> top > docs > PubMed:18842962 > annotations

PubMed:18842962 JSONTXT

Annnotations TAB JSON ListView MergeView

PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 72-84 DiseaseOrPhenotypicFeature denotes tuberculosis 0018076
T2 170-182 DiseaseOrPhenotypicFeature denotes tuberculosis 0018076

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-102 Sentence denotes N-Terminal clustering of the O-glycosylation sites in the Mycobacterium tuberculosis lipoprotein SodC.
TextSentencer_T2 103-183 Sentence denotes SodC is one of two superoxide dismutases produced by Mycobacterium tuberculosis.
TextSentencer_T3 184-276 Sentence denotes This protein was previously shown to contribute to virulence and to act as a B-cell antigen.
TextSentencer_T4 277-421 Sentence denotes SodC is also a putative lipoprotein, and like other Sec-translocated mycobacterial proteins it was suggested to be modified with glycosyl units.
TextSentencer_T5 422-574 Sentence denotes To definitively define the glycosylation of SodC, we applied an approach that combined site-directed mutagenesis, lectin binding, and mass spectrometry.
TextSentencer_T6 575-688 Sentence denotes This resulted in identification of six O-glycosylated residues within a 13-amino-acid region near the N-terminus.
TextSentencer_T7 689-820 Sentence denotes Each residue was modified with one to three hexose units, and the most dominant SodC glycoform was modified with nine hexose units.
TextSentencer_T8 821-956 Sentence denotes In addition to O-glycosylation of threonine residues, this study provides the first evidence of serine O-glycosylation in mycobacteria.
TextSentencer_T9 957-1163 Sentence denotes When combined with bioinformatic analyses, the clustering of O-glycosylation appeared to occur in a region of SodC with a disordered structure and not in regions important to the enzymatic activity of SodC.
TextSentencer_T10 1164-1369 Sentence denotes The use of recombinant amino acid substitutions to alter glycosylation sites provided further evidence that glycosylation influences proteolytic processing and ultimately positioning of cell wall proteins.
T1 0-102 Sentence denotes N-Terminal clustering of the O-glycosylation sites in the Mycobacterium tuberculosis lipoprotein SodC.
T2 103-183 Sentence denotes SodC is one of two superoxide dismutases produced by Mycobacterium tuberculosis.
T3 184-276 Sentence denotes This protein was previously shown to contribute to virulence and to act as a B-cell antigen.
T4 277-421 Sentence denotes SodC is also a putative lipoprotein, and like other Sec-translocated mycobacterial proteins it was suggested to be modified with glycosyl units.
T5 422-574 Sentence denotes To definitively define the glycosylation of SodC, we applied an approach that combined site-directed mutagenesis, lectin binding, and mass spectrometry.
T6 575-688 Sentence denotes This resulted in identification of six O-glycosylated residues within a 13-amino-acid region near the N-terminus.
T7 689-820 Sentence denotes Each residue was modified with one to three hexose units, and the most dominant SodC glycoform was modified with nine hexose units.
T8 821-956 Sentence denotes In addition to O-glycosylation of threonine residues, this study provides the first evidence of serine O-glycosylation in mycobacteria.
T9 957-1163 Sentence denotes When combined with bioinformatic analyses, the clustering of O-glycosylation appeared to occur in a region of SodC with a disordered structure and not in regions important to the enzymatic activity of SodC.
T10 1164-1369 Sentence denotes The use of recombinant amino acid substitutions to alter glycosylation sites provided further evidence that glycosylation influences proteolytic processing and ultimately positioning of cell wall proteins.
T1 0-102 Sentence denotes N-Terminal clustering of the O-glycosylation sites in the Mycobacterium tuberculosis lipoprotein SodC.
T2 103-183 Sentence denotes SodC is one of two superoxide dismutases produced by Mycobacterium tuberculosis.
T3 184-276 Sentence denotes This protein was previously shown to contribute to virulence and to act as a B-cell antigen.
T4 277-421 Sentence denotes SodC is also a putative lipoprotein, and like other Sec-translocated mycobacterial proteins it was suggested to be modified with glycosyl units.
T5 422-574 Sentence denotes To definitively define the glycosylation of SodC, we applied an approach that combined site-directed mutagenesis, lectin binding, and mass spectrometry.
T6 575-688 Sentence denotes This resulted in identification of six O-glycosylated residues within a 13-amino-acid region near the N-terminus.
T7 689-820 Sentence denotes Each residue was modified with one to three hexose units, and the most dominant SodC glycoform was modified with nine hexose units.
T8 821-956 Sentence denotes In addition to O-glycosylation of threonine residues, this study provides the first evidence of serine O-glycosylation in mycobacteria.
T9 957-1163 Sentence denotes When combined with bioinformatic analyses, the clustering of O-glycosylation appeared to occur in a region of SodC with a disordered structure and not in regions important to the enzymatic activity of SodC.
T10 1164-1369 Sentence denotes The use of recombinant amino acid substitutions to alter glycosylation sites provided further evidence that glycosylation influences proteolytic processing and ultimately positioning of cell wall proteins.

ICD10

Id Subject Object Predicate Lexical cue
T1 72-84 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis
T2 170-182 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 85-96 FMAID:167415 denotes lipoprotein
_T2 85-96 FMAID:63169 denotes lipoprotein
_T3 189-196 FMAID:165447 denotes protein
_T4 189-196 FMAID:67257 denotes protein
_T5 301-312 FMAID:167415 denotes lipoprotein
_T6 301-312 FMAID:63169 denotes lipoprotein
_T7 360-368 FMAID:67257 denotes proteins
_T8 360-368 FMAID:165447 denotes proteins
_T9 650-660 FMAID:196728 denotes amino-acid
_T10 650-660 FMAID:82739 denotes amino-acid
_T11 855-864 FMAID:82765 denotes threonine
_T12 855-864 FMAID:196754 denotes threonine
_T13 917-923 FMAID:67710 denotes serine
_T14 917-923 FMAID:165609 denotes serine
_T15 917-923 FMAID:196753 denotes serine
_T16 917-923 FMAID:82764 denotes serine
_T17 1108-1118 FMAID:100929 denotes in regions
_T18 1187-1197 FMAID:196728 denotes amino acid
_T19 1187-1197 FMAID:82739 denotes amino acid
_T20 1360-1368 FMAID:165447 denotes proteins
_T21 1360-1368 FMAID:67257 denotes proteins

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 329-332 http://www.uniprot.org/uniprot/P17257 denotes Sec

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 58-71 http://purl.bioontology.org/ontology/NCBITAXON/33894 denotes Mycobacterium
T2 58-71 http://purl.bioontology.org/ontology/NCBITAXON/98668 denotes Mycobacterium
T3 58-71 http://purl.bioontology.org/ontology/NCBITAXON/370526 denotes Mycobacterium
T4 58-71 http://purl.bioontology.org/ontology/NCBITAXON/230710 denotes Mycobacterium
T5 58-71 http://purl.bioontology.org/ontology/NCBITAXON/318424 denotes Mycobacterium
T6 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1288388 denotes Mycobacterium
T7 58-71 http://purl.bioontology.org/ontology/NCBITAXON/39693 denotes Mycobacterium
T8 58-71 http://purl.bioontology.org/ontology/NCBITAXON/470074 denotes Mycobacterium
T9 58-71 http://purl.bioontology.org/ontology/NCBITAXON/368455 denotes Mycobacterium
T10 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1790 denotes Mycobacterium
T11 58-71 http://purl.bioontology.org/ontology/NCBITAXON/319706 denotes Mycobacterium
T12 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1791 denotes Mycobacterium
T13 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1795 denotes Mycobacterium
T14 58-71 http://purl.bioontology.org/ontology/NCBITAXON/56425 denotes Mycobacterium
T15 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1781 denotes Mycobacterium
T16 58-71 http://purl.bioontology.org/ontology/NCBITAXON/28045 denotes Mycobacterium
T17 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1794 denotes Mycobacterium
T18 58-71 http://purl.bioontology.org/ontology/NCBITAXON/1766 denotes Mycobacterium
T19 58-71 http://purl.bioontology.org/ontology/NCBITAXON/46351 denotes Mycobacterium
T20 58-71 http://purl.bioontology.org/ontology/NCBITAXON/912594 denotes Mycobacterium
T21 58-84 http://purl.bioontology.org/ontology/NCBITAXON/77643 denotes Mycobacterium tuberculosis
T22 72-84 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T23 156-169 http://purl.bioontology.org/ontology/NCBITAXON/319706 denotes Mycobacterium
T24 156-169 http://purl.bioontology.org/ontology/NCBITAXON/28045 denotes Mycobacterium
T25 156-169 http://purl.bioontology.org/ontology/NCBITAXON/912594 denotes Mycobacterium
T26 156-169 http://purl.bioontology.org/ontology/NCBITAXON/56425 denotes Mycobacterium
T27 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1781 denotes Mycobacterium
T28 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1791 denotes Mycobacterium
T29 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1795 denotes Mycobacterium
T30 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1790 denotes Mycobacterium
T31 156-169 http://purl.bioontology.org/ontology/NCBITAXON/46351 denotes Mycobacterium
T32 156-169 http://purl.bioontology.org/ontology/NCBITAXON/470074 denotes Mycobacterium
T33 156-169 http://purl.bioontology.org/ontology/NCBITAXON/368455 denotes Mycobacterium
T34 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1794 denotes Mycobacterium
T35 156-169 http://purl.bioontology.org/ontology/NCBITAXON/39693 denotes Mycobacterium
T36 156-169 http://purl.bioontology.org/ontology/NCBITAXON/230710 denotes Mycobacterium
T37 156-169 http://purl.bioontology.org/ontology/NCBITAXON/318424 denotes Mycobacterium
T38 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1766 denotes Mycobacterium
T39 156-169 http://purl.bioontology.org/ontology/NCBITAXON/370526 denotes Mycobacterium
T40 156-169 http://purl.bioontology.org/ontology/NCBITAXON/33894 denotes Mycobacterium
T41 156-169 http://purl.bioontology.org/ontology/NCBITAXON/98668 denotes Mycobacterium
T42 156-169 http://purl.bioontology.org/ontology/NCBITAXON/1288388 denotes Mycobacterium
T43 156-182 http://purl.bioontology.org/ontology/NCBITAXON/77643 denotes Mycobacterium tuberculosis
T44 170-182 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T45 346-359 http://purl.bioontology.org/ontology/NCBITAXON/36811 denotes mycobacterial
T46 943-955 http://purl.bioontology.org/ontology/NCBITAXON/33585 denotes mycobacteria

GO-BP

Id Subject Object Predicate Lexical cue
T1 31-44 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T2 449-462 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 838-851 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T4 926-939 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 1020-1033 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 1221-1234 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T7 406-414 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosyl
T8 616-628 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylated
T9 235-244 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T10 235-244 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence

GO-MF

Id Subject Object Predicate Lexical cue
T1 543-550 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 543-550 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T3 543-550 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T4 543-550 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-CC

Id Subject Object Predicate Lexical cue
T1 263-267 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 1350-1354 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1350-1359 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 72-84 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T2 170-182 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T6 575-688 Sentence denotes This resulted in identification of six O-glycosylated residues within a 13-amino-acid region near the N-terminus.
T7 689-820 Sentence denotes Each residue was modified with one to three hexose units, and the most dominant SodC glycoform was modified with nine hexose units.
T8 821-956 Sentence denotes In addition to O-glycosylation of threonine residues, this study provides the first evidence of serine O-glycosylation in mycobacteria.
T9 957-1163 Sentence denotes When combined with bioinformatic analyses, the clustering of O-glycosylation appeared to occur in a region of SodC with a disordered structure and not in regions important to the enzymatic activity of SodC.
T10 1164-1369 Sentence denotes The use of recombinant amino acid substitutions to alter glycosylation sites provided further evidence that glycosylation influences proteolytic processing and ultimately positioning of cell wall proteins.
T1 0-102 Sentence denotes N-Terminal clustering of the O-glycosylation sites in the Mycobacterium tuberculosis lipoprotein SodC.
T2 103-183 Sentence denotes SodC is one of two superoxide dismutases produced by Mycobacterium tuberculosis.
T3 184-276 Sentence denotes This protein was previously shown to contribute to virulence and to act as a B-cell antigen.
T4 277-421 Sentence denotes SodC is also a putative lipoprotein, and like other Sec-translocated mycobacterial proteins it was suggested to be modified with glycosyl units.
T5 422-574 Sentence denotes To definitively define the glycosylation of SodC, we applied an approach that combined site-directed mutagenesis, lectin binding, and mass spectrometry.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 58-84 OrganismTaxon denotes Mycobacterium tuberculosis 1773
T2 156-182 OrganismTaxon denotes Mycobacterium tuberculosis 1773

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 261-267 Body_part denotes B-cell http://purl.obolibrary.org/obo/CL_0000236
T2 1355-1359 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 259-267 Cell denotes a B-cell http://purl.obolibrary.org/obo/CL:4023097
T2 261-267 Cell denotes B-cell http://purl.obolibrary.org/obo/CL:0000236