PubMed:18457324
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-207 | Sentence | denotes | Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer. |
| T2 | 208-219 | Sentence | denotes | BACKGROUND: |
| T3 | 220-348 | Sentence | denotes | Exposure to anthracyclines as part of cancer therapy has been associated with the development of congestive heart failure (CHF). |
| T4 | 349-443 | Sentence | denotes | The potential role of genetic risk factors in anthracycline-related CHF remains to be defined. |
| T5 | 444-779 | Sentence | denotes | Thus, in this study, the authors examined whether common polymorphisms in candidate genes involved in the pharmacodynamics of anthracyclines (in particular, the nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase 1 gene NQO1 and the carbonyl reductase 3 gene CBR3) had an impact on the risk of anthracycline-related CHF. |
| T6 | 780-788 | Sentence | denotes | METHODS: |
| T7 | 789-977 | Sentence | denotes | A nested case-control study was conducted within a cohort of 1979 patients enrolled in the Childhood Cancer Survivor Study who received treatment with anthracyclines and had available DNA. |
| T8 | 978-1172 | Sentence | denotes | Thirty patients with CHF (cases) and 115 matched controls were genotyped for polymorphisms in NQO1 (NQO1*2) and CBR3 (the CBR3 valine [V] to methionine [M] substitution at position 244 [V244M]). |
| T9 | 1173-1375 | Sentence | denotes | Enzyme activity assays with recombinant CBR3 isoforms (CBR3 V244 and CBR3 M244) and the anthracycline substrate doxorubicin were used to investigate the functional impact of the CBR3 V244M polymorphism. |
| T10 | 1376-1384 | Sentence | denotes | RESULTS: |
| T11 | 1385-1578 | Sentence | denotes | Multivariate analyses adjusted for sex and primary disease recurrence were used to test for associations between the candidate genetic polymorphisms (NQO1*2 and CBR3 V244M) and the risk of CHF. |
| T12 | 1579-1718 | Sentence | denotes | Analyses indicated no association between the NQO1*2 polymorphism and the risk of anthracycline-related CHF (odds ratio [OR], 1.04; P=.97). |
| T13 | 1719-1882 | Sentence | denotes | There was a trend toward an association between the CBR3 V244M polymorphism and the risk of CHF (OR, 8.16; P=.056 for G/G vs A/A; OR, 5.44; P=.092 for G/A vs A/A). |
| T14 | 1883-2105 | Sentence | denotes | In line, recombinant CBR3 V244 (G allele) synthesized 2.6-fold more cardiotoxic doxorubicinol per unit of time than CBR3 M244 (A allele; CBR3 V244 [8.26+/-3.57 nmol/hour.mg] vs CBR3 M244 [3.22+/-0.67 nmol/hour.mg]; P=.01). |
| T15 | 2106-2118 | Sentence | denotes | CONCLUSIONS: |
| T16 | 2119-2341 | Sentence | denotes | The functional CBR3 V244M polymorphism may have an impact on the risk of anthracycline-related CHF among childhood cancer survivors by modulating the intracardiac formation of cardiotoxic anthracycline alcohol metabolites. |
| T17 | 2342-2397 | Sentence | denotes | Larger confirmatory case-control studies are warranted. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 5009 | 29-49 | GeneOrGeneProduct | denotes | carbonyl reductase 3 | NCBIGene:874 |
| 5010 | 55-59 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5011 | 68-100 | GeneOrGeneProduct | denotes | NAD(P)H:quinone oxidoreductase 1 | NCBIGene:1728 |
| 5012 | 106-110 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5013 | 114-122 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 5014 | 137-150 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5015 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | MESH:D006333 |
| 5016 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | MESH:D009369 |
| 5017 | 232-246 | ChemicalEntity | denotes | anthracyclines | MESH:D018943 |
| 5018 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | MESH:D009369 |
| 5019 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | MESH:D006333 |
| 5020 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5021 | 395-408 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5022 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5023 | 570-584 | ChemicalEntity | denotes | anthracyclines | MESH:D018943 |
| 5024 | 605-673 | GeneOrGeneProduct | denotes | nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase 1 | NCBIGene:1728 |
| 5025 | 679-683 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5026 | 692-712 | GeneOrGeneProduct | denotes | carbonyl reductase 3 | NCBIGene:874 |
| 5027 | 718-722 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5028 | 753-766 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5029 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5030 | 855-863 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 5031 | 940-954 | ChemicalEntity | denotes | anthracyclines | MESH:D018943 |
| 5032 | 985-993 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 5033 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5034 | 1072-1076 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5035 | 1078-1082 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5036 | 1090-1094 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5037 | 1100-1104 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5038 | 1105-1162 | SequenceVariant | denotes | valine [V] to methionine [M] substitution at position 244 | DBSNP:rs1056892 |
| 5039 | 1164-1169 | SequenceVariant | denotes | V244M | DBSNP:rs1056892 |
| 5040 | 1213-1217 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5041 | 1228-1232 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5042 | 1233-1237 | SequenceVariant | denotes | V244 | DBSNP:rs1056892 |
| 5043 | 1242-1246 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5044 | 1247-1251 | SequenceVariant | denotes | M244 | DBSNP:rs1056892 |
| 5045 | 1261-1274 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5046 | 1285-1296 | ChemicalEntity | denotes | doxorubicin | MESH:D004317 |
| 5047 | 1351-1355 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5048 | 1356-1361 | SequenceVariant | denotes | V244M | DBSNP:rs1056892 |
| 5049 | 1535-1539 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5050 | 1546-1550 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5051 | 1551-1556 | SequenceVariant | denotes | V244M | DBSNP:rs1056892 |
| 5052 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5053 | 1625-1629 | GeneOrGeneProduct | denotes | NQO1 | NCBIGene:1728 |
| 5054 | 1661-1674 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5055 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5056 | 1771-1775 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5057 | 1776-1781 | SequenceVariant | denotes | V244M | DBSNP:rs1056892 |
| 5058 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5059 | 1904-1908 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5060 | 1909-1913 | SequenceVariant | denotes | V244 | DBSNP:rs1056892 |
| 5061 | 1951-1962 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | MESH:D066126 |
| 5062 | 1963-1976 | ChemicalEntity | denotes | doxorubicinol | MESH:C010013 |
| 5063 | 1999-2003 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5064 | 2004-2008 | SequenceVariant | denotes | M244 | DBSNP:rs1056892 |
| 5065 | 2020-2024 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5066 | 2025-2029 | SequenceVariant | denotes | V244 | DBSNP:rs1056892 |
| 5067 | 2060-2064 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5068 | 2065-2069 | SequenceVariant | denotes | M244 | DBSNP:rs1056892 |
| 5069 | 2134-2138 | GeneOrGeneProduct | denotes | CBR3 | NCBIGene:874 |
| 5070 | 2139-2144 | SequenceVariant | denotes | V244M | DBSNP:rs1056892 |
| 5071 | 2192-2205 | ChemicalEntity | denotes | anthracycline | MESH:D018943 |
| 5072 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | MESH:D006333 |
| 5073 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | MESH:D009369 |
| 5074 | 2295-2306 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | MESH:D066126 |
| 5075 | 2307-2328 | ChemicalEntity | denotes | anthracycline alcohol | MESH:D000438|MESH:D018943 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | 0005009 |
| T2 | 170-183 | DiseaseOrPhenotypicFeature | denotes | heart failure | 0005252 |
| T3 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | 0004992 |
| T4 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | 0004992 |
| T5 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | 0005009 |
| T6 | 328-341 | DiseaseOrPhenotypicFeature | denotes | heart failure | 0005252 |
| T7 | 890-896 | DiseaseOrPhenotypicFeature | denotes | Cancer | 0004992 |
| T8 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | 0004992 |
LitCoin-SeqVar
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1164-1169 | SequenceVariant | denotes | V244M |
| T2 | 1356-1361 | SequenceVariant | denotes | V244M |
| T3 | 1551-1556 | SequenceVariant | denotes | V244M |
| T4 | 1776-1781 | SequenceVariant | denotes | V244M |
| T5 | 2139-2144 | SequenceVariant | denotes | V244M |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 29-49 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T2 | 55-59 | GeneOrGeneProduct | denotes | CBR3 |
| T3 | 68-100 | GeneOrGeneProduct | denotes | NAD(P)H:quinone oxidoreductase 1 |
| T4 | 106-110 | GeneOrGeneProduct | denotes | NQO1 |
| T5 | 170-175 | GeneOrGeneProduct | denotes | heart |
| T6 | 328-333 | GeneOrGeneProduct | denotes | heart |
| T7 | 657-671 | GeneOrGeneProduct | denotes | oxidoreductase |
| T8 | 679-683 | GeneOrGeneProduct | denotes | NQO1 |
| T9 | 692-712 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T10 | 718-722 | GeneOrGeneProduct | denotes | CBR3 |
| T11 | 731-737 | GeneOrGeneProduct | denotes | impact |
| T12 | 791-797 | GeneOrGeneProduct | denotes | nested |
| T13 | 1072-1076 | GeneOrGeneProduct | denotes | NQO1 |
| T14 | 1078-1082 | GeneOrGeneProduct | denotes | NQO1 |
| T15 | 1090-1094 | GeneOrGeneProduct | denotes | CBR3 |
| T16 | 1100-1104 | GeneOrGeneProduct | denotes | CBR3 |
| T17 | 1173-1179 | GeneOrGeneProduct | denotes | Enzyme |
| T18 | 1213-1217 | GeneOrGeneProduct | denotes | CBR3 |
| T19 | 1228-1232 | GeneOrGeneProduct | denotes | CBR3 |
| T20 | 1242-1246 | GeneOrGeneProduct | denotes | CBR3 |
| T21 | 1337-1343 | GeneOrGeneProduct | denotes | impact |
| T22 | 1351-1355 | GeneOrGeneProduct | denotes | CBR3 |
| T23 | 1535-1539 | GeneOrGeneProduct | denotes | NQO1 |
| T24 | 1546-1550 | GeneOrGeneProduct | denotes | CBR3 |
| T25 | 1625-1629 | GeneOrGeneProduct | denotes | NQO1 |
| T26 | 1771-1775 | GeneOrGeneProduct | denotes | CBR3 |
| T27 | 1904-1908 | GeneOrGeneProduct | denotes | CBR3 |
| T28 | 1941-1945 | GeneOrGeneProduct | denotes | fold |
| T29 | 1999-2003 | GeneOrGeneProduct | denotes | CBR3 |
| T30 | 2020-2024 | GeneOrGeneProduct | denotes | CBR3 |
| T31 | 2060-2064 | GeneOrGeneProduct | denotes | CBR3 |
| T32 | 2134-2138 | GeneOrGeneProduct | denotes | CBR3 |
| T33 | 2170-2176 | GeneOrGeneProduct | denotes | impact |
| T34 | 2321-2328 | GeneOrGeneProduct | denotes | alcohol |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 29-49 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T2 | 55-59 | GeneOrGeneProduct | denotes | CBR3 |
| T3 | 68-100 | GeneOrGeneProduct | denotes | NAD(P)H:quinone oxidoreductase 1 |
| T4 | 106-110 | GeneOrGeneProduct | denotes | NQO1 |
| T5 | 159-169 | GeneOrGeneProduct | denotes | congestive |
| T6 | 170-175 | GeneOrGeneProduct | denotes | heart |
| T7 | 250-254 | GeneOrGeneProduct | denotes | part |
| T8 | 317-327 | GeneOrGeneProduct | denotes | congestive |
| T9 | 328-333 | GeneOrGeneProduct | denotes | heart |
| T10 | 384-391 | GeneOrGeneProduct | denotes | factors |
| T11 | 657-671 | GeneOrGeneProduct | denotes | oxidoreductase |
| T12 | 679-683 | GeneOrGeneProduct | denotes | NQO1 |
| T13 | 692-712 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T14 | 718-722 | GeneOrGeneProduct | denotes | CBR3 |
| T15 | 731-737 | GeneOrGeneProduct | denotes | impact |
| T16 | 780-787 | GeneOrGeneProduct | denotes | METHODS |
| T17 | 791-797 | GeneOrGeneProduct | denotes | nested |
| T18 | 798-802 | GeneOrGeneProduct | denotes | case |
| T19 | 963-972 | GeneOrGeneProduct | denotes | available |
| T20 | 1004-1009 | GeneOrGeneProduct | denotes | cases |
| T21 | 1072-1076 | GeneOrGeneProduct | denotes | NQO1 |
| T22 | 1078-1082 | GeneOrGeneProduct | denotes | NQO1 |
| T23 | 1090-1094 | GeneOrGeneProduct | denotes | CBR3 |
| T24 | 1100-1104 | GeneOrGeneProduct | denotes | CBR3 |
| T25 | 1173-1179 | GeneOrGeneProduct | denotes | Enzyme |
| T26 | 1180-1188 | GeneOrGeneProduct | denotes | activity |
| T27 | 1201-1212 | GeneOrGeneProduct | denotes | recombinant |
| T28 | 1213-1217 | GeneOrGeneProduct | denotes | CBR3 |
| T29 | 1228-1232 | GeneOrGeneProduct | denotes | CBR3 |
| T30 | 1242-1246 | GeneOrGeneProduct | denotes | CBR3 |
| T31 | 1337-1343 | GeneOrGeneProduct | denotes | impact |
| T32 | 1351-1355 | GeneOrGeneProduct | denotes | CBR3 |
| T33 | 1468-1472 | GeneOrGeneProduct | denotes | test |
| T34 | 1535-1539 | GeneOrGeneProduct | denotes | NQO1 |
| T35 | 1546-1550 | GeneOrGeneProduct | denotes | CBR3 |
| T36 | 1625-1629 | GeneOrGeneProduct | denotes | NQO1 |
| T37 | 1771-1775 | GeneOrGeneProduct | denotes | CBR3 |
| T38 | 1826-1832 | GeneOrGeneProduct | denotes | P=.056 |
| T39 | 1846-1851 | GeneOrGeneProduct | denotes | A; OR |
| T40 | 1859-1865 | GeneOrGeneProduct | denotes | P=.092 |
| T41 | 1886-1890 | GeneOrGeneProduct | denotes | line |
| T42 | 1892-1903 | GeneOrGeneProduct | denotes | recombinant |
| T43 | 1904-1908 | GeneOrGeneProduct | denotes | CBR3 |
| T44 | 1941-1945 | GeneOrGeneProduct | denotes | fold |
| T45 | 1977-1980 | GeneOrGeneProduct | denotes | per |
| T46 | 1989-1993 | GeneOrGeneProduct | denotes | time |
| T47 | 1999-2003 | GeneOrGeneProduct | denotes | CBR3 |
| T48 | 2020-2024 | GeneOrGeneProduct | denotes | CBR3 |
| T49 | 2060-2064 | GeneOrGeneProduct | denotes | CBR3 |
| T50 | 2134-2138 | GeneOrGeneProduct | denotes | CBR3 |
| T51 | 2170-2176 | GeneOrGeneProduct | denotes | impact |
| T52 | 2282-2291 | GeneOrGeneProduct | denotes | formation |
| T53 | 2321-2328 | GeneOrGeneProduct | denotes | alcohol |
| T54 | 2362-2366 | GeneOrGeneProduct | denotes | case |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T2 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T3 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T4 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T5 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T6 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T7 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T8 | 890-896 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
| T9 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T10 | 1436-1443 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
| T11 | 1444-1454 | DiseaseOrPhenotypicFeature | denotes | recurrence | D012008 |
| T12 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T13 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T14 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T15 | 1951-1962 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
| T16 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T17 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T18 | 2295-2306 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
| T19 | 2321-2328 | DiseaseOrPhenotypicFeature | denotes | alcohol | D000437 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 29-49 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T2 | 55-59 | GeneOrGeneProduct | denotes | CBR3 |
| T3 | 68-100 | GeneOrGeneProduct | denotes | NAD(P)H:quinone oxidoreductase 1 |
| T4 | 106-110 | GeneOrGeneProduct | denotes | NQO1 |
| T5 | 657-671 | GeneOrGeneProduct | denotes | oxidoreductase |
| T6 | 679-683 | GeneOrGeneProduct | denotes | NQO1 |
| T7 | 692-712 | GeneOrGeneProduct | denotes | carbonyl reductase 3 |
| T8 | 718-722 | GeneOrGeneProduct | denotes | CBR3 |
| T9 | 1072-1076 | GeneOrGeneProduct | denotes | NQO1 |
| T10 | 1078-1082 | GeneOrGeneProduct | denotes | NQO1 |
| T11 | 1090-1094 | GeneOrGeneProduct | denotes | CBR3 |
| T12 | 1100-1104 | GeneOrGeneProduct | denotes | CBR3 |
| T13 | 1213-1217 | GeneOrGeneProduct | denotes | CBR3 |
| T14 | 1228-1232 | GeneOrGeneProduct | denotes | CBR3 |
| T15 | 1242-1246 | GeneOrGeneProduct | denotes | CBR3 |
| T16 | 1351-1355 | GeneOrGeneProduct | denotes | CBR3 |
| T17 | 1535-1539 | GeneOrGeneProduct | denotes | NQO1 |
| T18 | 1546-1550 | GeneOrGeneProduct | denotes | CBR3 |
| T19 | 1625-1629 | GeneOrGeneProduct | denotes | NQO1 |
| T20 | 1771-1775 | GeneOrGeneProduct | denotes | CBR3 |
| T21 | 1904-1908 | GeneOrGeneProduct | denotes | CBR3 |
| T22 | 1999-2003 | GeneOrGeneProduct | denotes | CBR3 |
| T23 | 2020-2024 | GeneOrGeneProduct | denotes | CBR3 |
| T24 | 2060-2064 | GeneOrGeneProduct | denotes | CBR3 |
| T25 | 2134-2138 | GeneOrGeneProduct | denotes | CBR3 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 68-71 | DiseaseOrPhenotypicFeature | denotes | NAD | 0009755 |
| T2 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | 0005009 |
| T3 | 190-206 | DiseaseOrPhenotypicFeature | denotes | childhood cancer | 0006517 |
| T4 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | 0005009 |
| T5 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T6 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T7 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T8 | 880-896 | DiseaseOrPhenotypicFeature | denotes | Childhood Cancer | 0006517 |
| T9 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T10 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T11 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T12 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T13 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | 0005009 |
| T14 | 2224-2240 | DiseaseOrPhenotypicFeature | denotes | childhood cancer | 0006517 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T2 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T3 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T4 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T5 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T6 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T7 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T8 | 890-896 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
| T9 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T10 | 1436-1443 | DiseaseOrPhenotypicFeature | denotes | disease | D004194 |
| T11 | 1444-1454 | DiseaseOrPhenotypicFeature | denotes | recurrence | D012008 |
| T12 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T13 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T14 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T15 | 1951-1962 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
| T16 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T17 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T18 | 2295-2306 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T2 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T3 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T4 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 |
| T5 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T6 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T7 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T8 | 890-896 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 |
| T9 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T10 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T11 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T12 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T13 | 1951-1962 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
| T14 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 |
| T15 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 |
| T16 | 2295-2306 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 29-47 | ChemicalEntity | denotes | carbonyl reductase | D000429 |
| T2 | 68-74 | ChemicalEntity | denotes | NAD(P) | http://purl.obolibrary.org/obo/CHEBI_25524 |
| T3 | 84-98 | ChemicalEntity | denotes | oxidoreductase | D010088 |
| T4 | 137-150 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T6 | 232-246 | ChemicalEntity | denotes | anthracyclines | D018943|http://purl.obolibrary.org/obo/CHEBI_49322|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T9 | 395-408 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T11 | 570-584 | ChemicalEntity | denotes | anthracyclines | D018943|http://purl.obolibrary.org/obo/CHEBI_49322|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T14 | 605-617 | ChemicalEntity | denotes | nicotinamide | D009536|http://purl.obolibrary.org/obo/CHEBI_17154 |
| T16 | 618-625 | ChemicalEntity | denotes | adenine | D000225|http://purl.obolibrary.org/obo/CHEBI_16708 |
| T18 | 657-671 | ChemicalEntity | denotes | oxidoreductase | D010088 |
| T19 | 692-710 | ChemicalEntity | denotes | carbonyl reductase | D000429 |
| T20 | 753-766 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T22 | 940-954 | ChemicalEntity | denotes | anthracyclines | D018943|http://purl.obolibrary.org/obo/CHEBI_49322|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T25 | 1105-1111 | ChemicalEntity | denotes | valine | http://purl.obolibrary.org/obo/CHEBI_27266 |
| T26 | 1119-1129 | ChemicalEntity | denotes | methionine | http://purl.obolibrary.org/obo/CHEBI_64558|http://purl.obolibrary.org/obo/CHEBI_16811 |
| T28 | 1261-1274 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T30 | 1285-1296 | ChemicalEntity | denotes | doxorubicin | D004317|http://purl.obolibrary.org/obo/CHEBI_64816|http://purl.obolibrary.org/obo/CHEBI_28748 |
| T33 | 1661-1674 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T35 | 1963-1976 | ChemicalEntity | denotes | doxorubicinol | C010013|http://purl.obolibrary.org/obo/CHEBI_133817 |
| T37 | 2192-2205 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T39 | 2307-2320 | ChemicalEntity | denotes | anthracycline | D018943|http://purl.obolibrary.org/obo/CHEBI_48120 |
| T41 | 2321-2328 | ChemicalEntity | denotes | alcohol | http://purl.obolibrary.org/obo/CHEBI_30879|http://purl.obolibrary.org/obo/CHEBI_16236|ChemicalEntity |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 114-122 | OrganismTaxon | denotes | patients |
| T2 | 855-863 | OrganismTaxon | denotes | patients |
| T3 | 985-993 | OrganismTaxon | denotes | patients |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T41 | 2321-2328 | ChemicalEntity | denotes | alcohol | ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_16236|http://purl.obolibrary.org/obo/CHEBI_30879 | |
| T39 | 2307-2320 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T37 | 2192-2205 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T35 | 1963-1976 | ChemicalEntity | denotes | doxorubicinol | http://purl.obolibrary.org/obo/CHEBI_133817|C010013 | |
| T33 | 1661-1674 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T30 | 1285-1296 | ChemicalEntity | denotes | doxorubicin | http://purl.obolibrary.org/obo/CHEBI_28748|http://purl.obolibrary.org/obo/CHEBI_64816|D004317 | |
| T28 | 1261-1274 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T26 | 1119-1129 | ChemicalEntity | denotes | methionine | http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558 | |
| T25 | 1105-1111 | ChemicalEntity | denotes | valine | http://purl.obolibrary.org/obo/CHEBI_27266 | |
| T22 | 940-954 | ChemicalEntity | denotes | anthracyclines | http://purl.obolibrary.org/obo/CHEBI_48120|http://purl.obolibrary.org/obo/CHEBI_49322|D018943 | |
| T20 | 753-766 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T19 | 692-710 | ChemicalEntity | denotes | carbonyl reductase | D000429 | |
| T18 | 657-671 | ChemicalEntity | denotes | oxidoreductase | D010088 | |
| T16 | 618-625 | ChemicalEntity | denotes | adenine | http://purl.obolibrary.org/obo/CHEBI_16708|D000225 | |
| T14 | 605-617 | ChemicalEntity | denotes | nicotinamide | http://purl.obolibrary.org/obo/CHEBI_17154|D009536 | |
| T11 | 570-584 | ChemicalEntity | denotes | anthracyclines | http://purl.obolibrary.org/obo/CHEBI_48120|http://purl.obolibrary.org/obo/CHEBI_49322|D018943 | |
| T9 | 395-408 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T6 | 232-246 | ChemicalEntity | denotes | anthracyclines | http://purl.obolibrary.org/obo/CHEBI_48120|http://purl.obolibrary.org/obo/CHEBI_49322|D018943 | |
| T4 | 137-150 | ChemicalEntity | denotes | anthracycline | http://purl.obolibrary.org/obo/CHEBI_48120|D018943 | |
| T3 | 84-98 | ChemicalEntity | denotes | oxidoreductase | D010088 | |
| T2 | 68-74 | ChemicalEntity | denotes | NAD(P) | http://purl.obolibrary.org/obo/CHEBI_25524 | |
| T1 | 29-47 | ChemicalEntity | denotes | carbonyl reductase | D000429 | |
| T95686 | 2134-2138 | GeneOrGeneProduct | denotes | CBR3 | ||
| T24 | 2060-2064 | GeneOrGeneProduct | denotes | CBR3 | ||
| T23 | 2020-2024 | GeneOrGeneProduct | denotes | CBR3 | ||
| T68344 | 1999-2003 | GeneOrGeneProduct | denotes | CBR3 | ||
| T21 | 1904-1908 | GeneOrGeneProduct | denotes | CBR3 | ||
| T41939 | 1771-1775 | GeneOrGeneProduct | denotes | CBR3 | ||
| T57228 | 1625-1629 | GeneOrGeneProduct | denotes | NQO1 | ||
| T50863 | 1546-1550 | GeneOrGeneProduct | denotes | CBR3 | ||
| T17 | 1535-1539 | GeneOrGeneProduct | denotes | NQO1 | ||
| T48682 | 1351-1355 | GeneOrGeneProduct | denotes | CBR3 | ||
| T15 | 1242-1246 | GeneOrGeneProduct | denotes | CBR3 | ||
| T87641 | 1228-1232 | GeneOrGeneProduct | denotes | CBR3 | ||
| T13 | 1213-1217 | GeneOrGeneProduct | denotes | CBR3 | ||
| T12 | 1100-1104 | GeneOrGeneProduct | denotes | CBR3 | ||
| T72894 | 1090-1094 | GeneOrGeneProduct | denotes | CBR3 | ||
| T10 | 1078-1082 | GeneOrGeneProduct | denotes | NQO1 | ||
| T58613 | 1072-1076 | GeneOrGeneProduct | denotes | NQO1 | ||
| T8 | 718-722 | GeneOrGeneProduct | denotes | CBR3 | ||
| T7 | 692-712 | GeneOrGeneProduct | denotes | carbonyl reductase 3 | ||
| T90380 | 679-683 | GeneOrGeneProduct | denotes | NQO1 | ||
| T5 | 657-671 | GeneOrGeneProduct | denotes | oxidoreductase | ||
| T11394 | 106-110 | GeneOrGeneProduct | denotes | NQO1 | ||
| T14203 | 68-100 | GeneOrGeneProduct | denotes | NAD(P)H:quinone oxidoreductase 1 | ||
| T21184 | 55-59 | GeneOrGeneProduct | denotes | CBR3 | ||
| T84592 | 29-49 | GeneOrGeneProduct | denotes | carbonyl reductase 3 | ||
| T59716 | 2295-2306 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 | |
| T37170 | 2234-2240 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 | |
| T1373 | 2214-2217 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T74026 | 1951-1962 | DiseaseOrPhenotypicFeature | denotes | cardiotoxic | D066126 | |
| T47091 | 1811-1814 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T71129 | 1683-1686 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T25005 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T76722 | 999-1002 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T82642 | 890-896 | DiseaseOrPhenotypicFeature | denotes | Cancer | D009369 | |
| T71737 | 775-778 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T10819 | 417-420 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T78834 | 343-346 | DiseaseOrPhenotypicFeature | denotes | CHF | D006333 | |
| T52963 | 317-341 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 | |
| T46478 | 258-264 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 | |
| T36404 | 200-206 | DiseaseOrPhenotypicFeature | denotes | cancer | D009369 | |
| T39650 | 159-183 | DiseaseOrPhenotypicFeature | denotes | congestive heart failure | D006333 | |
| T64646 | 985-993 | OrganismTaxon | denotes | patients | ||
| T69553 | 855-863 | OrganismTaxon | denotes | patients | ||
| T49432 | 114-122 | OrganismTaxon | denotes | patients | ||
| T94145 | 2139-2144 | SequenceVariant | denotes | V244M | ||
| T23586 | 1776-1781 | SequenceVariant | denotes | V244M | ||
| T80276 | 1551-1556 | SequenceVariant | denotes | V244M | ||
| T56558 | 1356-1361 | SequenceVariant | denotes | V244M | ||
| T5015 | 1164-1169 | SequenceVariant | denotes | V244M |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 2134-2138 | gene:874 | denotes | CBR3 |
| T1 | 2214-2217 | disease:C0018802 | denotes | CHF |
| R1 | T0 | T1 | associated_with | CBR3,CHF |
DisGeNET5_variant_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 18457324-11#20#25#geners1056892 | 2139-2144 | geners1056892 | denotes | V244M |
| 18457324-11#95#98#diseaseC0018802 | 2214-2217 | diseaseC0018802 | denotes | CHF |
| 18457324-11#105#121#diseaseC0278704 | 2224-2240 | diseaseC0278704 | denotes | childhood cancer |
| 20#25#geners105689295#98#diseaseC0018802 | 18457324-11#20#25#geners1056892 | 18457324-11#95#98#diseaseC0018802 | associated_with | V244M,CHF |
| 20#25#geners1056892105#121#diseaseC0278704 | 18457324-11#20#25#geners1056892 | 18457324-11#105#121#diseaseC0278704 | associated_with | V244M,childhood cancer |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 18457324-0#29#49#gene874 | 29-49 | gene874 | denotes | carbonyl reductase 3 |
| 18457324-0#55#59#gene874 | 55-59 | gene874 | denotes | CBR3 |
| 18457324-0#76#98#gene1429 | 76-98 | gene1429 | denotes | quinone oxidoreductase |
| 18457324-0#106#110#gene1728 | 106-110 | gene1728 | denotes | NQO1 |
| 18457324-0#159#183#diseaseC0018802 | 159-183 | diseaseC0018802 | denotes | congestive heart failure |
| 18457324-0#190#206#diseaseC0278704 | 190-206 | diseaseC0278704 | denotes | childhood cancer |
| 18457324-0#159#183#diseaseC0018802 | 159-183 | diseaseC0018802 | denotes | congestive heart failure |
| 18457324-0#190#206#diseaseC0278704 | 190-206 | diseaseC0278704 | denotes | childhood cancer |
| 18457324-0#159#183#diseaseC0018802 | 159-183 | diseaseC0018802 | denotes | congestive heart failure |
| 18457324-0#190#206#diseaseC0278704 | 190-206 | diseaseC0278704 | denotes | childhood cancer |
| 18457324-0#159#183#diseaseC0018802 | 159-183 | diseaseC0018802 | denotes | congestive heart failure |
| 18457324-0#190#206#diseaseC0278704 | 190-206 | diseaseC0278704 | denotes | childhood cancer |
| 29#49#gene874159#183#diseaseC0018802 | 18457324-0#29#49#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | carbonyl reductase 3,congestive heart failure |
| 29#49#gene874190#206#diseaseC0278704 | 18457324-0#29#49#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | carbonyl reductase 3,childhood cancer |
| 29#49#gene874159#183#diseaseC0018802 | 18457324-0#29#49#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | carbonyl reductase 3,congestive heart failure |
| 29#49#gene874190#206#diseaseC0278704 | 18457324-0#29#49#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | carbonyl reductase 3,childhood cancer |
| 29#49#gene874159#183#diseaseC0018802 | 18457324-0#29#49#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | carbonyl reductase 3,congestive heart failure |
| 29#49#gene874190#206#diseaseC0278704 | 18457324-0#29#49#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | carbonyl reductase 3,childhood cancer |
| 29#49#gene874159#183#diseaseC0018802 | 18457324-0#29#49#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | carbonyl reductase 3,congestive heart failure |
| 29#49#gene874190#206#diseaseC0278704 | 18457324-0#29#49#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | carbonyl reductase 3,childhood cancer |
| 55#59#gene874159#183#diseaseC0018802 | 18457324-0#55#59#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | CBR3,congestive heart failure |
| 55#59#gene874190#206#diseaseC0278704 | 18457324-0#55#59#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | CBR3,childhood cancer |
| 55#59#gene874159#183#diseaseC0018802 | 18457324-0#55#59#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | CBR3,congestive heart failure |
| 55#59#gene874190#206#diseaseC0278704 | 18457324-0#55#59#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | CBR3,childhood cancer |
| 55#59#gene874159#183#diseaseC0018802 | 18457324-0#55#59#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | CBR3,congestive heart failure |
| 55#59#gene874190#206#diseaseC0278704 | 18457324-0#55#59#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | CBR3,childhood cancer |
| 55#59#gene874159#183#diseaseC0018802 | 18457324-0#55#59#gene874 | 18457324-0#159#183#diseaseC0018802 | associated_with | CBR3,congestive heart failure |
| 55#59#gene874190#206#diseaseC0278704 | 18457324-0#55#59#gene874 | 18457324-0#190#206#diseaseC0278704 | associated_with | CBR3,childhood cancer |
| 76#98#gene1429159#183#diseaseC0018802 | 18457324-0#76#98#gene1429 | 18457324-0#159#183#diseaseC0018802 | associated_with | quinone oxidoreductase,congestive heart failure |
| 76#98#gene1429190#206#diseaseC0278704 | 18457324-0#76#98#gene1429 | 18457324-0#190#206#diseaseC0278704 | associated_with | quinone oxidoreductase,childhood cancer |
| 76#98#gene1429159#183#diseaseC0018802 | 18457324-0#76#98#gene1429 | 18457324-0#159#183#diseaseC0018802 | associated_with | quinone oxidoreductase,congestive heart failure |
| 76#98#gene1429190#206#diseaseC0278704 | 18457324-0#76#98#gene1429 | 18457324-0#190#206#diseaseC0278704 | associated_with | quinone oxidoreductase,childhood cancer |
| 76#98#gene1429159#183#diseaseC0018802 | 18457324-0#76#98#gene1429 | 18457324-0#159#183#diseaseC0018802 | associated_with | quinone oxidoreductase,congestive heart failure |
| 76#98#gene1429190#206#diseaseC0278704 | 18457324-0#76#98#gene1429 | 18457324-0#190#206#diseaseC0278704 | associated_with | quinone oxidoreductase,childhood cancer |
| 76#98#gene1429159#183#diseaseC0018802 | 18457324-0#76#98#gene1429 | 18457324-0#159#183#diseaseC0018802 | associated_with | quinone oxidoreductase,congestive heart failure |
| 76#98#gene1429190#206#diseaseC0278704 | 18457324-0#76#98#gene1429 | 18457324-0#190#206#diseaseC0278704 | associated_with | quinone oxidoreductase,childhood cancer |
| 106#110#gene1728159#183#diseaseC0018802 | 18457324-0#106#110#gene1728 | 18457324-0#159#183#diseaseC0018802 | associated_with | NQO1,congestive heart failure |
| 106#110#gene1728190#206#diseaseC0278704 | 18457324-0#106#110#gene1728 | 18457324-0#190#206#diseaseC0278704 | associated_with | NQO1,childhood cancer |
| 106#110#gene1728159#183#diseaseC0018802 | 18457324-0#106#110#gene1728 | 18457324-0#159#183#diseaseC0018802 | associated_with | NQO1,congestive heart failure |
| 106#110#gene1728190#206#diseaseC0278704 | 18457324-0#106#110#gene1728 | 18457324-0#190#206#diseaseC0278704 | associated_with | NQO1,childhood cancer |
| 106#110#gene1728159#183#diseaseC0018802 | 18457324-0#106#110#gene1728 | 18457324-0#159#183#diseaseC0018802 | associated_with | NQO1,congestive heart failure |
| 106#110#gene1728190#206#diseaseC0278704 | 18457324-0#106#110#gene1728 | 18457324-0#190#206#diseaseC0278704 | associated_with | NQO1,childhood cancer |
| 106#110#gene1728159#183#diseaseC0018802 | 18457324-0#106#110#gene1728 | 18457324-0#159#183#diseaseC0018802 | associated_with | NQO1,congestive heart failure |
| 106#110#gene1728190#206#diseaseC0278704 | 18457324-0#106#110#gene1728 | 18457324-0#190#206#diseaseC0278704 | associated_with | NQO1,childhood cancer |
tmVarCorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1164-1169 | ProteinMutation:p|SUB|V|244|M | denotes | V244M |
| T2 | 1356-1361 | ProteinMutation:p|SUB|V|244|M | denotes | V244M |
| T3 | 1551-1556 | ProteinMutation:p|SUB|V|244|M | denotes | V244M |
| T4 | 1776-1781 | ProteinMutation:p|SUB|V|244|M | denotes | V244M |
| T5 | 2139-2144 | ProteinMutation:p|SUB|V|244|M | denotes | V244M |