PubMed:18509108
Annnotations
Glycan-Motif
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 88-91 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T2 | 88-91 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T3 | 92-95 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T4 | 92-95 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T5 | 122-125 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T6 | 122-125 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T7 | 351-354 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T8 | 351-354 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T9 | 413-416 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T10 | 413-416 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T11 | 485-508 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
T12 | 485-508 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
T13 | 510-516 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T14 | 555-561 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T15 | 577-586 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
T16 | 577-586 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
T17 | 616-622 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T18 | 1272-1275 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T19 | 1272-1275 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T20 | 1281-1284 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T21 | 1281-1284 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T22 | 1377-1380 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T23 | 1377-1380 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T24 | 1437-1440 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T25 | 1437-1440 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T26 | 1490-1493 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T27 | 1490-1493 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T28 | 1601-1604 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T29 | 1601-1604 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T30 | 1657-1660 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T31 | 1657-1660 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T32 | 1736-1747 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
T33 | 1755-1758 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T34 | 1755-1758 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T35 | 1790-1793 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T36 | 1790-1793 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T37 | 1896-1899 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T38 | 1896-1899 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T39 | 2005-2017 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acids |
T40 | 2057-2060 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T41 | 2057-2060 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T42 | 2142-2153 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 88-91 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T3 | 92-95 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
T5 | 122-125 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T7 | 351-354 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
T9 | 413-416 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T11 | 485-508 | Glycan_Motif | denotes | N-acetylneuraminic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G50850NI |
T13 | 510-516 | Glycan_Motif | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
T14 | 555-561 | Glycan_Motif | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
T15 | 577-586 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
T17 | 616-622 | Glycan_Motif | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
T18 | 1272-1275 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
T20 | 1281-1284 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T22 | 1377-1380 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
T24 | 1437-1440 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
T26 | 1490-1493 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T28 | 1601-1604 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T30 | 1657-1660 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T32 | 1736-1747 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
T33 | 1755-1758 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T35 | 1790-1793 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
T37 | 1896-1899 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T39 | 2005-2017 | Glycan_Motif | denotes | sialic acids | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
T40 | 2057-2060 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
T42 | 2142-2153 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
PMID_GLOBAL
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 678-680 | DiseaseOrPhenotypicFeature | denotes | MF | 0009691|0020481 |
T3 | 702-704 | DiseaseOrPhenotypicFeature | denotes | NM | 0008091|0011603|0018958 |
T6 | 743-745 | DiseaseOrPhenotypicFeature | denotes | AM | 0020320 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
TextSentencer_T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
TextSentencer_T3 | 761-766 | Sentence | denotes | 2002. |
TextSentencer_T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
TextSentencer_T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
TextSentencer_T6 | 953-965 | Sentence | denotes | J Biol Chem. |
TextSentencer_T7 | 966-979 | Sentence | denotes | 277:327-337). |
TextSentencer_T8 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
TextSentencer_T9 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
TextSentencer_T10 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
TextSentencer_T11 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
T3 | 761-766 | Sentence | denotes | 2002. |
T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
T6 | 953-979 | Sentence | denotes | J Biol Chem. 277:327-337). |
T7 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
T8 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
T9 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
T10 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
T3 | 761-766 | Sentence | denotes | 2002. |
T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
T6 | 953-965 | Sentence | denotes | J Biol Chem. |
T7 | 966-979 | Sentence | denotes | 277:327-337). |
T8 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
T9 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
T10 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
T11 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 88-91 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T2 | 88-91 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T3 | 92-95 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T4 | 92-95 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T5 | 122-125 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T6 | 122-125 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T7 | 351-354 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T8 | 351-354 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T9 | 413-416 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T10 | 413-416 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T11 | 485-508 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | N-acetylneuraminic acid |
T12 | 485-508 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | N-acetylneuraminic acid |
T13 | 510-516 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T14 | 555-561 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T15 | 577-586 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
T16 | 577-586 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
T17 | 616-622 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | Neu5Ac |
T18 | 1272-1275 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T19 | 1272-1275 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T20 | 1281-1284 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T21 | 1281-1284 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T22 | 1377-1380 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T23 | 1377-1380 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T24 | 1437-1440 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
T25 | 1437-1440 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
T26 | 1490-1493 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T27 | 1490-1493 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T28 | 1601-1604 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T29 | 1601-1604 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T30 | 1657-1660 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T31 | 1657-1660 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T32 | 1736-1747 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
T33 | 1755-1758 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T34 | 1755-1758 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T35 | 1790-1793 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
T36 | 1790-1793 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
T37 | 1896-1899 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T38 | 1896-1899 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T39 | 2005-2017 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acids |
T40 | 2057-2060 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
T41 | 2057-2060 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
T42 | 2142-2153 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 92-95 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
T2 | 1377-1380 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
T3 | 1437-1440 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
GlycoBiology-GDGDB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
_T1 | 702-704 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00386 | denotes | NM |
GlycoBiology-PACDB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
_T1 | 22-42 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC257,LEC564 | denotes | Campylobacter jejuni |
_T2 | 206-226 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC257,LEC564 | denotes | Campylobacter jejuni |
_T3 | 856-876 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC257,LEC564 | denotes | Campylobacter jejuni |
_T4 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 | denotes | Escherichia coli |
_T5 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 | denotes | Escherichia coli |
_T6 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 | denotes | Escherichia coli |
_T7 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 | denotes | Escherichia coli |
_T8 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 | denotes | Escherichia coli |
_T9 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 | denotes | Escherichia coli |
_T10 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 | denotes | Escherichia coli |
_T11 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 | denotes | Escherichia coli |
_T12 | 1128-1144 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 | denotes | Escherichia coli |
uniprot-human
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 485-508 | http://www.uniprot.org/uniprot/Q9BXD5 | denotes | N-acetylneuraminic acid |
T2 | 485-508 | http://www.uniprot.org/uniprot/Q9NR45 | denotes | N-acetylneuraminic acid |
T3 | 550-553 | http://www.uniprot.org/uniprot/P21941 | denotes | CMP |
T4 | 1991-1994 | http://www.uniprot.org/uniprot/P21941 | denotes | CMP |
T5 | 743-745 | http://www.uniprot.org/uniprot/P35318 | denotes | AM |
uniprot-mouse
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 743-745 | http://www.uniprot.org/uniprot/P97297 | denotes | AM |
GlycoBiology-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 22-42 | http://purl.bioontology.org/ontology/NCBITAXON/197 | denotes | Campylobacter jejuni |
T2 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538108 | denotes | bacterium |
T3 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538076 | denotes | bacterium |
T4 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538084 | denotes | bacterium |
T5 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538085 | denotes | bacterium |
T6 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538091 | denotes | bacterium |
T7 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538097 | denotes | bacterium |
T8 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538099 | denotes | bacterium |
T9 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538101 | denotes | bacterium |
T10 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538104 | denotes | bacterium |
T11 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/1368069 | denotes | bacterium |
T12 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538107 | denotes | bacterium |
T13 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538075 | denotes | bacterium |
T14 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538113 | denotes | bacterium |
T15 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538117 | denotes | bacterium |
T16 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/1730 | denotes | bacterium |
T17 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/138290 | denotes | bacterium |
T18 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/336403 | denotes | bacterium |
T19 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/336404 | denotes | bacterium |
T20 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/1144558 | denotes | bacterium |
T21 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/336405 | denotes | bacterium |
T22 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/674166 | denotes | bacterium |
T23 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/400048 | denotes | bacterium |
T24 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/538072 | denotes | bacterium |
T25 | 196-205 | http://purl.bioontology.org/ontology/NCBITAXON/336400 | denotes | bacterium |
T26 | 206-226 | http://purl.bioontology.org/ontology/NCBITAXON/197 | denotes | Campylobacter jejuni |
T27 | 658-665 | http://purl.bioontology.org/ontology/NCBITAXON/655550 | denotes | Gilbert |
T28 | 856-876 | http://purl.bioontology.org/ontology/NCBITAXON/197 | denotes | Campylobacter jejuni |
T29 | 1100-1106 | http://purl.bioontology.org/ontology/NCBITAXON/722432 | denotes | codons |
T30 | 1100-1106 | http://purl.bioontology.org/ontology/NCBITAXON/79338 | denotes | codons |
T31 | 1128-1139 | http://purl.bioontology.org/ontology/NCBITAXON/561 | denotes | Escherichia |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 157-183 | http://purl.obolibrary.org/obo/GO_0052798 | denotes | trans-sialidase activities |
T2 | 1677-1702 | http://purl.obolibrary.org/obo/GO_0052798 | denotes | trans-sialidase) activity |
T3 | 163-183 | http://purl.obolibrary.org/obo/GO_0004308 | denotes | sialidase activities |
T4 | 1510-1529 | http://purl.obolibrary.org/obo/GO_0004308 | denotes | sialidase) activity |
T5 | 1683-1702 | http://purl.obolibrary.org/obo/GO_0004308 | denotes | sialidase) activity |
T6 | 433-453 | http://purl.obolibrary.org/obo/GO_0004517 | denotes | synthase) activities |
T7 | 1397-1415 | http://purl.obolibrary.org/obo/GO_0004517 | denotes | synthase) activity |
T8 | 1916-1933 | http://purl.obolibrary.org/obo/GO_0004517 | denotes | synthase activity |
T9 | 878-890 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | Biosynthesis |
T10 | 894-904 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
T11 | 1583-1589 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
T12 | 1206-1234 | http://purl.obolibrary.org/obo/GO_0008373 | denotes | sialyltransferase activities |
T13 | 1259-1268 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T14 | 1424-1433 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T15 | 2044-2053 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T16 | 1991-2011 | http://purl.obolibrary.org/obo/GO_0008781 | denotes | CMP-activated sialic |
T17 | 1991-2017 | http://purl.obolibrary.org/obo/GO_0008781 | denotes | CMP-activated sialic acids |
T18 | 1991-2017 | http://purl.obolibrary.org/obo/GO_0047392 | denotes | CMP-activated sialic acids |
T19 | 1995-2017 | http://purl.obolibrary.org/obo/GO_0008747 | denotes | activated sialic acids |
T20 | 1995-2017 | http://purl.obolibrary.org/obo/GO_0015538 | denotes | activated sialic acids |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 931-935 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
GlycoBiology-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 196-205 | http://purl.obolibrary.org/obo/MAT_0000191 | denotes | bacterium |
GlyTouCan-IUPAC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
GlycanIUPAC_T1 | 510-516 | "http://rdf.glycoinfo.org/glycan/G76685HR" | denotes | Neu5Ac |
GlycanIUPAC_T2 | 555-561 | "http://rdf.glycoinfo.org/glycan/G76685HR" | denotes | Neu5Ac |
GlycanIUPAC_T3 | 616-622 | "http://rdf.glycoinfo.org/glycan/G76685HR" | denotes | Neu5Ac |
GlycanIUPAC_T4 | 510-516 | "http://rdf.glycoinfo.org/glycan/G65881BF" | denotes | Neu5Ac |
GlycanIUPAC_T5 | 555-561 | "http://rdf.glycoinfo.org/glycan/G65881BF" | denotes | Neu5Ac |
GlycanIUPAC_T6 | 616-622 | "http://rdf.glycoinfo.org/glycan/G65881BF" | denotes | Neu5Ac |
GlycanIUPAC_T7 | 510-516 | "http://rdf.glycoinfo.org/glycan/G82702MH" | denotes | Neu5Ac |
GlycanIUPAC_T8 | 555-561 | "http://rdf.glycoinfo.org/glycan/G82702MH" | denotes | Neu5Ac |
GlycanIUPAC_T9 | 616-622 | "http://rdf.glycoinfo.org/glycan/G82702MH" | denotes | Neu5Ac |
GlycanIUPAC_T10 | 510-516 | "http://rdf.glycoinfo.org/glycan/G51494MY" | denotes | Neu5Ac |
GlycanIUPAC_T11 | 555-561 | "http://rdf.glycoinfo.org/glycan/G51494MY" | denotes | Neu5Ac |
GlycanIUPAC_T12 | 616-622 | "http://rdf.glycoinfo.org/glycan/G51494MY" | denotes | Neu5Ac |
GlycanIUPAC_T13 | 510-516 | "http://rdf.glycoinfo.org/glycan/G37109XL" | denotes | Neu5Ac |
GlycanIUPAC_T14 | 555-561 | "http://rdf.glycoinfo.org/glycan/G37109XL" | denotes | Neu5Ac |
GlycanIUPAC_T15 | 616-622 | "http://rdf.glycoinfo.org/glycan/G37109XL" | denotes | Neu5Ac |
GlycanIUPAC_T16 | 510-516 | "http://rdf.glycoinfo.org/glycan/G47427MX" | denotes | Neu5Ac |
GlycanIUPAC_T17 | 555-561 | "http://rdf.glycoinfo.org/glycan/G47427MX" | denotes | Neu5Ac |
GlycanIUPAC_T18 | 616-622 | "http://rdf.glycoinfo.org/glycan/G47427MX" | denotes | Neu5Ac |
GlycanIUPAC_T19 | 510-516 | "http://rdf.glycoinfo.org/glycan/G89927NS" | denotes | Neu5Ac |
GlycanIUPAC_T20 | 555-561 | "http://rdf.glycoinfo.org/glycan/G89927NS" | denotes | Neu5Ac |
GlycanIUPAC_T21 | 616-622 | "http://rdf.glycoinfo.org/glycan/G89927NS" | denotes | Neu5Ac |
GlycoBiology-Epitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoEpitope-B_T1 | 92-95 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
PD-GlycoEpitope-B_T2 | 1377-1380 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
PD-GlycoEpitope-B_T3 | 1437-1440 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 88-91 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T2 | 92-95 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T3 | 122-125 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T4 | 351-354 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T5 | 413-416 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T6 | 510-516 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T7 | 555-561 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T8 | 590-597 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
T9 | 616-622 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T10 | 1272-1275 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T11 | 1281-1284 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T12 | 1377-1380 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T13 | 1437-1440 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T14 | 1490-1493 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T15 | 1601-1604 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T16 | 1657-1660 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T17 | 1755-1758 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T18 | 1790-1793 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T19 | 1896-1899 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T20 | 2057-2060 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 92-95 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
T2 | 1377-1380 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
T3 | 1437-1440 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
GlyCosmos15-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 22-42 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T2 | 206-226 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T3 | 856-876 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T4 | 1128-1144 | OrganismTaxon | denotes | Escherichia coli | 562 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
TextSentencer_T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
TextSentencer_T3 | 761-766 | Sentence | denotes | 2002. |
TextSentencer_T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
TextSentencer_T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
TextSentencer_T6 | 953-965 | Sentence | denotes | J Biol Chem. |
TextSentencer_T7 | 966-979 | Sentence | denotes | 277:327-337). |
TextSentencer_T8 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
TextSentencer_T9 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
TextSentencer_T10 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
TextSentencer_T11 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
T3 | 761-766 | Sentence | denotes | 2002. |
T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
T6 | 953-979 | Sentence | denotes | J Biol Chem. 277:327-337). |
T7 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
T8 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
T9 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
T10 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
T3 | 761-766 | Sentence | denotes | 2002. |
T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
T6 | 953-965 | Sentence | denotes | J Biol Chem. |
T7 | 966-979 | Sentence | denotes | 277:327-337). |
T8 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
T9 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
T10 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
T11 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-184 | Sentence | denotes | Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. |
T2 | 185-760 | Sentence | denotes | CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both alpha2,3-sialyltransferase (GM3 oligosaccharide synthase) and alpha2,8-sialyltransferase (GD3 oligosaccharide synthase) activities which catalyze the transfer of N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphate (CMP)-Neu5Ac to C-3' of the galactose in lactose and to C-8 of the Neu5Ac in 3'-sialyllactose, respectively (Gilbert M, Karwaski MF, Bernatchez S, Young NM, Taboada E, Michniewicz J, Cunningham AM, Wakarchuk WW. |
T3 | 761-766 | Sentence | denotes | 2002. |
T4 | 767-877 | Sentence | denotes | The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. |
T5 | 878-952 | Sentence | denotes | Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. |
T6 | 953-979 | Sentence | denotes | J Biol Chem. 277:327-337). |
T7 | 980-1163 | Sentence | denotes | We report here the characterization of a truncated CstII mutant (CstIIDelta32(I53S)) cloned from a synthetic gene whose codons are optimized for an Escherichia coli expression system. |
T8 | 1164-1457 | Sentence | denotes | In addition to the alpha2,3- and alpha2,8-sialyltransferase activities reported before for the synthesis of GM3- and GD3-type oligosaccharides, respectively, the CstIIDelta32(I53S) has alpha2,8-sialyltransferase (GT3 oligosaccharide synthase) activity for the synthesis of GT3 oligosaccharide. |
T9 | 1458-1831 | Sentence | denotes | It also has alpha2,8-sialidase (GD3 oligosaccharide sialidase) activity that catalyzes the specific cleavage of the alpha2,8-sialyl linkage of GD3-type oligosaccharides and alpha2,8-trans-sialidase (GD3 oligosaccharide trans-sialidase) activity that catalyzes the transfer of a sialic acid from a GD3 oligosaccharide to a different GM3 oligosaccharide (3'-sialyllactoside). |
T10 | 1832-2154 | Sentence | denotes | The donor substrate specificity study of the CstIIDelta32(I53S) GD3 oligosaccharide synthase activity indicates that the enzyme is flexible in using different CMP-activated sialic acids and their analogs for the synthesis of GD3 oligosaccharides containing natural and nonnatural modifications at the terminal sialic acid. |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 88-91 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T2 | 92-95 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T3 | 122-125 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T4 | 351-354 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T5 | 413-416 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T6 | 510-516 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T7 | 555-561 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T8 | 590-597 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
T9 | 616-622 | Glycan | denotes | Neu5Ac | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
T10 | 1272-1275 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T11 | 1281-1284 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T12 | 1377-1380 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T13 | 1437-1440 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
T14 | 1490-1493 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T15 | 1601-1604 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T16 | 1657-1660 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T17 | 1755-1758 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T18 | 1790-1793 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
T19 | 1896-1899 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
T20 | 2057-2060 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 92-95 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
T2 | 1377-1380 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
T3 | 1437-1440 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 22-42 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T2 | 206-226 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T3 | 856-876 | OrganismTaxon | denotes | Campylobacter jejuni | 197 |
T4 | 1128-1144 | OrganismTaxon | denotes | Escherichia coli | 562 |