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PubMed:1827138 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 11-23 protein denotes murine TCF-1
T2 43-63 protein denotes transcription factor
T3 81-98 DNA denotes functional motifs
T4 106-153 DNA denotes CD3-epsilon and T cell receptor alpha enhancers
T5 155-158 protein denotes CD3
T6 202-216 cell_line denotes T cell lineage
T7 259-285 protein denotes human transcription factor
T8 287-292 protein denotes TCF-1
T9 415-420 protein denotes TCF-1
T10 450-465 cell_type denotes T lineage cells
T11 467-472 protein denotes TCF-1
T12 541-567 DNA denotes mobility group 1 (HMG) box
T13 599-611 protein denotes murine TCF-1
T14 690-701 protein denotes human TCF-1
T15 703-725 protein denotes Murine and human TCF-1
T16 773-807 protein denotes Recombinant murine and human TCF-1
T17 850-870 DNA denotes CD3-epsilon enhancer
T18 946-964 DNA denotes murine cDNA clones
T19 984-989 protein denotes TCF-1
T20 1056-1061 protein denotes TCF-1
T21 1077-1084 DNA denotes HMG box
T22 1203-1208 protein denotes TCF-1
T23 1305-1310 protein denotes TCF-1
T24 1346-1369 DNA denotes T cell-specific element
T25 1377-1419 DNA denotes T cell receptor alpha (TCR-alpha) enhancer
T26 1501-1536 DNA denotes TCR-alpha and CD3-epsilon enhancers
T27 1565-1570 protein denotes TCF-1
T28 1599-1622 cell_type denotes mature T cell phenotype

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-154 Sentence denotes Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.
S2 155-217 Sentence denotes CD3-epsilon gene expression is confined to the T cell lineage.
S3 218-382 Sentence denotes We have recently identified and cloned a human transcription factor, TCF-1, that binds to a functional element in the T lymphocyte-specific enhancer of CD3-epsilon.
S4 383-466 Sentence denotes In a panel of human cell lines, TCF-1 expression was restricted to T lineage cells.
S5 467-568 Sentence denotes TCF-1 belonged to a novel family of genes that contain the so-called high mobility group 1 (HMG) box.
S6 569-612 Sentence denotes Here we report the cloning of murine TCF-1.
S7 613-702 Sentence denotes Two splice alternatives were identified that were not previously observed in human TCF-1.
S8 703-772 Sentence denotes Murine and human TCF-1 displayed a 95.5% overall amino acid homology.
S9 773-936 Sentence denotes Recombinant murine and human TCF-1 recognized the same sequence motif in the CD3-epsilon enhancer as judged by gel retardation and methylation interference assays.
S10 937-1004 Sentence denotes With the murine cDNA clones several aspects of TCF-1 were analyzed.
S11 1005-1130 Sentence denotes First, deletion analysis revealed that a region of TCF-1 containing the HMG box was sufficient for sequence-specific binding.
S12 1131-1297 Sentence denotes Second, by high stringency Northern blotting and in situ hybridization, TCF-1 expression was shown to be confined to the thymus and to the T cell areas of the spleen.
S13 1298-1420 Sentence denotes Third, TCF-1 bound specifically to a functional T cell-specific element in the T cell receptor alpha (TCR-alpha) enhancer.
S14 1421-1623 Sentence denotes The T lineage-specific expression and the affinity for functional motifs in the TCR-alpha and CD3-epsilon enhancers imply an important role for TCF-1 in the establishment of the mature T cell phenotype.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 18-23 NP denotes TCF-1
C1 11-23 NP denotes murine TCF-1
C4 102-117 NP denotes the CD3-epsilon
C5 122-153 NP denotes T cell receptor alpha enhancers
C3 25-153 NP denotes a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers
C6 155-166 NP denotes CD3-epsilon
C7 198-216 NP denotes the T cell lineage
C8 257-285 NP denotes a human transcription factor
C9 287-292 NP denotes TCF-1
C10 294-298 NP denotes that
C11 370-381 NP denotes CD3-epsilon
C13 415-420 NP denotes TCF-1
C12 415-431 NP denotes TCF-1 expression
C14 450-465 NP denotes T lineage cells
C15 467-472 NP denotes TCF-1
C16 485-508 NP denotes a novel family of genes
C17 509-513 NP denotes that
C18 536-567 NP denotes high mobility group 1 (HMG) box
C20 606-611 NP denotes TCF-1
C19 599-611 NP denotes murine TCF-1
C22 696-701 NP denotes TCF-1
C21 690-701 NP denotes human TCF-1
C24 720-725 NP denotes TCF-1
C23 714-725 NP denotes human TCF-1
C26 802-807 NP denotes TCF-1
C25 796-807 NP denotes human TCF-1
C27 846-870 NP denotes the CD3-epsilon enhancer
C28 984-989 NP denotes TCF-1
C29 1012-1029 NP denotes deletion analysis
C30 1039-1043 NP denotes that
C31 1056-1061 NP denotes TCF-1
C32 1073-1084 NP denotes the HMG box
C34 1203-1208 NP denotes TCF-1
C33 1203-1219 NP denotes TCF-1 expression
C35 1305-1310 NP denotes TCF-1
C37 1399-1410 NP denotes (TCR-alpha)
C36 1373-1419 NP denotes the T cell receptor alpha (TCR-alpha) enhancer
C38 1497-1510 NP denotes the TCR-alpha
C39 1515-1536 NP denotes CD3-epsilon enhancers
C40 1565-1570 NP denotes TCF-1
R1 C3 C1 coref-appos a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers,murine TCF-1
R2 C6 C4 coref-ident CD3-epsilon,the CD3-epsilon
R3 C8 C9 coref-appos a human transcription factor,TCF-1
R4 C9 C2 coref-ident TCF-1,TCF-1
R5 C10 C9 coref-relat that,TCF-1
R6 C11 C6 coref-ident CD3-epsilon,CD3-epsilon
R7 C13 C9 coref-ident TCF-1,TCF-1
R8 C14 C7 coref-ident T lineage cells,the T cell lineage
R9 C15 C13 coref-ident TCF-1,TCF-1
R10 C17 C16 coref-relat that,a novel family of genes
R11 C20 C15 coref-ident TCF-1,TCF-1
R12 C19 C1 coref-ident murine TCF-1,murine TCF-1
R13 C22 C20 coref-ident TCF-1,TCF-1
R14 C21 C8 coref-ident human TCF-1,a human transcription factor
R15 C24 C22 coref-ident TCF-1,TCF-1
R16 C23 C21 coref-ident human TCF-1,human TCF-1
R17 C26 C24 coref-ident TCF-1,TCF-1
R18 C25 C23 coref-ident human TCF-1,human TCF-1
R19 C27 C11 coref-other the CD3-epsilon enhancer,CD3-epsilon
R20 C28 C26 coref-ident TCF-1,TCF-1
R21 C30 C29 coref-relat that,deletion analysis
R22 C31 C28 coref-ident TCF-1,TCF-1
R23 C32 C18 coref-ident the HMG box,high mobility group 1 (HMG) box
R24 C34 C31 coref-ident TCF-1,TCF-1
R25 C33 C12 coref-ident TCF-1 expression,TCF-1 expression
R26 C35 C34 coref-ident TCF-1,TCF-1
R27 C37 C36 coref-other (TCR-alpha),the T cell receptor alpha (TCR-alpha) enhancer
R28 C36 C5 coref-ident the T cell receptor alpha (TCR-alpha) enhancer,T cell receptor alpha enhancers
R29 C38 C37 coref-ident the TCR-alpha,(TCR-alpha)
R30 C39 C27 coref-ident CD3-epsilon enhancers,the CD3-epsilon enhancer
R31 C40 C35 coref-ident TCF-1,TCF-1

GENIAcorpus

Id Subject Object Predicate Lexical cue
T15 752-771 other_name denotes amino acid homology
T16 850-870 DNA_domain_or_region denotes CD3-epsilon enhancer
T17 884-899 other_name denotes gel retardation
T18 904-935 other_name denotes methylation interference assays
T19 946-964 DNA_molecule denotes murine cDNA clones
T20 984-989 protein_molecule denotes TCF-1
T21 1012-1029 other_name denotes deletion analysis
T22 1056-1061 protein_molecule denotes TCF-1
T23 1077-1084 DNA_domain_or_region denotes HMG box
T24 1104-1129 other_name denotes sequence-specific binding
T25 1142-1175 other_name denotes high stringency Northern blotting
T26 1180-1201 other_name denotes in situ hybridization
T27 1203-1208 protein_molecule denotes TCF-1
T28 1252-1258 body_part denotes thymus
T29 1290-1296 body_part denotes spleen
T30 1305-1310 protein_molecule denotes TCF-1
T31 1346-1369 DNA_domain_or_region denotes T cell-specific element
T32 1377-1419 DNA_domain_or_region denotes T cell receptor alpha (TCR-alpha) enhancer
T33 1425-1454 other_name denotes T lineage-specific expression
T34 1476-1493 DNA_substructure denotes functional motifs
T35 1565-1570 protein_molecule denotes TCF-1
T36 1599-1622 cell_type denotes mature T cell phenotype
T1 11-23 protein_molecule denotes murine TCF-1
T2 43-63 protein_family_or_group denotes transcription factor
T3 81-98 DNA_domain_or_region denotes functional motifs
T4 155-158 protein_molecule denotes CD3
T5 202-216 cell_line denotes T cell lineage
T6 259-285 protein_family_or_group denotes human transcription factor
T7 287-292 protein_molecule denotes TCF-1
T8 415-420 protein_molecule denotes TCF-1
T9 450-465 cell_type denotes T lineage cells
T10 467-472 protein_molecule denotes TCF-1
T11 541-567 DNA_domain_or_region denotes mobility group 1 (HMG) box
T12 599-605 protein_molecule denotes murine
T13 606-611 protein_molecule denotes TCF-1
T14 690-701 protein_molecule denotes human TCF-1