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PubMed:17903229 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-135 Sentence denotes Annual surveillance by CA125 and transvaginal ultrasound for ovarian cancer in both high-risk and population risk women is ineffective.
TextSentencer_T2 136-146 Sentence denotes OBJECTIVE:
TextSentencer_T3 147-260 Sentence denotes To assess the efficacy of annual CA125 and transvaginal ultrasound (TVU) scan as surveillance for ovarian cancer.
TextSentencer_T4 261-268 Sentence denotes DESIGN:
TextSentencer_T5 269-289 Sentence denotes Retrospective audit.
TextSentencer_T6 290-309 Sentence denotes SETTING: NHS Trust.
TextSentencer_T7 310-321 Sentence denotes POPULATION:
TextSentencer_T8 322-407 Sentence denotes Three hundred and forty-one asymptomatic women enrolled for ovarian cancer screening:
TextSentencer_T9 408-627 Sentence denotes 179 were in a high-risk group (>10% lifetime risk of developing ovarian cancer), 77 in a moderate risk group (4-10% lifetime risk of developing ovarian cancer) and 71 in a near population risk group (<4% lifetime risk).
TextSentencer_T10 628-636 Sentence denotes METHODS:
TextSentencer_T11 637-768 Sentence denotes Retrospective audit of case records, laboratory CA125 results, radiology reports, histology records and local cancer registry data.
TextSentencer_T12 769-791 Sentence denotes MAIN OUTCOME MEASURES:
TextSentencer_T13 792-838 Sentence denotes Ovarian cancers occurring in study population.
TextSentencer_T14 839-990 Sentence denotes Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of TVU, and CA125 as a screening tool for ovarian cancer.
TextSentencer_T15 991-999 Sentence denotes RESULTS:
TextSentencer_T16 1000-1057 Sentence denotes Four ovarian cancers and one endometrial cancer occurred.
TextSentencer_T17 1058-1180 Sentence denotes One ovarian cancer was detected at surveillance, three occurred in women who presented symptomatically between screenings.
TextSentencer_T18 1181-1269 Sentence denotes Thirty women underwent exploratory surgery because of abnormal findings at surveillance.
TextSentencer_T19 1270-1361 Sentence denotes Two women had cancer (PPV = 6.7%); one had ovarian cancer and the other endometrial cancer.
TextSentencer_T20 1362-1407 Sentence denotes Twenty-eight women (93.3%) had no malignancy.
TextSentencer_T21 1408-1519 Sentence denotes Sensitivity, specificity, PPV and NPV for TVU in the whole cohort were 33.3, 85.8, 0.6 and 99.8%, respectively.
TextSentencer_T22 1520-1611 Sentence denotes For high-risk individuals, the figures for TVU were 33.3, 84.5, 1.1 and 99.6, respectively.
TextSentencer_T23 1612-1808 Sentence denotes Combining both modalities for the whole cohort, the sensitivity, specificity, PPV and NPV were 66.7, 82.9, 1.5 and 99.8% and 50.0, 82.8, 1.3 and 99.7%, respectively, for the high-risk group alone.
TextSentencer_T24 1809-1821 Sentence denotes CONCLUSIONS:
TextSentencer_T25 1822-1920 Sentence denotes Ovarian screening by annual TVU and CA125 is inefficient at detecting early-stage ovarian cancers.
T1 0-135 Sentence denotes Annual surveillance by CA125 and transvaginal ultrasound for ovarian cancer in both high-risk and population risk women is ineffective.
T2 136-146 Sentence denotes OBJECTIVE:
T3 147-260 Sentence denotes To assess the efficacy of annual CA125 and transvaginal ultrasound (TVU) scan as surveillance for ovarian cancer.
T4 261-268 Sentence denotes DESIGN:
T5 269-289 Sentence denotes Retrospective audit.
T6 290-309 Sentence denotes SETTING: NHS Trust.
T7 310-321 Sentence denotes POPULATION:
T8 322-407 Sentence denotes Three hundred and forty-one asymptomatic women enrolled for ovarian cancer screening:
T9 408-627 Sentence denotes 179 were in a high-risk group (>10% lifetime risk of developing ovarian cancer), 77 in a moderate risk group (4-10% lifetime risk of developing ovarian cancer) and 71 in a near population risk group (<4% lifetime risk).
T10 628-636 Sentence denotes METHODS:
T11 637-768 Sentence denotes Retrospective audit of case records, laboratory CA125 results, radiology reports, histology records and local cancer registry data.
T12 769-791 Sentence denotes MAIN OUTCOME MEASURES:
T13 792-838 Sentence denotes Ovarian cancers occurring in study population.
T14 839-990 Sentence denotes Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of TVU, and CA125 as a screening tool for ovarian cancer.
T15 991-999 Sentence denotes RESULTS:
T16 1000-1057 Sentence denotes Four ovarian cancers and one endometrial cancer occurred.
T17 1058-1180 Sentence denotes One ovarian cancer was detected at surveillance, three occurred in women who presented symptomatically between screenings.
T18 1181-1269 Sentence denotes Thirty women underwent exploratory surgery because of abnormal findings at surveillance.
T19 1270-1361 Sentence denotes Two women had cancer (PPV = 6.7%); one had ovarian cancer and the other endometrial cancer.
T20 1362-1407 Sentence denotes Twenty-eight women (93.3%) had no malignancy.
T21 1408-1519 Sentence denotes Sensitivity, specificity, PPV and NPV for TVU in the whole cohort were 33.3, 85.8, 0.6 and 99.8%, respectively.
T22 1520-1611 Sentence denotes For high-risk individuals, the figures for TVU were 33.3, 84.5, 1.1 and 99.6, respectively.
T23 1612-1808 Sentence denotes Combining both modalities for the whole cohort, the sensitivity, specificity, PPV and NPV were 66.7, 82.9, 1.5 and 99.8% and 50.0, 82.8, 1.3 and 99.7%, respectively, for the high-risk group alone.
T24 1809-1821 Sentence denotes CONCLUSIONS:
T25 1822-1920 Sentence denotes Ovarian screening by annual TVU and CA125 is inefficient at detecting early-stage ovarian cancers.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1858-1863 gene:4077 denotes CA125
T1 1904-1919 disease:C0029925 denotes ovarian cancers
T2 1858-1863 gene:4077 denotes CA125
T3 1904-1919 disease:C1140680 denotes ovarian cancers
T4 1858-1863 gene:94025 denotes CA125
T5 1904-1919 disease:C0029925 denotes ovarian cancers
T6 1858-1863 gene:94025 denotes CA125
T7 1904-1919 disease:C1140680 denotes ovarian cancers
R1 T0 T1 associated_with CA125,ovarian cancers
R2 T2 T3 associated_with CA125,ovarian cancers
R3 T4 T5 associated_with CA125,ovarian cancers
R4 T6 T7 associated_with CA125,ovarian cancers

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 245-259 HP_0100615 denotes ovarian cancer
T2 253-259 HP_0002664 denotes cancer
T1 245-259 HP_0100615 denotes ovarian cancer
T2 253-259 HP_0002664 denotes cancer

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
17903229-0#23#28#gene94025 23-28 gene94025 denotes CA125
17903229-0#23#28#gene4077 23-28 gene4077 denotes CA125
17903229-0#61#75#diseaseC0029925 61-75 diseaseC0029925 denotes ovarian cancer
17903229-0#61#75#diseaseC1140680 61-75 diseaseC1140680 denotes ovarian cancer
17903229-0#61#75#diseaseC0029925 61-75 diseaseC0029925 denotes ovarian cancer
17903229-0#61#75#diseaseC1140680 61-75 diseaseC1140680 denotes ovarian cancer
23#28#gene9402561#75#diseaseC0029925 17903229-0#23#28#gene94025 17903229-0#61#75#diseaseC0029925 associated_with CA125,ovarian cancer
23#28#gene9402561#75#diseaseC1140680 17903229-0#23#28#gene94025 17903229-0#61#75#diseaseC1140680 associated_with CA125,ovarian cancer
23#28#gene9402561#75#diseaseC0029925 17903229-0#23#28#gene94025 17903229-0#61#75#diseaseC0029925 associated_with CA125,ovarian cancer
23#28#gene9402561#75#diseaseC1140680 17903229-0#23#28#gene94025 17903229-0#61#75#diseaseC1140680 associated_with CA125,ovarian cancer
23#28#gene407761#75#diseaseC0029925 17903229-0#23#28#gene4077 17903229-0#61#75#diseaseC0029925 associated_with CA125,ovarian cancer
23#28#gene407761#75#diseaseC1140680 17903229-0#23#28#gene4077 17903229-0#61#75#diseaseC1140680 associated_with CA125,ovarian cancer
23#28#gene407761#75#diseaseC0029925 17903229-0#23#28#gene4077 17903229-0#61#75#diseaseC0029925 associated_with CA125,ovarian cancer
23#28#gene407761#75#diseaseC1140680 17903229-0#23#28#gene4077 17903229-0#61#75#diseaseC1140680 associated_with CA125,ovarian cancer

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2614 23-28 gene:94025 denotes CA125
T2615 61-75 disease:C0029925 denotes ovarian cancer
R1 T2614 T2615 associated_with CA125,ovarian cancer
R2 T2614 T2615 associated_with CA125,ovarian cancer
R3 T2614 T2615 associated_with CA125,ovarian cancer
R4 T2614 T2615 associated_with CA125,ovarian cancer