PubMed:18439803 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/18439803","sourcedb":"PubMed","sourceid":"18439803","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/18439803","text":"Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats.\nThe present study aimed to investigate the anticonvulsant activity as well as the effects on the level of hippocampal amino acid neurotransmitters (glutamate, aspartate, glycine and GABA) of N-(2-propylpentanoyl)urea (VPU) in comparison to its parent compound, valproic acid (VPA). VPU was more potent than VPA, exhibiting the median effective dose (ED(50)) of 49 mg/kg in protecting rats against pilocarpine-induced seizure whereas the corresponding value for VPA was 322 mg/kg. In vivo microdialysis demonstrated that an intraperitoneal administration of pilocarpine induced a pronounced increment of hippocampal glutamate and aspartate whereas no significant change was observed on the level of glycine and GABA. Pretreatment with either VPU (50 and 100 mg/kg) or VPA (300 and 600 mg/kg) completely abolished pilocarpine-evoked increases in extracellular glutamate and aspartate. In addition, a statistically significant reduction was also observed on the level of GABA and glycine but less than a drastic reduction of glutamate and aspartate level. Based on the finding that VPU and VPA could protect the animals against pilocarpine-induced seizure it is suggested that the reduction of inhibitory amino acid neurotransmitters was comparatively minor and offset by a pronounced reduction of glutamate and aspartate. Therefore, like VPA, the finding that VPU could drastically reduce pilocarpine-induced increases in glutamate and aspartate should account, at least partly, for its anticonvulsant activity observed in pilocarpine-induced seizure in experimental animals. Some other mechanism than those being reported herein should be further investigated.","tracks":[{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":121,"end":125},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":511,"end":515},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:10118"},{"id":"A2","pred":"db_id","subj":"T1","obj":"NCBItxid:10116"},{"id":"A3","pred":"db_id","subj":"T1","obj":"NCBItxid:10114"},{"id":"A4","pred":"db_id","subj":"T4","obj":"NCBItxid:10118"},{"id":"A5","pred":"db_id","subj":"T4","obj":"NCBItxid:10116"},{"id":"A6","pred":"db_id","subj":"T4","obj":"NCBItxid:10114"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T4","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":126},"obj":"Sentence"},{"id":"T2","span":{"begin":127,"end":408},"obj":"Sentence"},{"id":"T3","span":{"begin":409,"end":606},"obj":"Sentence"},{"id":"T4","span":{"begin":607,"end":842},"obj":"Sentence"},{"id":"T5","span":{"begin":843,"end":1009},"obj":"Sentence"},{"id":"T6","span":{"begin":1010,"end":1179},"obj":"Sentence"},{"id":"T7","span":{"begin":1180,"end":1446},"obj":"Sentence"},{"id":"T8","span":{"begin":1447,"end":1700},"obj":"Sentence"},{"id":"T9","span":{"begin":1701,"end":1786},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities","denotations":[{"id":"4964","span":{"begin":17,"end":42},"obj":"ChemicalEntity"},{"id":"4965","span":{"begin":90,"end":101},"obj":"ChemicalEntity"},{"id":"4966","span":{"begin":110,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"4967","span":{"begin":121,"end":125},"obj":"OrganismTaxon"},{"id":"4968","span":{"begin":275,"end":284},"obj":"ChemicalEntity"},{"id":"4969","span":{"begin":286,"end":295},"obj":"ChemicalEntity"},{"id":"4970","span":{"begin":297,"end":304},"obj":"ChemicalEntity"},{"id":"4971","span":{"begin":309,"end":313},"obj":"ChemicalEntity"},{"id":"4972","span":{"begin":318,"end":343},"obj":"ChemicalEntity"},{"id":"4973","span":{"begin":345,"end":348},"obj":"ChemicalEntity"},{"id":"4974","span":{"begin":388,"end":401},"obj":"ChemicalEntity"},{"id":"4975","span":{"begin":403,"end":406},"obj":"ChemicalEntity"},{"id":"4976","span":{"begin":409,"end":412},"obj":"ChemicalEntity"},{"id":"4977","span":{"begin":434,"end":437},"obj":"ChemicalEntity"},{"id":"4978","span":{"begin":511,"end":515},"obj":"OrganismTaxon"},{"id":"4979","span":{"begin":524,"end":535},"obj":"ChemicalEntity"},{"id":"4980","span":{"begin":544,"end":551},"obj":"DiseaseOrPhenotypicFeature"},{"id":"4981","span":{"begin":588,"end":591},"obj":"ChemicalEntity"},{"id":"4982","span":{"begin":684,"end":695},"obj":"ChemicalEntity"},{"id":"4983","span":{"begin":742,"end":751},"obj":"ChemicalEntity"},{"id":"4984","span":{"begin":756,"end":765},"obj":"ChemicalEntity"},{"id":"4985","span":{"begin":825,"end":832},"obj":"ChemicalEntity"},{"id":"4986","span":{"begin":837,"end":841},"obj":"ChemicalEntity"},{"id":"4987","span":{"begin":868,"end":871},"obj":"ChemicalEntity"},{"id":"4988","span":{"begin":894,"end":897},"obj":"ChemicalEntity"},{"id":"4989","span":{"begin":939,"end":950},"obj":"ChemicalEntity"},{"id":"4990","span":{"begin":985,"end":994},"obj":"ChemicalEntity"},{"id":"4991","span":{"begin":999,"end":1008},"obj":"ChemicalEntity"},{"id":"4992","span":{"begin":1095,"end":1099},"obj":"ChemicalEntity"},{"id":"4993","span":{"begin":1104,"end":1111},"obj":"ChemicalEntity"},{"id":"4994","span":{"begin":1149,"end":1158},"obj":"ChemicalEntity"},{"id":"4995","span":{"begin":1163,"end":1172},"obj":"ChemicalEntity"},{"id":"4996","span":{"begin":1206,"end":1209},"obj":"ChemicalEntity"},{"id":"4997","span":{"begin":1214,"end":1217},"obj":"ChemicalEntity"},{"id":"4998","span":{"begin":1252,"end":1263},"obj":"ChemicalEntity"},{"id":"4999","span":{"begin":1272,"end":1279},"obj":"DiseaseOrPhenotypicFeature"},{"id":"5000","span":{"begin":1422,"end":1431},"obj":"ChemicalEntity"},{"id":"5001","span":{"begin":1436,"end":1445},"obj":"ChemicalEntity"},{"id":"5002","span":{"begin":1463,"end":1466},"obj":"ChemicalEntity"},{"id":"5003","span":{"begin":1485,"end":1488},"obj":"ChemicalEntity"},{"id":"5004","span":{"begin":1514,"end":1525},"obj":"ChemicalEntity"},{"id":"5005","span":{"begin":1547,"end":1556},"obj":"ChemicalEntity"},{"id":"5006","span":{"begin":1561,"end":1570},"obj":"ChemicalEntity"},{"id":"5007","span":{"begin":1648,"end":1659},"obj":"ChemicalEntity"},{"id":"5008","span":{"begin":1668,"end":1675},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A35","pred":"db_id","subj":"4998","obj":"MESH:D010862"},{"id":"A1","pred":"db_id","subj":"4964","obj":"MESH:C108761"},{"id":"A29","pred":"db_id","subj":"4992","obj":"MESH:D005680"},{"id":"A18","pred":"db_id","subj":"4981","obj":"MESH:D014635"},{"id":"A26","pred":"db_id","subj":"4989","obj":"MESH:D010862"},{"id":"A44","pred":"db_id","subj":"5007","obj":"MESH:D010862"},{"id":"A7","pred":"db_id","subj":"4970","obj":"MESH:D005998"},{"id":"A16","pred":"db_id","subj":"4979","obj":"MESH:D010862"},{"id":"A6","pred":"db_id","subj":"4969","obj":"MESH:D001224"},{"id":"A9","pred":"db_id","subj":"4972","obj":"MESH:C108761"},{"id":"A33","pred":"db_id","subj":"4996","obj":"MESH:C108761"},{"id":"A14","pred":"db_id","subj":"4977","obj":"MESH:D014635"},{"id":"A2","pred":"db_id","subj":"4965","obj":"MESH:D010862"},{"id":"A11","pred":"db_id","subj":"4974","obj":"MESH:D014635"},{"id":"A36","pred":"db_id","subj":"4999","obj":"MESH:D012640"},{"id":"A30","pred":"db_id","subj":"4993","obj":"MESH:D005998"},{"id":"A38","pred":"db_id","subj":"5001","obj":"MESH:D001224"},{"id":"A39","pred":"db_id","subj":"5002","obj":"MESH:D014635"},{"id":"A19","pred":"db_id","subj":"4982","obj":"MESH:D010862"},{"id":"A23","pred":"db_id","subj":"4986","obj":"MESH:D005680"},{"id":"A15","pred":"db_id","subj":"4978","obj":"NCBITaxon:10116"},{"id":"A5","pred":"db_id","subj":"4968","obj":"MESH:D018698"},{"id":"A20","pred":"db_id","subj":"4983","obj":"MESH:D018698"},{"id":"A34","pred":"db_id","subj":"4997","obj":"MESH:D014635"},{"id":"A28","pred":"db_id","subj":"4991","obj":"MESH:D001224"},{"id":"A21","pred":"db_id","subj":"4984","obj":"MESH:D001224"},{"id":"A25","pred":"db_id","subj":"4988","obj":"MESH:D014635"},{"id":"A43","pred":"db_id","subj":"5006","obj":"MESH:D001224"},{"id":"A31","pred":"db_id","subj":"4994","obj":"MESH:D018698"},{"id":"A3","pred":"db_id","subj":"4966","obj":"MESH:D012640"},{"id":"A24","pred":"db_id","subj":"4987","obj":"MESH:C108761"},{"id":"A45","pred":"db_id","subj":"5008","obj":"MESH:D012640"},{"id":"A4","pred":"db_id","subj":"4967","obj":"NCBITaxon:10116"},{"id":"A8","pred":"db_id","subj":"4971","obj":"MESH:D005680"},{"id":"A12","pred":"db_id","subj":"4975","obj":"MESH:D014635"},{"id":"A27","pred":"db_id","subj":"4990","obj":"MESH:D018698"},{"id":"A41","pred":"db_id","subj":"5004","obj":"MESH:D010862"},{"id":"A17","pred":"db_id","subj":"4980","obj":"MESH:D012640"},{"id":"A37","pred":"db_id","subj":"5000","obj":"MESH:D018698"},{"id":"A13","pred":"db_id","subj":"4976","obj":"MESH:C108761"},{"id":"A42","pred":"db_id","subj":"5005","obj":"MESH:D018698"},{"id":"A22","pred":"db_id","subj":"4985","obj":"MESH:D005998"},{"id":"A32","pred":"db_id","subj":"4995","obj":"MESH:D001224"},{"id":"A40","pred":"db_id","subj":"5003","obj":"MESH:C108761"},{"id":"A10","pred":"db_id","subj":"4973","obj":"MESH:C108761"},{"subj":"4964","pred":"source","obj":"LitCoin-entities"},{"subj":"4965","pred":"source","obj":"LitCoin-entities"},{"subj":"4966","pred":"source","obj":"LitCoin-entities"},{"subj":"4967","pred":"source","obj":"LitCoin-entities"},{"subj":"4968","pred":"source","obj":"LitCoin-entities"},{"subj":"4969","pred":"source","obj":"LitCoin-entities"},{"subj":"4970","pred":"source","obj":"LitCoin-entities"},{"subj":"4971","pred":"source","obj":"LitCoin-entities"},{"subj":"4972","pred":"source","obj":"LitCoin-entities"},{"subj":"4973","pred":"source","obj":"LitCoin-entities"},{"subj":"4974","pred":"source","obj":"LitCoin-entities"},{"subj":"4975","pred":"source","obj":"LitCoin-entities"},{"subj":"4976","pred":"source","obj":"LitCoin-entities"},{"subj":"4977","pred":"source","obj":"LitCoin-entities"},{"subj":"4978","pred":"source","obj":"LitCoin-entities"},{"subj":"4979","pred":"source","obj":"LitCoin-entities"},{"subj":"4980","pred":"source","obj":"LitCoin-entities"},{"subj":"4981","pred":"source","obj":"LitCoin-entities"},{"subj":"4982","pred":"source","obj":"LitCoin-entities"},{"subj":"4983","pred":"source","obj":"LitCoin-entities"},{"subj":"4984","pred":"source","obj":"LitCoin-entities"},{"subj":"4985","pred":"source","obj":"LitCoin-entities"},{"subj":"4986","pred":"source","obj":"LitCoin-entities"},{"subj":"4987","pred":"source","obj":"LitCoin-entities"},{"subj":"4988","pred":"source","obj":"LitCoin-entities"},{"subj":"4989","pred":"source","obj":"LitCoin-entities"},{"subj":"4990","pred":"source","obj":"LitCoin-entities"},{"subj":"4991","pred":"source","obj":"LitCoin-entities"},{"subj":"4992","pred":"source","obj":"LitCoin-entities"},{"subj":"4993","pred":"source","obj":"LitCoin-entities"},{"subj":"4994","pred":"source","obj":"LitCoin-entities"},{"subj":"4995","pred":"source","obj":"LitCoin-entities"},{"subj":"4996","pred":"source","obj":"LitCoin-entities"},{"subj":"4997","pred":"source","obj":"LitCoin-entities"},{"subj":"4998","pred":"source","obj":"LitCoin-entities"},{"subj":"4999","pred":"source","obj":"LitCoin-entities"},{"subj":"5000","pred":"source","obj":"LitCoin-entities"},{"subj":"5001","pred":"source","obj":"LitCoin-entities"},{"subj":"5002","pred":"source","obj":"LitCoin-entities"},{"subj":"5003","pred":"source","obj":"LitCoin-entities"},{"subj":"5004","pred":"source","obj":"LitCoin-entities"},{"subj":"5005","pred":"source","obj":"LitCoin-entities"},{"subj":"5006","pred":"source","obj":"LitCoin-entities"},{"subj":"5007","pred":"source","obj":"LitCoin-entities"},{"subj":"5008","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":918,"end":928},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0700063"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":58,"end":68},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":110,"end":117},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":245,"end":255},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":275,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":286,"end":295},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":309,"end":313},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":397,"end":401},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":544,"end":551},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":742,"end":751},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":756,"end":765},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":837,"end":841},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":971,"end":984},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":985,"end":994},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":999,"end":1008},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":1095,"end":1099},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":1149,"end":1158},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1163,"end":1172},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1272,"end":1279},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1329,"end":1339},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1376,"end":1381},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1422,"end":1431},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1436,"end":1445},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1458,"end":1462},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1547,"end":1556},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1561,"end":1570},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1668,"end":1675},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1706,"end":1711},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":38,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":58,"end":68},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":102,"end":109},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":110,"end":117},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":185,"end":193},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":245,"end":255},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":275,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":286,"end":295},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":309,"end":313},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":339,"end":343},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":397,"end":401},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":491,"end":493},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":536,"end":543},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":544,"end":551},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":578,"end":583},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":600,"end":602},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":696,"end":703},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":742,"end":751},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":756,"end":765},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":837,"end":841},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":884,"end":886},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":911,"end":913},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":971,"end":984},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":985,"end":994},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":999,"end":1008},"obj":"GeneOrGeneProduct"},{"id":"T26","span":{"begin":1095,"end":1099},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":1149,"end":1158},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":1163,"end":1172},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":1180,"end":1185},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":1193,"end":1200},"obj":"GeneOrGeneProduct"},{"id":"T31","span":{"begin":1264,"end":1271},"obj":"GeneOrGeneProduct"},{"id":"T32","span":{"begin":1272,"end":1279},"obj":"GeneOrGeneProduct"},{"id":"T33","span":{"begin":1329,"end":1339},"obj":"GeneOrGeneProduct"},{"id":"T34","span":{"begin":1376,"end":1381},"obj":"GeneOrGeneProduct"},{"id":"T35","span":{"begin":1422,"end":1431},"obj":"GeneOrGeneProduct"},{"id":"T36","span":{"begin":1436,"end":1445},"obj":"GeneOrGeneProduct"},{"id":"T37","span":{"begin":1458,"end":1462},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":1472,"end":1479},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":1507,"end":1513},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":1526,"end":1533},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":1547,"end":1556},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":1561,"end":1570},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":1596,"end":1602},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":1627,"end":1635},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":1660,"end":1667},"obj":"GeneOrGeneProduct"},{"id":"T46","span":{"begin":1668,"end":1675},"obj":"GeneOrGeneProduct"},{"id":"T47","span":{"begin":1706,"end":1711},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T26","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T27","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T28","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T29","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T30","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T31","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T32","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T33","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T34","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T35","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T36","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T37","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T38","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T39","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T40","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T41","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T42","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T43","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T44","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T45","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T46","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T47","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":110,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":544,"end":551},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1272,"end":1279},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1668,"end":1675},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D012640"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D012640"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D012640"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D012640"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":275,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":742,"end":751},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":985,"end":994},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":1149,"end":1158},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1422,"end":1431},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":1547,"end":1556},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":121,"end":125},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":511,"end":515},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":110,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":544,"end":551},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1272,"end":1279},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1668,"end":1675},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D012640"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D012640"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D012640"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D012640"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":110,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":544,"end":551},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1272,"end":1279},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1668,"end":1675},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D012640"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012640"},{"id":"A3","pred":"#label","subj":"T3","obj":"D012640"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012640"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":17,"end":42},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":69,"end":86},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":90,"end":101},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":256,"end":273},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":275,"end":284},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":286,"end":295},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":297,"end":304},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":309,"end":313},"obj":"ChemicalEntity"},{"id":"T16","span":{"begin":318,"end":343},"obj":"ChemicalEntity"},{"id":"T18","span":{"begin":345,"end":348},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":388,"end":401},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":403,"end":406},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":409,"end":412},"obj":"ChemicalEntity"},{"id":"T24","span":{"begin":434,"end":437},"obj":"ChemicalEntity"},{"id":"T26","span":{"begin":524,"end":535},"obj":"ChemicalEntity"},{"id":"T28","span":{"begin":588,"end":591},"obj":"ChemicalEntity"},{"id":"T30","span":{"begin":684,"end":695},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":742,"end":751},"obj":"ChemicalEntity"},{"id":"T34","span":{"begin":756,"end":765},"obj":"ChemicalEntity"},{"id":"T37","span":{"begin":825,"end":832},"obj":"ChemicalEntity"},{"id":"T40","span":{"begin":837,"end":841},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":868,"end":871},"obj":"ChemicalEntity"},{"id":"T42","span":{"begin":894,"end":897},"obj":"ChemicalEntity"},{"id":"T44","span":{"begin":939,"end":950},"obj":"ChemicalEntity"},{"id":"T46","span":{"begin":985,"end":994},"obj":"ChemicalEntity"},{"id":"T48","span":{"begin":999,"end":1008},"obj":"ChemicalEntity"},{"id":"T51","span":{"begin":1095,"end":1099},"obj":"ChemicalEntity"},{"id":"T52","span":{"begin":1104,"end":1111},"obj":"ChemicalEntity"},{"id":"T55","span":{"begin":1149,"end":1158},"obj":"ChemicalEntity"},{"id":"T57","span":{"begin":1163,"end":1172},"obj":"ChemicalEntity"},{"id":"T60","span":{"begin":1206,"end":1209},"obj":"ChemicalEntity"},{"id":"T61","span":{"begin":1214,"end":1217},"obj":"ChemicalEntity"},{"id":"T63","span":{"begin":1252,"end":1263},"obj":"ChemicalEntity"},{"id":"T65","span":{"begin":1340,"end":1357},"obj":"ChemicalEntity"},{"id":"T66","span":{"begin":1422,"end":1431},"obj":"ChemicalEntity"},{"id":"T68","span":{"begin":1436,"end":1445},"obj":"ChemicalEntity"},{"id":"T71","span":{"begin":1463,"end":1466},"obj":"ChemicalEntity"},{"id":"T73","span":{"begin":1485,"end":1488},"obj":"ChemicalEntity"},{"id":"T74","span":{"begin":1514,"end":1525},"obj":"ChemicalEntity"},{"id":"T76","span":{"begin":1547,"end":1556},"obj":"ChemicalEntity"},{"id":"T78","span":{"begin":1561,"end":1570},"obj":"ChemicalEntity"},{"id":"T81","span":{"begin":1648,"end":1659},"obj":"ChemicalEntity"}],"attributes":[{"id":"A9","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A11","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A32","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A33","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A78","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A79","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A80","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A3","pred":"ID:","subj":"T3","obj":"ChemicalEntity"},{"id":"A46","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A47","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A48","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A49","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A50","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A61","pred":"ID:","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A62","pred":"ID:","subj":"T61","obj":"D014635"},{"id":"A60","pred":"ID:","subj":"T60","obj":"ChemicalEntity"},{"id":"A30","pred":"ID:","subj":"T30","obj":"D010862"},{"id":"A31","pred":"ID:","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A18","pred":"ID:","subj":"T18","obj":"ChemicalEntity"},{"id":"A24","pred":"ID:","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A25","pred":"ID:","subj":"T24","obj":"D014635"},{"id":"A73","pred":"ID:","subj":"T73","obj":"ChemicalEntity"},{"id":"A21","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A22","pred":"ID:","subj":"T21","obj":"D014635"},{"id":"A23","pred":"ID:","subj":"T23","obj":"ChemicalEntity"},{"id":"A68","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A69","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A70","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A44","pred":"ID:","subj":"T44","obj":"D010862"},{"id":"A45","pred":"ID:","subj":"T44","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A55","pred":"ID:","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A56","pred":"ID:","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A66","pred":"ID:","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A67","pred":"ID:","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A81","pred":"ID:","subj":"T81","obj":"D010862"},{"id":"A82","pred":"ID:","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D010862"},{"id":"A5","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A13","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A14","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A41","pred":"ID:","subj":"T41","obj":"ChemicalEntity"},{"id":"A42","pred":"ID:","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A43","pred":"ID:","subj":"T42","obj":"D014635"},{"id":"A51","pred":"ID:","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A52","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A53","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A54","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A57","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A58","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A59","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D014635"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A76","pred":"ID:","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A77","pred":"ID:","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A6","pred":"ID:","subj":"T6","obj":"ChemicalEntity"},{"id":"A15","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A26","pred":"ID:","subj":"T26","obj":"D010862"},{"id":"A27","pred":"ID:","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A37","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A38","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A39","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A1","pred":"ID:","subj":"T1","obj":"C108761"},{"id":"A2","pred":"ID:","subj":"T1","obj":"ChemicalEntity"},{"id":"A34","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A35","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A36","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A40","pred":"ID:","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A28","pred":"ID:","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A29","pred":"ID:","subj":"T28","obj":"D014635"},{"id":"A63","pred":"ID:","subj":"T63","obj":"D010862"},{"id":"A64","pred":"ID:","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A16","pred":"ID:","subj":"T16","obj":"C108761"},{"id":"A17","pred":"ID:","subj":"T16","obj":"ChemicalEntity"},{"id":"A74","pred":"ID:","subj":"T74","obj":"D010862"},{"id":"A75","pred":"ID:","subj":"T74","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A71","pred":"ID:","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A72","pred":"ID:","subj":"T71","obj":"D014635"},{"id":"A65","pred":"ID:","subj":"T65","obj":"ChemicalEntity"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T4","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T6","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T7","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T9","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T12","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T15","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T16","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T18","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T19","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T21","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T23","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T24","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T26","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T28","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T30","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T32","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T34","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T37","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T40","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T41","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T42","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T44","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T46","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T48","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T52","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T55","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T57","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T60","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T61","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T63","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T65","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T66","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T68","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T71","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T73","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T74","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T76","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T78","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T81","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T81","span":{"begin":1648,"end":1659},"obj":"ChemicalEntity"},{"id":"T78","span":{"begin":1561,"end":1570},"obj":"ChemicalEntity"},{"id":"T76","span":{"begin":1547,"end":1556},"obj":"ChemicalEntity"},{"id":"T74","span":{"begin":1514,"end":1525},"obj":"ChemicalEntity"},{"id":"T73","span":{"begin":1485,"end":1488},"obj":"ChemicalEntity"},{"id":"T71","span":{"begin":1463,"end":1466},"obj":"ChemicalEntity"},{"id":"T68","span":{"begin":1436,"end":1445},"obj":"ChemicalEntity"},{"id":"T66","span":{"begin":1422,"end":1431},"obj":"ChemicalEntity"},{"id":"T65","span":{"begin":1340,"end":1357},"obj":"ChemicalEntity"},{"id":"T63","span":{"begin":1252,"end":1263},"obj":"ChemicalEntity"},{"id":"T61","span":{"begin":1214,"end":1217},"obj":"ChemicalEntity"},{"id":"T60","span":{"begin":1206,"end":1209},"obj":"ChemicalEntity"},{"id":"T57","span":{"begin":1163,"end":1172},"obj":"ChemicalEntity"},{"id":"T55","span":{"begin":1149,"end":1158},"obj":"ChemicalEntity"},{"id":"T52","span":{"begin":1104,"end":1111},"obj":"ChemicalEntity"},{"id":"T51","span":{"begin":1095,"end":1099},"obj":"ChemicalEntity"},{"id":"T48","span":{"begin":999,"end":1008},"obj":"ChemicalEntity"},{"id":"T46","span":{"begin":985,"end":994},"obj":"ChemicalEntity"},{"id":"T44","span":{"begin":939,"end":950},"obj":"ChemicalEntity"},{"id":"T42","span":{"begin":894,"end":897},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":868,"end":871},"obj":"ChemicalEntity"},{"id":"T40","span":{"begin":837,"end":841},"obj":"ChemicalEntity"},{"id":"T37","span":{"begin":825,"end":832},"obj":"ChemicalEntity"},{"id":"T34","span":{"begin":756,"end":765},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":742,"end":751},"obj":"ChemicalEntity"},{"id":"T30","span":{"begin":684,"end":695},"obj":"ChemicalEntity"},{"id":"T28","span":{"begin":588,"end":591},"obj":"ChemicalEntity"},{"id":"T26","span":{"begin":524,"end":535},"obj":"ChemicalEntity"},{"id":"T24","span":{"begin":434,"end":437},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":409,"end":412},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":403,"end":406},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":388,"end":401},"obj":"ChemicalEntity"},{"id":"T18","span":{"begin":345,"end":348},"obj":"ChemicalEntity"},{"id":"T16","span":{"begin":318,"end":343},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":309,"end":313},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":297,"end":304},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":286,"end":295},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":275,"end":284},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":256,"end":273},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":90,"end":101},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":69,"end":86},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":17,"end":42},"obj":"ChemicalEntity"},{"id":"T55835","span":{"begin":1547,"end":1556},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1422,"end":1431},"obj":"GeneOrGeneProduct"},{"id":"T21509","span":{"begin":1149,"end":1158},"obj":"GeneOrGeneProduct"},{"id":"T58501","span":{"begin":985,"end":994},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":742,"end":751},"obj":"GeneOrGeneProduct"},{"id":"T23969","span":{"begin":275,"end":284},"obj":"GeneOrGeneProduct"},{"id":"T55089","span":{"begin":1668,"end":1675},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T52311","span":{"begin":1272,"end":1279},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T29449","span":{"begin":544,"end":551},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T41848","span":{"begin":110,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T35093","span":{"begin":511,"end":515},"obj":"OrganismTaxon"},{"id":"T87767","span":{"begin":121,"end":125},"obj":"OrganismTaxon"}],"attributes":[{"id":"A3","pred":"ID:","subj":"T3","obj":"ChemicalEntity"},{"id":"A5","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D010862"},{"id":"A80","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A79","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A78","pred":"ID:","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A15","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A73","pred":"ID:","subj":"T73","obj":"ChemicalEntity"},{"id":"A64","pred":"ID:","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A63","pred":"ID:","subj":"T63","obj":"D010862"},{"id":"A17","pred":"ID:","subj":"T16","obj":"ChemicalEntity"},{"id":"A16","pred":"ID:","subj":"T16","obj":"C108761"},{"id":"A54","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A53","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A52","pred":"ID:","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A67326","pred":"#label","subj":"T29449","obj":"D012640"},{"id":"A62","pred":"ID:","subj":"T61","obj":"D014635"},{"id":"A61","pred":"ID:","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A14","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A13","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A12","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A11","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A9","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A33","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A32","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A6","pred":"ID:","subj":"T6","obj":"ChemicalEntity"},{"id":"A16380","pred":"#label","subj":"T52311","obj":"D012640"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D014635"},{"id":"A2","pred":"ID:","subj":"T1","obj":"ChemicalEntity"},{"id":"A1","pred":"ID:","subj":"T1","obj":"C108761"},{"id":"A45","pred":"ID:","subj":"T44","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A44","pred":"ID:","subj":"T44","obj":"D010862"},{"id":"A43","pred":"ID:","subj":"T42","obj":"D014635"},{"id":"A42","pred":"ID:","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A36","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A35","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A34","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A18","pred":"ID:","subj":"T18","obj":"ChemicalEntity"},{"id":"A41","pred":"ID:","subj":"T41","obj":"ChemicalEntity"},{"id":"A72","pred":"ID:","subj":"T71","obj":"D014635"},{"id":"A71","pred":"ID:","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A52830","pred":"#label","subj":"T41848","obj":"D012640"},{"id":"A39","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A38","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_29947"},{"id":"A37","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_57305"},{"id":"A23","pred":"ID:","subj":"T23","obj":"ChemicalEntity"},{"id":"A76620","pred":"#label","subj":"T55089","obj":"D012640"},{"id":"A60","pred":"ID:","subj":"T60","obj":"ChemicalEntity"},{"id":"A27","pred":"ID:","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A26","pred":"ID:","subj":"T26","obj":"D010862"},{"id":"A56","pred":"ID:","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A55","pred":"ID:","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A22","pred":"ID:","subj":"T21","obj":"D014635"},{"id":"A21","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A70","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A69","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A68","pred":"ID:","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A59","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A58","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A57","pred":"ID:","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A31","pred":"ID:","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A30","pred":"ID:","subj":"T30","obj":"D010862"},{"id":"A51","pred":"ID:","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A75","pred":"ID:","subj":"T74","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A74","pred":"ID:","subj":"T74","obj":"D010862"},{"id":"A82","pred":"ID:","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_39462"},{"id":"A81","pred":"ID:","subj":"T81","obj":"D010862"},{"id":"A77","pred":"ID:","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A76","pred":"ID:","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A29","pred":"ID:","subj":"T28","obj":"D014635"},{"id":"A28","pred":"ID:","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A49","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A48","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A50","pred":"ID:","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A65","pred":"ID:","subj":"T65","obj":"ChemicalEntity"},{"id":"A25","pred":"ID:","subj":"T24","obj":"D014635"},{"id":"A24","pred":"ID:","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_39867"},{"id":"A67","pred":"ID:","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A66","pred":"ID:","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A47","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_14321"},{"id":"A46","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_29987"},{"id":"A40","pred":"ID:","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"subj":"T81","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T78","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T76","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T74","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T73","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T71","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T68","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T66","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T65","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T63","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T61","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T60","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T57","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T55","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T52","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T51","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T48","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T46","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T44","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T42","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T41","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T40","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T37","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T34","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T32","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T30","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T28","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T26","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T24","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T23","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T21","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T19","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T18","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T12","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T55835","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T21509","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T58501","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T23969","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T55089","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T52311","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T29449","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T41848","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T35093","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T87767","pred":"source","obj":"LitCoin-training-merged"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#93eaec","default":true},{"id":"LitCoin-sentences","color":"#ecd393"},{"id":"LitCoin-entities","color":"#b993ec"},{"id":"LitCoin_Mondo","color":"#93ec9f"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#ec93a0"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#93baec"},{"id":"LitCoin-Disease-MeSH","color":"#d4ec93"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#ea93ec"},{"id":"LitCoin-NCBITaxon-2","color":"#93ecd0"},{"id":"LitCoin-MeSH-Disease-2","color":"#ecb693"},{"id":"LitCoin-MONDO_bioort2019","color":"#9b93ec"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#a4ec93"},{"id":"LitCoin-training-merged","color":"#ec93be"}]}]}}