PubMed:18310445
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 170-179 | DiseaseOrPhenotypicFeature | denotes | pituitary | 0021156 |
| T2 | 979-988 | DiseaseOrPhenotypicFeature | denotes | pituitary | 0021156 |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 156-161 | OrganismTaxon | denotes | sheep | NCBItxid:9940 |
| T2 | 289-294 | OrganismTaxon | denotes | mouse | NCBItxid:10090|NCBItxid:10088 |
| T4 | 973-978 | OrganismTaxon | denotes | sheep | NCBItxid:9940 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-121 | Sentence | denotes | Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LbetaT2 gonadotrophs. |
| T2 | 122-272 | Sentence | denotes | We have shown previously that, in sheep primary pituitary cells, bone morphogenetic proteins (BMP)-4 inhibits FSHbeta mRNA expression and FSH release. |
| T3 | 273-433 | Sentence | denotes | In contrast, in mouse LbetaT2 gonadotrophs, others have shown a stimulatory effect of BMPs on basal or activin-stimulated FSHbeta promoter-driven transcription. |
| T4 | 434-609 | Sentence | denotes | As a species comparison with our previous results, we used LbetaT2 cells to investigate the effects of BMP-4 on gonadotrophin mRNA and secretion modulated by activin and GnRH. |
| T5 | 610-779 | Sentence | denotes | BMP-4 alone had no effect on FSH production, but enhanced the activin+GnRH-induced stimulation of FSHbeta mRNA and FSH secretion, without any effect on follistatin mRNA. |
| T6 | 780-957 | Sentence | denotes | BMP-4 reduced LHbeta mRNA up-regulation in response to GnRH (+/-activin) and decreased GnRH receptor expression, which would favour FSH, rather than LH, synthesis and secretion. |
| T7 | 958-1104 | Sentence | denotes | In contrast to sheep pituitary gonadotrophs, which express only BMP receptor types IA (BMPRIA) and II (BMPRII), LbetaT2 cells also express BMPRIB. |
| T8 | 1105-1262 | Sentence | denotes | Smad1/5 phosphorylation induced by BMP-4, indicating activation of BMP signalling, was the same whether BMP-4 was used alone or combined with activin+/-GnRH. |
| T9 | 1263-1493 | Sentence | denotes | We hypothesized that activin and/or GnRH pathways may be modulated by BMP-4, but neither the activin-stimulated phosphorylation of Smad2/3 nor the GnRH-induced ERK1/2 or cAMP response element-binding phosphorylation were modified. |
| T10 | 1494-1566 | Sentence | denotes | However, the GnRH-induced activation of p38 MAPK was decreased by BMP-4. |
| T11 | 1567-1674 | Sentence | denotes | This was associated with increased FSHbeta mRNA levels and FSH secretion, but decreased LHbeta mRNA levels. |
| T12 | 1675-1699 | Sentence | denotes | These results confirm 1. |
| T13 | 1700-1931 | Sentence | denotes | BMPs as important modulators of activin and/or GnRH-stimulated gonadotrophin synthesis and release and 2. important species differences in these effects, which could relate to differences in BMP receptor expression in gonadotrophs. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 4753 | 0-28 | GeneOrGeneProduct | denotes | Bone morphogenetic protein-4 | NCBIGene:652 |
| 4754 | 44-51 | GeneOrGeneProduct | denotes | activin | NCBIGene:3624|NCBIGene:83729 |
| 4755 | 56-60 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4756 | 73-86 | GeneOrGeneProduct | denotes | gonadotrophin | NCBIGene:12640|NCBIGene:14308 |
| 4757 | 100-107 | CellLine | denotes | LbetaT2 | NCBITaxon:10090 |
| 4758 | 156-161 | OrganismTaxon | denotes | sheep | NCBITaxon:9940 |
| 4759 | 187-222 | GeneOrGeneProduct | denotes | bone morphogenetic proteins (BMP)-4 | NCBIGene:443502 |
| 4760 | 232-239 | GeneOrGeneProduct | denotes | FSHbeta | NCBIGene:443387 |
| 4761 | 260-263 | GeneOrGeneProduct | denotes | FSH | NCBIGene:443387|NCBIGene:443538 |
| 4762 | 289-294 | OrganismTaxon | denotes | mouse | NCBITaxon:10090 |
| 4763 | 295-302 | CellLine | denotes | LbetaT2 | NCBITaxon:10090 |
| 4764 | 359-363 | GeneOrGeneProduct | denotes | BMPs | NCBIGene:652 |
| 4765 | 376-383 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4766 | 395-402 | GeneOrGeneProduct | denotes | FSHbeta | NCBIGene:14308 |
| 4767 | 493-500 | CellLine | denotes | LbetaT2 | NCBITaxon:10090 |
| 4768 | 537-542 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4769 | 546-559 | GeneOrGeneProduct | denotes | gonadotrophin | NCBIGene:12640|NCBIGene:14308 |
| 4770 | 592-599 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4771 | 604-608 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4772 | 610-615 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4773 | 639-642 | GeneOrGeneProduct | denotes | FSH | NCBIGene:443387|NCBIGene:443538 |
| 4774 | 672-679 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4775 | 680-684 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4776 | 708-715 | GeneOrGeneProduct | denotes | FSHbeta | NCBIGene:14308 |
| 4777 | 725-728 | GeneOrGeneProduct | denotes | FSH | NCBIGene:443387|NCBIGene:443538 |
| 4778 | 762-773 | GeneOrGeneProduct | denotes | follistatin | NCBIGene:14313 |
| 4779 | 780-785 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4780 | 794-800 | GeneOrGeneProduct | denotes | LHbeta | NCBIGene:16866 |
| 4781 | 835-839 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4782 | 844-851 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4783 | 867-880 | GeneOrGeneProduct | denotes | GnRH receptor | NCBIGene:14715 |
| 4784 | 912-915 | GeneOrGeneProduct | denotes | FSH | NCBIGene:443387|NCBIGene:443538 |
| 4785 | 929-931 | GeneOrGeneProduct | denotes | LH | NCBIGene:12640|NCBIGene:16866 |
| 4786 | 973-978 | OrganismTaxon | denotes | sheep | NCBITaxon:9940 |
| 4787 | 1022-1068 | GeneOrGeneProduct | denotes | BMP receptor types IA (BMPRIA) and II (BMPRII) | NCBIGene:101103793|NCBIGene:101112282 |
| 4788 | 1070-1077 | CellLine | denotes | LbetaT2 | NCBITaxon:10090 |
| 4789 | 1097-1103 | GeneOrGeneProduct | denotes | BMPRIB | NCBIGene:12167 |
| 4790 | 1105-1112 | GeneOrGeneProduct | denotes | Smad1/5 | NCBIGene:17125|NCBIGene:17129 |
| 4791 | 1140-1145 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4792 | 1172-1175 | GeneOrGeneProduct | denotes | BMP | NCBIGene:12159 |
| 4793 | 1209-1214 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4794 | 1247-1254 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4795 | 1257-1261 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4796 | 1284-1291 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4797 | 1299-1303 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4798 | 1333-1338 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4799 | 1356-1363 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4800 | 1394-1401 | GeneOrGeneProduct | denotes | Smad2/3 | NCBIGene:17126|NCBIGene:17127 |
| 4801 | 1410-1414 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4802 | 1423-1429 | GeneOrGeneProduct | denotes | ERK1/2 | NCBIGene:26413|NCBIGene:26417 |
| 4803 | 1433-1462 | GeneOrGeneProduct | denotes | cAMP response element-binding | NCBIGene:12912 |
| 4804 | 1507-1511 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4805 | 1534-1542 | GeneOrGeneProduct | denotes | p38 MAPK | NCBIGene:26416 |
| 4806 | 1560-1565 | GeneOrGeneProduct | denotes | BMP-4 | NCBIGene:652 |
| 4807 | 1602-1609 | GeneOrGeneProduct | denotes | FSHbeta | NCBIGene:14308 |
| 4808 | 1626-1629 | GeneOrGeneProduct | denotes | FSH | NCBIGene:443387|NCBIGene:443538 |
| 4809 | 1655-1661 | GeneOrGeneProduct | denotes | LHbeta | NCBIGene:16866 |
| 4810 | 1700-1704 | GeneOrGeneProduct | denotes | BMPs | NCBIGene:652 |
| 4811 | 1732-1739 | GeneOrGeneProduct | denotes | activin | NCBIGene:16323 |
| 4812 | 1747-1751 | GeneOrGeneProduct | denotes | GnRH | NCBIGene:14714 |
| 4813 | 1763-1776 | GeneOrGeneProduct | denotes | gonadotrophin | NCBIGene:12640|NCBIGene:14308 |
| 4814 | 1891-1903 | GeneOrGeneProduct | denotes | BMP receptor | NCBIGene:101103793|NCBIGene:101112282|NCBIGene:12167 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-26 | GeneOrGeneProduct | denotes | Bone morphogenetic protein |
| T2 | 44-51 | GeneOrGeneProduct | denotes | activin |
| T3 | 56-60 | GeneOrGeneProduct | denotes | GnRH |
| T4 | 87-96 | GeneOrGeneProduct | denotes | secretion |
| T5 | 180-185 | GeneOrGeneProduct | denotes | cells |
| T6 | 187-214 | GeneOrGeneProduct | denotes | bone morphogenetic proteins |
| T7 | 215-222 | GeneOrGeneProduct | denotes | (BMP)-4 |
| T8 | 216-219 | GeneOrGeneProduct | denotes | BMP |
| T9 | 232-239 | GeneOrGeneProduct | denotes | FSHbeta |
| T10 | 240-244 | GeneOrGeneProduct | denotes | mRNA |
| T11 | 276-284 | GeneOrGeneProduct | denotes | contrast |
| T12 | 317-323 | GeneOrGeneProduct | denotes | others |
| T13 | 376-383 | GeneOrGeneProduct | denotes | activin |
| T14 | 395-402 | GeneOrGeneProduct | denotes | FSHbeta |
| T15 | 419-432 | GeneOrGeneProduct | denotes | transcription |
| T16 | 501-506 | GeneOrGeneProduct | denotes | cells |
| T17 | 537-542 | GeneOrGeneProduct | denotes | BMP-4 |
| T18 | 537-540 | GeneOrGeneProduct | denotes | BMP |
| T19 | 560-564 | GeneOrGeneProduct | denotes | mRNA |
| T20 | 569-578 | GeneOrGeneProduct | denotes | secretion |
| T21 | 592-599 | GeneOrGeneProduct | denotes | activin |
| T22 | 604-608 | GeneOrGeneProduct | denotes | GnRH |
| T23 | 610-615 | GeneOrGeneProduct | denotes | BMP-4 |
| T24 | 610-613 | GeneOrGeneProduct | denotes | BMP |
| T25 | 643-653 | GeneOrGeneProduct | denotes | production |
| T26 | 672-679 | GeneOrGeneProduct | denotes | activin |
| T27 | 680-684 | GeneOrGeneProduct | denotes | GnRH |
| T28 | 685-692 | GeneOrGeneProduct | denotes | induced |
| T29 | 708-715 | GeneOrGeneProduct | denotes | FSHbeta |
| T30 | 716-720 | GeneOrGeneProduct | denotes | mRNA |
| T31 | 729-738 | GeneOrGeneProduct | denotes | secretion |
| T32 | 762-773 | GeneOrGeneProduct | denotes | follistatin |
| T33 | 774-778 | GeneOrGeneProduct | denotes | mRNA |
| T34 | 780-785 | GeneOrGeneProduct | denotes | BMP-4 |
| T35 | 780-783 | GeneOrGeneProduct | denotes | BMP |
| T36 | 786-793 | GeneOrGeneProduct | denotes | reduced |
| T37 | 794-800 | GeneOrGeneProduct | denotes | LHbeta |
| T38 | 801-805 | GeneOrGeneProduct | denotes | mRNA |
| T39 | 809-819 | GeneOrGeneProduct | denotes | regulation |
| T40 | 835-839 | GeneOrGeneProduct | denotes | GnRH |
| T41 | 844-851 | GeneOrGeneProduct | denotes | activin |
| T42 | 867-880 | GeneOrGeneProduct | denotes | GnRH receptor |
| T43 | 947-956 | GeneOrGeneProduct | denotes | secretion |
| T44 | 961-969 | GeneOrGeneProduct | denotes | contrast |
| T45 | 1022-1034 | GeneOrGeneProduct | denotes | BMP receptor |
| T46 | 1022-1025 | GeneOrGeneProduct | denotes | BMP |
| T47 | 1045-1051 | GeneOrGeneProduct | denotes | BMPRIA |
| T48 | 1057-1059 | GeneOrGeneProduct | denotes | II |
| T49 | 1061-1067 | GeneOrGeneProduct | denotes | BMPRII |
| T50 | 1078-1083 | GeneOrGeneProduct | denotes | cells |
| T51 | 1097-1103 | GeneOrGeneProduct | denotes | BMPRIB |
| T52 | 1105-1112 | GeneOrGeneProduct | denotes | Smad1/5 |
| T53 | 1129-1136 | GeneOrGeneProduct | denotes | induced |
| T54 | 1140-1145 | GeneOrGeneProduct | denotes | BMP-4 |
| T55 | 1140-1143 | GeneOrGeneProduct | denotes | BMP |
| T56 | 1158-1168 | GeneOrGeneProduct | denotes | activation |
| T57 | 1172-1175 | GeneOrGeneProduct | denotes | BMP |
| T58 | 1209-1214 | GeneOrGeneProduct | denotes | BMP-4 |
| T59 | 1209-1212 | GeneOrGeneProduct | denotes | BMP |
| T60 | 1247-1254 | GeneOrGeneProduct | denotes | activin |
| T61 | 1257-1261 | GeneOrGeneProduct | denotes | GnRH |
| T62 | 1284-1291 | GeneOrGeneProduct | denotes | activin |
| T63 | 1299-1303 | GeneOrGeneProduct | denotes | GnRH |
| T64 | 1333-1338 | GeneOrGeneProduct | denotes | BMP-4 |
| T65 | 1333-1336 | GeneOrGeneProduct | denotes | BMP |
| T66 | 1356-1363 | GeneOrGeneProduct | denotes | activin |
| T67 | 1394-1401 | GeneOrGeneProduct | denotes | Smad2/3 |
| T68 | 1410-1414 | GeneOrGeneProduct | denotes | GnRH |
| T69 | 1415-1422 | GeneOrGeneProduct | denotes | induced |
| T70 | 1423-1429 | GeneOrGeneProduct | denotes | ERK1/2 |
| T71 | 1455-1462 | GeneOrGeneProduct | denotes | binding |
| T72 | 1507-1511 | GeneOrGeneProduct | denotes | GnRH |
| T73 | 1512-1519 | GeneOrGeneProduct | denotes | induced |
| T74 | 1520-1530 | GeneOrGeneProduct | denotes | activation |
| T75 | 1534-1542 | GeneOrGeneProduct | denotes | p38 MAPK |
| T76 | 1560-1565 | GeneOrGeneProduct | denotes | BMP-4 |
| T77 | 1560-1563 | GeneOrGeneProduct | denotes | BMP |
| T78 | 1602-1609 | GeneOrGeneProduct | denotes | FSHbeta |
| T79 | 1610-1614 | GeneOrGeneProduct | denotes | mRNA |
| T80 | 1630-1644 | GeneOrGeneProduct | denotes | secretion, but |
| T81 | 1655-1661 | GeneOrGeneProduct | denotes | LHbeta |
| T82 | 1662-1666 | GeneOrGeneProduct | denotes | mRNA |
| T83 | 1732-1739 | GeneOrGeneProduct | denotes | activin |
| T84 | 1747-1751 | GeneOrGeneProduct | denotes | GnRH |
| T85 | 1799-1804 | GeneOrGeneProduct | denotes | and 2 |
| T86 | 1891-1903 | GeneOrGeneProduct | denotes | BMP receptor |
| T87 | 1891-1894 | GeneOrGeneProduct | denotes | BMP |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-26 | GeneOrGeneProduct | denotes | Bone morphogenetic protein |
| T2 | 44-51 | GeneOrGeneProduct | denotes | activin |
| T3 | 56-60 | GeneOrGeneProduct | denotes | GnRH |
| T4 | 187-214 | GeneOrGeneProduct | denotes | bone morphogenetic proteins |
| T5 | 216-219 | GeneOrGeneProduct | denotes | BMP |
| T6 | 232-239 | GeneOrGeneProduct | denotes | FSHbeta |
| T7 | 240-244 | GeneOrGeneProduct | denotes | mRNA |
| T8 | 376-383 | GeneOrGeneProduct | denotes | activin |
| T9 | 395-402 | GeneOrGeneProduct | denotes | FSHbeta |
| T10 | 419-432 | GeneOrGeneProduct | denotes | transcription |
| T11 | 537-542 | GeneOrGeneProduct | denotes | BMP-4 |
| T12 | 537-540 | GeneOrGeneProduct | denotes | BMP |
| T13 | 560-564 | GeneOrGeneProduct | denotes | mRNA |
| T14 | 592-599 | GeneOrGeneProduct | denotes | activin |
| T15 | 604-608 | GeneOrGeneProduct | denotes | GnRH |
| T16 | 610-615 | GeneOrGeneProduct | denotes | BMP-4 |
| T17 | 610-613 | GeneOrGeneProduct | denotes | BMP |
| T18 | 672-679 | GeneOrGeneProduct | denotes | activin |
| T19 | 680-684 | GeneOrGeneProduct | denotes | GnRH |
| T20 | 708-715 | GeneOrGeneProduct | denotes | FSHbeta |
| T21 | 716-720 | GeneOrGeneProduct | denotes | mRNA |
| T22 | 762-773 | GeneOrGeneProduct | denotes | follistatin |
| T23 | 774-778 | GeneOrGeneProduct | denotes | mRNA |
| T24 | 780-785 | GeneOrGeneProduct | denotes | BMP-4 |
| T25 | 780-783 | GeneOrGeneProduct | denotes | BMP |
| T26 | 786-793 | GeneOrGeneProduct | denotes | reduced |
| T27 | 794-800 | GeneOrGeneProduct | denotes | LHbeta |
| T28 | 801-805 | GeneOrGeneProduct | denotes | mRNA |
| T29 | 835-839 | GeneOrGeneProduct | denotes | GnRH |
| T30 | 844-851 | GeneOrGeneProduct | denotes | activin |
| T31 | 867-880 | GeneOrGeneProduct | denotes | GnRH receptor |
| T32 | 1022-1034 | GeneOrGeneProduct | denotes | BMP receptor |
| T33 | 1022-1025 | GeneOrGeneProduct | denotes | BMP |
| T34 | 1045-1051 | GeneOrGeneProduct | denotes | BMPRIA |
| T35 | 1061-1067 | GeneOrGeneProduct | denotes | BMPRII |
| T36 | 1097-1103 | GeneOrGeneProduct | denotes | BMPRIB |
| T37 | 1105-1112 | GeneOrGeneProduct | denotes | Smad1/5 |
| T38 | 1140-1145 | GeneOrGeneProduct | denotes | BMP-4 |
| T39 | 1140-1143 | GeneOrGeneProduct | denotes | BMP |
| T40 | 1172-1175 | GeneOrGeneProduct | denotes | BMP |
| T41 | 1209-1214 | GeneOrGeneProduct | denotes | BMP-4 |
| T42 | 1209-1212 | GeneOrGeneProduct | denotes | BMP |
| T43 | 1247-1254 | GeneOrGeneProduct | denotes | activin |
| T44 | 1257-1261 | GeneOrGeneProduct | denotes | GnRH |
| T45 | 1284-1291 | GeneOrGeneProduct | denotes | activin |
| T46 | 1299-1303 | GeneOrGeneProduct | denotes | GnRH |
| T47 | 1333-1338 | GeneOrGeneProduct | denotes | BMP-4 |
| T48 | 1333-1336 | GeneOrGeneProduct | denotes | BMP |
| T49 | 1356-1363 | GeneOrGeneProduct | denotes | activin |
| T50 | 1394-1401 | GeneOrGeneProduct | denotes | Smad2/3 |
| T51 | 1410-1414 | GeneOrGeneProduct | denotes | GnRH |
| T52 | 1423-1429 | GeneOrGeneProduct | denotes | ERK1/2 |
| T53 | 1455-1462 | GeneOrGeneProduct | denotes | binding |
| T54 | 1507-1511 | GeneOrGeneProduct | denotes | GnRH |
| T55 | 1534-1542 | GeneOrGeneProduct | denotes | p38 MAPK |
| T56 | 1560-1565 | GeneOrGeneProduct | denotes | BMP-4 |
| T57 | 1560-1563 | GeneOrGeneProduct | denotes | BMP |
| T58 | 1602-1609 | GeneOrGeneProduct | denotes | FSHbeta |
| T59 | 1610-1614 | GeneOrGeneProduct | denotes | mRNA |
| T60 | 1655-1661 | GeneOrGeneProduct | denotes | LHbeta |
| T61 | 1662-1666 | GeneOrGeneProduct | denotes | mRNA |
| T62 | 1732-1739 | GeneOrGeneProduct | denotes | activin |
| T63 | 1747-1751 | GeneOrGeneProduct | denotes | GnRH |
| T64 | 1891-1903 | GeneOrGeneProduct | denotes | BMP receptor |
| T65 | 1891-1894 | GeneOrGeneProduct | denotes | BMP |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-28 | GeneOrGeneProduct | denotes | Bone morphogenetic protein-4 |
| T2 | 44-51 | GeneOrGeneProduct | denotes | activin |
| T3 | 56-60 | GeneOrGeneProduct | denotes | GnRH |
| T4 | 187-214 | GeneOrGeneProduct | denotes | bone morphogenetic proteins |
| T5 | 216-219 | GeneOrGeneProduct | denotes | BMP |
| T6 | 232-239 | GeneOrGeneProduct | denotes | FSHbeta |
| T7 | 376-383 | GeneOrGeneProduct | denotes | activin |
| T8 | 395-402 | GeneOrGeneProduct | denotes | FSHbeta |
| T9 | 537-542 | GeneOrGeneProduct | denotes | BMP-4 |
| T11 | 592-599 | GeneOrGeneProduct | denotes | activin |
| T12 | 604-608 | GeneOrGeneProduct | denotes | GnRH |
| T13 | 610-615 | GeneOrGeneProduct | denotes | BMP-4 |
| T15 | 672-679 | GeneOrGeneProduct | denotes | activin |
| T16 | 680-684 | GeneOrGeneProduct | denotes | GnRH |
| T17 | 708-715 | GeneOrGeneProduct | denotes | FSHbeta |
| T18 | 762-773 | GeneOrGeneProduct | denotes | follistatin |
| T19 | 780-785 | GeneOrGeneProduct | denotes | BMP-4 |
| T21 | 794-800 | GeneOrGeneProduct | denotes | LHbeta |
| T22 | 835-839 | GeneOrGeneProduct | denotes | GnRH |
| T23 | 844-851 | GeneOrGeneProduct | denotes | activin |
| T24 | 867-880 | GeneOrGeneProduct | denotes | GnRH receptor |
| T25 | 1022-1034 | GeneOrGeneProduct | denotes | BMP receptor |
| T27 | 1045-1051 | GeneOrGeneProduct | denotes | BMPRIA |
| T28 | 1061-1067 | GeneOrGeneProduct | denotes | BMPRII |
| T29 | 1097-1103 | GeneOrGeneProduct | denotes | BMPRIB |
| T30 | 1105-1112 | GeneOrGeneProduct | denotes | Smad1/5 |
| T31 | 1140-1145 | GeneOrGeneProduct | denotes | BMP-4 |
| T33 | 1172-1175 | GeneOrGeneProduct | denotes | BMP |
| T34 | 1209-1214 | GeneOrGeneProduct | denotes | BMP-4 |
| T36 | 1247-1254 | GeneOrGeneProduct | denotes | activin |
| T37 | 1257-1261 | GeneOrGeneProduct | denotes | GnRH |
| T38 | 1284-1291 | GeneOrGeneProduct | denotes | activin |
| T39 | 1299-1303 | GeneOrGeneProduct | denotes | GnRH |
| T40 | 1333-1338 | GeneOrGeneProduct | denotes | BMP-4 |
| T42 | 1356-1363 | GeneOrGeneProduct | denotes | activin |
| T43 | 1394-1401 | GeneOrGeneProduct | denotes | Smad2/3 |
| T44 | 1410-1414 | GeneOrGeneProduct | denotes | GnRH |
| T45 | 1423-1429 | GeneOrGeneProduct | denotes | ERK1/2 |
| T46 | 1433-1462 | GeneOrGeneProduct | denotes | cAMP response element-binding |
| T47 | 1507-1511 | GeneOrGeneProduct | denotes | GnRH |
| T48 | 1534-1542 | GeneOrGeneProduct | denotes | p38 MAPK |
| T49 | 1560-1565 | GeneOrGeneProduct | denotes | BMP-4 |
| T51 | 1602-1609 | GeneOrGeneProduct | denotes | FSHbeta |
| T52 | 1655-1661 | GeneOrGeneProduct | denotes | LHbeta |
| T53 | 1732-1739 | GeneOrGeneProduct | denotes | activin |
| T54 | 1747-1751 | GeneOrGeneProduct | denotes | GnRH |
| T55 | 1891-1903 | GeneOrGeneProduct | denotes | BMP receptor |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 170-179 | DiseaseOrPhenotypicFeature | denotes | pituitary | 0021156 |
| T2 | 979-988 | DiseaseOrPhenotypicFeature | denotes | pituitary | 0021156 |
LitCoin_CellLine
| Id | Subject | Object | Predicate | Lexical cue | cellosaurus_accession_id |
|---|---|---|---|---|---|
| T1 | 100-107 | CellLine | denotes | LbetaT2 | CVCL_0398 |
| T2 | 295-302 | CellLine | denotes | LbetaT2 | CVCL_0398 |
| T3 | 493-500 | CellLine | denotes | LbetaT2 | CVCL_0398 |
| T4 | 1070-1077 | CellLine | denotes | LbetaT2 | CVCL_0398 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 260-263 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 |
| T2 | 639-642 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 |
| T3 | 725-728 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 |
| T4 | 912-915 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 |
| T5 | 1433-1437 | ChemicalEntity | denotes | cAMP | http://purl.obolibrary.org/obo/CHEBI_17489 |
| T6 | 1626-1629 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 156-161 | OrganismTaxon | denotes | sheep |
| T2 | 289-294 | OrganismTaxon | denotes | mouse |
| T3 | 973-978 | OrganismTaxon | denotes | sheep |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | ID: | cellosaurus_accession_id |
|---|---|---|---|---|---|---|
| T4 | 1070-1077 | CellLine | denotes | LbetaT2 | CVCL_0398 | |
| T3 | 493-500 | CellLine | denotes | LbetaT2 | CVCL_0398 | |
| T2 | 295-302 | CellLine | denotes | LbetaT2 | CVCL_0398 | |
| T1 | 100-107 | CellLine | denotes | LbetaT2 | CVCL_0398 | |
| T6 | 1626-1629 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 | |
| T5 | 1433-1437 | ChemicalEntity | denotes | cAMP | http://purl.obolibrary.org/obo/CHEBI_17489 | |
| T51936 | 912-915 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 | |
| T735 | 725-728 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 | |
| T4836 | 639-642 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 | |
| T47355 | 260-263 | ChemicalEntity | denotes | FSH | http://purl.obolibrary.org/obo/CHEBI_81569 | |
| T55 | 1891-1903 | GeneOrGeneProduct | denotes | BMP receptor | ||
| T54 | 1747-1751 | GeneOrGeneProduct | denotes | GnRH | ||
| T53 | 1732-1739 | GeneOrGeneProduct | denotes | activin | ||
| T52 | 1655-1661 | GeneOrGeneProduct | denotes | LHbeta | ||
| T51 | 1602-1609 | GeneOrGeneProduct | denotes | FSHbeta | ||
| T49 | 1560-1565 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T48 | 1534-1542 | GeneOrGeneProduct | denotes | p38 MAPK | ||
| T47 | 1507-1511 | GeneOrGeneProduct | denotes | GnRH | ||
| T46 | 1433-1462 | GeneOrGeneProduct | denotes | cAMP response element-binding | ||
| T45 | 1423-1429 | GeneOrGeneProduct | denotes | ERK1/2 | ||
| T44 | 1410-1414 | GeneOrGeneProduct | denotes | GnRH | ||
| T43 | 1394-1401 | GeneOrGeneProduct | denotes | Smad2/3 | ||
| T42 | 1356-1363 | GeneOrGeneProduct | denotes | activin | ||
| T40 | 1333-1338 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T39 | 1299-1303 | GeneOrGeneProduct | denotes | GnRH | ||
| T38 | 1284-1291 | GeneOrGeneProduct | denotes | activin | ||
| T37 | 1257-1261 | GeneOrGeneProduct | denotes | GnRH | ||
| T36 | 1247-1254 | GeneOrGeneProduct | denotes | activin | ||
| T34 | 1209-1214 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T33 | 1172-1175 | GeneOrGeneProduct | denotes | BMP | ||
| T31 | 1140-1145 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T30 | 1105-1112 | GeneOrGeneProduct | denotes | Smad1/5 | ||
| T29 | 1097-1103 | GeneOrGeneProduct | denotes | BMPRIB | ||
| T28 | 1061-1067 | GeneOrGeneProduct | denotes | BMPRII | ||
| T27 | 1045-1051 | GeneOrGeneProduct | denotes | BMPRIA | ||
| T25 | 1022-1034 | GeneOrGeneProduct | denotes | BMP receptor | ||
| T24 | 867-880 | GeneOrGeneProduct | denotes | GnRH receptor | ||
| T23 | 844-851 | GeneOrGeneProduct | denotes | activin | ||
| T22 | 835-839 | GeneOrGeneProduct | denotes | GnRH | ||
| T21 | 794-800 | GeneOrGeneProduct | denotes | LHbeta | ||
| T19 | 780-785 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T18 | 762-773 | GeneOrGeneProduct | denotes | follistatin | ||
| T17 | 708-715 | GeneOrGeneProduct | denotes | FSHbeta | ||
| T16 | 680-684 | GeneOrGeneProduct | denotes | GnRH | ||
| T15 | 672-679 | GeneOrGeneProduct | denotes | activin | ||
| T13 | 610-615 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T12 | 604-608 | GeneOrGeneProduct | denotes | GnRH | ||
| T11 | 592-599 | GeneOrGeneProduct | denotes | activin | ||
| T9 | 537-542 | GeneOrGeneProduct | denotes | BMP-4 | ||
| T8 | 395-402 | GeneOrGeneProduct | denotes | FSHbeta | ||
| T7 | 376-383 | GeneOrGeneProduct | denotes | activin | ||
| T26386 | 232-239 | GeneOrGeneProduct | denotes | FSHbeta | ||
| T85914 | 216-219 | GeneOrGeneProduct | denotes | BMP | ||
| T85700 | 187-214 | GeneOrGeneProduct | denotes | bone morphogenetic proteins | ||
| T21513 | 56-60 | GeneOrGeneProduct | denotes | GnRH | ||
| T90527 | 44-51 | GeneOrGeneProduct | denotes | activin | ||
| T1171 | 0-28 | GeneOrGeneProduct | denotes | Bone morphogenetic protein-4 | ||
| T19868 | 973-978 | OrganismTaxon | denotes | sheep | ||
| T93462 | 289-294 | OrganismTaxon | denotes | mouse | ||
| T50387 | 156-161 | OrganismTaxon | denotes | sheep |