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PubMed:18815291 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-110 Sentence denotes Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation.
TextSentencer_T2 111-306 Sentence denotes In recent years, many compounds having potent antiviral activity in cell culture have been detected and some of these compounds are currently undergoing either preclinical or clinical evaluation.
TextSentencer_T3 307-433 Sentence denotes Among these antiviral substances, naturally occurring sulfated polysaccharides and those from synthetic origin are noteworthy.
TextSentencer_T4 434-659 Sentence denotes Recently, several controversies over the molecular structures of sulfated polysaccharides, viral glycoproteins, and cell-surface receptors have been resolved, and many aspects of their antiviral activity have been elucidated.
TextSentencer_T5 660-854 Sentence denotes It has become clear that the antiviral properties of sulfated polysaccharides are not only a simple function of their charge density and chain length but also their detailed structural features.
TextSentencer_T6 855-1063 Sentence denotes The in vivo efficacy of these compounds mostly corresponds to their ability to inhibit the attachment of the virion to the host cell surface although in some cases virucidal activity plays an additional role.
TextSentencer_T7 1064-1277 Sentence denotes This review summarizes experimental evidence indicating that sulfated polysaccharides might become increasingly important in drug development for the prevention of sexually transmitted diseases in the near future.
T1 0-110 Sentence denotes Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation.
T2 111-306 Sentence denotes In recent years, many compounds having potent antiviral activity in cell culture have been detected and some of these compounds are currently undergoing either preclinical or clinical evaluation.
T3 307-433 Sentence denotes Among these antiviral substances, naturally occurring sulfated polysaccharides and those from synthetic origin are noteworthy.
T4 434-659 Sentence denotes Recently, several controversies over the molecular structures of sulfated polysaccharides, viral glycoproteins, and cell-surface receptors have been resolved, and many aspects of their antiviral activity have been elucidated.
T5 660-854 Sentence denotes It has become clear that the antiviral properties of sulfated polysaccharides are not only a simple function of their charge density and chain length but also their detailed structural features.
T6 855-1063 Sentence denotes The in vivo efficacy of these compounds mostly corresponds to their ability to inhibit the attachment of the virion to the host cell surface although in some cases virucidal activity plays an additional role.
T7 1064-1277 Sentence denotes This review summarizes experimental evidence indicating that sulfated polysaccharides might become increasingly important in drug development for the prevention of sexually transmitted diseases in the near future.
T1 0-110 Sentence denotes Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation.
T2 111-306 Sentence denotes In recent years, many compounds having potent antiviral activity in cell culture have been detected and some of these compounds are currently undergoing either preclinical or clinical evaluation.
T3 307-433 Sentence denotes Among these antiviral substances, naturally occurring sulfated polysaccharides and those from synthetic origin are noteworthy.
T4 434-659 Sentence denotes Recently, several controversies over the molecular structures of sulfated polysaccharides, viral glycoproteins, and cell-surface receptors have been resolved, and many aspects of their antiviral activity have been elucidated.
T5 660-854 Sentence denotes It has become clear that the antiviral properties of sulfated polysaccharides are not only a simple function of their charge density and chain length but also their detailed structural features.
T6 855-1063 Sentence denotes The in vivo efficacy of these compounds mostly corresponds to their ability to inhibit the attachment of the virion to the host cell surface although in some cases virucidal activity plays an additional role.
T7 1064-1277 Sentence denotes This review summarizes experimental evidence indicating that sulfated polysaccharides might become increasingly important in drug development for the prevention of sexually transmitted diseases in the near future.

ICD10

Id Subject Object Predicate Lexical cue
T1 1228-1257 http://purl.bioontology.org/ontology/ICD10/A64 denotes sexually transmitted diseases

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 37-52 FMAID:196735 denotes polysaccharides
_T2 37-52 FMAID:196779 denotes polysaccharides
_T3 37-52 FMAID:82746 denotes polysaccharides
_T4 37-52 FMAID:82785 denotes polysaccharides
_T5 133-142 FMAID:165656 denotes compounds
_T6 133-142 FMAID:67745 denotes compounds
_T7 176-183 FMAID:84785 denotes in cell
_T8 176-183 FMAID:199054 denotes in cell
_T9 229-238 FMAID:67745 denotes compounds
_T10 229-238 FMAID:165656 denotes compounds
_T11 370-385 FMAID:196735 denotes polysaccharides
_T12 370-385 FMAID:82785 denotes polysaccharides
_T13 370-385 FMAID:82746 denotes polysaccharides
_T14 370-385 FMAID:196779 denotes polysaccharides
_T15 508-523 FMAID:82785 denotes polysaccharides
_T16 508-523 FMAID:82746 denotes polysaccharides
_T17 508-523 FMAID:196779 denotes polysaccharides
_T18 508-523 FMAID:196735 denotes polysaccharides
_T19 531-544 FMAID:167256 denotes glycoproteins
_T20 531-544 FMAID:62925 denotes glycoproteins
_T21 550-562 FMAID:200942 denotes cell-surface
_T22 550-562 FMAID:212684 denotes cell-surface
_T23 555-562 FMAID:50594 denotes surface
_T24 555-562 FMAID:146300 denotes surface
_T25 722-737 FMAID:196735 denotes polysaccharides
_T26 722-737 FMAID:196779 denotes polysaccharides
_T27 722-737 FMAID:82785 denotes polysaccharides
_T28 722-737 FMAID:82746 denotes polysaccharides
_T29 885-894 FMAID:165656 denotes compounds
_T30 885-894 FMAID:67745 denotes compounds
_T31 983-995 FMAID:212684 denotes cell surface
_T32 983-995 FMAID:200942 denotes cell surface
_T33 988-995 FMAID:146300 denotes surface
_T34 988-995 FMAID:50594 denotes surface
_T35 1134-1149 FMAID:196779 denotes polysaccharides
_T36 1134-1149 FMAID:82785 denotes polysaccharides
_T37 1134-1149 FMAID:82746 denotes polysaccharides
_T38 1134-1149 FMAID:196735 denotes polysaccharides

uniprot-human

Id Subject Object Predicate Lexical cue
T1 550-572 http://www.uniprot.org/uniprot/Q9UKJ1 denotes cell-surface receptors
T2 550-572 http://www.uniprot.org/uniprot/Q9UKJ0 denotes cell-surface receptors

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 128-132 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes many
T2 563-572 http://purl.bioontology.org/ontology/STY/T192 denotes receptors
T3 597-601 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes many

GO-BP

Id Subject Object Predicate Lexical cue
T1 28-36 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T2 361-369 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T3 499-507 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T4 713-721 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T5 1125-1133 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T6 167-183 http://purl.obolibrary.org/obo/GO_0001775 denotes activity in cell
T7 1194-1205 http://purl.obolibrary.org/obo/GO_0032502 denotes development

GO-CC

Id Subject Object Predicate Lexical cue
T1 179-183 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 550-554 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 983-987 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 525-544 http://purl.obolibrary.org/obo/GO_0019031 denotes viral glycoproteins
T5 550-562 http://purl.obolibrary.org/obo/GO_0009986 denotes cell-surface
T6 983-995 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T7 964-970 http://purl.obolibrary.org/obo/GO_0019012 denotes virion
T8 978-982 http://purl.obolibrary.org/obo/GO_0018995 denotes host
T9 978-987 http://purl.obolibrary.org/obo/GO_0043657 denotes host cell
T10 978-995 http://purl.obolibrary.org/obo/GO_0044228 denotes host cell surface

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1228-1257 Disease denotes sexually transmitted diseases http://purl.obolibrary.org/obo/MONDO_0021681