
PubMed:18310305
Annnotations
Glycan-Motif
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 95-109 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
T2 | 261-275 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
T3 | 277-283 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T4 | 513-519 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T5 | 915-921 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T6 | 1205-1211 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 67-73 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
T2 | 95-109 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
T3 | 102-109 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
T5 | 227-233 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
T6 | 261-275 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
T7 | 268-275 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
T9 | 277-283 | Glycan_Motif | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
T10 | 513-519 | Glycan_Motif | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
T11 | 884-890 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
T12 | 915-921 | Glycan_Motif | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
T13 | 1167-1173 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
T14 | 1205-1211 | Glycan_Motif | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 95-109 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
T2 | 102-109 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
T3 | 261-275 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
T4 | 268-275 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
PMID_GLOBAL
Id | Subject | Object | Predicate | Lexical cue | cellosaurus_accession_id |
---|---|---|---|---|---|
T1 | 44-50 | CellLine | denotes | WEHI-3 | CVCL_3622 |
T2 | 700-706 | CellLine | denotes | WEHI-3 | CVCL_3622 |
T3 | 845-851 | CellLine | denotes | WEHI-3 | CVCL_3622 |
T4 | 1044-1050 | CellLine | denotes | WEHI-3 | CVCL_3622 |
T5 | 1089-1095 | CellLine | denotes | WEHI-3 | CVCL_3622 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
TextSentencer_T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
TextSentencer_T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
TextSentencer_T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
TextSentencer_T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
TextSentencer_T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
TextSentencer_T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 95-109 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
T2 | 102-109 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
T3 | 102-109 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
T4 | 261-275 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
T5 | 268-275 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
T6 | 268-275 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
T7 | 277-283 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T8 | 513-519 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T9 | 915-921 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
T10 | 1205-1211 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | SLe(x) |
uniprot-human
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-6 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T2 | 209-215 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T3 | 385-391 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T4 | 593-599 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T5 | 655-661 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T6 | 833-839 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T7 | 970-976 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T8 | 1125-1131 | http://www.uniprot.org/uniprot/Q14242 | denotes | PSGL-1 |
T9 | 179-189 | http://www.uniprot.org/uniprot/P16109 | denotes | P-selectin |
T10 | 416-426 | http://www.uniprot.org/uniprot/P16109 | denotes | P-selectin |
T11 | 181-195 | http://www.uniprot.org/uniprot/P14151 | denotes | selectin and L |
uniprot-mouse
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-6 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T2 | 209-215 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T3 | 385-391 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T4 | 593-599 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T5 | 655-661 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T6 | 833-839 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T7 | 970-976 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T8 | 1125-1131 | http://www.uniprot.org/uniprot/Q62170 | denotes | PSGL-1 |
T9 | 179-189 | http://www.uniprot.org/uniprot/Q01102 | denotes | P-selectin |
T10 | 416-426 | http://www.uniprot.org/uniprot/Q01102 | denotes | P-selectin |
T11 | 181-195 | http://www.uniprot.org/uniprot/P18337 | denotes | selectin and L |
GlycoBiology-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 485-490 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T2 | 852-857 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T3 | 1051-1056 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T4 | 1096-1101 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
T5 | 1135-1156 | http://purl.bioontology.org/ontology/STY/T045 | denotes | generate functionally |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 95-101 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
T2 | 261-267 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
T3 | 873-883 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
T4 | 119-140 | http://purl.obolibrary.org/obo/GO_0050900 | denotes | Leukocyte trafficking |
T5 | 444-456 | http://purl.obolibrary.org/obo/GO_0050501 | denotes | activity has |
T6 | 600-613 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T7 | 662-675 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T8 | 713-722 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolic |
T9 | 936-947 | http://purl.obolibrary.org/obo/GO_0036065 | denotes | fucosylated |
T10 | 1114-1124 | http://purl.obolibrary.org/obo/GO_0036065 | denotes | fucosylate |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 181-189 | http://purl.obolibrary.org/obo/GO_0030246 | denotes | selectin |
T2 | 196-204 | http://purl.obolibrary.org/obo/GO_0030246 | denotes | selectin |
T3 | 418-426 | http://purl.obolibrary.org/obo/GO_0030246 | denotes | selectin |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 34-38 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T2 | 485-490 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T3 | 852-857 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T4 | 1051-1056 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5 | 1096-1101 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T6 | 67-71 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
T7 | 227-231 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
T8 | 884-888 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
T9 | 1167-1171 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
GlycoBiology-Motifs
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 95-107 | http://rdf.glycoinfo.org/glycan/G00053MO | denotes | sialyl Lewis |
T2 | 261-273 | http://rdf.glycoinfo.org/glycan/G00053MO | denotes | sialyl Lewis |
T3 | 95-109 | http://rdf.glycoinfo.org/glycan/G00054MO | denotes | sialyl Lewis x |
T4 | 261-275 | http://rdf.glycoinfo.org/glycan/G00054MO | denotes | sialyl Lewis x |
T5 | 102-107 | http://rdf.glycoinfo.org/glycan/G00047MO | denotes | Lewis |
T6 | 268-273 | http://rdf.glycoinfo.org/glycan/G00047MO | denotes | Lewis |
T7 | 102-109 | http://rdf.glycoinfo.org/glycan/G00051MO | denotes | Lewis x |
T8 | 268-275 | http://rdf.glycoinfo.org/glycan/G00051MO | denotes | Lewis x |
Lectin
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
Lectin_T1 | 181-189 | https://acgg.asia/db/lfdb/LfDB0043 | denotes | selectin |
Lectin_T2 | 196-204 | https://acgg.asia/db/lfdb/LfDB0043 | denotes | selectin |
Lectin_T3 | 418-426 | https://acgg.asia/db/lfdb/LfDB0043 | denotes | selectin |
Lectin_T4 | 179-189 | https://acgg.asia/db/lfdb/LfDB0013 | denotes | P-selectin |
Lectin_T5 | 196-204 | https://acgg.asia/db/lfdb/LfDB0013 | denotes | selectin |
Lectin_T6 | 416-426 | https://acgg.asia/db/lfdb/LfDB0013 | denotes | P-selectin |
Lectin_T7 | 181-189 | https://acgg.asia/db/lfdb/LfDB0142 | denotes | selectin |
Lectin_T8 | 194-204 | https://acgg.asia/db/lfdb/LfDB0142 | denotes | L-selectin |
Lectin_T9 | 418-426 | https://acgg.asia/db/lfdb/LfDB0142 | denotes | selectin |
GlycoBiology-Epitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoEpitope-B_T1 | 95-107 | http://www.glycoepitope.jp/epitopes/EP0008 | denotes | sialyl Lewis |
PD-GlycoEpitope-B_T2 | 261-273 | http://www.glycoepitope.jp/epitopes/EP0008 | denotes | sialyl Lewis |
PD-GlycoEpitope-B_T3 | 95-109 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
PD-GlycoEpitope-B_T4 | 261-275 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
PD-GlycoEpitope-B_T5 | 102-109 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
PD-GlycoEpitope-B_T6 | 268-275 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
HP-phenotype
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 277-280 | Phenotype | denotes | SLe | HP:0002725 |
T2 | 513-516 | Phenotype | denotes | SLe | HP:0002725 |
T3 | 915-918 | Phenotype | denotes | SLe | HP:0002725 |
T4 | 1205-1208 | Phenotype | denotes | SLe | HP:0002725 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 67-73 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T2 | 95-109 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T3 | 227-233 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T4 | 261-275 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T5 | 884-890 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T6 | 1167-1173 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
GlyCosmos15-CL
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 23-33 | Cell | denotes | leukocytic | http://purl.obolibrary.org/obo/CL:0000738 |
T2 | 119-128 | Cell | denotes | Leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
T3 | 374-384 | Cell | denotes | neutrophil | http://purl.obolibrary.org/obo/CL:0000775 |
T4 | 1015-1024 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
TextSentencer_T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
TextSentencer_T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
TextSentencer_T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
TextSentencer_T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
TextSentencer_T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
TextSentencer_T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-118 | Sentence | denotes | PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen. |
T2 | 119-293 | Sentence | denotes | Leukocyte trafficking involves specific recognition between P-selectin and L-selectin and PSGL-1 containing core 2-based O-glycans expressing sialyl Lewis x (SLe(x)) antigen. |
T3 | 294-614 | Sentence | denotes | However, the structural identity of the glycan component(s) displayed by murine neutrophil PSGL-1 that contributes to its P-selectin counter-receptor activity has been uncertain, since these cells express little if any SLe(x) antigen, and because there have been no direct studies to examine murine PSGL-1 glycosylation. |
T4 | 615-817 | Sentence | denotes | To address this uncertainty, we studied PSGL-1 glycosylation in the murine cell line WEHI-3 using metabolic-radiolabeling with (3)H-monosaccharide precursors to detect low-abundance O-glycan structures. |
T5 | 818-930 | Sentence | denotes | We report that PSGL-1 from WEHI-3 cells expresses a di-sialylated core 2 O-glycan containing the SLe(x) antigen. |
T6 | 931-1057 | Sentence | denotes | This fucosylated O-glycan is scarce on PSGL-1 and essentially undetectable in total leukocyte glycoproteins from WEHI-3 cells. |
T7 | 1058-1220 | Sentence | denotes | These results demonstrate that WEHI-3 cells selectively fucosylate PSGL-1 to generate functionally important core 2-based O-glycans containing the SLe(x) antigen. |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 95-109 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
T2 | 261-275 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
GlyCosmos15-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 119-128 | Body_part | denotes | Leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
T2 | 374-384 | Body_part | denotes | neutrophil | http://purl.obolibrary.org/obo/CL_0000775 |
T3 | 1015-1024 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
GlyCosmos15-FMA
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 23-33 | Body_part | denotes | leukocytic | FMA:62852 |
T2 | 119-128 | Body_part | denotes | Leukocyte | FMA:62852 |
T3 | 374-384 | Body_part | denotes | neutrophil | FMA:62860 |
T4 | 1015-1024 | Body_part | denotes | leukocyte | FMA:62852 |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 67-73 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T2 | 95-109 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T3 | 227-233 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T4 | 261-275 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T5 | 277-283 | Glycan | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T6 | 513-519 | Glycan | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T7 | 884-890 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T8 | 915-921 | Glycan | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
T9 | 1167-1173 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
T10 | 1205-1211 | Glycan | denotes | SLe(x) | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 95-109 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
T2 | 261-275 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 119-128 | Body_part | denotes | Leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
T2 | 374-384 | Body_part | denotes | neutrophil | http://purl.obolibrary.org/obo/CL_0000775 |
T3 | 1015-1024 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
CL-cell
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 23-33 | Cell | denotes | leukocytic | http://purl.obolibrary.org/obo/CL:0000738 |
T2 | 119-128 | Cell | denotes | Leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
T3 | 374-384 | Cell | denotes | neutrophil | http://purl.obolibrary.org/obo/CL:0000775 |
T4 | 1015-1024 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |