PubMed:1925397 JSONTXT

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":67},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":68,"end":113},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":114,"end":191},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":192,"end":237},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":238,"end":423},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":424,"end":628},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":629,"end":729},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":730,"end":942},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":67},"obj":"Sentence"},{"id":"T2","span":{"begin":68,"end":113},"obj":"Sentence"},{"id":"T3","span":{"begin":114,"end":191},"obj":"Sentence"},{"id":"T4","span":{"begin":192,"end":237},"obj":"Sentence"},{"id":"T5","span":{"begin":238,"end":423},"obj":"Sentence"},{"id":"T6","span":{"begin":424,"end":628},"obj":"Sentence"},{"id":"T7","span":{"begin":629,"end":729},"obj":"Sentence"},{"id":"T8","span":{"begin":730,"end":942},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"[Evans' syndrome caused by D-penicillamine in rheumatoid arthritis. Value of the corticoids-danazol combination].\nSyndrome d'Evans sous D-pénicillamine au cours d'une polyarthrite rhumatoïde. Intérêt de l'association corticoïdes-danazol.\nThe authors report the development of thrombocytopenia purpura in one patient with seropositive and erosive rheumatoid arthritis treated successfully for 11 months with D-penicillamine. Anti-platelet-bound antibodies were present, but also: anti-erythrocyte antibodies with hemolytic anemia (then defining Evans's syndrome): higher level of antinuclear antibodies; intermittent neutropenia. The responsibility of D-penicillamine is discussed, but thrombocytopenia purpura evolved for itself. Glucocorticoids alone, intravenous immunoglobulin, vincristine did not induced remission, which at least occurred under the association danazol-glucocorticoids, without toxicity, especially on the liver function."}

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{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":927,"end":932},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"[Evans' syndrome caused by D-penicillamine in rheumatoid arthritis. Value of the corticoids-danazol combination].\nSyndrome d'Evans sous D-pénicillamine au cours d'une polyarthrite rhumatoïde. Intérêt de l'association corticoïdes-danazol.\nThe authors report the development of thrombocytopenia purpura in one patient with seropositive and erosive rheumatoid arthritis treated successfully for 11 months with D-penicillamine. Anti-platelet-bound antibodies were present, but also: anti-erythrocyte antibodies with hemolytic anemia (then defining Evans's syndrome): higher level of antinuclear antibodies; intermittent neutropenia. The responsibility of D-penicillamine is discussed, but thrombocytopenia purpura evolved for itself. Glucocorticoids alone, intravenous immunoglobulin, vincristine did not induced remission, which at least occurred under the association danazol-glucocorticoids, without toxicity, especially on the liver function."}

{"project":"QFMC_MEDLINE","denotations":[{"id":"T1","span":{"begin":114,"end":130},"obj":"DISO"},{"id":"T1c","span":{"begin":114,"end":130},"obj":"UMLS:C0272126"},{"id":"T2","span":{"begin":114,"end":122},"obj":"DISO"},{"id":"T2c","span":{"begin":114,"end":122},"obj":"UMLS:C0039082"},{"id":"T3","span":{"begin":136,"end":151},"obj":"CHEM"},{"id":"T3c","span":{"begin":136,"end":151},"obj":"UMLS:C0030817"},{"id":"T4","span":{"begin":167,"end":190},"obj":"DISO"},{"id":"T4c","span":{"begin":167,"end":190},"obj":"UMLS:C0003873"},{"id":"T5","span":{"begin":167,"end":179},"obj":"DISO"},{"id":"T5c","span":{"begin":167,"end":179},"obj":"UMLS:C0003864"},{"id":"T6","span":{"begin":180,"end":190},"obj":"DISO"},{"id":"T6c","span":{"begin":180,"end":190},"obj":"UMLS:C0035435"}],"relations":[{"id":"#1","pred":"Normalization","subj":"T1","obj":"T1c"},{"id":"#2","pred":"Normalization","subj":"T2","obj":"T2c"},{"id":"#3","pred":"Normalization","subj":"T3","obj":"T3c"},{"id":"#4","pred":"Normalization","subj":"T4","obj":"T4c"},{"id":"#5","pred":"Normalization","subj":"T5","obj":"T5c"},{"id":"#6","pred":"Normalization","subj":"T6","obj":"T6c"}],"namespaces":[{"prefix":"UMLS","uri":"https://uts.nlm.nih.gov/metathesaurus.html#"}],"text":"[Evans' syndrome caused by D-penicillamine in rheumatoid arthritis. Value of the corticoids-danazol combination].\nSyndrome d'Evans sous D-pénicillamine au cours d'une polyarthrite rhumatoïde. Intérêt de l'association corticoïdes-danazol.\nThe authors report the development of thrombocytopenia purpura in one patient with seropositive and erosive rheumatoid arthritis treated successfully for 11 months with D-penicillamine. Anti-platelet-bound antibodies were present, but also: anti-erythrocyte antibodies with hemolytic anemia (then defining Evans's syndrome): higher level of antinuclear antibodies; intermittent neutropenia. The responsibility of D-penicillamine is discussed, but thrombocytopenia purpura evolved for itself. Glucocorticoids alone, intravenous immunoglobulin, vincristine did not induced remission, which at least occurred under the association danazol-glucocorticoids, without toxicity, especially on the liver function."}