PubMed:19048115 / 0-248 JSONTXT

{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":109},"obj":"Sentence"},{"id":"T2","span":{"begin":110,"end":220},"obj":"Sentence"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":44,"end":49},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:9606"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-entities","denotations":[{"id":"5551","span":{"begin":0,"end":15},"obj":"GeneOrGeneProduct"},{"id":"5552","span":{"begin":17,"end":20},"obj":"GeneOrGeneProduct"},{"id":"5553","span":{"begin":44,"end":49},"obj":"OrganismTaxon"},{"id":"5554","span":{"begin":50,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"5555","span":{"begin":94,"end":98},"obj":"GeneOrGeneProduct"},{"id":"5556","span":{"begin":110,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"5557","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"5558","span":{"begin":190,"end":219},"obj":"DiseaseOrPhenotypicFeature"},{"id":"5559","span":{"begin":234,"end":238},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A1","pred":"db_id","subj":"5551","obj":"NCBIGene:4763"},{"id":"A2","pred":"db_id","subj":"5552","obj":"NCBIGene:4763"},{"id":"A3","pred":"db_id","subj":"5553","obj":"NCBITaxon:9606"},{"id":"A4","pred":"db_id","subj":"5554","obj":"MESH:D010051"},{"id":"A5","pred":"db_id","subj":"5555","obj":"NCBIGene:7157"},{"id":"A6","pred":"db_id","subj":"5556","obj":"MESH:D010051"},{"id":"A7","pred":"db_id","subj":"5557","obj":"MESH:D010051"},{"id":"A8","pred":"db_id","subj":"5558","obj":"MESH:D002277"},{"id":"A9","pred":"db_id","subj":"5559","obj":"NCBIGene:7157"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":65,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":125,"end":134},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0004993"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0004993"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":0,"end":15},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":17,"end":20},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":22,"end":33},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":94,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":99,"end":108},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":136,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":164,"end":170},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":221,"end":230},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":234,"end":238},"obj":"GeneOrGeneProduct"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":0,"end":15},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":17,"end":20},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":94,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":136,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":164,"end":170},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":234,"end":238},"obj":"GeneOrGeneProduct"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":65,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":125,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D002277"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D002277"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D009369"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":0,"end":15},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":17,"end":20},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":94,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":136,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":234,"end":238},"obj":"GeneOrGeneProduct"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":17,"end":20},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":50,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":110,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0018975"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0005211"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0005211"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0005211"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0004992"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":65,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":125,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D002277"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D002277"},{"id":"A3","pred":"ID:","subj":"T3","obj":"DISEASE"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D009369"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":65,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":125,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D002277"},{"id":"A2","pred":"#label","subj":"T2","obj":"D002277"},{"id":"A3","pred":"#label","subj":"T3","obj":"DISEASE"},{"id":"A4","pred":"#label","subj":"T4","obj":"D009369"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":44,"end":49},"obj":"OrganismTaxon"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"LitCoin-training-merged","denotations":[{"id":"T5","span":{"begin":234,"end":238},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":136,"end":139},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":94,"end":98},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":17,"end":20},"obj":"GeneOrGeneProduct"},{"id":"T7660","span":{"begin":0,"end":15},"obj":"GeneOrGeneProduct"},{"id":"T43052","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10879","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T69314","span":{"begin":125,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T67918","span":{"begin":65,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T37895","span":{"begin":44,"end":49},"obj":"OrganismTaxon"}],"attributes":[{"id":"A4","pred":"#label","subj":"T43052","obj":"D009369"},{"id":"A3","pred":"#label","subj":"T10879","obj":"DISEASE"},{"id":"A9156","pred":"#label","subj":"T69314","obj":"D002277"},{"id":"A717","pred":"#label","subj":"T67918","obj":"D002277"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"PMID_GLOBAL","denotations":[{"id":"T1","span":{"begin":17,"end":20},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":50,"end":75},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":110,"end":134},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":136,"end":139},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":209,"end":219},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0018975"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0005211"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0005211"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0005211"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0004992"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"19048115-2#13#17#gene7157","span":{"begin":234,"end":238},"obj":"gene7157"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}

{"project":"CoMAGC","denotations":[{"id":"T1","span":{"begin":0,"end":15},"obj":"Gene"},{"id":"E2","span":{"begin":22,"end":29},"obj":"Negative_regulation"},{"id":"T2","span":{"begin":50,"end":75},"obj":"ovarian cancer"}],"relations":[{"id":"R1","pred":"themeOf","subj":"T1","obj":"E2"},{"id":"R3","pred":"CGE-decreased","subj":"T1","obj":"T2"},{"id":"R4","pred":"CCS-normalTOcancer","subj":"T1","obj":"T2"},{"id":"R5","pred":"PT-observation","subj":"T1","obj":"T2"},{"id":"R3","pred":"IGE-unchanged","subj":"T1","obj":"T2"}],"text":"Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations.\nOvarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfu"}