PubMed:18849583
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 107-134 | DiseaseOrPhenotypicFeature | denotes | Primary open angle glaucoma | 0007665 |
| T2 | 136-140 | DiseaseOrPhenotypicFeature | denotes | POAG | 0007665 |
| T3 | 153-162 | DiseaseOrPhenotypicFeature | denotes | blindness | 0001941 |
| T4 | 1247-1250 | DiseaseOrPhenotypicFeature | denotes | CRD | 0009528 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-106 | Sentence | denotes | The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. |
| TextSentencer_T2 | 107-275 | Sentence | denotes | Primary open angle glaucoma (POAG) is a major blindness-causing disease, characterized by elevated intraocular pressure due to an insufficient outflow of aqueous humor. |
| TextSentencer_T3 | 276-379 | Sentence | denotes | The trabecular meshwork (TM) lining the aqueous outflow pathway modulates the aqueous outflow facility. |
| TextSentencer_T4 | 380-549 | Sentence | denotes | TM cell adhesion, cell-matrix interactions, and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. |
| TextSentencer_T5 | 550-756 | Sentence | denotes | In a recent study, we demonstrated that galectin-8 (Gal8) modulates the adhesion and cytoskeletal arrangement of TM cells and that it does so through binding to beta(1) integrins and inducing Rho signaling. |
| TextSentencer_T6 | 757-879 | Sentence | denotes | The current study is aimed at the characterization of the mechanism by which Gal8 mediates TM cell adhesion and spreading. |
| TextSentencer_T7 | 880-1020 | Sentence | denotes | We demonstrate here that TM cells adhere to and spread on Gal8-coated wells but not on galectin-1 (Gal1)- or galectin-3 (Gal3)-coated wells. |
| TextSentencer_T8 | 1021-1158 | Sentence | denotes | The adhesion of TM cells to Gal8-coated wells was abolished by a competing sugar, beta-lactose, but not by a noncompeting sugar, sucrose. |
| TextSentencer_T9 | 1159-1317 | Sentence | denotes | Also, a trisaccharide, NeuAcalpha2-3Galbeta1-4GlcNAc, which binds specifically to the N-CRD of Gal8, inhibited the spreading of TM cells to Gal8-coated wells. |
| TextSentencer_T10 | 1318-1405 | Sentence | denotes | In contrast, NeuAcalpha2-6Galbeta1-4GlcNAc which lacks affinity for Gal8 had no effect. |
| TextSentencer_T11 | 1406-1829 | Sentence | denotes | Affinity chromatography of cell extracts on a Gal8-affinity column and binding experiments with plant lectins, Maakia Amurensis and Sambucus Nigra, revealed that alpha(3)beta(1), alpha(5)beta(1), and alpha(v)beta(1) integrins are major counterreceptors of Gal8 in TM cells and that TM cell beta(1) integrins carry predominantly alpha2-3-sialylated glycans, which are high-affinity ligands for Gal8 but not for Gal1 or Gal3. |
| TextSentencer_T12 | 1830-1999 | Sentence | denotes | These data lead us to propose that Gal8 modulates TM cell adhesion and spreading, at least in part, by interacting with alpha2-3-sialylated glycans on beta(1) integrins. |
| T1 | 0-106 | Sentence | denotes | The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. |
| T2 | 107-275 | Sentence | denotes | Primary open angle glaucoma (POAG) is a major blindness-causing disease, characterized by elevated intraocular pressure due to an insufficient outflow of aqueous humor. |
| T3 | 276-379 | Sentence | denotes | The trabecular meshwork (TM) lining the aqueous outflow pathway modulates the aqueous outflow facility. |
| T4 | 380-549 | Sentence | denotes | TM cell adhesion, cell-matrix interactions, and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. |
| T5 | 550-756 | Sentence | denotes | In a recent study, we demonstrated that galectin-8 (Gal8) modulates the adhesion and cytoskeletal arrangement of TM cells and that it does so through binding to beta(1) integrins and inducing Rho signaling. |
| T6 | 757-879 | Sentence | denotes | The current study is aimed at the characterization of the mechanism by which Gal8 mediates TM cell adhesion and spreading. |
| T7 | 880-1020 | Sentence | denotes | We demonstrate here that TM cells adhere to and spread on Gal8-coated wells but not on galectin-1 (Gal1)- or galectin-3 (Gal3)-coated wells. |
| T8 | 1021-1158 | Sentence | denotes | The adhesion of TM cells to Gal8-coated wells was abolished by a competing sugar, beta-lactose, but not by a noncompeting sugar, sucrose. |
| T9 | 1159-1317 | Sentence | denotes | Also, a trisaccharide, NeuAcalpha2-3Galbeta1-4GlcNAc, which binds specifically to the N-CRD of Gal8, inhibited the spreading of TM cells to Gal8-coated wells. |
| T10 | 1318-1405 | Sentence | denotes | In contrast, NeuAcalpha2-6Galbeta1-4GlcNAc which lacks affinity for Gal8 had no effect. |
| T11 | 1406-1829 | Sentence | denotes | Affinity chromatography of cell extracts on a Gal8-affinity column and binding experiments with plant lectins, Maakia Amurensis and Sambucus Nigra, revealed that alpha(3)beta(1), alpha(5)beta(1), and alpha(v)beta(1) integrins are major counterreceptors of Gal8 in TM cells and that TM cell beta(1) integrins carry predominantly alpha2-3-sialylated glycans, which are high-affinity ligands for Gal8 but not for Gal1 or Gal3. |
| T12 | 1830-1999 | Sentence | denotes | These data lead us to propose that Gal8 modulates TM cell adhesion and spreading, at least in part, by interacting with alpha2-3-sialylated glycans on beta(1) integrins. |
| T1 | 0-106 | Sentence | denotes | The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. |
| T2 | 107-275 | Sentence | denotes | Primary open angle glaucoma (POAG) is a major blindness-causing disease, characterized by elevated intraocular pressure due to an insufficient outflow of aqueous humor. |
| T3 | 276-379 | Sentence | denotes | The trabecular meshwork (TM) lining the aqueous outflow pathway modulates the aqueous outflow facility. |
| T4 | 380-549 | Sentence | denotes | TM cell adhesion, cell-matrix interactions, and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. |
| T5 | 550-756 | Sentence | denotes | In a recent study, we demonstrated that galectin-8 (Gal8) modulates the adhesion and cytoskeletal arrangement of TM cells and that it does so through binding to beta(1) integrins and inducing Rho signaling. |
| T6 | 757-879 | Sentence | denotes | The current study is aimed at the characterization of the mechanism by which Gal8 mediates TM cell adhesion and spreading. |
| T7 | 880-1020 | Sentence | denotes | We demonstrate here that TM cells adhere to and spread on Gal8-coated wells but not on galectin-1 (Gal1)- or galectin-3 (Gal3)-coated wells. |
| T8 | 1021-1158 | Sentence | denotes | The adhesion of TM cells to Gal8-coated wells was abolished by a competing sugar, beta-lactose, but not by a noncompeting sugar, sucrose. |
| T9 | 1159-1317 | Sentence | denotes | Also, a trisaccharide, NeuAcalpha2-3Galbeta1-4GlcNAc, which binds specifically to the N-CRD of Gal8, inhibited the spreading of TM cells to Gal8-coated wells. |
| T10 | 1318-1405 | Sentence | denotes | In contrast, NeuAcalpha2-6Galbeta1-4GlcNAc which lacks affinity for Gal8 had no effect. |
| T11 | 1406-1829 | Sentence | denotes | Affinity chromatography of cell extracts on a Gal8-affinity column and binding experiments with plant lectins, Maakia Amurensis and Sambucus Nigra, revealed that alpha(3)beta(1), alpha(5)beta(1), and alpha(v)beta(1) integrins are major counterreceptors of Gal8 in TM cells and that TM cell beta(1) integrins carry predominantly alpha2-3-sialylated glycans, which are high-affinity ligands for Gal8 but not for Gal1 or Gal3. |
| T12 | 1830-1999 | Sentence | denotes | These data lead us to propose that Gal8 modulates TM cell adhesion and spreading, at least in part, by interacting with alpha2-3-sialylated glycans on beta(1) integrins. |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 107-125 | http://purl.bioontology.org/ontology/ICD10/H40.1 | denotes | Primary open angle |
| T2 | 107-134 | http://purl.bioontology.org/ontology/ICD10/H40.1 | denotes | Primary open angle glaucoma |
| T3 | 115-134 | http://purl.bioontology.org/ontology/ICD10/H40.1 | denotes | open angle glaucoma |
| T4 | 126-134 | http://purl.bioontology.org/ontology/ICD10/H40.9 | denotes | glaucoma |
| T5 | 126-134 | http://purl.bioontology.org/ontology/ICD10/H40 | denotes | glaucoma |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 12-20 | FMAID:165244 | denotes | integrin |
| _T2 | 12-20 | FMAID:67222 | denotes | integrin |
| _T3 | 58-68 | FMAID:85273 | denotes | trabecular |
| _T4 | 58-68 | FMAID:199626 | denotes | trabecular |
| _T5 | 261-274 | FMAID:158798 | denotes | aqueous humor |
| _T6 | 280-290 | FMAID:199626 | denotes | trabecular |
| _T7 | 280-290 | FMAID:85273 | denotes | trabecular |
| _T8 | 305-311 | FMAID:146302 | denotes | lining |
| _T9 | 305-311 | FMAID:50595 | denotes | lining |
| _T10 | 471-476 | FMAID:169002 | denotes | cells |
| _T11 | 471-476 | FMAID:68646 | denotes | cells |
| _T12 | 635-647 | FMAID:162297 | denotes | cytoskeletal |
| _T13 | 635-647 | FMAID:63834 | denotes | cytoskeletal |
| _T14 | 666-671 | FMAID:169002 | denotes | cells |
| _T15 | 666-671 | FMAID:68646 | denotes | cells |
| _T16 | 719-728 | FMAID:165244 | denotes | integrins |
| _T17 | 719-728 | FMAID:67222 | denotes | integrins |
| _T18 | 908-913 | FMAID:169002 | denotes | cells |
| _T19 | 908-913 | FMAID:68646 | denotes | cells |
| _T20 | 1040-1045 | FMAID:68646 | denotes | cells |
| _T21 | 1040-1045 | FMAID:169002 | denotes | cells |
| _T22 | 1096-1101 | FMAID:196724 | denotes | sugar |
| _T23 | 1143-1148 | FMAID:196724 | denotes | sugar |
| _T24 | 1290-1295 | FMAID:68646 | denotes | cells |
| _T25 | 1290-1295 | FMAID:169002 | denotes | cells |
| _T26 | 1466-1472 | FMAID:183891 | denotes | column |
| _T27 | 1466-1472 | FMAID:76737 | denotes | column |
| _T28 | 1502-1507 | FMAID:214748 | denotes | plant |
| _T29 | 1622-1631 | FMAID:67222 | denotes | integrins |
| _T30 | 1622-1631 | FMAID:165244 | denotes | integrins |
| _T31 | 1673-1678 | FMAID:169002 | denotes | cells |
| _T32 | 1673-1678 | FMAID:68646 | denotes | cells |
| _T33 | 1704-1713 | FMAID:165244 | denotes | integrins |
| _T34 | 1704-1713 | FMAID:67222 | denotes | integrins |
| _T35 | 1989-1998 | FMAID:165244 | denotes | integrins |
| _T36 | 1989-1998 | FMAID:67222 | denotes | integrins |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-48 | http://www.uniprot.org/uniprot/Q9H585 | denotes | galectin-8 |
| T2 | 590-600 | http://www.uniprot.org/uniprot/Q9H585 | denotes | galectin-8 |
| T3 | 301-303 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T4 | 380-382 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T5 | 468-470 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T6 | 663-665 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T7 | 848-850 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T8 | 905-907 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T9 | 1037-1039 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T10 | 1287-1289 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T11 | 1670-1672 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T12 | 1688-1690 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T13 | 1880-1882 | http://www.uniprot.org/uniprot/P07204 | denotes | TM |
| T14 | 301-303 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T15 | 380-382 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T16 | 468-470 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T17 | 663-665 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T18 | 848-850 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T19 | 905-907 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T20 | 1037-1039 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T21 | 1287-1289 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T22 | 1670-1672 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T23 | 1688-1690 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T24 | 1880-1882 | http://www.uniprot.org/uniprot/Q14264 | denotes | TM |
| T25 | 301-303 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T26 | 380-382 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T27 | 468-470 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T28 | 663-665 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T29 | 848-850 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T30 | 905-907 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T31 | 1037-1039 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T32 | 1287-1289 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T33 | 1670-1672 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T34 | 1688-1690 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T35 | 1880-1882 | http://www.uniprot.org/uniprot/P60507 | denotes | TM |
| T36 | 301-303 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T37 | 380-382 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T38 | 468-470 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T39 | 663-665 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T40 | 848-850 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T41 | 905-907 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T42 | 1037-1039 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T43 | 1287-1289 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T44 | 1670-1672 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T45 | 1688-1690 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T46 | 1880-1882 | http://www.uniprot.org/uniprot/P60608 | denotes | TM |
| T47 | 301-303 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T48 | 380-382 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T49 | 468-470 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T50 | 663-665 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T51 | 848-850 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T52 | 905-907 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T53 | 1037-1039 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T54 | 1287-1289 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T55 | 1670-1672 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T56 | 1688-1690 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T57 | 1880-1882 | http://www.uniprot.org/uniprot/P60508 | denotes | TM |
| T58 | 301-303 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T59 | 380-382 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T60 | 468-470 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T61 | 663-665 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T62 | 848-850 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T63 | 905-907 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T64 | 1037-1039 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T65 | 1287-1289 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T66 | 1670-1672 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T67 | 1688-1690 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T68 | 1880-1882 | http://www.uniprot.org/uniprot/Q902F9 | denotes | TM |
| T69 | 301-303 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T70 | 380-382 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T71 | 468-470 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T72 | 663-665 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T73 | 848-850 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T74 | 905-907 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T75 | 1037-1039 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T76 | 1287-1289 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T77 | 1670-1672 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T78 | 1688-1690 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T79 | 1880-1882 | http://www.uniprot.org/uniprot/Q9NX77 | denotes | TM |
| T80 | 301-303 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T81 | 380-382 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T82 | 468-470 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T83 | 663-665 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T84 | 848-850 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T85 | 905-907 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T86 | 1037-1039 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T87 | 1287-1289 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T88 | 1670-1672 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T89 | 1688-1690 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T90 | 1880-1882 | http://www.uniprot.org/uniprot/O42043 | denotes | TM |
| T91 | 301-303 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T92 | 380-382 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T93 | 468-470 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T94 | 663-665 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T95 | 848-850 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T96 | 905-907 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T97 | 1037-1039 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T98 | 1287-1289 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T99 | 1670-1672 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T100 | 1688-1690 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T101 | 1880-1882 | http://www.uniprot.org/uniprot/O71037 | denotes | TM |
| T102 | 301-303 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T103 | 380-382 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T104 | 468-470 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T105 | 663-665 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T106 | 848-850 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T107 | 905-907 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T108 | 1037-1039 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T109 | 1287-1289 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T110 | 1670-1672 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T111 | 1688-1690 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T112 | 1880-1882 | http://www.uniprot.org/uniprot/P61565 | denotes | TM |
| T113 | 301-303 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T114 | 380-382 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T115 | 468-470 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T116 | 663-665 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T117 | 848-850 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T118 | 905-907 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T119 | 1037-1039 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T120 | 1287-1289 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T121 | 1670-1672 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T122 | 1688-1690 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T123 | 1880-1882 | http://www.uniprot.org/uniprot/P61566 | denotes | TM |
| T124 | 301-303 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T125 | 380-382 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T126 | 468-470 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T127 | 663-665 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T128 | 848-850 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T129 | 905-907 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T130 | 1037-1039 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T131 | 1287-1289 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T132 | 1670-1672 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T133 | 1688-1690 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T134 | 1880-1882 | http://www.uniprot.org/uniprot/P61570 | denotes | TM |
| T135 | 301-303 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T136 | 380-382 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T137 | 468-470 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T138 | 663-665 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T139 | 848-850 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T140 | 905-907 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T141 | 1037-1039 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T142 | 1287-1289 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T143 | 1670-1672 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T144 | 1688-1690 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T145 | 1880-1882 | http://www.uniprot.org/uniprot/Q69384 | denotes | TM |
| T146 | 301-303 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T147 | 380-382 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T148 | 468-470 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T149 | 663-665 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T150 | 848-850 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T151 | 905-907 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T152 | 1037-1039 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T153 | 1287-1289 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T154 | 1670-1672 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T155 | 1688-1690 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T156 | 1880-1882 | http://www.uniprot.org/uniprot/P61567 | denotes | TM |
| T157 | 301-303 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T158 | 380-382 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T159 | 468-470 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T160 | 663-665 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T161 | 848-850 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T162 | 905-907 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T163 | 1037-1039 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T164 | 1287-1289 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T165 | 1670-1672 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T166 | 1688-1690 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T167 | 1880-1882 | http://www.uniprot.org/uniprot/Q902F8 | denotes | TM |
| T168 | 301-303 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T169 | 380-382 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T170 | 468-470 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T171 | 663-665 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T172 | 848-850 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T173 | 905-907 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T174 | 1037-1039 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T175 | 1287-1289 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T176 | 1670-1672 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T177 | 1688-1690 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T178 | 1880-1882 | http://www.uniprot.org/uniprot/Q9UKH3 | denotes | TM |
| T179 | 301-303 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T180 | 380-382 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T181 | 468-470 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T182 | 663-665 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T183 | 848-850 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T184 | 905-907 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T185 | 1037-1039 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T186 | 1287-1289 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T187 | 1670-1672 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T188 | 1688-1690 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T189 | 1880-1882 | http://www.uniprot.org/uniprot/P60509 | denotes | TM |
| T190 | 301-303 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T191 | 380-382 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T192 | 468-470 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T193 | 663-665 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T194 | 848-850 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T195 | 905-907 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T196 | 1037-1039 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T197 | 1287-1289 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T198 | 1670-1672 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T199 | 1688-1690 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T200 | 1880-1882 | http://www.uniprot.org/uniprot/P61550 | denotes | TM |
| T201 | 301-303 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T202 | 380-382 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T203 | 468-470 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T204 | 663-665 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T205 | 848-850 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T206 | 905-907 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T207 | 1037-1039 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T208 | 1287-1289 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T209 | 1670-1672 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T210 | 1688-1690 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T211 | 1880-1882 | http://www.uniprot.org/uniprot/Q9UQF0 | denotes | TM |
| T212 | 301-303 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T213 | 380-382 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T214 | 468-470 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T215 | 663-665 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T216 | 848-850 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T217 | 905-907 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T218 | 1037-1039 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T219 | 1287-1289 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T220 | 1670-1672 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T221 | 1688-1690 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T222 | 1880-1882 | http://www.uniprot.org/uniprot/Q9N2J8 | denotes | TM |
| T223 | 301-303 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T224 | 380-382 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T225 | 468-470 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T226 | 663-665 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T227 | 848-850 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T228 | 905-907 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T229 | 1037-1039 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T230 | 1287-1289 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T231 | 1670-1672 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T232 | 1688-1690 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T233 | 1880-1882 | http://www.uniprot.org/uniprot/Q9N2K0 | denotes | TM |
| T234 | 711-717 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T235 | 1576-1582 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T236 | 1593-1599 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T237 | 1614-1620 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T238 | 1696-1702 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T239 | 1981-1987 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta(1 |
| T240 | 711-728 | http://www.uniprot.org/uniprot/O95965 | denotes | beta(1) integrins |
| T241 | 1614-1631 | http://www.uniprot.org/uniprot/O95965 | denotes | beta(1) integrins |
| T242 | 1696-1713 | http://www.uniprot.org/uniprot/O95965 | denotes | beta(1) integrins |
| T243 | 1981-1998 | http://www.uniprot.org/uniprot/O95965 | denotes | beta(1) integrins |
| T244 | 711-728 | http://www.uniprot.org/uniprot/Q8WUM6 | denotes | beta(1) integrins |
| T245 | 1614-1631 | http://www.uniprot.org/uniprot/Q8WUM6 | denotes | beta(1) integrins |
| T246 | 1696-1713 | http://www.uniprot.org/uniprot/Q8WUM6 | denotes | beta(1) integrins |
| T247 | 1981-1998 | http://www.uniprot.org/uniprot/Q8WUM6 | denotes | beta(1) integrins |
| T248 | 967-977 | http://www.uniprot.org/uniprot/P09382 | denotes | galectin-1 |
| T249 | 989-999 | http://www.uniprot.org/uniprot/P17931 | denotes | galectin-3 |
| T250 | 1568-1580 | http://www.uniprot.org/uniprot/O14756 | denotes | alpha(3)beta |
| T251 | 1576-1590 | http://www.uniprot.org/uniprot/Q9UQI1 | denotes | beta(1), alpha |
| T252 | 1593-1611 | http://www.uniprot.org/uniprot/Q9UQI1 | denotes | beta(1), and alpha |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-48 | http://www.uniprot.org/uniprot/Q9JL15 | denotes | galectin-8 |
| T2 | 590-600 | http://www.uniprot.org/uniprot/Q9JL15 | denotes | galectin-8 |
| T3 | 301-303 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T4 | 380-382 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T5 | 468-470 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T6 | 663-665 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T7 | 848-850 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T8 | 905-907 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T9 | 1037-1039 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T10 | 1287-1289 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T11 | 1670-1672 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T12 | 1688-1690 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T13 | 1880-1882 | http://www.uniprot.org/uniprot/P15306 | denotes | TM |
| T14 | 301-303 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T15 | 380-382 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T16 | 468-470 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T17 | 663-665 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T18 | 848-850 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T19 | 905-907 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T20 | 1037-1039 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T21 | 1287-1289 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T22 | 1670-1672 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T23 | 1688-1690 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T24 | 1880-1882 | http://www.uniprot.org/uniprot/Q811M9 | denotes | TM |
| T25 | 451-454 | http://www.uniprot.org/uniprot/P15409 | denotes | Rho |
| T26 | 742-745 | http://www.uniprot.org/uniprot/P15409 | denotes | Rho |
| T27 | 711-728 | http://www.uniprot.org/uniprot/P09055 | denotes | beta(1) integrins |
| T28 | 1614-1631 | http://www.uniprot.org/uniprot/P09055 | denotes | beta(1) integrins |
| T29 | 1696-1713 | http://www.uniprot.org/uniprot/P09055 | denotes | beta(1) integrins |
| T30 | 1981-1998 | http://www.uniprot.org/uniprot/P09055 | denotes | beta(1) integrins |
| T31 | 967-977 | http://www.uniprot.org/uniprot/P16045 | denotes | galectin-1 |
| T32 | 989-999 | http://www.uniprot.org/uniprot/P16110 | denotes | galectin-3 |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 126-134 | http://purl.bioontology.org/ontology/NCBITAXON/443780 | denotes | glaucoma |
| T2 | 126-134 | http://purl.bioontology.org/ontology/NCBITAXON/5882 | denotes | glaucoma |
| T3 | 471-476 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T4 | 666-671 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T5 | 711-715 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T6 | 711-715 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T7 | 815-824 | http://purl.bioontology.org/ontology/NCBITAXON/127244 | denotes | mechanism |
| T8 | 908-913 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T9 | 1040-1045 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T10 | 1103-1107 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T11 | 1103-1107 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T12 | 1290-1295 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T13 | 1517-1533 | http://purl.bioontology.org/ontology/NCBITAXON/37501 | denotes | Maakia Amurensis |
| T14 | 1538-1552 | http://purl.bioontology.org/ontology/NCBITAXON/4202 | denotes | Sambucus Nigra |
| T15 | 1576-1580 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T16 | 1576-1580 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T17 | 1593-1597 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T18 | 1593-1597 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T19 | 1614-1618 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T20 | 1614-1618 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T21 | 1673-1678 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T22 | 1696-1700 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T23 | 1696-1700 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T24 | 1981-1985 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T25 | 1981-1985 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 21-34 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T2 | 78-91 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | cell adhesion |
| T3 | 383-396 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | cell adhesion |
| T4 | 851-864 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | cell adhesion |
| T5 | 388-402 | http://purl.obolibrary.org/obo/GO_0007155 | denotes | adhesion, cell |
| T6 | 388-409 | http://purl.obolibrary.org/obo/GO_0001954 | denotes | adhesion, cell-matrix |
| T7 | 388-409 | http://purl.obolibrary.org/obo/GO_0001953 | denotes | adhesion, cell-matrix |
| T8 | 388-409 | http://purl.obolibrary.org/obo/GO_0035759 | denotes | adhesion, cell-matrix |
| T9 | 388-409 | http://purl.obolibrary.org/obo/GO_0001952 | denotes | adhesion, cell-matrix |
| T10 | 388-409 | http://purl.obolibrary.org/obo/GO_0007160 | denotes | adhesion, cell-matrix |
| T11 | 455-464 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T12 | 746-755 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T13 | 519-529 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T14 | 1743-1753 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
| T15 | 1959-1969 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 700-707 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T2 | 1219-1224 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binds |
| T3 | 700-707 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T4 | 1219-1224 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binds |
| T5 | 700-707 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T6 | 1219-1224 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binds |
| T7 | 700-707 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T8 | 1219-1224 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binds |
| T9 | 1787-1794 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | ligands |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 78-82 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 383-387 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 398-402 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T4 | 851-855 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T5 | 1433-1437 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T6 | 1691-1695 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T7 | 471-476 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T8 | 666-671 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T9 | 908-913 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T10 | 1040-1045 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T11 | 1290-1295 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T12 | 1673-1678 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 58-68 | http://purl.obolibrary.org/obo/UBERON_0000440 | denotes | trabecular |
| T2 | 280-290 | http://purl.obolibrary.org/obo/UBERON_0000440 | denotes | trabecular |
Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| Lectin_T1 | 967-977 | https://acgg.asia/db/lfdb/LfDB0270 | denotes | galectin-1 |
| Lectin_T2 | 967-977 | https://acgg.asia/db/lfdb/LfDB0057 | denotes | galectin-1 |
| Lectin_T3 | 1001-1005 | https://acgg.asia/db/lfdb/LfDB0065 | denotes | Gal3 |
| Lectin_T4 | 1824-1828 | https://acgg.asia/db/lfdb/LfDB0065 | denotes | Gal3 |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 451-454 | "http://rdf.glycoinfo.org/glycan/G21328SM" | denotes | Rho |
| GlycanIUPAC_T2 | 742-745 | "http://rdf.glycoinfo.org/glycan/G21328SM" | denotes | Rho |
| GlycanIUPAC_T3 | 976-983 | "http://rdf.glycoinfo.org/glycan/G04340UO" | denotes | 1 (Gal1 |
| GlycanIUPAC_T4 | 976-983 | "http://rdf.glycoinfo.org/glycan/G79992SX" | denotes | 1 (Gal1 |
| GlycanIUPAC_T5 | 976-983 | "http://rdf.glycoinfo.org/glycan/G20773IW" | denotes | 1 (Gal1 |
| GlycanIUPAC_T6 | 976-983 | "http://rdf.glycoinfo.org/glycan/G61666PA" | denotes | 1 (Gal1 |
| GlycanIUPAC_T7 | 976-983 | "http://rdf.glycoinfo.org/glycan/G98350CS" | denotes | 1 (Gal1 |
| GlycanIUPAC_T8 | 976-983 | "http://rdf.glycoinfo.org/glycan/G26289JC" | denotes | 1 (Gal1 |
| GlycanIUPAC_T9 | 976-983 | "http://rdf.glycoinfo.org/glycan/G01753HF" | denotes | 1 (Gal1 |
| GlycanIUPAC_T10 | 976-983 | "http://rdf.glycoinfo.org/glycan/G25061NQ" | denotes | 1 (Gal1 |
| GlycanIUPAC_T11 | 976-983 | "http://rdf.glycoinfo.org/glycan/G91444NO" | denotes | 1 (Gal1 |
| GlycanIUPAC_T12 | 979-983 | "http://rdf.glycoinfo.org/glycan/G32871SU" | denotes | Gal1 |
| GlycanIUPAC_T13 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G32871SU" | denotes | Gal1 |
| GlycanIUPAC_T14 | 979-983 | "http://rdf.glycoinfo.org/glycan/G07087RJ" | denotes | Gal1 |
| GlycanIUPAC_T15 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G07087RJ" | denotes | Gal1 |
| GlycanIUPAC_T16 | 979-983 | "http://rdf.glycoinfo.org/glycan/G40843KY" | denotes | Gal1 |
| GlycanIUPAC_T17 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G40843KY" | denotes | Gal1 |
| GlycanIUPAC_T18 | 979-983 | "http://rdf.glycoinfo.org/glycan/G68158BT" | denotes | Gal1 |
| GlycanIUPAC_T19 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G68158BT" | denotes | Gal1 |
| GlycanIUPAC_T20 | 979-983 | "http://rdf.glycoinfo.org/glycan/G75623HL" | denotes | Gal1 |
| GlycanIUPAC_T21 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G75623HL" | denotes | Gal1 |
| GlycanIUPAC_T22 | 979-983 | "http://rdf.glycoinfo.org/glycan/G08908FU" | denotes | Gal1 |
| GlycanIUPAC_T23 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G08908FU" | denotes | Gal1 |
| GlycanIUPAC_T24 | 979-983 | "http://rdf.glycoinfo.org/glycan/G38028NH" | denotes | Gal1 |
| GlycanIUPAC_T25 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G38028NH" | denotes | Gal1 |
| GlycanIUPAC_T26 | 979-983 | "http://rdf.glycoinfo.org/glycan/G48426CT" | denotes | Gal1 |
| GlycanIUPAC_T27 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G48426CT" | denotes | Gal1 |
| GlycanIUPAC_T28 | 979-983 | "http://rdf.glycoinfo.org/glycan/G34526ZS" | denotes | Gal1 |
| GlycanIUPAC_T29 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G34526ZS" | denotes | Gal1 |
| GlycanIUPAC_T30 | 979-983 | "http://rdf.glycoinfo.org/glycan/G25681JY" | denotes | Gal1 |
| GlycanIUPAC_T31 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G25681JY" | denotes | Gal1 |
| GlycanIUPAC_T32 | 979-983 | "http://rdf.glycoinfo.org/glycan/G75236KD" | denotes | Gal1 |
| GlycanIUPAC_T33 | 1816-1820 | "http://rdf.glycoinfo.org/glycan/G75236KD" | denotes | Gal1 |
| GlycanIUPAC_T34 | 1096-1101 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T35 | 1143-1148 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T36 | 1096-1101 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T37 | 1143-1148 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T38 | 1096-1101 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T39 | 1143-1148 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 58-68 | http://purl.obolibrary.org/obo/UBERON_0000440 | denotes | trabecular |
| PD-UBERON-AE-B_T2 | 280-290 | http://purl.obolibrary.org/obo/UBERON_0000440 | denotes | trabecular |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 107-134 | Disease | denotes | Primary open angle glaucoma | http://purl.obolibrary.org/obo/MONDO_0007665 |
| T2 | 136-140 | Disease | denotes | POAG | http://purl.obolibrary.org/obo/MONDO_0007665 |
| T3 | 153-162 | Disease | denotes | blindness | http://purl.obolibrary.org/obo/MONDO_0001941 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1108-1115 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 107-134 | Phenotype | denotes | Primary open angle glaucoma | HP:0012108 |
| T2 | 136-140 | Phenotype | denotes | POAG | HP:0012108 |
| T3 | 153-162 | Phenotype | denotes | blindness | HP:0000618 |
| T4 | 197-226 | Phenotype | denotes | elevated intraocular pressure | HP:0007906 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1108-1115 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 107-134 | Phenotype | denotes | Primary open angle glaucoma | HP:0012108 |
| T2 | 136-140 | Phenotype | denotes | POAG | HP:0012108 |
| T3 | 153-162 | Phenotype | denotes | blindness | HP:0000618 |
| T4 | 197-226 | Phenotype | denotes | elevated intraocular pressure | HP:0007906 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 58-82 | Cell | denotes | trabecular meshwork cell | http://purl.obolibrary.org/obo/CL:0002367 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 115-134 | Disease | denotes | open angle glaucoma | MONDO:0005338 |
| T2 | 136-140 | Disease | denotes | POAG | MONDO:0005338 |
| T3 | 153-162 | Disease | denotes | blindness | MONDO:0001941 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 126-134 | Organism | denotes | glaucoma | 5882 |
| T2 | 1538-1552 | Organism | denotes | Sambucus Nigra | 4202 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 58-82 | Body_part | denotes | trabecular meshwork cell | http://purl.obolibrary.org/obo/CL_0002367 |
| T2 | 261-274 | Body_part | denotes | aqueous humor | http://purl.obolibrary.org/obo/UBERON_0001796 |
| T3 | 280-299 | Body_part | denotes | trabecular meshwork | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T4 | 301-303 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T5 | 380-382 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T6 | 468-470 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T7 | 663-665 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T8 | 848-850 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T9 | 905-907 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T10 | 1037-1039 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T11 | 1287-1289 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T12 | 1670-1672 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T13 | 1688-1690 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T14 | 1880-1882 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-106 | Sentence | denotes | The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. |
| T2 | 107-275 | Sentence | denotes | Primary open angle glaucoma (POAG) is a major blindness-causing disease, characterized by elevated intraocular pressure due to an insufficient outflow of aqueous humor. |
| T3 | 276-379 | Sentence | denotes | The trabecular meshwork (TM) lining the aqueous outflow pathway modulates the aqueous outflow facility. |
| T4 | 380-549 | Sentence | denotes | TM cell adhesion, cell-matrix interactions, and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. |
| T5 | 550-756 | Sentence | denotes | In a recent study, we demonstrated that galectin-8 (Gal8) modulates the adhesion and cytoskeletal arrangement of TM cells and that it does so through binding to beta(1) integrins and inducing Rho signaling. |
| T6 | 757-879 | Sentence | denotes | The current study is aimed at the characterization of the mechanism by which Gal8 mediates TM cell adhesion and spreading. |
| T7 | 880-1020 | Sentence | denotes | We demonstrate here that TM cells adhere to and spread on Gal8-coated wells but not on galectin-1 (Gal1)- or galectin-3 (Gal3)-coated wells. |
| T8 | 1021-1158 | Sentence | denotes | The adhesion of TM cells to Gal8-coated wells was abolished by a competing sugar, beta-lactose, but not by a noncompeting sugar, sucrose. |
| T9 | 1159-1317 | Sentence | denotes | Also, a trisaccharide, NeuAcalpha2-3Galbeta1-4GlcNAc, which binds specifically to the N-CRD of Gal8, inhibited the spreading of TM cells to Gal8-coated wells. |
| T10 | 1318-1405 | Sentence | denotes | In contrast, NeuAcalpha2-6Galbeta1-4GlcNAc which lacks affinity for Gal8 had no effect. |
| T11 | 1406-1829 | Sentence | denotes | Affinity chromatography of cell extracts on a Gal8-affinity column and binding experiments with plant lectins, Maakia Amurensis and Sambucus Nigra, revealed that alpha(3)beta(1), alpha(5)beta(1), and alpha(v)beta(1) integrins are major counterreceptors of Gal8 in TM cells and that TM cell beta(1) integrins carry predominantly alpha2-3-sialylated glycans, which are high-affinity ligands for Gal8 but not for Gal1 or Gal3. |
| T12 | 1830-1999 | Sentence | denotes | These data lead us to propose that Gal8 modulates TM cell adhesion and spreading, at least in part, by interacting with alpha2-3-sialylated glycans on beta(1) integrins. |
GlyCosmos15-Lectin-Jamboree
| Id | Subject | Object | Predicate | Lexical cue | glycosmos_id |
|---|---|---|---|---|---|
| T1 | 1001-1005 | Lectin | denotes | Gal3 | GL_004254 |
| T2 | 1824-1828 | Lectin | denotes | Gal3 | GL_004254 |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-106 | Sentence | denotes | The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. |
| T2 | 107-275 | Sentence | denotes | Primary open angle glaucoma (POAG) is a major blindness-causing disease, characterized by elevated intraocular pressure due to an insufficient outflow of aqueous humor. |
| T3 | 276-379 | Sentence | denotes | The trabecular meshwork (TM) lining the aqueous outflow pathway modulates the aqueous outflow facility. |
| T4 | 380-549 | Sentence | denotes | TM cell adhesion, cell-matrix interactions, and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. |
| T5 | 550-756 | Sentence | denotes | In a recent study, we demonstrated that galectin-8 (Gal8) modulates the adhesion and cytoskeletal arrangement of TM cells and that it does so through binding to beta(1) integrins and inducing Rho signaling. |
| T6 | 757-879 | Sentence | denotes | The current study is aimed at the characterization of the mechanism by which Gal8 mediates TM cell adhesion and spreading. |
| T7 | 880-1020 | Sentence | denotes | We demonstrate here that TM cells adhere to and spread on Gal8-coated wells but not on galectin-1 (Gal1)- or galectin-3 (Gal3)-coated wells. |
| T8 | 1021-1158 | Sentence | denotes | The adhesion of TM cells to Gal8-coated wells was abolished by a competing sugar, beta-lactose, but not by a noncompeting sugar, sucrose. |
| T9 | 1159-1317 | Sentence | denotes | Also, a trisaccharide, NeuAcalpha2-3Galbeta1-4GlcNAc, which binds specifically to the N-CRD of Gal8, inhibited the spreading of TM cells to Gal8-coated wells. |
| T10 | 1318-1405 | Sentence | denotes | In contrast, NeuAcalpha2-6Galbeta1-4GlcNAc which lacks affinity for Gal8 had no effect. |
| T11 | 1406-1829 | Sentence | denotes | Affinity chromatography of cell extracts on a Gal8-affinity column and binding experiments with plant lectins, Maakia Amurensis and Sambucus Nigra, revealed that alpha(3)beta(1), alpha(5)beta(1), and alpha(v)beta(1) integrins are major counterreceptors of Gal8 in TM cells and that TM cell beta(1) integrins carry predominantly alpha2-3-sialylated glycans, which are high-affinity ligands for Gal8 but not for Gal1 or Gal3. |
| T12 | 1830-1999 | Sentence | denotes | These data lead us to propose that Gal8 modulates TM cell adhesion and spreading, at least in part, by interacting with alpha2-3-sialylated glycans on beta(1) integrins. |
Lectin-Jamboree-small
| Id | Subject | Object | Predicate | Lexical cue | glycosmos_id |
|---|---|---|---|---|---|
| T1 | 1001-1005 | Lectin | denotes | Gal3 | GL_000491 |
| T2 | 1824-1828 | Lectin | denotes | Gal3 | GL_000491 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 261-274 | Body_part | denotes | aqueous humor | FMA:58819 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 126-134 | OrganismTaxon | denotes | glaucoma | 5882 |
| T2 | 1538-1552 | OrganismTaxon | denotes | Sambucus Nigra | 4202 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 58-82 | Body_part | denotes | trabecular meshwork cell | http://purl.obolibrary.org/obo/CL_0002367 |
| T2 | 261-274 | Body_part | denotes | aqueous humor | http://purl.obolibrary.org/obo/UBERON_0001796 |
| T3 | 280-299 | Body_part | denotes | trabecular meshwork | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T4 | 301-303 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T5 | 380-382 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T6 | 468-470 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T7 | 663-665 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T8 | 848-850 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T9 | 905-907 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T10 | 1037-1039 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T11 | 1287-1289 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T12 | 1670-1672 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T13 | 1688-1690 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
| T14 | 1880-1882 | Body_part | denotes | TM | http://purl.obolibrary.org/obo/UBERON_0005969 |
GlyCosmos15-Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 979-983 | GL_000469 | denotes | Gal1 |
| T2 | 1001-1005 | GL_000491 | denotes | Gal3 |
| T3 | 1816-1820 | GL_000469 | denotes | Gal1 |
| T4 | 1824-1828 | GL_000491 | denotes | Gal3 |
Lectin_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 979-983 | GL_000469 | denotes | Gal1 |
| T2 | 1001-1005 | GL_000491 | denotes | Gal3 |
| T3 | 1816-1820 | GL_000469 | denotes | Gal1 |
| T4 | 1824-1828 | GL_000491 | denotes | Gal3 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 58-82 | Cell | denotes | trabecular meshwork cell | http://purl.obolibrary.org/obo/CL:0002367 |