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PubMed:18853255 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 842-844 DiseaseOrPhenotypicFeature denotes HT 0007699
T2 939-943 DiseaseOrPhenotypicFeature denotes rich 0015404

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-71 Sentence denotes Specific oligomerization of the 5-HT1A receptor in the plasma membrane.
TextSentencer_T2 72-193 Sentence denotes In the present study we analyze the oligomerization of the 5-HT1A receptor within living cells at the sub-cellular level.
TextSentencer_T3 194-481 Sentence denotes Using a 2-excitation Förster Resonance Energy Transfer (FRET) method combined with spectral microscopy we are able to estimate the efficiency of energy transfer based on donor quenching as well as acceptor sensitization between CFP-and YFP-tagged 5-HT1A receptors at the plasma membrane.
TextSentencer_T4 482-725 Sentence denotes Through the analysis of the level of apparent FRET efficiency over the various relative amounts of donor and acceptor, as well as over a range of total surface expressions of the receptor, we verify the specific interaction of these receptors.
TextSentencer_T5 726-865 Sentence denotes Furthermore we study the role of acylation in this interaction through measurements of a palmitoylation-deficient 5-HT(1A) receptor mutant.
TextSentencer_T6 866-980 Sentence denotes Palmitoylation increases the tendency of a receptor to localize in lipid rich microdomains of the plasma membrane.
TextSentencer_T7 981-1100 Sentence denotes This increases the effective surface density of the receptor and provides for a higher level of stochastic interaction.
T1 0-71 Sentence denotes Specific oligomerization of the 5-HT1A receptor in the plasma membrane.
T2 72-193 Sentence denotes In the present study we analyze the oligomerization of the 5-HT1A receptor within living cells at the sub-cellular level.
T3 194-481 Sentence denotes Using a 2-excitation Förster Resonance Energy Transfer (FRET) method combined with spectral microscopy we are able to estimate the efficiency of energy transfer based on donor quenching as well as acceptor sensitization between CFP-and YFP-tagged 5-HT1A receptors at the plasma membrane.
T4 482-725 Sentence denotes Through the analysis of the level of apparent FRET efficiency over the various relative amounts of donor and acceptor, as well as over a range of total surface expressions of the receptor, we verify the specific interaction of these receptors.
T5 726-865 Sentence denotes Furthermore we study the role of acylation in this interaction through measurements of a palmitoylation-deficient 5-HT(1A) receptor mutant.
T6 866-980 Sentence denotes Palmitoylation increases the tendency of a receptor to localize in lipid rich microdomains of the plasma membrane.
T7 981-1100 Sentence denotes This increases the effective surface density of the receptor and provides for a higher level of stochastic interaction.

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 55-70 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T2 465-480 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T3 964-979 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886