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PubMed:18180301 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-58 Sentence denotes TIC62 redox-regulated translocon composition and dynamics.
T2 59-210 Sentence denotes The preprotein translocon at the inner envelope of chloroplasts (Tic complex) facilitates the import of nuclear-encoded preproteins into the organelle.
T3 211-263 Sentence denotes Seven distinct subunits have been identified so far.
T4 264-377 Sentence denotes For each of those, specific functions have been proposed based on structural prediction or experimental evidence.
T5 378-493 Sentence denotes Three of those subunits possess modules that could act as redox-active regulatory components in the import process.
T6 494-581 Sentence denotes To date, however, the mode of redox regulation of the import process remains enigmatic.
T7 582-757 Sentence denotes To investigate how the chloroplast redox state influences translocon behavior and composition, we studied the Tic component and the putative redox sensor Tic62 in more detail.
T8 758-963 Sentence denotes The experimental results provide evidence that Tic62 can act as a bona fide dehydrogenase in vitro, and that it changes its localization in the chloroplast dependent on the NADP+/NADPH ratio in the stroma.
T9 964-1099 Sentence denotes Moreover, the redox state influences the interactions of Tic62 with the translocon and the flavoenzyme ferredoxin-NADP+ oxidoreductase.
T10 1100-1295 Sentence denotes Additionally, we give initial experimental insights into the Tic62 structure using circular dichroism measurements and demonstrate that the protein consists of two structurally different domains.
T11 1296-1446 Sentence denotes Our results indicate that Tic62 possesses redox-dependent properties that would allow it to fulfill a role as redox sensor protein in the chloroplast.
T1 0-58 Sentence denotes TIC62 redox-regulated translocon composition and dynamics.
T2 59-210 Sentence denotes The preprotein translocon at the inner envelope of chloroplasts (Tic complex) facilitates the import of nuclear-encoded preproteins into the organelle.
T3 211-263 Sentence denotes Seven distinct subunits have been identified so far.
T4 264-377 Sentence denotes For each of those, specific functions have been proposed based on structural prediction or experimental evidence.
T5 378-493 Sentence denotes Three of those subunits possess modules that could act as redox-active regulatory components in the import process.
T6 494-581 Sentence denotes To date, however, the mode of redox regulation of the import process remains enigmatic.
T7 582-757 Sentence denotes To investigate how the chloroplast redox state influences translocon behavior and composition, we studied the Tic component and the putative redox sensor Tic62 in more detail.
T8 758-963 Sentence denotes The experimental results provide evidence that Tic62 can act as a bona fide dehydrogenase in vitro, and that it changes its localization in the chloroplast dependent on the NADP+/NADPH ratio in the stroma.
T9 964-1099 Sentence denotes Moreover, the redox state influences the interactions of Tic62 with the translocon and the flavoenzyme ferredoxin-NADP+ oxidoreductase.
T10 1100-1295 Sentence denotes Additionally, we give initial experimental insights into the Tic62 structure using circular dichroism measurements and demonstrate that the protein consists of two structurally different domains.
T11 1296-1446 Sentence denotes Our results indicate that Tic62 possesses redox-dependent properties that would allow it to fulfill a role as redox sensor protein in the chloroplast.

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 98-106 Body_part denotes envelope http://purl.obolibrary.org/obo/GO_0031975
T2 200-209 Body_part denotes organelle http://purl.obolibrary.org/obo/GO_0043226
T3 956-962 Body_part denotes stroma http://purl.obolibrary.org/obo/UBERON_0003891