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PubMed:1850841 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 103-112 DiseaseOrPhenotypicFeature denotes infection 0005550
T2 147-162 DiseaseOrPhenotypicFeature denotes (EBV) infection 0005111
T3 506-515 DiseaseOrPhenotypicFeature denotes infection 0005550
T4 1263-1272 DiseaseOrPhenotypicFeature denotes infection 0005550

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 13-49 protein denotes Epstein-Barr virus nuclear antigen 2
T2 53-67 DNA denotes viral promoter
T3 166-185 cell_type denotes human B lymphocytes
T4 187-212 protein denotes six viral nuclear antigen
T5 214-219 protein denotes EBNAs
T6 240-264 RNA denotes long primary transcripts
T7 277-297 RNA denotes alternative splicing
T8 302-337 RNA denotes alternative polyadenylylation sites
T9 382-391 DNA denotes promoters
T10 393-395 DNA denotes Cp
T11 519-540 cell_type denotes primary B lymphocytes
T12 566-568 DNA denotes Cp
T13 672-678 protein denotes EBNA 2
T14 706-708 DNA denotes Cp
T15 718-739 cell_type denotes primary B lymphocytes
T16 782-784 DNA denotes Cp
T17 805-828 DNA denotes -429 to -245 base pairs
T18 841-843 DNA denotes Cp
T19 861-863 DNA denotes Cp
T20 876-889 cell_type denotes B lymphocytes
T21 918-951 DNA denotes upstream and downstream sequences
T22 983-1008 DNA denotes EBNA 2-dependent enhancer
T23 1019-1026 protein denotes DNase I
T24 1070-1089 cell_type denotes B and T lymphocytes
T25 1101-1126 DNA denotes B-cell-specific footprint
T26 1148-1173 DNA denotes EBNA 2-dependent enhancer
T27 1209-1223 DNA denotes viral promoter
T28 1321-1327 protein denotes EBNA 2
T29 1355-1357 DNA denotes Cp
T30 1370-1395 DNA denotes EBNA 2-dependent enhancer

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-113 Sentence denotes Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection.
S2 114-338 Sentence denotes During latent Epstein-Barr virus (EBV) infection of human B lymphocytes, six viral nuclear antigen (EBNAs) are expressed from long primary transcripts by means of alternative splicing and alternative polyadenylylation sites.
S3 339-449 Sentence denotes These transcripts initiate from one of two promoters, Cp or Wp, that function in a mutually exclusive fashion.
S4 450-575 Sentence denotes Wp is exclusively utilized during the initial stages of infection of primary B lymphocytes, followed by a switch to Cp usage.
S5 576-1174 Sentence denotes These studies have been extended to show that (i) a mutant EBV strain lacking the gene encoding EBNA 2 fails to switch from Wp to Cp usage in primary B lymphocytes, although the virus contains a functional Cp; (ii) a region from -429 to -245 base pairs upstream of Cp is essential for Cp activity in B lymphocytes, but only in the context of upstream and downstream sequences; (iii) this region contains an EBNA 2-dependent enhancer; and (iv) DNase I protection employing nuclear extracts from B and T lymphocytes revealed a B-cell-specific footprint in the region of the EBNA 2-dependent enhancer.
S6 1175-1396 Sentence denotes These results support a model for viral promoter switching during the initial stages of infection in which Wp activity leads to the expression of EBNA 2, followed by activation of Cp through the EBNA 2-dependent enhancer.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 9-31 NP denotes the Epstein-Barr virus
C2 128-152 NP denotes Epstein-Barr virus (EBV)
C3 166-185 NP denotes human B lymphocytes
C4 191-220 NP denotes viral nuclear antigen (EBNAs)
C5 371-391 NP denotes one of two promoters
C7 393-395 NP denotes Cp
C8 399-401 NP denotes Wp
C6 393-401 NP denotes Cp or Wp
C9 403-407 NP denotes that
C10 450-452 NP denotes Wp
C11 519-540 NP denotes primary B lymphocytes
C12 566-568 NP denotes Cp
C13 626-638 NP denotes a mutant EBV
C14 672-678 NP denotes EBNA 2
C15 700-702 NP denotes Wp
C16 706-708 NP denotes Cp
C17 718-739 NP denotes primary B lymphocytes
C18 769-784 NP denotes a functional Cp
C20 841-843 NP denotes Cp
C19 791-843 NP denotes a region from -429 to -245 base pairs upstream of Cp
C21 876-889 NP denotes B lymphocytes
C22 959-970 NP denotes this region
C24 983-989 NP denotes EBNA 2
C23 980-1008 NP denotes an EBNA 2-dependent enhancer
C26 1148-1154 NP denotes EBNA 2
C25 1144-1173 NP denotes the EBNA 2-dependent enhancer
C27 1321-1327 NP denotes EBNA 2
C28 1355-1357 NP denotes Cp
C30 1370-1376 NP denotes EBNA 2
C29 1366-1395 NP denotes the EBNA 2-dependent enhancer
R1 C2 C1 coref-ident Epstein-Barr virus (EBV),the Epstein-Barr virus
R2 C5 C6 coref-appos one of two promoters,Cp or Wp
R3 C9 C6 coref-relat that,Cp or Wp
R4 C10 C8 coref-ident Wp,Wp
R5 C11 C3 coref-other primary B lymphocytes,human B lymphocytes
R6 C12 C7 coref-ident Cp,Cp
R7 C13 C2 coref-other a mutant EBV,Epstein-Barr virus (EBV)
R8 C15 C10 coref-ident Wp,Wp
R9 C16 C12 coref-ident Cp,Cp
R10 C17 C11 coref-ident primary B lymphocytes,primary B lymphocytes
R11 C18 C16 coref-other a functional Cp,Cp
R12 C20 C16 coref-ident Cp,Cp
R13 C21 C17 coref-other B lymphocytes,primary B lymphocytes
R14 C22 C19 coref-ident this region,a region from -429 to -245 base pairs upstream of Cp
R15 C24 C14 coref-ident EBNA 2,EBNA 2
R16 C23 C14 coref-other an EBNA 2-dependent enhancer,EBNA 2
R17 C26 C24 coref-ident EBNA 2,EBNA 2
R18 C25 C23 coref-ident the EBNA 2-dependent enhancer,an EBNA 2-dependent enhancer
R19 C27 C26 coref-ident EBNA 2,EBNA 2
R20 C28 C20 coref-ident Cp,Cp
R21 C30 C27 coref-ident EBNA 2,EBNA 2
R22 C29 C25 coref-ident the EBNA 2-dependent enhancer,the EBNA 2-dependent enhancer

GENIAcorpus

Id Subject Object Predicate Lexical cue
T28 876-889 cell_type denotes B lymphocytes
T29 918-926 DNA_domain_or_region denotes upstream
T30 931-951 DNA_domain_or_region denotes downstream sequences
T31 983-989 protein_molecule denotes EBNA 2
T32 1019-1026 protein_molecule denotes DNase I
T33 1048-1064 cell_component denotes nuclear extracts
T34 1101-1126 DNA_domain_or_region denotes B-cell-specific footprint
T35 1148-1154 protein_molecule denotes EBNA 2
T36 1209-1223 DNA_domain_or_region denotes viral promoter
T37 1263-1272 other_name denotes infection
T38 1282-1284 DNA_substructure denotes Wp
T39 1321-1327 protein_molecule denotes EBNA 2
T40 1355-1357 DNA_domain_or_region denotes Cp
T41 1370-1376 protein_molecule denotes EBNA 2
T2 53-67 DNA_domain_or_region denotes viral promoter
T3 103-112 other_name denotes infection
T4 128-146 virus denotes Epstein-Barr virus
T5 148-151 virus denotes EBV
T6 166-185 cell_type denotes human B lymphocytes
T7 187-212 protein_family_or_group denotes six viral nuclear antigen
T8 214-219 protein_family_or_group denotes EBNAs
T9 240-264 RNA_family_or_group denotes long primary transcripts
T10 277-297 RNA_domain_or_region denotes alternative splicing
T11 302-337 RNA_domain_or_region denotes alternative polyadenylylation sites
T12 382-391 DNA_domain_or_region denotes promoters
T13 393-395 DNA_domain_or_region denotes Cp
T14 399-401 DNA_substructure denotes Wp
T15 450-452 DNA_substructure denotes Wp
T16 506-515 other_name denotes infection
T17 519-540 cell_type denotes primary B lymphocytes
T18 566-568 DNA_domain_or_region denotes Cp
T19 628-645 virus denotes mutant EBV strain
T20 672-678 protein_molecule denotes EBNA 2
T21 700-702 DNA_substructure denotes Wp
T22 706-708 DNA_domain_or_region denotes Cp
T23 718-739 cell_type denotes primary B lymphocytes
T24 782-784 DNA_domain_or_region denotes Cp
T25 805-828 DNA_domain_or_region denotes -429 to -245 base pairs
T26 841-843 DNA_domain_or_region denotes Cp
T27 861-863 DNA_domain_or_region denotes Cp
T1 13-31 virus denotes Epstein-Barr virus