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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-105 Sentence denotes The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias.
T2 106-108 Sentence denotes 1.
T3 109-219 Sentence denotes The optical isomers of propranolol have been compared for their beta-blocking and antiarrhythmic activities.2.
T4 220-374 Sentence denotes In blocking the positive inotropic and chronotropic responses to isoprenaline, (+)-propranolol had less than one hundredth the potency of (-)-propranolol.
T5 375-540 Sentence denotes At dose levels of (+)-propranolol which attenuated the responses to isoprenaline, there was a significant prolongation of the PR interval of the electrocardiogram.3.
T6 541-821 Sentence denotes The metabolic responses to isoprenaline in dogs (an increase in circulating glucose, lactate and free fatty acids) were all blocked by (-)-propranolol. (+)-Propranolol had no effect on fatty acid mobilization but significantly reduced the increments in both lactate and glucose.4.
T7 822-938 Sentence denotes Both isomers of propranolol possessed similar depressant potency on isolated atrial muscle taken from guinea-pigs.5.
T8 939-1104 Sentence denotes The isomers of propranolol exhibited similar local anaesthetic potencies on an isolated frog nerve preparation at a level approximately three times that of procaine.
T9 1105-1177 Sentence denotes The racemic compound was significantly less potent than either isomer.6.
T10 1178-1421 Sentence denotes Both isomers of propranolol were capable of preventing adrenaline-induced cardiac arrhythmias in cats anaesthetized with halothane, but the mean dose of (-)-propranolol was 0.09+/-0.02 mg/kg whereas that of (+)-propranolol was 4.2+/-1.2 mg/kg.
T11 1422-1550 Sentence denotes At the effective dose level of (+)-propranolol there was a significant prolongation of the PR interval of the electrocardiogram.
T12 1551-1649 Sentence denotes Blockade of arrhythmias with both isomers was surmountable by increasing the dose of adrenaline.7.
T13 1650-1782 Sentence denotes Both isomers of propranolol were also capable of reversing ventricular tachycardia caused by ouabain in anaesthetized cats and dogs.
T14 1783-1956 Sentence denotes The dose of (-)-propranolol was significantly smaller than that of (+)-propranolol in both species but much higher than that required to produce evidence of beta-blockade.8.
T15 1957-2005 Sentence denotes The implications of these results are discussed.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 584-588 OrganismTaxon denotes dogs NCBItxid:9615
T2 924-935 OrganismTaxon denotes guinea-pigs NCBItxid:10140
T3 1275-1279 OrganismTaxon denotes cats NCBItxid:9685
T4 1768-1772 OrganismTaxon denotes cats NCBItxid:9685
T5 1777-1781 OrganismTaxon denotes dogs NCBItxid:9615

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
5674 52-63 ChemicalEntity denotes propranolol MESH:D011433
5675 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias MESH:D001145
5676 132-143 ChemicalEntity denotes propranolol MESH:D011433
5677 285-297 ChemicalEntity denotes isoprenaline MESH:D007545
5678 303-314 ChemicalEntity denotes propranolol MESH:D011433
5679 362-373 ChemicalEntity denotes propranolol MESH:D011433
5680 397-408 ChemicalEntity denotes propranolol MESH:D011433
5681 443-455 ChemicalEntity denotes isoprenaline MESH:D007545
5682 568-580 ChemicalEntity denotes isoprenaline MESH:D007545
5683 584-588 OrganismTaxon denotes dogs NCBITaxon:9615
5684 617-624 ChemicalEntity denotes glucose MESH:D005947
5685 626-633 ChemicalEntity denotes lactate MESH:D019344
5686 643-654 ChemicalEntity denotes fatty acids MESH:D005227
5687 680-691 ChemicalEntity denotes propranolol MESH:D011433
5688 697-708 ChemicalEntity denotes Propranolol MESH:D011433
5689 726-736 ChemicalEntity denotes fatty acid MESH:D005227
5690 799-806 ChemicalEntity denotes lactate MESH:D019344
5691 811-818 ChemicalEntity denotes glucose MESH:D005947
5692 838-849 ChemicalEntity denotes propranolol MESH:D011433
5693 924-935 OrganismTaxon denotes guinea-pigs NCBITaxon:10141
5694 954-965 ChemicalEntity denotes propranolol MESH:D011433
5695 1095-1103 ChemicalEntity denotes procaine MESH:D011343
5696 1194-1205 ChemicalEntity denotes propranolol MESH:D011433
5697 1233-1243 ChemicalEntity denotes adrenaline MESH:D004837
5698 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias MESH:D001145
5699 1275-1279 OrganismTaxon denotes cats NCBITaxon:9685
5700 1299-1308 ChemicalEntity denotes halothane MESH:D006221
5701 1335-1346 ChemicalEntity denotes propranolol MESH:D011433
5702 1389-1400 ChemicalEntity denotes propranolol MESH:D011433
5703 1457-1468 ChemicalEntity denotes propranolol MESH:D011433
5704 1563-1574 DiseaseOrPhenotypicFeature denotes arrhythmias MESH:D001145
5705 1636-1646 ChemicalEntity denotes adrenaline MESH:D004837
5706 1666-1677 ChemicalEntity denotes propranolol MESH:D011433
5707 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia MESH:D017180
5708 1743-1750 ChemicalEntity denotes ouabain MESH:D010042
5709 1768-1772 OrganismTaxon denotes cats NCBITaxon:9685
5710 1777-1781 OrganismTaxon denotes dogs NCBITaxon:9615
5711 1799-1810 ChemicalEntity denotes propranolol MESH:D011433
5712 1854-1865 ChemicalEntity denotes propranolol MESH:D011433

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia 0005477

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 173-177 GeneOrGeneProduct denotes beta
T2 178-190 GeneOrGeneProduct denotes blocking and
T3 206-218 GeneOrGeneProduct denotes activities.2
T4 223-231 GeneOrGeneProduct denotes blocking
T5 415-425 GeneOrGeneProduct denotes attenuated
T6 643-648 GeneOrGeneProduct denotes fatty
T7 649-654 GeneOrGeneProduct denotes acids
T8 661-664 GeneOrGeneProduct denotes all
T9 665-672 GeneOrGeneProduct denotes blocked
T10 726-731 GeneOrGeneProduct denotes fatty
T11 732-736 GeneOrGeneProduct denotes acid
T12 768-775 GeneOrGeneProduct denotes reduced
T13 860-867 GeneOrGeneProduct denotes similar
T14 868-878 GeneOrGeneProduct denotes depressant
T15 906-912 GeneOrGeneProduct denotes muscle
T16 931-935 GeneOrGeneProduct denotes pigs
T17 976-983 GeneOrGeneProduct denotes similar
T18 1061-1074 GeneOrGeneProduct denotes approximately
T19 1081-1086 GeneOrGeneProduct denotes times
T20 1211-1218 GeneOrGeneProduct denotes capable
T21 1244-1251 GeneOrGeneProduct denotes induced
T22 1275-1279 GeneOrGeneProduct denotes cats
T23 1299-1308 GeneOrGeneProduct denotes halothane
T24 1363-1365 GeneOrGeneProduct denotes mg
T25 1415-1417 GeneOrGeneProduct denotes mg
T26 1688-1695 GeneOrGeneProduct denotes capable
T27 1768-1772 GeneOrGeneProduct denotes cats
T28 1829-1836 GeneOrGeneProduct denotes smaller
T29 1940-1944 GeneOrGeneProduct denotes beta

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 173-177 GeneOrGeneProduct denotes beta
T2 415-425 GeneOrGeneProduct denotes attenuated
T3 665-672 GeneOrGeneProduct denotes blocked
T4 732-736 GeneOrGeneProduct denotes acid
T5 768-775 GeneOrGeneProduct denotes reduced
T6 860-867 GeneOrGeneProduct denotes similar
T7 906-912 GeneOrGeneProduct denotes muscle
T8 931-935 GeneOrGeneProduct denotes pigs
T9 976-983 GeneOrGeneProduct denotes similar
T10 1275-1279 GeneOrGeneProduct denotes cats
T11 1299-1308 GeneOrGeneProduct denotes halothane
T12 1768-1772 GeneOrGeneProduct denotes cats
T13 1829-1836 GeneOrGeneProduct denotes smaller
T14 1940-1944 GeneOrGeneProduct denotes beta

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T2 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T3 1563-1574 DiseaseOrPhenotypicFeature denotes arrhythmias D001145
T4 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia D017180

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 931-935 GeneOrGeneProduct denotes pigs
T2 1299-1308 GeneOrGeneProduct denotes halothane

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias 0020745
T2 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias 0020745
T3 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia 0005477

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T2 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T3 1563-1574 DiseaseOrPhenotypicFeature denotes arrhythmias D001145
T4 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia D017180

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T2 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T3 1563-1574 DiseaseOrPhenotypicFeature denotes arrhythmias D001145
T4 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia D017180

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 52-63 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T3 132-143 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T5 285-297 ChemicalEntity denotes isoprenaline D007545|http://purl.obolibrary.org/obo/CHEBI_64317
T7 303-314 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T9 362-373 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T11 397-408 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T13 443-455 ChemicalEntity denotes isoprenaline D007545|http://purl.obolibrary.org/obo/CHEBI_64317
T15 568-580 ChemicalEntity denotes isoprenaline D007545|http://purl.obolibrary.org/obo/CHEBI_64317
T17 617-624 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T20 626-633 ChemicalEntity denotes lactate D019344|http://purl.obolibrary.org/obo/CHEBI_24996
T22 638-654 ChemicalEntity denotes free fatty acids D005230
T23 680-691 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T25 697-708 ChemicalEntity denotes Propranolol http://purl.obolibrary.org/obo/CHEBI_8499
T26 799-806 ChemicalEntity denotes lactate D019344|http://purl.obolibrary.org/obo/CHEBI_24996
T28 811-818 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T31 838-849 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T33 954-965 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T35 1095-1103 ChemicalEntity denotes procaine D011343|http://purl.obolibrary.org/obo/CHEBI_8430
T37 1194-1205 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T39 1233-1243 ChemicalEntity denotes adrenaline D004837|http://purl.obolibrary.org/obo/CHEBI_33568|http://purl.obolibrary.org/obo/CHEBI_28918
T42 1299-1308 ChemicalEntity denotes halothane D006221|http://purl.obolibrary.org/obo/CHEBI_5615
T44 1335-1346 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T46 1389-1400 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T48 1457-1468 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T50 1636-1646 ChemicalEntity denotes adrenaline D004837|http://purl.obolibrary.org/obo/CHEBI_33568|http://purl.obolibrary.org/obo/CHEBI_28918
T53 1666-1677 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T55 1743-1750 ChemicalEntity denotes ouabain D010042|http://purl.obolibrary.org/obo/CHEBI_472805|http://purl.obolibrary.org/obo/CHEBI_145798
T58 1799-1810 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499
T60 1854-1865 ChemicalEntity denotes propranolol D011433|http://purl.obolibrary.org/obo/CHEBI_8499

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 584-588 OrganismTaxon denotes dogs
T2 924-935 OrganismTaxon denotes guinea-pigs
T3 1275-1279 OrganismTaxon denotes cats
T4 1768-1772 OrganismTaxon denotes cats
T5 1777-1781 OrganismTaxon denotes dogs

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T60 1854-1865 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T58 1799-1810 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T55 1743-1750 ChemicalEntity denotes ouabain http://purl.obolibrary.org/obo/CHEBI_145798|http://purl.obolibrary.org/obo/CHEBI_472805|D010042
T53 1666-1677 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T50 1636-1646 ChemicalEntity denotes adrenaline http://purl.obolibrary.org/obo/CHEBI_28918|http://purl.obolibrary.org/obo/CHEBI_33568|D004837
T48 1457-1468 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T46 1389-1400 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T44 1335-1346 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T42 1299-1308 ChemicalEntity denotes halothane http://purl.obolibrary.org/obo/CHEBI_5615|D006221
T39 1233-1243 ChemicalEntity denotes adrenaline http://purl.obolibrary.org/obo/CHEBI_28918|http://purl.obolibrary.org/obo/CHEBI_33568|D004837
T37 1194-1205 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T35 1095-1103 ChemicalEntity denotes procaine http://purl.obolibrary.org/obo/CHEBI_8430|D011343
T33 954-965 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T31 838-849 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T28 811-818 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T26 799-806 ChemicalEntity denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996|D019344
T25 697-708 ChemicalEntity denotes Propranolol http://purl.obolibrary.org/obo/CHEBI_8499
T23 680-691 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T22 638-654 ChemicalEntity denotes free fatty acids D005230
T20 626-633 ChemicalEntity denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996|D019344
T17 617-624 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T15 568-580 ChemicalEntity denotes isoprenaline http://purl.obolibrary.org/obo/CHEBI_64317|D007545
T13 443-455 ChemicalEntity denotes isoprenaline http://purl.obolibrary.org/obo/CHEBI_64317|D007545
T11 397-408 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T9 362-373 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T7 303-314 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T5 285-297 ChemicalEntity denotes isoprenaline http://purl.obolibrary.org/obo/CHEBI_64317|D007545
T3 132-143 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T1 52-63 ChemicalEntity denotes propranolol http://purl.obolibrary.org/obo/CHEBI_8499|D011433
T2 1299-1308 GeneOrGeneProduct denotes halothane
T94764 931-935 GeneOrGeneProduct denotes pigs
T4 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia D017180
T50539 1563-1574 DiseaseOrPhenotypicFeature denotes arrhythmias D001145
T18381 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T96478 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias D001145
T78669 1777-1781 OrganismTaxon denotes dogs
T29524 1768-1772 OrganismTaxon denotes cats
T56600 1275-1279 OrganismTaxon denotes cats
T92566 924-935 OrganismTaxon denotes guinea-pigs
T15631 584-588 OrganismTaxon denotes dogs

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 85-104 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias 0020745
T2 1252-1271 DiseaseOrPhenotypicFeature denotes cardiac arrhythmias 0020745
T3 1709-1732 DiseaseOrPhenotypicFeature denotes ventricular tachycardia 0005477