PubMed:1854781
Annnotations
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 39-42 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 169-172 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T3 | 373-376 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T4 | 392-395 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T5 | 915-918 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T6 | 1170-1173 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T7 | 1340-1343 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 39-42 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 169-172 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T3 | 373-376 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T4 | 392-395 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T5 | 915-918 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T6 | 1170-1173 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T7 | 1340-1343 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 240-244 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 69-75 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T2 | 116-119 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/UBERON_0007379 |
| T3 | 304-310 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T4 | 338-344 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T5 | 399-405 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T6 | 602-608 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T7 | 722-728 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T8 | 766-771 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T9 | 817-822 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T10 | 827-833 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T11 | 959-965 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T12 | 1105-1113 | Body_part | denotes | red pulp | http://purl.obolibrary.org/obo/UBERON_0001250 |
| T13 | 1194-1200 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T14 | 1227-1232 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T15 | 1395-1400 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T16 | 1445-1451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T17 | 1572-1578 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T18 | 1659-1665 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 69-75 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T2 | 116-119 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/MAT_0000213 |
| T3 | 304-310 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T4 | 338-344 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T5 | 399-405 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T6 | 602-608 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T7 | 722-728 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T8 | 766-771 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T9 | 817-822 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T10 | 827-833 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T11 | 959-965 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T12 | 1194-1200 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T13 | 1227-1232 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T15 | 1395-1400 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T16 | 1445-1451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T17 | 1572-1578 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T18 | 1659-1665 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-76 | Sentence | denotes | Large liposomes containing ganglioside GM1 accumulate effectively in spleen. |
| T2 | 77-245 | Sentence | denotes | Large liposomes, with a composition of egg phosphatidylcholine, cholesterol and ganglioside GM1, prepared by an extrusion method, were injected intravenously into mice. |
| T3 | 246-377 | Sentence | denotes | After 24 h, up to 50% of injected dose was accumulated in spleen compared with about 15% in spleen for liposomes containing no GM1. |
| T4 | 378-460 | Sentence | denotes | The effect of GM1 on spleen accumulation of liposomes was liposome size dependent. |
| T5 | 461-597 | Sentence | denotes | Only relatively large liposomes (d greater than 300 nm) showed high accumulation; smaller liposomes were progressively less accumulated. |
| T6 | 598-680 | Sentence | denotes | The spleen accumulation increased with increasing injection dose of the liposomes. |
| T7 | 681-919 | Sentence | denotes | It was noted that the enhanced uptake by spleen was accompanied by a decrease in the liver uptake, but the total uptake of liposomes by liver and spleen was not dependent on the diameter of liposome or the presence of the ganglioside GM1. |
| T8 | 920-1114 | Sentence | denotes | Autoradiographs of fixed and sectioned spleen using 125I-labeled tyraminylinulin as a content marker for the liposomes, showed that liposomes localized at the reticular meshwork of the red pulp. |
| T9 | 1115-1233 | Sentence | denotes | These results suggest that larger liposomes containing GM1 are filtered by the spleen during the circulation in blood. |
| T10 | 1234-1323 | Sentence | denotes | The smaller ones with a mean diameter of less than 100 nm are not retained by the filter. |
| T11 | 1324-1468 | Sentence | denotes | The function of GM1 is to prevent liposomes from a rapid uptake by the liver so that liposomes may circulate through the spleen and be filtered. |
| T12 | 1469-1666 | Sentence | denotes | These results, together with the observation that the liposome-entrapped proteins were degraded by the spleen, suggest the potential use of these liposomes for specific drug delivery to the spleen. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 39-42 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 169-172 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T3 | 373-376 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T4 | 392-395 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T5 | 915-918 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T6 | 1170-1173 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T7 | 1340-1343 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 39-42 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 169-172 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T3 | 373-376 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T4 | 392-395 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T5 | 915-918 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T6 | 1170-1173 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T7 | 1340-1343 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 240-244 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 69-75 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T2 | 116-119 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/MAT_0000213 |
| T3 | 304-310 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T4 | 338-344 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T5 | 399-405 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T6 | 602-608 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T7 | 722-728 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T8 | 766-771 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T9 | 817-822 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T10 | 827-833 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T11 | 959-965 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T12 | 1194-1200 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T13 | 1227-1232 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T15 | 1395-1400 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T16 | 1445-1451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T17 | 1572-1578 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
| T18 | 1659-1665 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/MAT_0000085 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 69-75 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T2 | 116-119 | Body_part | denotes | egg | http://purl.obolibrary.org/obo/UBERON_0007379 |
| T3 | 304-310 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T4 | 338-344 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T5 | 399-405 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T6 | 602-608 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T7 | 722-728 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T8 | 766-771 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T9 | 817-822 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T10 | 827-833 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T11 | 959-965 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T12 | 1105-1113 | Body_part | denotes | red pulp | http://purl.obolibrary.org/obo/UBERON_0001250 |
| T13 | 1194-1200 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T14 | 1227-1232 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T15 | 1395-1400 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T16 | 1445-1451 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T17 | 1572-1578 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |
| T18 | 1659-1665 | Body_part | denotes | spleen | http://purl.obolibrary.org/obo/UBERON_0002106 |