| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-87 |
Sentence |
denotes |
Effect of capsaicin on ligand binding activity of the hippocampal serotonin1A receptor. |
| TextSentencer_T2 |
88-296 |
Sentence |
denotes |
The serotonin(1A) receptor is an important member of the G-protein coupled receptor family, and is involved in the generation and modulation of a variety of cognitive, behavioral, and developmental functions. |
| TextSentencer_T3 |
297-495 |
Sentence |
denotes |
In order to examine the role of membrane material properties in ligand binding activity of the hippocampal serotonin(1A) receptor, we monitored the function of the receptor in presence of capsaicin. |
| TextSentencer_T4 |
496-580 |
Sentence |
denotes |
Capsaicin has been previously shown to increase the elasticity of membrane bilayers. |
| TextSentencer_T5 |
581-756 |
Sentence |
denotes |
Our results show that the ligand binding activity of the hippocampal serotonin(1A) receptor is reduced in the presence of capsaicin in a linear concentration-dependent manner. |
| TextSentencer_T6 |
757-867 |
Sentence |
denotes |
This is accompanied by no appreciable change in G-protein coupling of the receptor and overall membrane order. |
| TextSentencer_T7 |
868-1049 |
Sentence |
denotes |
We conclude that material properties of membrane bilayers could play an important role in the function of the serotonin(1A) receptor in particular, and membrane proteins in general. |
| T1 |
0-87 |
Sentence |
denotes |
Effect of capsaicin on ligand binding activity of the hippocampal serotonin1A receptor. |
| T2 |
88-296 |
Sentence |
denotes |
The serotonin(1A) receptor is an important member of the G-protein coupled receptor family, and is involved in the generation and modulation of a variety of cognitive, behavioral, and developmental functions. |
| T3 |
297-495 |
Sentence |
denotes |
In order to examine the role of membrane material properties in ligand binding activity of the hippocampal serotonin(1A) receptor, we monitored the function of the receptor in presence of capsaicin. |
| T4 |
496-580 |
Sentence |
denotes |
Capsaicin has been previously shown to increase the elasticity of membrane bilayers. |
| T5 |
581-756 |
Sentence |
denotes |
Our results show that the ligand binding activity of the hippocampal serotonin(1A) receptor is reduced in the presence of capsaicin in a linear concentration-dependent manner. |
| T6 |
757-867 |
Sentence |
denotes |
This is accompanied by no appreciable change in G-protein coupling of the receptor and overall membrane order. |
| T7 |
868-1049 |
Sentence |
denotes |
We conclude that material properties of membrane bilayers could play an important role in the function of the serotonin(1A) receptor in particular, and membrane proteins in general. |
