeneProduct denotes sheath
T6 167-173 GeneOrGeneProduct denotes sheath
T7 237-261 GeneOrGeneProduct denotes neurofibromatosis Type 1
T8 263-266 GeneOrGeneProduct denotes NF1
T9 283-287 GeneOrGeneProduct denotes cell
T10 352-356 GeneOrGeneProduct denotes soft
T11 407-413 GeneOrGeneProduct denotes Little
T12 473-481 GeneOrGeneProduct denotes behavior
T13 517-527 GeneOrGeneProduct denotes neuregulin
T14 531-536 GeneOrGeneProduct denotes NRG-1
T15 538-542 GeneOrGeneProduct denotes beta
T16 575-579 GeneOrGeneProduct denotes cell
T17 614-619 GeneOrGeneProduct denotes NRG-1
T18 620-625 GeneOrGeneProduct denotes alpha
T19 709-714 GeneOrGeneProduct denotes NRG-1
T20 715-719 GeneOrGeneProduct denotes beta
T21 727-732 GeneOrGeneProduct denotes NRG-1
T22 733-738 GeneOrGeneProduct denotes alpha
T23 777-782 GeneOrGeneProduct denotes NRG-1
T24 783-787 GeneOrGeneProduct denotes beta
T25 877-884 GeneOrGeneProduct denotes laminin
T26 896-904 GeneOrGeneProduct denotes collagen
T27 905-911 GeneOrGeneProduct denotes type I
T28 915-926 GeneOrGeneProduct denotes fibronectin
T29 932-937 GeneOrGeneProduct denotes NRG-1
T30 948-953 GeneOrGeneProduct denotes erbB3
T31 958-963 GeneOrGeneProduct denotes erbB4
T32 1057-1078 GeneOrGeneProduct denotes focal adhesion kinase
T33 1087-1103 GeneOrGeneProduct denotes laminin receptor
T34 1104-1108 GeneOrGeneProduct denotes beta
T35 1112-1120 GeneOrGeneProduct denotes integrin
T36 1151-1155 GeneOrGeneProduct denotes beta
T37 1159-1167 GeneOrGeneProduct denotes integrin
T38 1169-1174 GeneOrGeneProduct denotes NRG-1
T39 1175-1179 GeneOrGeneProduct denotes beta
T40 1214-1218 GeneOrGeneProduct denotes cell
T41 1341-1347 GeneOrGeneProduct denotes factor
T42 1367-1372 GeneOrGeneProduct denotes NRG-1
T43 1373-1377 GeneOrGeneProduct denotes beta
T44 1443-1448 GeneOrGeneProduct denotes MEK 1
T45 1452-1456 GeneOrGeneProduct denotes SAPK
T46 1462-1473 GeneOrGeneProduct denotes PI-3 kinase
T47 1475-1493 GeneOrGeneProduct denotes Src family kinases
T48 1498-1504 GeneOrGeneProduct denotes ROCK-I
T49 1522-1527 GeneOrGeneProduct denotes NRG-1
T50 1528-1533 GeneOrGeneProduct denotes alpha
T51 1592-1597 GeneOrGeneProduct denotes lines
T52 1643-1648 GeneOrGeneProduct denotes NRG-1
T53 1649-1653 GeneOrGeneProduct denotes beta
T54 1690-1697 GeneOrGeneProduct denotes Erk 1/2
T55 1699-1703 GeneOrGeneProduct denotes SAPK
T56 1717-1735 GeneOrGeneProduct denotes Src family kinases
T57 1737-1742 GeneOrGeneProduct denotes NRG-1
T58 1743-1748 GeneOrGeneProduct denotes alpha
T59 1790-1795 GeneOrGeneProduct denotes other
T60 1849-1854 GeneOrGeneProduct denotes NRG-1
T61 1855-1859 GeneOrGeneProduct denotes beta
T62 1906-1911 GeneOrGeneProduct denotes NRG-1
T63 1912-1916 GeneOrGeneProduct denotes beta
T64 1951-1956 GeneOrGeneProduct denotes NRG-1
T65 1957-1961 GeneOrGeneProduct denotes beta
T66 1966-1971 GeneOrGeneProduct denotes NRG-1
T67 1972-1977 GeneOrGeneProduct denotes alpha

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor D018319
T2 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors D018319
T3 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T4 210-220 DiseaseOrPhenotypicFeature denotes malignancy D009369
T5 237-261 DiseaseOrPhenotypicFeature denotes neurofibromatosis Type 1 D009456
T6 263-266 DiseaseOrPhenotypicFeature denotes NF1 D009456
T7 304-312 DiseaseOrPhenotypicFeature denotes sarcomas D012509
T8 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T9 747-752 DiseaseOrPhenotypicFeature denotes MPNST D018319
T10 797-802 DiseaseOrPhenotypicFeature denotes MPNST D018319
T11 980-985 DiseaseOrPhenotypicFeature denotes MPNST D018319
T12 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST D018319
T13 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST D018319
T14 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST D018319

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Neuregulin
T2 22-32 GeneOrGeneProduct denotes neuregulin
T3 35-40 GeneOrGeneProduct denotes alpha
T4 120-126 GeneOrGeneProduct denotes sheath
T5 167-173 GeneOrGeneProduct denotes sheath
T6 237-261 GeneOrGeneProduct denotes neurofibromatosis Type 1
T7 263-266 GeneOrGeneProduct denotes NF1
T8 517-527 GeneOrGeneProduct denotes neuregulin
T9 531-536 GeneOrGeneProduct denotes NRG-1
T10 614-619 GeneOrGeneProduct denotes NRG-1
T11 620-625 GeneOrGeneProduct denotes alpha
T12 709-714 GeneOrGeneProduct denotes NRG-1
T13 727-732 GeneOrGeneProduct denotes NRG-1
T14 733-738 GeneOrGeneProduct denotes alpha
T15 777-782 GeneOrGeneProduct denotes NRG-1
T16 877-884 GeneOrGeneProduct denotes laminin
T17 896-904 GeneOrGeneProduct denotes collagen
T18 915-926 GeneOrGeneProduct denotes fibronectin
T19 932-937 GeneOrGeneProduct denotes NRG-1
T20 948-953 GeneOrGeneProduct denotes erbB3
T21 958-963 GeneOrGeneProduct denotes erbB4
T22 1057-1078 GeneOrGeneProduct denotes focal adhesion kinase
T23 1087-1103 GeneOrGeneProduct denotes laminin receptor
T24 1104-1120 GeneOrGeneProduct denotes beta(1)-integrin
T25 1151-1167 GeneOrGeneProduct denotes beta(1)-integrin
T26 1169-1174 GeneOrGeneProduct denotes NRG-1
T27 1367-1372 GeneOrGeneProduct denotes NRG-1
T28 1443-1448 GeneOrGeneProduct denotes MEK 1
T29 1452-1456 GeneOrGeneProduct denotes SAPK
T30 1462-1473 GeneOrGeneProduct denotes PI-3 kinase
T31 1475-1493 GeneOrGeneProduct denotes Src family kinases
T32 1498-1504 GeneOrGeneProduct denotes ROCK-I
T33 1522-1527 GeneOrGeneProduct denotes NRG-1
T34 1528-1533 GeneOrGeneProduct denotes alpha
T35 1643-1648 GeneOrGeneProduct denotes NRG-1
T36 1690-1697 GeneOrGeneProduct denotes Erk 1/2
T37 1699-1703 GeneOrGeneProduct denotes SAPK
T38 1709-1712 GeneOrGeneProduct denotes Akt
T39 1717-1735 GeneOrGeneProduct denotes Src family kinases
T40 1737-1742 GeneOrGeneProduct denotes NRG-1
T41 1743-1748 GeneOrGeneProduct denotes alpha
T42 1766-1769 GeneOrGeneProduct denotes Akt
T43 1849-1854 GeneOrGeneProduct denotes NRG-1
T44 1906-1911 GeneOrGeneProduct denotes NRG-1
T45 1951-1956 GeneOrGeneProduct denotes NRG-1
T46 1966-1971 GeneOrGeneProduct denotes NRG-1
T47 1972-1977 GeneOrGeneProduct denotes alpha

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor 0017827|0004545|0004345
T4 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors 0017827|0004545|0004345
T7 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs 0017827
T8 210-220 DiseaseOrPhenotypicFeature denotes malignancy 0004992
T9 237-254 DiseaseOrPhenotypicFeature denotes neurofibromatosis 0018975
T10 263-266 DiseaseOrPhenotypicFeature denotes NF1 0018975
T11 352-356 DiseaseOrPhenotypicFeature denotes soft 0013894
T12 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs 0017827
T13 747-752 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T14 797-802 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T15 980-985 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T16 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T17 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T18 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST 0017827

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor D018319
T2 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors D018319
T3 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T4 210-220 DiseaseOrPhenotypicFeature denotes malignancy D009369
T5 237-261 DiseaseOrPhenotypicFeature denotes neurofibromatosis Type 1 D009456
T6 263-266 DiseaseOrPhenotypicFeature denotes NF1 D009456
T7 304-312 DiseaseOrPhenotypicFeature denotes sarcomas D012509
T8 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T9 747-752 DiseaseOrPhenotypicFeature denotes MPNST D018319
T10 797-802 DiseaseOrPhenotypicFeature denotes MPNST D018319
T11 980-985 DiseaseOrPhenotypicFeature denotes MPNST D018319
T12 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST D018319
T13 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST D018319
T14 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST D018319

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor D018319
T2 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors D018319
T3 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T4 210-220 DiseaseOrPhenotypicFeature denotes malignancy D009369
T5 237-261 DiseaseOrPhenotypicFeature denotes neurofibromatosis Type 1 D009456
T6 263-266 DiseaseOrPhenotypicFeature denotes NF1 D009456
T7 304-312 DiseaseOrPhenotypicFeature denotes sarcomas D012509
T8 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T9 747-752 DiseaseOrPhenotypicFeature denotes MPNST D018319
T10 797-802 DiseaseOrPhenotypicFeature denotes MPNST D018319
T11 980-985 DiseaseOrPhenotypicFeature denotes MPNST D018319
T12 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST D018319
T13 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST D018319
T14 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST D018319

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 896-904 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T2 915-926 ChemicalEntity denotes fibronectin http://purl.obolibrary.org/obo/CHEBI_5058
T3 1329-1347 ChemicalEntity denotes chemotactic factor D002630
T4 1443-1446 ChemicalEntity denotes MEK http://purl.obolibrary.org/obo/CHEBI_28398

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 1191-1196 OrganismTaxon denotes human
T2 1201-1207 OrganismTaxon denotes murine

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T4 1443-1446 ChemicalEntity denotes MEK http://purl.obolibrary.org/obo/CHEBI_28398
T3 1329-1347 ChemicalEntity denotes chemotactic factor D002630
T2 915-926 ChemicalEntity denotes fibronectin http://purl.obolibrary.org/obo/CHEBI_5058
T1 896-904 ChemicalEntity denotes collagen http://purl.obolibrary.org/obo/CHEBI_3815
T47 1972-1977 GeneOrGeneProduct denotes alpha
T46 1966-1971 GeneOrGeneProduct denotes NRG-1
T45 1951-1956 GeneOrGeneProduct denotes NRG-1
T44 1906-1911 GeneOrGeneProduct denotes NRG-1
T43 1849-1854 GeneOrGeneProduct denotes NRG-1
T42 1766-1769 GeneOrGeneProduct denotes Akt
T41 1743-1748 GeneOrGeneProduct denotes alpha
T40 1737-1742 GeneOrGeneProduct denotes NRG-1
T39 1717-1735 GeneOrGeneProduct denotes Src family kinases
T38 1709-1712 GeneOrGeneProduct denotes Akt
T37 1699-1703 GeneOrGeneProduct denotes SAPK
T36 1690-1697 GeneOrGeneProduct denotes Erk 1/2
T35 1643-1648 GeneOrGeneProduct denotes NRG-1
T34 1528-1533 GeneOrGeneProduct denotes alpha
T33 1522-1527 GeneOrGeneProduct denotes NRG-1
T32 1498-1504 GeneOrGeneProduct denotes ROCK-I
T31 1475-1493 GeneOrGeneProduct denotes Src family kinases
T30 1462-1473 GeneOrGeneProduct denotes PI-3 kinase
T29 1452-1456 GeneOrGeneProduct denotes SAPK
T28 1443-1448 GeneOrGeneProduct denotes MEK 1
T27 1367-1372 GeneOrGeneProduct denotes NRG-1
T26 1169-1174 GeneOrGeneProduct denotes NRG-1
T25 1151-1167 GeneOrGeneProduct denotes beta(1)-integrin
T24 1104-1120 GeneOrGeneProduct denotes beta(1)-integrin
T23 1087-1103 GeneOrGeneProduct denotes laminin receptor
T22 1057-1078 GeneOrGeneProduct denotes focal adhesion kinase
T21 958-963 GeneOrGeneProduct denotes erbB4
T20 948-953 GeneOrGeneProduct denotes erbB3
T19 932-937 GeneOrGeneProduct denotes NRG-1
T18 915-926 GeneOrGeneProduct denotes fibronectin
T17 896-904 GeneOrGeneProduct denotes collagen
T16 877-884 GeneOrGeneProduct denotes laminin
T15 777-782 GeneOrGeneProduct denotes NRG-1
T14 733-738 GeneOrGeneProduct denotes alpha
T13 727-732 GeneOrGeneProduct denotes NRG-1
T12 709-714 GeneOrGeneProduct denotes NRG-1
T11 620-625 GeneOrGeneProduct denotes alpha
T10 614-619 GeneOrGeneProduct denotes NRG-1
T9 531-536 GeneOrGeneProduct denotes NRG-1
T8 517-527 GeneOrGeneProduct denotes neuregulin
T7 263-266 GeneOrGeneProduct denotes NF1
T6 237-261 GeneOrGeneProduct denotes neurofibromatosis Type 1
T5 167-173 GeneOrGeneProduct denotes sheath
T32657 120-126 GeneOrGeneProduct denotes sheath
T33263 35-40 GeneOrGeneProduct denotes alpha
T23473 22-32 GeneOrGeneProduct denotes neuregulin
T90933 0-10 GeneOrGeneProduct denotes Neuregulin
T69671 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST D018319
T33858 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST D018319
T59168 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST D018319
T47651 980-985 DiseaseOrPhenotypicFeature denotes MPNST D018319
T5286 797-802 DiseaseOrPhenotypicFeature denotes MPNST D018319
T12087 747-752 DiseaseOrPhenotypicFeature denotes MPNST D018319
T41166 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T4425 304-312 DiseaseOrPhenotypicFeature denotes sarcomas D012509
T78011 263-266 DiseaseOrPhenotypicFeature denotes NF1 D009456
T11314 237-261 DiseaseOrPhenotypicFeature denotes neurofibromatosis Type 1 D009456
T28083 210-220 DiseaseOrPhenotypicFeature denotes malignancy D009369
T73529 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs D018319
T20810 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors D018319
T8823 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor D018319
T85484 1201-1207 OrganismTaxon denotes murine
T34054 1191-1196 OrganismTaxon denotes human

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 93-132 DiseaseOrPhenotypicFeature denotes malignant peripheral nerve sheath tumor 0004345|0004545|0017827
T4 140-180 DiseaseOrPhenotypicFeature denotes Malignant peripheral nerve sheath tumors 0004345|0004545|0017827
T7 182-188 DiseaseOrPhenotypicFeature denotes MPNSTs 0004345
T8 210-220 DiseaseOrPhenotypicFeature denotes malignancy 0004992
T9 237-254 DiseaseOrPhenotypicFeature denotes neurofibromatosis 0018975|0021061
T11 263-266 DiseaseOrPhenotypicFeature denotes NF1 0018975
T12 352-356 DiseaseOrPhenotypicFeature denotes soft 0013894
T13 502-508 DiseaseOrPhenotypicFeature denotes MPNSTs 0004345
T14 747-752 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T15 797-802 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T16 980-985 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T17 1208-1213 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T18 1586-1591 DiseaseOrPhenotypicFeature denotes MPNST 0017827
T19 1926-1931 DiseaseOrPhenotypicFeature denotes MPNST 0017827