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PubMed:18827816 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 63-77 DiseaseOrPhenotypicFeature denotes gastric cancer 0001056|0004950
T3 1529-1543 DiseaseOrPhenotypicFeature denotes gastric cancer 0001056|0004950

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-150 Sentence denotes Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis.
TextSentencer_T2 151-313 Sentence denotes Gene expression profiling is a valuable tool for identifying differentially expressed genes in studies of disease subtype and patient outcome for various cancers.
TextSentencer_T3 314-406 Sentence denotes However, it remains difficult to assign biological significance to the vast number of genes.
TextSentencer_T4 407-606 Sentence denotes There is an increasing awareness of gene expression profile as an important part of the contextual molecular network at play in complex biological processes such as cancer initiation and progression.
TextSentencer_T5 607-836 Sentence denotes This study analysed the transcriptional profiles commonly activated at different stages of gastric cancers using an integrated approach combining gene expression profiling of 222 human tissues and gene regulatory dynamic mapping.
TextSentencer_T6 837-1021 Sentence denotes We focused on an inferred core network with CDKN1A (p21(WAF1/CIP1)) as the hub, and extracted seven candidates for gastric carcinogenesis (MMP7, SPARC, SOD2, INHBA, IGFBP7, NEK6, LUM).
TextSentencer_T7 1022-1119 Sentence denotes They were classified into two groups based on the correlation between expression level and stage.
TextSentencer_T8 1120-1229 Sentence denotes The seven genes were commonly activated and their expression levels tended to increase as disease progressed.
TextSentencer_T9 1230-1382 Sentence denotes NEK6 and INHBA are particularly promising candidate genes overexpressed at the protein level, as confirmed by immunohistochemistry and western blotting.
TextSentencer_T10 1383-1491 Sentence denotes This integrated approach could help to identify candidate players in gastric carcinogenesis and progression.
TextSentencer_T11 1492-1564 Sentence denotes These genes are potential markers of gastric cancer regardless of stage.
T1 0-150 Sentence denotes Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis.
T2 151-313 Sentence denotes Gene expression profiling is a valuable tool for identifying differentially expressed genes in studies of disease subtype and patient outcome for various cancers.
T3 314-406 Sentence denotes However, it remains difficult to assign biological significance to the vast number of genes.
T4 407-606 Sentence denotes There is an increasing awareness of gene expression profile as an important part of the contextual molecular network at play in complex biological processes such as cancer initiation and progression.
T5 607-836 Sentence denotes This study analysed the transcriptional profiles commonly activated at different stages of gastric cancers using an integrated approach combining gene expression profiling of 222 human tissues and gene regulatory dynamic mapping.
T6 837-1021 Sentence denotes We focused on an inferred core network with CDKN1A (p21(WAF1/CIP1)) as the hub, and extracted seven candidates for gastric carcinogenesis (MMP7, SPARC, SOD2, INHBA, IGFBP7, NEK6, LUM).
T7 1022-1119 Sentence denotes They were classified into two groups based on the correlation between expression level and stage.
T8 1120-1229 Sentence denotes The seven genes were commonly activated and their expression levels tended to increase as disease progressed.
T9 1230-1382 Sentence denotes NEK6 and INHBA are particularly promising candidate genes overexpressed at the protein level, as confirmed by immunohistochemistry and western blotting.
T10 1383-1491 Sentence denotes This integrated approach could help to identify candidate players in gastric carcinogenesis and progression.
T11 1492-1564 Sentence denotes These genes are potential markers of gastric cancer regardless of stage.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 881-887 gene:1026 denotes CDKN1A
T1 960-974 disease:C0596263 denotes carcinogenesis
T2 881-887 gene:5063 denotes CDKN1A
T3 960-974 disease:C0596263 denotes carcinogenesis
T4 893-897 gene:1026 denotes WAF1
T5 960-974 disease:C0596263 denotes carcinogenesis
T6 898-902 gene:1026 denotes CIP1
T7 960-974 disease:C0596263 denotes carcinogenesis
T8 898-902 gene:56996 denotes CIP1
T9 960-974 disease:C0596263 denotes carcinogenesis
T10 976-980 gene:4316 denotes MMP7
T11 960-974 disease:C0596263 denotes carcinogenesis
R1 T0 T1 associated_with CDKN1A,carcinogenesis
R2 T2 T3 associated_with CDKN1A,carcinogenesis
R3 T4 T5 associated_with WAF1,carcinogenesis
R4 T6 T7 associated_with CIP1,carcinogenesis
R5 T8 T9 associated_with CIP1,carcinogenesis
R6 T10 T11 associated_with MMP7,carcinogenesis

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
18827816-5#61#65#gene1026 898-902 gene1026 denotes CIP1
18827816-5#61#65#gene56996 898-902 gene56996 denotes CIP1
18827816-5#44#50#gene1026 881-887 gene1026 denotes CDKN1A
18827816-5#56#60#gene1026 893-897 gene1026 denotes WAF1
18827816-5#139#143#gene4316 976-980 gene4316 denotes MMP7
18827816-5#123#137#diseaseC0596263 960-974 diseaseC0596263 denotes carcinogenesis
61#65#gene1026123#137#diseaseC0596263 18827816-5#61#65#gene1026 18827816-5#123#137#diseaseC0596263 associated_with CIP1,carcinogenesis
61#65#gene56996123#137#diseaseC0596263 18827816-5#61#65#gene56996 18827816-5#123#137#diseaseC0596263 associated_with CIP1,carcinogenesis
44#50#gene1026123#137#diseaseC0596263 18827816-5#44#50#gene1026 18827816-5#123#137#diseaseC0596263 associated_with CDKN1A,carcinogenesis
56#60#gene1026123#137#diseaseC0596263 18827816-5#56#60#gene1026 18827816-5#123#137#diseaseC0596263 associated_with WAF1,carcinogenesis
139#143#gene4316123#137#diseaseC0596263 18827816-5#139#143#gene4316 18827816-5#123#137#diseaseC0596263 associated_with MMP7,carcinogenesis

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T1368 898-902 gene:1026 denotes CIP1
T1369 960-974 disease:C0596263 denotes carcinogenesis
R1 T1368 T1369 associated_with CIP1,carcinogenesis
R2 T1368 T1369 associated_with CIP1,carcinogenesis

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 97-102 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale
PD-UBERON-AE-B_T2 792-799 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 792-799 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 97-102 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale