> top > docs > PubMed:17884841 > annotations

PubMed:17884841 JSONTXT

Annnotations TAB JSON ListView MergeView

Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 445-459 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T2 461-467 https://glytoucan.org/Structures/Glycans/G00054MO denotes SLe(x)
T3 865-871 https://glytoucan.org/Structures/Glycans/G00054MO denotes SLe(x)

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 445-459 Glycan_Motif denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T2 452-459 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T4 461-467 Glycan_Motif denotes SLe(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T5 865-871 Glycan_Motif denotes SLe(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO

LitCoin-PubTator-for-Tuning

Id Subject Object Predicate Lexical cue tao:has_database_id
1 0-14 DiseaseOrPhenotypicFeature denotes Ovarian cancer MESH:D010051
17 97-111 DiseaseOrPhenotypicFeature denotes Ovarian cancer MESH:D010051
18 138-144 DiseaseOrPhenotypicFeature denotes cancer MESH:D009369
19 148-153 OrganismTaxon denotes women Tax:9606
20 251-259 OrganismTaxon denotes patients Tax:9606
21 274-288 DiseaseOrPhenotypicFeature denotes ovarian cancer MESH:D010051
22 427-434 ChemicalEntity denotes glycans MESH:D011134
23 436-439 GeneOrGeneProduct denotes FA2 Gene:2187
24 722-733 GeneOrGeneProduct denotes haptoglobin Gene:3240
25 765-788 GeneOrGeneProduct denotes alpha1-antichymotrypsin Gene:12
26 794-802 OrganismTaxon denotes patients Tax:9606
27 920-928 OrganismTaxon denotes patients Tax:9606
28 958-961 GeneOrGeneProduct denotes FA2 Gene:2187
29 1000-1005 GeneOrGeneProduct denotes CA125 Gene:94025
30 1270-1284 DiseaseOrPhenotypicFeature denotes ovarian cancer MESH:D010051
31 1289-1302 DiseaseOrPhenotypicFeature denotes benign tumors MESH:D009369

LitCoin-Disease-Tuning-1

Id Subject Object Predicate Lexical cue ID:
T1 0-14 DiseaseOrPhenotypicFeature denotes Ovarian cancer D010051
T2 97-111 DiseaseOrPhenotypicFeature denotes Ovarian cancer D010051
T3 138-144 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 274-288 DiseaseOrPhenotypicFeature denotes ovarian cancer D010051
T5 318-325 DiseaseOrPhenotypicFeature denotes disease D004194
T6 1270-1284 DiseaseOrPhenotypicFeature denotes ovarian cancer D010051
T7 1296-1302 DiseaseOrPhenotypicFeature denotes tumors DISEASE|D009369

LitEisuke

Id Subject Object Predicate Lexical cue #label
T1 0-14 DiseaseOrPhenotypicFeature denotes Ovarian cancer D010051
T2 97-111 DiseaseOrPhenotypicFeature denotes Ovarian cancer D010051
T3 138-144 DiseaseOrPhenotypicFeature denotes cancer D009369
T4 274-288 DiseaseOrPhenotypicFeature denotes ovarian cancer D010051
T5 1270-1284 DiseaseOrPhenotypicFeature denotes ovarian cancer D010051
T6 1296-1302 DiseaseOrPhenotypicFeature denotes tumors D009369

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 445-459 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
T2 452-459 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
TextSentencer_T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
TextSentencer_T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
TextSentencer_T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
TextSentencer_T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
TextSentencer_T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
TextSentencer_T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
TextSentencer_T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
TextSentencer_T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.
T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.
T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 445-459 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T2 452-459 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T3 452-459 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T4 461-467 https://glytoucan.org/Structures/Glycans/G00054MO denotes SLe(x)
T5 865-871 https://glytoucan.org/Structures/Glycans/G00054MO denotes SLe(x)

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 97-111 HP_0100615 denotes Ovarian cancer
T2 105-111 HP_0002664 denotes cancer
T3 138-144 HP_0002664 denotes cancer
T4 274-288 HP_0100615 denotes ovarian cancer
T5 282-288 HP_0002664 denotes cancer
T6 1270-1284 HP_0100615 denotes ovarian cancer
T7 1278-1284 HP_0002664 denotes cancer
T8 1296-1302 HP_0002664 denotes tumors

uniprot-human

Id Subject Object Predicate Lexical cue
T1 683-685 http://www.uniprot.org/uniprot/Q92686 denotes ng
T2 722-733 http://www.uniprot.org/uniprot/Q9UC67 denotes haptoglobin
T3 1000-1005 http://www.uniprot.org/uniprot/Q8WXI7 denotes CA125

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 683-685 http://www.uniprot.org/uniprot/P60761 denotes ng
T2 722-733 http://www.uniprot.org/uniprot/Q61646 denotes haptoglobin

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 8-14 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T2 105-111 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T3 138-144 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T4 282-288 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T5 1278-1284 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer

GO-BP

Id Subject Object Predicate Lexical cue
T1 45-58 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T2 595-608 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 326-338 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T4 390-401 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T5 445-451 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T6 544-553 http://purl.obolibrary.org/obo/GO_0032502 denotes developed
T7 595-619 http://purl.obolibrary.org/obo/GO_0006486 denotes glycosylation of protein
T8 1121-1132 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitivity

GO-CC

Id Subject Object Predicate Lexical cue
T1 385-389 http://purl.obolibrary.org/obo/GO_0019013 denotes core

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 187-192 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale
T2 234-239 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T3 1224-1229 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 445-457 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl Lewis
T2 445-459 http://rdf.glycoinfo.org/glycan/G00054MO denotes sialyl Lewis x
T3 452-457 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T4 452-459 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 452-459 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T2 445-457 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis
PD-GlycoEpitope-B_T3 445-459 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 234-239 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T2 994-999 http://purl.obolibrary.org/obo/UBERON_0001977 denotes Serum
PD-UBERON-AE-B_T3 1224-1229 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T4 187-192 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 0-14 Disease denotes Ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T2 97-111 Disease denotes Ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T3 138-144 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T4 274-288 Disease denotes ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T5 436-439 Disease denotes FA2 http://purl.obolibrary.org/obo/MONDO_0010351
T6 958-961 Disease denotes FA2 http://purl.obolibrary.org/obo/MONDO_0010351
T7 1270-1284 Disease denotes ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T8 1289-1302 Disease denotes benign tumors http://purl.obolibrary.org/obo/MONDO_0005165

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 0-14 Phenotype denotes Ovarian cancer HP:0100615
T2 97-111 Phenotype denotes Ovarian cancer HP:0100615
T3 138-144 Phenotype denotes cancer HP:0002664
T4 274-288 Phenotype denotes ovarian cancer HP:0100615
T5 461-464 Phenotype denotes SLe HP:0002725
T6 865-868 Phenotype denotes SLe HP:0002725
T7 1270-1284 Phenotype denotes ovarian cancer HP:0100615

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 445-459 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 0-14 Phenotype denotes Ovarian cancer HP:0100615
T2 97-111 Phenotype denotes Ovarian cancer HP:0100615
T3 138-144 Phenotype denotes cancer HP:0002664
T4 274-288 Phenotype denotes ovarian cancer HP:0100615
T5 1270-1284 Phenotype denotes ovarian cancer HP:0100615

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 0-14 Disease denotes Ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T2 97-111 Disease denotes Ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T3 138-144 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T4 274-288 Disease denotes ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T5 436-439 Disease denotes FA2 http://purl.obolibrary.org/obo/MONDO_0010351
T6 958-961 Disease denotes FA2 http://purl.obolibrary.org/obo/MONDO_0010351
T7 1270-1284 Disease denotes ovarian cancer http://purl.obolibrary.org/obo/MONDO_0008170
T8 1289-1302 Disease denotes benign tumors http://purl.obolibrary.org/obo/MONDO_0005165

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 187-192 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 651-656 Body_part denotes spots http://purl.obolibrary.org/obo/UBERON_2002283

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
TextSentencer_T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
TextSentencer_T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
TextSentencer_T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
TextSentencer_T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
TextSentencer_T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
TextSentencer_T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
TextSentencer_T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
TextSentencer_T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.
T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.
T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-96 Sentence denotes Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
T2 97-175 Sentence denotes Ovarian cancer is the fourth most common cancer in women in the Western world.
T3 176-339 Sentence denotes In a pilot scale study, we highlight changes in the total serum glycome of patients with advanced ovarian cancer that might shed insight into disease pathogenesis.
T4 340-469 Sentence denotes These changes include increases in levels of core fucosylated, agalactosyl biantennary glycans (FA2) and sialyl Lewis x (SLe(x)).
T5 470-695 Sentence denotes To investigate further which proteins contribute to these alterations, we developed technology to analyze simultaneously the glycosylation of protein glycoforms contained in single spots excised from a 2D gel (<1 ng protein).
T6 696-872 Sentence denotes The acute-phase proteins, haptoglobin, alpha1-acid glycoprotein, and alpha1-antichymotrypsin from patients contained elevated levels of subsets of glycoforms containing SLe(x).
T7 873-993 Sentence denotes We also established that IgG heavy chains from patients contained twice the level of FA2 compared with healthy controls.
T8 994-1149 Sentence denotes Serum CA125 is the only biomarker that is used routinely, and there is a need for complementary markers that will improve both sensitivity and specificity.
T9 1150-1426 Sentence denotes There was some preliminary indication that combinations of changes in the serum glycome might improve the separation of ovarian cancer and benign tumors; however, a larger study using data receiver operating characteristic curves will be required to draw any firm conclusions.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue glycosmos_id image
T1 445-459 Glycan denotes sialyl Lewis x https://glycosmos.org/glycans/show/G00054MO https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 445-459 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 445-459 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 187-192 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 651-656 Body_part denotes spots http://purl.obolibrary.org/obo/UBERON_2002283