> top > docs > PubMed:1811854 > annotations

PubMed:1811854 JSONTXT

Annnotations TAB JSON ListView MergeView

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 53-57 Glycan_Motif denotes GM1b https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G03277YI
T2 118-122 Glycan_Motif denotes GM1b https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G03277YI

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 53-57 https://glytoucan.org/Structures/Glycans/G03277YI denotes GM1b
T2 118-122 https://glytoucan.org/Structures/Glycans/G03277YI denotes GM1b

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 53-57 http://www.glycoepitope.jp/epitopes/EP0048 denotes GM1b
T2 118-122 http://www.glycoepitope.jp/epitopes/EP0048 denotes GM1b

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-86 Sentence denotes Regio- and stereo-selective synthesis of ganglioside GM1b and some positional analogs.
TextSentencer_T2 87-193 Sentence denotes Total syntheses of ganglioside GM1b (IV3NeuAcGgOse4Cer) and three of its positional analogs are described.
TextSentencer_T3 194-643 Sentence denotes Methyl O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D- glycero-alpha-D-galacto-2-nonulopyranosylonate)- (2----3)-2,4,6-tri-O-benzoyl-1-thio-beta-D-galactopyranoside (7) and methyl O-(methyl 5- acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-2 -nonulopyranosylonate)-(2----6)-2,4-di-O-benzoyl-3-O-benzyl-1-thio - beta-D-galactopyranoside (8) were the key glycosyl donors, prepared according to our reported methods.
TextSentencer_T4 644-1058 Sentence denotes Coupling of 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-alpha-D-galactopyranosyl bromide and 2-(trimethylsilyl)ethyl O-(2,3,6-tri-O-benzyl-beta-D- galactopyranosyl)-(1----4)-2,3,6-tri-O-benzyl-beta-D-glucopyranoside gave a trisaccharide, which after removal of O-acetyl and phthaloyl groups was converted separately, by benzylidenation and dibutyltin oxide-mediated selective benzylation, into two glycosyl acceptors.
TextSentencer_T5 1059-1217 Sentence denotes These were suitable respectively for C-3 and C-6 glycosylation reactions, promoted by dimethyl(methylthio)sulfonium triflate (DMTST), with the donors 7 and 8.
TextSentencer_T6 1218-1404 Sentence denotes The four possible coupling reactions gave the corresponding four pentasaccharide derivatives in high yields, and these were transformed into their respective alpha-trichloroacetimidates.
TextSentencer_T7 1405-1772 Sentence denotes Glycosylation of (2S,3R,4E)-2-azido-3-O-benzoyl-4-octadecene-1,3-diol with the alpha-trichloroacetimidates gave the corresponding beta-glycosides, which on channeling through selective reduction of the azido group, coupling of the thus formed amino group with octadecanoic acid, O-deacetylation, and saponification of the methyl ester group, gave the title compounds.
T1 0-86 Sentence denotes Regio- and stereo-selective synthesis of ganglioside GM1b and some positional analogs.
T2 87-193 Sentence denotes Total syntheses of ganglioside GM1b (IV3NeuAcGgOse4Cer) and three of its positional analogs are described.
T3 194-643 Sentence denotes Methyl O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D- glycero-alpha-D-galacto-2-nonulopyranosylonate)- (2----3)-2,4,6-tri-O-benzoyl-1-thio-beta-D-galactopyranoside (7) and methyl O-(methyl 5- acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-2 -nonulopyranosylonate)-(2----6)-2,4-di-O-benzoyl-3-O-benzyl-1-thio - beta-D-galactopyranoside (8) were the key glycosyl donors, prepared according to our reported methods.
T4 644-1058 Sentence denotes Coupling of 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-alpha-D-galactopyranosyl bromide and 2-(trimethylsilyl)ethyl O-(2,3,6-tri-O-benzyl-beta-D- galactopyranosyl)-(1----4)-2,3,6-tri-O-benzyl-beta-D-glucopyranoside gave a trisaccharide, which after removal of O-acetyl and phthaloyl groups was converted separately, by benzylidenation and dibutyltin oxide-mediated selective benzylation, into two glycosyl acceptors.
T5 1059-1217 Sentence denotes These were suitable respectively for C-3 and C-6 glycosylation reactions, promoted by dimethyl(methylthio)sulfonium triflate (DMTST), with the donors 7 and 8.
T6 1218-1404 Sentence denotes The four possible coupling reactions gave the corresponding four pentasaccharide derivatives in high yields, and these were transformed into their respective alpha-trichloroacetimidates.
T7 1405-1772 Sentence denotes Glycosylation of (2S,3R,4E)-2-azido-3-O-benzoyl-4-octadecene-1,3-diol with the alpha-trichloroacetimidates gave the corresponding beta-glycosides, which on channeling through selective reduction of the azido group, coupling of the thus formed amino group with octadecanoic acid, O-deacetylation, and saponification of the methyl ester group, gave the title compounds.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 53-57 Glycan denotes GM1b https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI
T2 118-122 Glycan denotes GM1b https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 53-57 Glycan denotes GM1b https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI
T2 118-122 Glycan denotes GM1b https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 231-238 Organism denotes tetra-O 100829
T2 417-424 Organism denotes tetra-O 100829

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 53-57 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1b http://www.glycoepitope.jp/epitopes/EP0048
T2 118-122 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1b http://www.glycoepitope.jp/epitopes/EP0048

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-86 Sentence denotes Regio- and stereo-selective synthesis of ganglioside GM1b and some positional analogs.
T2 87-193 Sentence denotes Total syntheses of ganglioside GM1b (IV3NeuAcGgOse4Cer) and three of its positional analogs are described.
T3 194-643 Sentence denotes Methyl O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D- glycero-alpha-D-galacto-2-nonulopyranosylonate)- (2----3)-2,4,6-tri-O-benzoyl-1-thio-beta-D-galactopyranoside (7) and methyl O-(methyl 5- acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-2 -nonulopyranosylonate)-(2----6)-2,4-di-O-benzoyl-3-O-benzyl-1-thio - beta-D-galactopyranoside (8) were the key glycosyl donors, prepared according to our reported methods.
T4 644-1058 Sentence denotes Coupling of 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-alpha-D-galactopyranosyl bromide and 2-(trimethylsilyl)ethyl O-(2,3,6-tri-O-benzyl-beta-D- galactopyranosyl)-(1----4)-2,3,6-tri-O-benzyl-beta-D-glucopyranoside gave a trisaccharide, which after removal of O-acetyl and phthaloyl groups was converted separately, by benzylidenation and dibutyltin oxide-mediated selective benzylation, into two glycosyl acceptors.
T5 1059-1217 Sentence denotes These were suitable respectively for C-3 and C-6 glycosylation reactions, promoted by dimethyl(methylthio)sulfonium triflate (DMTST), with the donors 7 and 8.
T6 1218-1404 Sentence denotes The four possible coupling reactions gave the corresponding four pentasaccharide derivatives in high yields, and these were transformed into their respective alpha-trichloroacetimidates.
T7 1405-1772 Sentence denotes Glycosylation of (2S,3R,4E)-2-azido-3-O-benzoyl-4-octadecene-1,3-diol with the alpha-trichloroacetimidates gave the corresponding beta-glycosides, which on channeling through selective reduction of the azido group, coupling of the thus formed amino group with octadecanoic acid, O-deacetylation, and saponification of the methyl ester group, gave the title compounds.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 231-238 OrganismTaxon denotes tetra-O 100829
T2 417-424 OrganismTaxon denotes tetra-O 100829

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 53-57 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1b http://www.glycoepitope.jp/epitopes/EP0048
T2 118-122 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1b http://www.glycoepitope.jp/epitopes/EP0048