PubMed:1851861
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 29-45 | DiseaseOrPhenotypicFeature | denotes | immunodeficiency | 0021094 |
| T2 | 100-102 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T3 | 187-189 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T4 | 235-238 | DiseaseOrPhenotypicFeature | denotes | can | 0012833 |
| T5 | 258-274 | DiseaseOrPhenotypicFeature | denotes | immunodeficiency | 0021094 |
| T6 | 580-582 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T7 | 629-631 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T8 | 822-824 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T9 | 1256-1258 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T10 | 1260-1269 | DiseaseOrPhenotypicFeature | denotes | infection | 0005550 |
| T11 | 1434-1436 | DiseaseOrPhenotypicFeature | denotes | GS | 0005773 |
| T12 | 1438-1447 | DiseaseOrPhenotypicFeature | denotes | infection | 0005550 |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 23-60 | DNA | denotes | human immunodeficiency virus promoter |
| T2 | 115-142 | cell_type | denotes | primary human T lymphocytes |
| T3 | 165-205 | DNA | denotes | transactivating HHV-6(GS) gene fragments |
| T4 | 252-295 | DNA | denotes | human immunodeficiency virus (HIV) promoter |
| T5 | 333-359 | cell_type | denotes | HIV-infected human T cells |
| T6 | 400-412 | DNA | denotes | HIV promoter |
| T7 | 481-508 | cell_type | denotes | primary human T lymphocytes |
| T8 | 611-623 | DNA | denotes | HIV promoter |
| T9 | 658-666 | DNA | denotes | promoter |
| T10 | 698-705 | cell_type | denotes | T cells |
| T11 | 738-750 | DNA | denotes | HIV promoter |
| T12 | 768-786 | cell_type | denotes | stimulated T cells |
| T13 | 816-843 | DNA | denotes | HHV-6(GS) genomic fragments |
| T14 | 863-875 | DNA | denotes | HIV promoter |
| T15 | 879-900 | cell_line | denotes | cotransfected T cells |
| T16 | 904-921 | DNA | denotes | 21.4-kb DNA clone |
| T17 | 923-929 | DNA | denotes | pZVB70 |
| T18 | 991-1004 | DNA | denotes | DNA fragments |
| T19 | 1006-1012 | DNA | denotes | pZVB10 |
| T20 | 1026-1032 | DNA | denotes | pZVH14 |
| T21 | 1087-1093 | DNA | denotes | pZVH14 |
| T22 | 1109-1131 | DNA | denotes | HIV promoter construct |
| T23 | 1161-1176 | DNA | denotes | NF kappa B site |
| T24 | 1192-1219 | DNA | denotes | mutated NF kappa B promoter |
| T25 | 1299-1305 | DNA | denotes | pZVB70 |
| T26 | 1309-1315 | DNA | denotes | pZVB10 |
| T27 | 1346-1362 | DNA | denotes | NF kappa B sites |
| T28 | 1370-1382 | DNA | denotes | HIV promoter |
| T29 | 1463-1475 | DNA | denotes | HIV promoter |
| T30 | 1488-1509 | cell_type | denotes | primary T lymphocytes |
| T31 | 1611-1635 | cell_type | denotes | coinfected human T cells |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 1851861-8#22#32#gene4790 | 1200-1210 | gene4790 | denotes | NF kappa B |
| 1851861-8#78#80#diseaseC0017097 | 1256-1258 | diseaseC0017097 | denotes | GS |
| 22#32#gene479078#80#diseaseC0017097 | 1851861-8#22#32#gene4790 | 1851861-8#78#80#diseaseC0017097 | associated_with | NF kappa B,GS |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-206 | Sentence | denotes | Transactivation of the human immunodeficiency virus promoter by human herpesvirus 6 (HHV-6) strains GS and Z-29 in primary human T lymphocytes and identification of transactivating HHV-6(GS) gene fragments. |
| S2 | 207-360 | Sentence | denotes | Human herpesvirus 6 (HHV-6) can activate the human immunodeficiency virus (HIV) promoter and accelerate cytopathic effects in HIV-infected human T cells. |
| S3 | 361-547 | Sentence | denotes | This study examines the regions of the HIV promoter required for HHV-6 transactivation in a heterogeneous population of primary human T lymphocytes with or without antigenic stimulation. |
| S4 | 548-624 | Sentence | denotes | Two different strains of HHV-6, GS and Z29, transactivated the HIV promoter. |
| S5 | 625-787 | Sentence | denotes | The GS strain transactivated the promoter in both stimulated and resting T cells, while the Z29 strain increased HIV promoter activity only in stimulated T cells. |
| S6 | 788-901 | Sentence | denotes | Three DNA clones containing HHV-6(GS) genomic fragments transactivated the HIV promoter in cotransfected T cells. |
| S7 | 902-1065 | Sentence | denotes | A 21.4-kb DNA clone, pZVB70, showed the highest transactivating ability, while two other DNA fragments, pZVB10 (6.2 kb) and pZVH14 (8.7 kb), showed lower activity. |
| S8 | 1066-1177 | Sentence | denotes | One of these clones, pZVH14, activated the HIV promoter construct containing a mutation in the NF kappa B site. |
| S9 | 1178-1316 | Sentence | denotes | However, this mutated NF kappa B promoter was not transactivated during HHV-6(GS) infection or after cotransfection with pZVB70 or pZVB10. |
| S10 | 1317-1448 | Sentence | denotes | These data indicate that the NF kappa B sites of the HIV promoter are essential for its transactivation during HHV-6(GS) infection. |
| S11 | 1449-1636 | Sentence | denotes | By increasing HIV promoter activity in primary T lymphocytes, HHV-6 may consequently increase HIV replication, leading to an increase in the cytopathic effect on coinfected human T cells. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 19-60 | NP | denotes | the human immunodeficiency virus promoter |
| C2 | 64-91 | NP | denotes | human herpesvirus 6 (HHV-6) |
| C3 | 100-102 | NP | denotes | GS |
| C4 | 107-111 | NP | denotes | Z-29 |
| C5 | 115-142 | NP | denotes | primary human T lymphocytes |
| C6 | 181-190 | NP | denotes | HHV-6(GS) |
| C7 | 207-234 | NP | denotes | Human herpesvirus 6 (HHV-6) |
| C8 | 248-295 | NP | denotes | the human immunodeficiency virus (HIV) promoter |
| C9 | 346-359 | NP | denotes | human T cells |
| C10 | 396-412 | NP | denotes | the HIV promoter |
| C11 | 426-431 | NP | denotes | HHV-6 |
| C12 | 481-508 | NP | denotes | primary human T lymphocytes |
| C13 | 573-578 | NP | denotes | HHV-6 |
| C14 | 580-582 | NP | denotes | GS |
| C15 | 587-590 | NP | denotes | Z29 |
| C16 | 607-623 | NP | denotes | the HIV promoter |
| C17 | 625-638 | NP | denotes | The GS strain |
| C18 | 654-666 | NP | denotes | the promoter |
| C19 | 713-727 | NP | denotes | the Z29 strain |
| C21 | 738-750 | NP | denotes | HIV promoter |
| C20 | 738-759 | NP | denotes | HIV promoter activity |
| C22 | 816-825 | NP | denotes | HHV-6(GS) |
| C23 | 859-875 | NP | denotes | the HIV promoter |
| C24 | 902-921 | NP | denotes | A 21.4-kb DNA clone |
| C25 | 923-929 | NP | denotes | pZVB70 |
| C26 | 991-1004 | NP | denotes | DNA fragments |
| C28 | 1006-1021 | NP | denotes | pZVB10 (6.2 kb) |
| C27 | 1006-1041 | NP | denotes | pZVB10 (6.2 kb) and pZVH14 (8.7 kb) |
| C29 | 1105-1121 | NP | denotes | the HIV promoter |
| C30 | 1157-1176 | NP | denotes | the NF kappa B site |
| C31 | 1250-1259 | NP | denotes | HHV-6(GS) |
| C32 | 1299-1305 | NP | denotes | pZVB70 |
| C33 | 1309-1315 | NP | denotes | pZVB10 |
| C34 | 1342-1362 | NP | denotes | the NF kappa B sites |
| C35 | 1366-1382 | NP | denotes | the HIV promoter |
| C36 | 1401-1404 | NP | denotes | its |
| C37 | 1428-1437 | NP | denotes | HHV-6(GS) |
| C39 | 1463-1475 | NP | denotes | HIV promoter |
| C38 | 1463-1484 | NP | denotes | HIV promoter activity |
| C40 | 1488-1509 | NP | denotes | primary T lymphocytes |
| C41 | 1511-1516 | NP | denotes | HHV-6 |
| R1 | C6 | C2 | coref-other | HHV-6(GS),human herpesvirus 6 (HHV-6) |
| R2 | C7 | C2 | coref-ident | Human herpesvirus 6 (HHV-6),human herpesvirus 6 (HHV-6) |
| R3 | C8 | C1 | coref-ident | the human immunodeficiency virus (HIV) promoter,the human immunodeficiency virus promoter |
| R4 | C9 | C5 | coref-other | human T cells,primary human T lymphocytes |
| R5 | C10 | C8 | coref-ident | the HIV promoter,the human immunodeficiency virus (HIV) promoter |
| R6 | C11 | C7 | coref-ident | HHV-6,Human herpesvirus 6 (HHV-6) |
| R7 | C12 | C5 | coref-ident | primary human T lymphocytes,primary human T lymphocytes |
| R8 | C13 | C11 | coref-ident | HHV-6,HHV-6 |
| R9 | C14 | C3 | coref-ident | GS,GS |
| R10 | C15 | C4 | coref-ident | Z29,Z-29 |
| R11 | C16 | C10 | coref-ident | the HIV promoter,the HIV promoter |
| R12 | C17 | C14 | coref-other | The GS strain,GS |
| R13 | C18 | C16 | coref-ident | the promoter,the HIV promoter |
| R14 | C19 | C15 | coref-other | the Z29 strain,Z29 |
| R15 | C21 | C18 | coref-ident | HIV promoter,the promoter |
| R16 | C22 | C6 | coref-ident | HHV-6(GS),HHV-6(GS) |
| R17 | C23 | C21 | coref-ident | the HIV promoter,HIV promoter |
| R18 | C24 | C25 | coref-appos | A 21.4-kb DNA clone,pZVB70 |
| R19 | C26 | C27 | coref-appos | DNA fragments,pZVB10 (6.2 kb) and pZVH14 (8.7 kb) |
| R20 | C29 | C23 | coref-ident | the HIV promoter,the HIV promoter |
| R21 | C31 | C22 | coref-ident | HHV-6(GS),HHV-6(GS) |
| R22 | C32 | C25 | coref-ident | pZVB70,pZVB70 |
| R23 | C33 | C28 | coref-ident | pZVB10,pZVB10 (6.2 kb) |
| R24 | C34 | C30 | coref-ident | the NF kappa B sites,the NF kappa B site |
| R25 | C35 | C29 | coref-ident | the HIV promoter,the HIV promoter |
| R26 | C36 | C35 | coref-pron | its,the HIV promoter |
| R27 | C37 | C31 | coref-ident | HHV-6(GS),HHV-6(GS) |
| R28 | C39 | C35 | coref-ident | HIV promoter,the HIV promoter |
| R29 | C38 | C20 | coref-ident | HIV promoter activity,HIV promoter activity |
| R30 | C40 | C12 | coref-ident | primary T lymphocytes,primary human T lymphocytes |
| R31 | C41 | C13 | coref-ident | HHV-6,HHV-6 |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 23-51 | virus | denotes | human immunodeficiency virus |
| T2 | 64-83 | virus | denotes | human herpesvirus 6 |
| T3 | 85-90 | virus | denotes | HHV-6 |
| T4 | 115-130 | cell_type | denotes | primary human T |
| T5 | 131-142 | cell_type | denotes | lymphocytes |
| T6 | 165-186 | virus | denotes | transactivating HHV-6 |
| T7 | 207-226 | virus | denotes | Human herpesvirus 6 |
| T8 | 228-233 | virus | denotes | HHV-6 |
| T9 | 252-280 | virus | denotes | human immunodeficiency virus |
| T10 | 333-359 | cell_type | denotes | HIV-infected human T cells |
| T11 | 400-412 | DNA_domain_or_region | denotes | HIV promoter |
| T12 | 426-431 | virus | denotes | HHV-6 |
| T13 | 481-508 | cell_type | denotes | primary human T lymphocytes |
| T14 | 525-546 | other_name | denotes | antigenic stimulation |
| T15 | 573-578 | virus | denotes | HHV-6 |
| T16 | 580-582 | virus | denotes | GS |
| T17 | 587-590 | virus | denotes | Z29 |
| T18 | 611-623 | DNA_domain_or_region | denotes | HIV promoter |
| T19 | 629-638 | virus | denotes | GS strain |
| T20 | 658-666 | DNA_domain_or_region | denotes | promoter |
| T21 | 698-705 | cell_type | denotes | T cells |
| T22 | 717-727 | virus | denotes | Z29 strain |
| T23 | 738-750 | DNA_domain_or_region | denotes | HIV promoter |
| T24 | 768-786 | cell_type | denotes | stimulated T cells |
| T25 | 816-843 | DNA_molecule | denotes | HHV-6(GS) genomic fragments |
| T26 | 863-875 | DNA_domain_or_region | denotes | HIV promoter |
| T27 | 879-900 | cell_line | denotes | cotransfected T cells |
| T28 | 904-921 | DNA_molecule | denotes | 21.4-kb DNA clone |
| T29 | 923-929 | DNA_molecule | denotes | pZVB70 |
| T30 | 950-973 | other_name | denotes | transactivating ability |
| T31 | 991-1004 | DNA_molecule | denotes | DNA fragments |
| T32 | 1006-1012 | DNA_molecule | denotes | pZVB10 |
| T33 | 1026-1032 | DNA_molecule | denotes | pZVH14 |
| T34 | 1087-1093 | DNA_molecule | denotes | pZVH14 |
| T35 | 1109-1121 | DNA_domain_or_region | denotes | HIV promoter |
| T36 | 1161-1176 | DNA_molecule | denotes | NF kappa B site |
| T37 | 1192-1219 | DNA_domain_or_region | denotes | mutated NF kappa B promoter |
| T38 | 1250-1259 | virus | denotes | HHV-6(GS) |
| T39 | 1299-1305 | DNA_molecule | denotes | pZVB70 |
| T40 | 1309-1315 | DNA_molecule | denotes | pZVB10 |
| T41 | 1346-1362 | DNA_domain_or_region | denotes | NF kappa B sites |
| T42 | 1370-1382 | DNA_domain_or_region | denotes | HIV promoter |
| T43 | 1405-1420 | other_name | denotes | transactivation |
| T44 | 1428-1437 | virus | denotes | HHV-6(GS) |
| T45 | 1463-1475 | DNA_domain_or_region | denotes | HIV promoter |
| T46 | 1488-1509 | cell_type | denotes | primary T lymphocytes |
| T47 | 1511-1516 | virus | denotes | HHV-6 |
| T48 | 1543-1558 | other_name | denotes | HIV replication |
| T49 | 1611-1635 | cell_type | denotes | coinfected human T cells |