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CL-cell

Id	Subject	Object	Predicate	Lexical cue	cl_id
T1	425-435	Cell	denotes	leukocytes	http://purl.obolibrary.org/obo/CL:0000738
T2	575-583	Cell	denotes	monocyte	http://purl.obolibrary.org/obo/CL:0000576\|http://purl.obolibrary.org/obo/CL:0001054
T4	614-624	Cell	denotes	macrophage	http://purl.obolibrary.org/obo/CL:0000235\|http://purl.obolibrary.org/obo/CL:0000394
T6	653-661	Cell	denotes	monocyte	http://purl.obolibrary.org/obo/CL:0000576\|http://purl.obolibrary.org/obo/CL:0001054
T8	775-786	Cell	denotes	neutrophils	http://purl.obolibrary.org/obo/CL:0000775
T9	788-799	Cell	denotes	lymphocytes	http://purl.obolibrary.org/obo/CL:0000542
T10	805-816	Cell	denotes	macrophages	http://purl.obolibrary.org/obo/CL:0000235\|http://purl.obolibrary.org/obo/CL:0000394
T12	1182-1192	Cell	denotes	leukocytes	http://purl.obolibrary.org/obo/CL:0000738

Inflammaging

Id	Subject	Object	Predicate	Lexical cue
T1	0-127	Sentence	denotes	GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
T2	128-288	Sentence	denotes	We describe novel, cell-permeable, and bioavailable salicylic acid derivatives that are potent and selective inhibitors of GLEPP1/protein-tyrosine phosphatase .
T3	289-450	Sentence	denotes	Two previously described GLEPP1 substrates, paxillin and Syk, are both required for cytoskeletal rearrangement and cellular motility of leukocytes in chemotaxis.
T4	451-684	Sentence	denotes	We show here that GLEPP1 inhibitors prevent dephosphorylation of Syk1 and paxillin in resting cells and block primary human monocyte and mouse bone marrow-derived macrophage chemotaxis in a gradient of monocyte chemotactic protein-1.
T5	685-817	Sentence	denotes	In mice, the GLEPP1 inhibitors also reduce thioglycolate-induced peritoneal chemotaxis of neutrophils, lymphocytes, and macrophages.
T6	818-1052	Sentence	denotes	In murine disease models, the GLEPP1 inhibitors significantly reduce severity of contact hypersensitivity, a model for allergic dermatitis, and dextran sulfate sodium-induced ulcerative colitis, a model for inflammatory bowel disease.
T7	1053-1274	Sentence	denotes	Taken together, our data provide confirmation that GLEPP1 plays an important role in controlling chemotaxis of multiple types of leukocytes and that pharmacological inhibition of this phosphatase may have therapeutic use.
T1	0-127	Sentence	denotes	GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
T2	128-288	Sentence	denotes	We describe novel, cell-permeable, and bioavailable salicylic acid derivatives that are potent and selective inhibitors of GLEPP1/protein-tyrosine phosphatase .
T3	289-450	Sentence	denotes	Two previously described GLEPP1 substrates, paxillin and Syk, are both required for cytoskeletal rearrangement and cellular motility of leukocytes in chemotaxis.
T4	451-684	Sentence	denotes	We show here that GLEPP1 inhibitors prevent dephosphorylation of Syk1 and paxillin in resting cells and block primary human monocyte and mouse bone marrow-derived macrophage chemotaxis in a gradient of monocyte chemotactic protein-1.
T5	685-817	Sentence	denotes	In mice, the GLEPP1 inhibitors also reduce thioglycolate-induced peritoneal chemotaxis of neutrophils, lymphocytes, and macrophages.
T6	818-1052	Sentence	denotes	In murine disease models, the GLEPP1 inhibitors significantly reduce severity of contact hypersensitivity, a model for allergic dermatitis, and dextran sulfate sodium-induced ulcerative colitis, a model for inflammatory bowel disease.
T7	1053-1274	Sentence	denotes	Taken together, our data provide confirmation that GLEPP1 plays an important role in controlling chemotaxis of multiple types of leukocytes and that pharmacological inhibition of this phosphatase may have therapeutic use.

PMID_GLOBAL

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	108-126	DiseaseOrPhenotypicFeature	denotes	ulcerative colitis	0005101\|0009960
T3	907-923	DiseaseOrPhenotypicFeature	denotes	hypersensitivity	0000605\|0005271
T5	937-956	DiseaseOrPhenotypicFeature	denotes	allergic dermatitis	0004980
T6	993-1011	DiseaseOrPhenotypicFeature	denotes	ulcerative colitis	0005101\|0009960
T8	1025-1051	DiseaseOrPhenotypicFeature	denotes	inflammatory bowel disease	0005265

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-127	Sentence	denotes	GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
T2	128-288	Sentence	denotes	We describe novel, cell-permeable, and bioavailable salicylic acid derivatives that are potent and selective inhibitors of GLEPP1/protein-tyrosine phosphatase .
T3	289-450	Sentence	denotes	Two previously described GLEPP1 substrates, paxillin and Syk, are both required for cytoskeletal rearrangement and cellular motility of leukocytes in chemotaxis.
T4	451-684	Sentence	denotes	We show here that GLEPP1 inhibitors prevent dephosphorylation of Syk1 and paxillin in resting cells and block primary human monocyte and mouse bone marrow-derived macrophage chemotaxis in a gradient of monocyte chemotactic protein-1.
T5	685-817	Sentence	denotes	In mice, the GLEPP1 inhibitors also reduce thioglycolate-induced peritoneal chemotaxis of neutrophils, lymphocytes, and macrophages.
T6	818-1052	Sentence	denotes	In murine disease models, the GLEPP1 inhibitors significantly reduce severity of contact hypersensitivity, a model for allergic dermatitis, and dextran sulfate sodium-induced ulcerative colitis, a model for inflammatory bowel disease.
T7	1053-1274	Sentence	denotes	Taken together, our data provide confirmation that GLEPP1 plays an important role in controlling chemotaxis of multiple types of leukocytes and that pharmacological inhibition of this phosphatase may have therapeutic use.
T1	0-127	Sentence	denotes	GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
T2	128-288	Sentence	denotes	We describe novel, cell-permeable, and bioavailable salicylic acid derivatives that are potent and selective inhibitors of GLEPP1/protein-tyrosine phosphatase .
T3	289-450	Sentence	denotes	Two previously described GLEPP1 substrates, paxillin and Syk, are both required for cytoskeletal rearrangement and cellular motility of leukocytes in chemotaxis.
T4	451-684	Sentence	denotes	We show here that GLEPP1 inhibitors prevent dephosphorylation of Syk1 and paxillin in resting cells and block primary human monocyte and mouse bone marrow-derived macrophage chemotaxis in a gradient of monocyte chemotactic protein-1.
T5	685-817	Sentence	denotes	In mice, the GLEPP1 inhibitors also reduce thioglycolate-induced peritoneal chemotaxis of neutrophils, lymphocytes, and macrophages.
T6	818-1052	Sentence	denotes	In murine disease models, the GLEPP1 inhibitors significantly reduce severity of contact hypersensitivity, a model for allergic dermatitis, and dextran sulfate sodium-induced ulcerative colitis, a model for inflammatory bowel disease.
T7	1053-1274	Sentence	denotes	Taken together, our data provide confirmation that GLEPP1 plays an important role in controlling chemotaxis of multiple types of leukocytes and that pharmacological inhibition of this phosphatase may have therapeutic use.

Glycosmos6-MAT

Id	Subject	Object	Predicate	Lexical cue
T1	594-605	http://purl.obolibrary.org/obo/MAT_0000084	denotes	bone marrow
T2	594-598	http://purl.obolibrary.org/obo/MAT_0000299	denotes	bone

Anatomy-MAT

Id	Subject	Object	Predicate	Lexical cue	mat_id
T1	594-605	Body_part	denotes	bone marrow	http://purl.obolibrary.org/obo/MAT_0000084

HP-phenotype

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	108-126	Phenotype	denotes	ulcerative colitis	HP:0100279
T2	907-923	Phenotype	denotes	hypersensitivity	HP:0041092
T3	946-956	Phenotype	denotes	dermatitis	HP:0011123
T4	993-1011	Phenotype	denotes	ulcerative colitis	HP:0100279
T5	1025-1051	Phenotype	denotes	inflammatory bowel disease	HP:0002037

mondo_disease

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	108-126	Disease	denotes	ulcerative colitis	http://purl.obolibrary.org/obo/MONDO_0005101\|http://purl.obolibrary.org/obo/MONDO_0009960
T3	907-923	Disease	denotes	hypersensitivity	http://purl.obolibrary.org/obo/MONDO_0000605\|http://purl.obolibrary.org/obo/MONDO_0005271
T5	937-956	Disease	denotes	allergic dermatitis	http://purl.obolibrary.org/obo/MONDO_0004980
T6	993-1011	Disease	denotes	ulcerative colitis	http://purl.obolibrary.org/obo/MONDO_0005101\|http://purl.obolibrary.org/obo/MONDO_0009960
T8	1025-1051	Disease	denotes	inflammatory bowel disease	http://purl.obolibrary.org/obo/MONDO_0005265

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	569-574	OrganismTaxon	denotes	human	9606
T2	588-593	OrganismTaxon	denotes	mouse	10088\|10090
T4	688-692	OrganismTaxon	denotes	mice	10088

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	425-435	Body_part	denotes	leukocytes	http://purl.obolibrary.org/obo/CL_0000738
T2	575-583	Body_part	denotes	monocyte	http://purl.obolibrary.org/obo/CL_0000576\|http://purl.obolibrary.org/obo/CL_0001054
T4	594-605	Body_part	denotes	bone marrow	http://purl.obolibrary.org/obo/UBERON_0002371
T5	614-624	Body_part	denotes	macrophage	http://purl.obolibrary.org/obo/CL_0000235
T6	653-661	Body_part	denotes	monocyte	http://purl.obolibrary.org/obo/CL_0000576\|http://purl.obolibrary.org/obo/CL_0001054
T8	775-786	Body_part	denotes	neutrophils	http://purl.obolibrary.org/obo/CL_0000775
T9	788-799	Body_part	denotes	lymphocytes	http://purl.obolibrary.org/obo/CL_0000542
T10	805-816	Body_part	denotes	macrophages	http://purl.obolibrary.org/obo/CL_0000235
T11	1038-1043	Body_part	denotes	bowel	http://purl.obolibrary.org/obo/UBERON_0000160
T12	1182-1192	Body_part	denotes	leukocytes	http://purl.obolibrary.org/obo/CL_0000738