PubMed:18777136
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 20-31 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T2 | 322-334 | Glycan_Motif | denotes | sialic acids | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T3 | 508-519 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T4 | 666-678 | Glycan_Motif | denotes | sialic acids | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 20-31 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T2 | 322-334 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acids |
| T3 | 508-519 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T4 | 666-678 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acids |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-63 | Sentence | denotes | Multiple changes in sialic acid biology during human evolution. |
| TextSentencer_T2 | 64-201 | Sentence | denotes | Humans are genetically very similar to "great apes", (chimpanzees, bonobos, gorillas and orangutans), our closest evolutionary relatives. |
| TextSentencer_T3 | 202-391 | Sentence | denotes | We have discovered multiple genetic and biochemical differences between humans and these other hominids, in relation to sialic acids and in Siglecs (Sia-recognizing Ig superfamily lectins). |
| TextSentencer_T4 | 392-536 | Sentence | denotes | An inactivating mutation in the CMAH gene eliminated human expression of N-glycolylneuraminic acid (Neu5Gc) a major sialic acid in "great apes". |
| TextSentencer_T5 | 537-679 | Sentence | denotes | Additional human-specific changes have been found, affecting at least 10 of the <60 genes known to be involved in the biology of sialic acids. |
| TextSentencer_T6 | 680-805 | Sentence | denotes | There are potential implications for unique features of humans, as well as for human susceptibility or resistance to disease. |
| TextSentencer_T7 | 806-1033 | Sentence | denotes | Additionally, metabolic incorporation of Neu5Gc from animal-derived materials occurs into biotherapeutic molecules and cellular preparations--and into human tissues from dietary sources, particularly red meat and milk products. |
| TextSentencer_T8 | 1034-1242 | Sentence | denotes | As humans also have varying and sometime high levels of circulating anti-Neu5Gc antibodies, there are implications for biotechnology products, and for some human diseases associated with chronic inflammation. |
| T1 | 0-63 | Sentence | denotes | Multiple changes in sialic acid biology during human evolution. |
| T2 | 64-201 | Sentence | denotes | Humans are genetically very similar to "great apes", (chimpanzees, bonobos, gorillas and orangutans), our closest evolutionary relatives. |
| T3 | 202-391 | Sentence | denotes | We have discovered multiple genetic and biochemical differences between humans and these other hominids, in relation to sialic acids and in Siglecs (Sia-recognizing Ig superfamily lectins). |
| T4 | 392-536 | Sentence | denotes | An inactivating mutation in the CMAH gene eliminated human expression of N-glycolylneuraminic acid (Neu5Gc) a major sialic acid in "great apes". |
| T5 | 537-679 | Sentence | denotes | Additional human-specific changes have been found, affecting at least 10 of the <60 genes known to be involved in the biology of sialic acids. |
| T6 | 680-805 | Sentence | denotes | There are potential implications for unique features of humans, as well as for human susceptibility or resistance to disease. |
| T7 | 806-1033 | Sentence | denotes | Additionally, metabolic incorporation of Neu5Gc from animal-derived materials occurs into biotherapeutic molecules and cellular preparations--and into human tissues from dietary sources, particularly red meat and milk products. |
| T8 | 1034-1242 | Sentence | denotes | As humans also have varying and sometime high levels of circulating anti-Neu5Gc antibodies, there are implications for biotechnology products, and for some human diseases associated with chronic inflammation. |
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-63 | Sentence | denotes | Multiple changes in sialic acid biology during human evolution. |
| T2 | 64-201 | Sentence | denotes | Humans are genetically very similar to "great apes", (chimpanzees, bonobos, gorillas and orangutans), our closest evolutionary relatives. |
| T3 | 202-391 | Sentence | denotes | We have discovered multiple genetic and biochemical differences between humans and these other hominids, in relation to sialic acids and in Siglecs (Sia-recognizing Ig superfamily lectins). |
| T4 | 392-536 | Sentence | denotes | An inactivating mutation in the CMAH gene eliminated human expression of N-glycolylneuraminic acid (Neu5Gc) a major sialic acid in "great apes". |
| T5 | 537-679 | Sentence | denotes | Additional human-specific changes have been found, affecting at least 10 of the <60 genes known to be involved in the biology of sialic acids. |
| T6 | 680-805 | Sentence | denotes | There are potential implications for unique features of humans, as well as for human susceptibility or resistance to disease. |
| T7 | 806-1033 | Sentence | denotes | Additionally, metabolic incorporation of Neu5Gc from animal-derived materials occurs into biotherapeutic molecules and cellular preparations--and into human tissues from dietary sources, particularly red meat and milk products. |
| T8 | 1034-1242 | Sentence | denotes | As humans also have varying and sometime high levels of circulating anti-Neu5Gc antibodies, there are implications for biotechnology products, and for some human diseases associated with chronic inflammation. |
| T1 | 0-63 | Sentence | denotes | Multiple changes in sialic acid biology during human evolution. |
| T2 | 64-201 | Sentence | denotes | Humans are genetically very similar to "great apes", (chimpanzees, bonobos, gorillas and orangutans), our closest evolutionary relatives. |
| T3 | 202-391 | Sentence | denotes | We have discovered multiple genetic and biochemical differences between humans and these other hominids, in relation to sialic acids and in Siglecs (Sia-recognizing Ig superfamily lectins). |
| T4 | 392-536 | Sentence | denotes | An inactivating mutation in the CMAH gene eliminated human expression of N-glycolylneuraminic acid (Neu5Gc) a major sialic acid in "great apes". |
| T5 | 537-679 | Sentence | denotes | Additional human-specific changes have been found, affecting at least 10 of the <60 genes known to be involved in the biology of sialic acids. |
| T6 | 680-805 | Sentence | denotes | There are potential implications for unique features of humans, as well as for human susceptibility or resistance to disease. |
| T7 | 806-1033 | Sentence | denotes | Additionally, metabolic incorporation of Neu5Gc from animal-derived materials occurs into biotherapeutic molecules and cellular preparations--and into human tissues from dietary sources, particularly red meat and milk products. |
| T8 | 1034-1242 | Sentence | denotes | As humans also have varying and sometime high levels of circulating anti-Neu5Gc antibodies, there are implications for biotechnology products, and for some human diseases associated with chronic inflammation. |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1229-1241 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 47-52 | OrganismTaxon | denotes | human | 9606 |
| T2 | 153-163 | OrganismTaxon | denotes | orangutans | 9600|9601 |
| T4 | 445-450 | OrganismTaxon | denotes | human | 9606 |
| T5 | 548-553 | OrganismTaxon | denotes | human | 9606 |
| T6 | 759-764 | OrganismTaxon | denotes | human | 9606 |
| T7 | 957-962 | OrganismTaxon | denotes | human | 9606 |
| T8 | 1190-1195 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1019-1023 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |