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Inflammaging

Id Subject Object Predicate Lexical cue
T3 0-1375 Sentence denotes Supporting evidence includes the following: [1] expression of constitutive COX-2-catalyzed prostaglandin biosynthesis is induced by most cancer-causing agents including tobacco smoke and its components (polycylic aromatic amines, heterocyclic amines, nitrosamines), essential polyunsaturated fatty acids (unconjugated linoleic acid), mitogens, growth factors, proinflammatory cytokines, microbial agents, tumor promoters, and other epigenetic factors, [2] COX-2 expression is a characteristic feature of all premalignant neoplasms, [3] COX-2 expression is a characteristic feature of all malignant neoplasms, and expression intensifies with stage at detection and cancer progression and metastasis, [4] all essential features of carcinogenesis (mutagenesis, mitogenesis, angiogenesis, reduced apoptosis, metastasis, and immunosuppression) are linked to COX-2-driven prostaglandin (PGE-2) biosynthesis, [5] animal studies show that COX-2 up-regulation (in the absence of genetic mutations) is sufficient to stimulate the transformation of normal cells to invasive cancer and metastatic disease, [6] non-selective COX-2 inhibitors, such as aspirin and ibuprofen, reduce the risk of human cancer and precancerous lesions, and [7] selective COX-2 inhibitors, such as celecoxib, reduce the risk of human cancer and precancerous lesions at all anatomic sites thus far investigated.
T3 0-1375 Sentence denotes Supporting evidence includes the following: [1] expression of constitutive COX-2-catalyzed prostaglandin biosynthesis is induced by most cancer-causing agents including tobacco smoke and its components (polycylic aromatic amines, heterocyclic amines, nitrosamines), essential polyunsaturated fatty acids (unconjugated linoleic acid), mitogens, growth factors, proinflammatory cytokines, microbial agents, tumor promoters, and other epigenetic factors, [2] COX-2 expression is a characteristic feature of all premalignant neoplasms, [3] COX-2 expression is a characteristic feature of all malignant neoplasms, and expression intensifies with stage at detection and cancer progression and metastasis, [4] all essential features of carcinogenesis (mutagenesis, mitogenesis, angiogenesis, reduced apoptosis, metastasis, and immunosuppression) are linked to COX-2-driven prostaglandin (PGE-2) biosynthesis, [5] animal studies show that COX-2 up-regulation (in the absence of genetic mutations) is sufficient to stimulate the transformation of normal cells to invasive cancer and metastatic disease, [6] non-selective COX-2 inhibitors, such as aspirin and ibuprofen, reduce the risk of human cancer and precancerous lesions, and [7] selective COX-2 inhibitors, such as celecoxib, reduce the risk of human cancer and precancerous lesions at all anatomic sites thus far investigated.

DisGeNET

Id Subject Object Predicate Lexical cue
T12 1237-1242 gene:5743 denotes COX-2
T13 1310-1330 disease:C0940937 denotes precancerous lesions
T14 1237-1242 gene:4513 denotes COX-2
T15 1310-1330 disease:C0940937 denotes precancerous lesions
T16 1237-1242 gene:5743 denotes COX-2
T17 1197-1217 disease:C0940937 denotes precancerous lesions
T18 1237-1242 gene:4513 denotes COX-2
T19 1197-1217 disease:C0940937 denotes precancerous lesions
T20 1237-1242 gene:5743 denotes COX-2
T21 729-743 disease:C0596263 denotes carcinogenesis
T22 1237-1242 gene:4513 denotes COX-2
T23 729-743 disease:C0596263 denotes carcinogenesis
T24 1237-1242 gene:5743 denotes COX-2
T25 687-697 disease:C2939420 denotes metastasis
T26 1237-1242 gene:5743 denotes COX-2
T27 687-697 disease:C0027627 denotes metastasis
T28 1237-1242 gene:4513 denotes COX-2
T29 687-697 disease:C2939420 denotes metastasis
T30 1237-1242 gene:4513 denotes COX-2
T31 687-697 disease:C0027627 denotes metastasis
T32 1237-1242 gene:5743 denotes COX-2
T33 664-682 disease:C0178874 denotes cancer progression
T34 1237-1242 gene:4513 denotes COX-2
T35 664-682 disease:C0178874 denotes cancer progression
T36 1237-1242 gene:5743 denotes COX-2
T37 588-607 disease:C0006826 denotes malignant neoplasms
T38 1237-1242 gene:4513 denotes COX-2
T39 588-607 disease:C0006826 denotes malignant neoplasms
T40 1237-1242 gene:5743 denotes COX-2
T41 508-520 disease:C0032927 denotes premalignant
T42 1237-1242 gene:4513 denotes COX-2
T43 508-520 disease:C0032927 denotes premalignant
T44 1237-1242 gene:5743 denotes COX-2
T45 137-143 disease:C1306459 denotes cancer
T46 1237-1242 gene:5743 denotes COX-2
T47 137-143 disease:C0006826 denotes cancer
T48 1237-1242 gene:4513 denotes COX-2
T49 137-143 disease:C1306459 denotes cancer
T50 1237-1242 gene:4513 denotes COX-2
T51 137-143 disease:C0006826 denotes cancer
T52 1112-1117 gene:5743 denotes COX-2
T53 1310-1330 disease:C0940937 denotes precancerous lesions
T54 1112-1117 gene:4513 denotes COX-2
T55 1310-1330 disease:C0940937 denotes precancerous lesions
T56 1112-1117 gene:5743 denotes COX-2
T57 1197-1217 disease:C0940937 denotes precancerous lesions
T58 1112-1117 gene:4513 denotes COX-2
T59 1197-1217 disease:C0940937 denotes precancerous lesions
T60 1112-1117 gene:5743 denotes COX-2
T61 729-743 disease:C0596263 denotes carcinogenesis
T62 1112-1117 gene:4513 denotes COX-2
T63 729-743 disease:C0596263 denotes carcinogenesis
T64 1112-1117 gene:5743 denotes COX-2
T65 687-697 disease:C2939420 denotes metastasis
T66 1112-1117 gene:5743 denotes COX-2
T67 687-697 disease:C0027627 denotes metastasis
T68 1112-1117 gene:4513 denotes COX-2
T69 687-697 disease:C2939420 denotes metastasis
T70 1112-1117 gene:4513 denotes COX-2
T71 687-697 disease:C0027627 denotes metastasis
T72 1112-1117 gene:5743 denotes COX-2
T73 664-682 disease:C0178874 denotes cancer progression
T74 1112-1117 gene:4513 denotes COX-2
T75 664-682 disease:C0178874 denotes cancer progression
T76 1112-1117 gene:5743 denotes COX-2
T77 508-520 disease:C0032927 denotes premalignant
T78 1112-1117 gene:4513 denotes COX-2
T79 508-520 disease:C0032927 denotes premalignant
T80 1112-1117 gene:5743 denotes COX-2
T81 137-143 disease:C1306459 denotes cancer
T82 1112-1117 gene:5743 denotes COX-2
T83 137-143 disease:C0006826 denotes cancer
T84 1112-1117 gene:4513 denotes COX-2
T85 137-143 disease:C1306459 denotes cancer
T86 1112-1117 gene:4513 denotes COX-2
T87 137-143 disease:C0006826 denotes cancer
T88 931-936 gene:5743 denotes COX-2
T89 1310-1330 disease:C0940937 denotes precancerous lesions
T90 931-936 gene:4513 denotes COX-2
T91 1310-1330 disease:C0940937 denotes precancerous lesions
T92 931-936 gene:5743 denotes COX-2
T93 1299-1305 disease:C1306459 denotes cancer
T94 931-936 gene:5743 denotes COX-2
T95 1299-1305 disease:C0006826 denotes cancer
T96 931-936 gene:4513 denotes COX-2
T97 1299-1305 disease:C1306459 denotes cancer
T98 931-936 gene:4513 denotes COX-2
T99 1299-1305 disease:C0006826 denotes cancer
T100 931-936 gene:5743 denotes COX-2
T101 1197-1217 disease:C0940937 denotes precancerous lesions
T102 931-936 gene:4513 denotes COX-2
T103 1197-1217 disease:C0940937 denotes precancerous lesions
T104 931-936 gene:5743 denotes COX-2
T105 1074-1092 disease:C2939420 denotes metastatic disease
T106 931-936 gene:5743 denotes COX-2
T107 1074-1092 disease:C0027627 denotes metastatic disease
T108 931-936 gene:4513 denotes COX-2
T109 1074-1092 disease:C2939420 denotes metastatic disease
T110 931-936 gene:4513 denotes COX-2
T111 1074-1092 disease:C0027627 denotes metastatic disease
T112 931-936 gene:5743 denotes COX-2
T113 1054-1069 disease:C0677898 denotes invasive cancer
T114 931-936 gene:4513 denotes COX-2
T115 1054-1069 disease:C0677898 denotes invasive cancer
T116 931-936 gene:5743 denotes COX-2
T117 729-743 disease:C0596263 denotes carcinogenesis
T118 931-936 gene:4513 denotes COX-2
T119 729-743 disease:C0596263 denotes carcinogenesis
T120 931-936 gene:5743 denotes COX-2
T121 508-520 disease:C0032927 denotes premalignant
T122 931-936 gene:4513 denotes COX-2
T123 508-520 disease:C0032927 denotes premalignant
T124 931-936 gene:5743 denotes COX-2
T125 137-143 disease:C1306459 denotes cancer
T126 931-936 gene:5743 denotes COX-2
T127 137-143 disease:C0006826 denotes cancer
T128 931-936 gene:4513 denotes COX-2
T129 137-143 disease:C1306459 denotes cancer
T130 931-936 gene:4513 denotes COX-2
T131 137-143 disease:C0006826 denotes cancer
T132 853-858 gene:5743 denotes COX-2
T133 1310-1330 disease:C0940937 denotes precancerous lesions
T134 853-858 gene:4513 denotes COX-2
T135 1310-1330 disease:C0940937 denotes precancerous lesions
T136 853-858 gene:5743 denotes COX-2
T137 1197-1217 disease:C0940937 denotes precancerous lesions
T138 853-858 gene:4513 denotes COX-2
T139 1197-1217 disease:C0940937 denotes precancerous lesions
T140 853-858 gene:5743 denotes COX-2
T141 1074-1092 disease:C2939420 denotes metastatic disease
T142 853-858 gene:5743 denotes COX-2
T143 1074-1092 disease:C0027627 denotes metastatic disease
T144 853-858 gene:4513 denotes COX-2
T145 1074-1092 disease:C2939420 denotes metastatic disease
T146 853-858 gene:4513 denotes COX-2
T147 1074-1092 disease:C0027627 denotes metastatic disease
T148 853-858 gene:5743 denotes COX-2
T149 729-743 disease:C0596263 denotes carcinogenesis
T150 853-858 gene:4513 denotes COX-2
T151 729-743 disease:C0596263 denotes carcinogenesis
T152 853-858 gene:5743 denotes COX-2
T153 508-520 disease:C0032927 denotes premalignant
T154 853-858 gene:4513 denotes COX-2
T155 508-520 disease:C0032927 denotes premalignant
T156 536-541 gene:5743 denotes COX-2
T157 1310-1330 disease:C0940937 denotes precancerous lesions
T158 536-541 gene:4513 denotes COX-2
T159 1310-1330 disease:C0940937 denotes precancerous lesions
T160 536-541 gene:5743 denotes COX-2
T161 1299-1305 disease:C1306459 denotes cancer
T162 536-541 gene:5743 denotes COX-2
T163 1299-1305 disease:C0006826 denotes cancer
T164 536-541 gene:4513 denotes COX-2
T165 1299-1305 disease:C1306459 denotes cancer
T166 536-541 gene:4513 denotes COX-2
T167 1299-1305 disease:C0006826 denotes cancer
T168 536-541 gene:5743 denotes COX-2
T169 1197-1217 disease:C0940937 denotes precancerous lesions
T170 536-541 gene:4513 denotes COX-2
T171 1197-1217 disease:C0940937 denotes precancerous lesions
T172 536-541 gene:5743 denotes COX-2
T173 1186-1192 disease:C1306459 denotes cancer
T174 536-541 gene:5743 denotes COX-2
T175 1186-1192 disease:C0006826 denotes cancer
T176 536-541 gene:4513 denotes COX-2
T177 1186-1192 disease:C1306459 denotes cancer
T178 536-541 gene:4513 denotes COX-2
T179 1186-1192 disease:C0006826 denotes cancer
T180 536-541 gene:5743 denotes COX-2
T181 1074-1092 disease:C2939420 denotes metastatic disease
T182 536-541 gene:5743 denotes COX-2
T183 1074-1092 disease:C0027627 denotes metastatic disease
T184 536-541 gene:4513 denotes COX-2
T185 1074-1092 disease:C2939420 denotes metastatic disease
T186 536-541 gene:4513 denotes COX-2
T187 1074-1092 disease:C0027627 denotes metastatic disease
T188 536-541 gene:5743 denotes COX-2
T189 1054-1069 disease:C0677898 denotes invasive cancer
T190 536-541 gene:4513 denotes COX-2
T191 1054-1069 disease:C0677898 denotes invasive cancer
T192 536-541 gene:5743 denotes COX-2
T193 729-743 disease:C0596263 denotes carcinogenesis
T194 536-541 gene:4513 denotes COX-2
T195 729-743 disease:C0596263 denotes carcinogenesis
T196 536-541 gene:5743 denotes COX-2
T197 687-697 disease:C2939420 denotes metastasis
T198 536-541 gene:5743 denotes COX-2
T199 687-697 disease:C0027627 denotes metastasis
T200 536-541 gene:4513 denotes COX-2
T201 687-697 disease:C2939420 denotes metastasis
T202 536-541 gene:4513 denotes COX-2
T203 687-697 disease:C0027627 denotes metastasis
T204 536-541 gene:5743 denotes COX-2
T205 664-682 disease:C0178874 denotes cancer progression
T206 536-541 gene:4513 denotes COX-2
T207 664-682 disease:C0178874 denotes cancer progression
T208 536-541 gene:5743 denotes COX-2
T209 588-607 disease:C0006826 denotes malignant neoplasms
T210 536-541 gene:4513 denotes COX-2
T211 588-607 disease:C0006826 denotes malignant neoplasms
T212 536-541 gene:5743 denotes COX-2
T213 137-143 disease:C1306459 denotes cancer
T214 536-541 gene:5743 denotes COX-2
T215 137-143 disease:C0006826 denotes cancer
T216 536-541 gene:4513 denotes COX-2
T217 137-143 disease:C1306459 denotes cancer
T218 536-541 gene:4513 denotes COX-2
T219 137-143 disease:C0006826 denotes cancer
T220 456-461 gene:5743 denotes COX-2
T221 1310-1330 disease:C0940937 denotes precancerous lesions
T222 456-461 gene:4513 denotes COX-2
T223 1310-1330 disease:C0940937 denotes precancerous lesions
T224 456-461 gene:5743 denotes COX-2
T225 1299-1305 disease:C1306459 denotes cancer
T226 456-461 gene:5743 denotes COX-2
T227 1299-1305 disease:C0006826 denotes cancer
T228 456-461 gene:4513 denotes COX-2
T229 1299-1305 disease:C1306459 denotes cancer
T230 456-461 gene:4513 denotes COX-2
T231 1299-1305 disease:C0006826 denotes cancer
T232 456-461 gene:5743 denotes COX-2
T233 1197-1217 disease:C0940937 denotes precancerous lesions
T234 456-461 gene:4513 denotes COX-2
T235 1197-1217 disease:C0940937 denotes precancerous lesions
T236 456-461 gene:5743 denotes COX-2
T237 1186-1192 disease:C1306459 denotes cancer
T238 456-461 gene:5743 denotes COX-2
T239 1186-1192 disease:C0006826 denotes cancer
T240 456-461 gene:4513 denotes COX-2
T241 1186-1192 disease:C1306459 denotes cancer
T242 456-461 gene:4513 denotes COX-2
T243 1186-1192 disease:C0006826 denotes cancer
T244 456-461 gene:5743 denotes COX-2
T245 1074-1092 disease:C2939420 denotes metastatic disease
T246 456-461 gene:5743 denotes COX-2
T247 1074-1092 disease:C0027627 denotes metastatic disease
T248 456-461 gene:4513 denotes COX-2
T249 1074-1092 disease:C2939420 denotes metastatic disease
T250 456-461 gene:4513 denotes COX-2
T251 1074-1092 disease:C0027627 denotes metastatic disease
T252 456-461 gene:5743 denotes COX-2
T253 1054-1069 disease:C0677898 denotes invasive cancer
T254 456-461 gene:4513 denotes COX-2
T255 1054-1069 disease:C0677898 denotes invasive cancer
T256 456-461 gene:5743 denotes COX-2
T257 729-743 disease:C0596263 denotes carcinogenesis
T258 456-461 gene:4513 denotes COX-2
T259 729-743 disease:C0596263 denotes carcinogenesis
T260 456-461 gene:5743 denotes COX-2
T261 687-697 disease:C2939420 denotes metastasis
T262 456-461 gene:5743 denotes COX-2
T263 687-697 disease:C0027627 denotes metastasis
T264 456-461 gene:4513 denotes COX-2
T265 687-697 disease:C2939420 denotes metastasis
T266 456-461 gene:4513 denotes COX-2
T267 687-697 disease:C0027627 denotes metastasis
T268 456-461 gene:5743 denotes COX-2
T269 664-682 disease:C0178874 denotes cancer progression
T270 456-461 gene:4513 denotes COX-2
T271 664-682 disease:C0178874 denotes cancer progression
T272 456-461 gene:5743 denotes COX-2
T273 508-520 disease:C0032927 denotes premalignant
T274 456-461 gene:4513 denotes COX-2
T275 508-520 disease:C0032927 denotes premalignant
T276 456-461 gene:5743 denotes COX-2
T277 137-143 disease:C1306459 denotes cancer
T278 456-461 gene:5743 denotes COX-2
T279 137-143 disease:C0006826 denotes cancer
T280 456-461 gene:4513 denotes COX-2
T281 137-143 disease:C1306459 denotes cancer
T282 456-461 gene:4513 denotes COX-2
T283 137-143 disease:C0006826 denotes cancer
T284 75-80 gene:5743 denotes COX-2
T285 1310-1330 disease:C0940937 denotes precancerous lesions
T286 75-80 gene:4513 denotes COX-2
T287 1310-1330 disease:C0940937 denotes precancerous lesions
T288 75-80 gene:5743 denotes COX-2
T289 1197-1217 disease:C0940937 denotes precancerous lesions
T290 75-80 gene:4513 denotes COX-2
T291 1197-1217 disease:C0940937 denotes precancerous lesions
T292 75-80 gene:5743 denotes COX-2
T293 1074-1092 disease:C2939420 denotes metastatic disease
T294 75-80 gene:5743 denotes COX-2
T295 1074-1092 disease:C0027627 denotes metastatic disease
T296 75-80 gene:4513 denotes COX-2
T297 1074-1092 disease:C2939420 denotes metastatic disease
T298 75-80 gene:4513 denotes COX-2
T299 1074-1092 disease:C0027627 denotes metastatic disease
T300 75-80 gene:5743 denotes COX-2
T301 1054-1069 disease:C0677898 denotes invasive cancer
T302 75-80 gene:4513 denotes COX-2
T303 1054-1069 disease:C0677898 denotes invasive cancer
T304 75-80 gene:5743 denotes COX-2
T305 729-743 disease:C0596263 denotes carcinogenesis
T306 75-80 gene:4513 denotes COX-2
T307 729-743 disease:C0596263 denotes carcinogenesis
T308 75-80 gene:5743 denotes COX-2
T309 687-697 disease:C2939420 denotes metastasis
T310 75-80 gene:5743 denotes COX-2
T311 687-697 disease:C0027627 denotes metastasis
T312 75-80 gene:4513 denotes COX-2
T313 687-697 disease:C2939420 denotes metastasis
T314 75-80 gene:4513 denotes COX-2
T315 687-697 disease:C0027627 denotes metastasis
T316 75-80 gene:5743 denotes COX-2
T317 664-682 disease:C0178874 denotes cancer progression
T318 75-80 gene:4513 denotes COX-2
T319 664-682 disease:C0178874 denotes cancer progression
T320 75-80 gene:5743 denotes COX-2
T321 508-520 disease:C0032927 denotes premalignant
T322 75-80 gene:4513 denotes COX-2
T323 508-520 disease:C0032927 denotes premalignant
T324 75-80 gene:5743 denotes COX-2
T325 137-143 disease:C1306459 denotes cancer
T326 75-80 gene:5743 denotes COX-2
T327 137-143 disease:C0006826 denotes cancer
T328 75-80 gene:4513 denotes COX-2
T329 137-143 disease:C1306459 denotes cancer
T330 75-80 gene:4513 denotes COX-2
T331 137-143 disease:C0006826 denotes cancer
R7 T12 T13 associated_with COX-2,precancerous lesions
R8 T14 T15 associated_with COX-2,precancerous lesions
R9 T16 T17 associated_with COX-2,precancerous lesions
R10 T18 T19 associated_with COX-2,precancerous lesions
R11 T20 T21 associated_with COX-2,carcinogenesis
R12 T22 T23 associated_with COX-2,carcinogenesis
R13 T24 T25 associated_with COX-2,metastasis
R14 T26 T27 associated_with COX-2,metastasis
R15 T28 T29 associated_with COX-2,metastasis
R16 T30 T31 associated_with COX-2,metastasis
R17 T32 T33 associated_with COX-2,cancer progression
R18 T34 T35 associated_with COX-2,cancer progression
R19 T36 T37 associated_with COX-2,malignant neoplasms
R20 T38 T39 associated_with COX-2,malignant neoplasms
R21 T40 T41 associated_with COX-2,premalignant
R22 T42 T43 associated_with COX-2,premalignant
R23 T44 T45 associated_with COX-2,cancer
R24 T46 T47 associated_with COX-2,cancer
R25 T48 T49 associated_with COX-2,cancer
R26 T50 T51 associated_with COX-2,cancer
R27 T52 T53 associated_with COX-2,precancerous lesions
R28 T54 T55 associated_with COX-2,precancerous lesions
R29 T56 T57 associated_with COX-2,precancerous lesions
R30 T58 T59 associated_with COX-2,precancerous lesions
R31 T60 T61 associated_with COX-2,carcinogenesis
R32 T62 T63 associated_with COX-2,carcinogenesis
R33 T64 T65 associated_with COX-2,metastasis
R34 T66 T67 associated_with COX-2,metastasis
R35 T68 T69 associated_with COX-2,metastasis
R36 T70 T71 associated_with COX-2,metastasis
R37 T72 T73 associated_with COX-2,cancer progression
R38 T74 T75 associated_with COX-2,cancer progression
R39 T76 T77 associated_with COX-2,premalignant
R40 T78 T79 associated_with COX-2,premalignant
R41 T80 T81 associated_with COX-2,cancer
R42 T82 T83 associated_with COX-2,cancer
R43 T84 T85 associated_with COX-2,cancer
R44 T86 T87 associated_with COX-2,cancer
R45 T88 T89 associated_with COX-2,precancerous lesions
R46 T90 T91 associated_with COX-2,precancerous lesions
R47 T92 T93 associated_with COX-2,cancer
R48 T94 T95 associated_with COX-2,cancer
R49 T96 T97 associated_with COX-2,cancer
R50 T98 T99 associated_with COX-2,cancer
R51 T100 T101 associated_with COX-2,precancerous lesions
R52 T102 T103 associated_with COX-2,precancerous lesions
R53 T104 T105 associated_with COX-2,metastatic disease
R54 T106 T107 associated_with COX-2,metastatic disease
R55 T108 T109 associated_with COX-2,metastatic disease
R56 T110 T111 associated_with COX-2,metastatic disease
R57 T112 T113 associated_with COX-2,invasive cancer
R58 T114 T115 associated_with COX-2,invasive cancer
R59 T116 T117 associated_with COX-2,carcinogenesis
R60 T118 T119 associated_with COX-2,carcinogenesis
R61 T120 T121 associated_with COX-2,premalignant
R62 T122 T123 associated_with COX-2,premalignant
R63 T124 T125 associated_with COX-2,cancer
R64 T126 T127 associated_with COX-2,cancer
R65 T128 T129 associated_with COX-2,cancer
R66 T130 T131 associated_with COX-2,cancer
R67 T132 T133 associated_with COX-2,precancerous lesions
R68 T134 T135 associated_with COX-2,precancerous lesions
R69 T136 T137 associated_with COX-2,precancerous lesions
R70 T138 T139 associated_with COX-2,precancerous lesions
R71 T140 T141 associated_with COX-2,metastatic disease
R72 T142 T143 associated_with COX-2,metastatic disease
R73 T144 T145 associated_with COX-2,metastatic disease
R74 T146 T147 associated_with COX-2,metastatic disease
R75 T148 T149 associated_with COX-2,carcinogenesis
R76 T150 T151 associated_with COX-2,carcinogenesis
R77 T152 T153 associated_with COX-2,premalignant
R78 T154 T155 associated_with COX-2,premalignant
R79 T156 T157 associated_with COX-2,precancerous lesions
R80 T158 T159 associated_with COX-2,precancerous lesions
R81 T160 T161 associated_with COX-2,cancer
R82 T162 T163 associated_with COX-2,cancer
R83 T164 T165 associated_with COX-2,cancer
R84 T166 T167 associated_with COX-2,cancer
R85 T168 T169 associated_with COX-2,precancerous lesions
R86 T170 T171 associated_with COX-2,precancerous lesions
R87 T172 T173 associated_with COX-2,cancer
R88 T174 T175 associated_with COX-2,cancer
R89 T176 T177 associated_with COX-2,cancer
R90 T178 T179 associated_with COX-2,cancer
R91 T180 T181 associated_with COX-2,metastatic disease
R92 T182 T183 associated_with COX-2,metastatic disease
R93 T184 T185 associated_with COX-2,metastatic disease
R94 T186 T187 associated_with COX-2,metastatic disease
R95 T188 T189 associated_with COX-2,invasive cancer
R96 T190 T191 associated_with COX-2,invasive cancer
R97 T192 T193 associated_with COX-2,carcinogenesis
R98 T194 T195 associated_with COX-2,carcinogenesis
R99 T196 T197 associated_with COX-2,metastasis
R100 T198 T199 associated_with COX-2,metastasis
R101 T200 T201 associated_with COX-2,metastasis
R102 T202 T203 associated_with COX-2,metastasis
R103 T204 T205 associated_with COX-2,cancer progression
R104 T206 T207 associated_with COX-2,cancer progression
R105 T208 T209 associated_with COX-2,malignant neoplasms
R106 T210 T211 associated_with COX-2,malignant neoplasms
R107 T212 T213 associated_with COX-2,cancer
R108 T214 T215 associated_with COX-2,cancer
R109 T216 T217 associated_with COX-2,cancer
R110 T218 T219 associated_with COX-2,cancer
R111 T220 T221 associated_with COX-2,precancerous lesions
R112 T222 T223 associated_with COX-2,precancerous lesions
R113 T224 T225 associated_with COX-2,cancer
R114 T226 T227 associated_with COX-2,cancer
R115 T228 T229 associated_with COX-2,cancer
R116 T230 T231 associated_with COX-2,cancer
R117 T232 T233 associated_with COX-2,precancerous lesions
R118 T234 T235 associated_with COX-2,precancerous lesions
R119 T236 T237 associated_with COX-2,cancer
R120 T238 T239 associated_with COX-2,cancer
R121 T240 T241 associated_with COX-2,cancer
R122 T242 T243 associated_with COX-2,cancer
R123 T244 T245 associated_with COX-2,metastatic disease
R124 T246 T247 associated_with COX-2,metastatic disease
R125 T248 T249 associated_with COX-2,metastatic disease
R126 T250 T251 associated_with COX-2,metastatic disease
R127 T252 T253 associated_with COX-2,invasive cancer
R128 T254 T255 associated_with COX-2,invasive cancer
R129 T256 T257 associated_with COX-2,carcinogenesis
R130 T258 T259 associated_with COX-2,carcinogenesis
R131 T260 T261 associated_with COX-2,metastasis
R132 T262 T263 associated_with COX-2,metastasis
R133 T264 T265 associated_with COX-2,metastasis
R134 T266 T267 associated_with COX-2,metastasis
R135 T268 T269 associated_with COX-2,cancer progression
R136 T270 T271 associated_with COX-2,cancer progression
R137 T272 T273 associated_with COX-2,premalignant
R138 T274 T275 associated_with COX-2,premalignant
R139 T276 T277 associated_with COX-2,cancer
R140 T278 T279 associated_with COX-2,cancer
R141 T280 T281 associated_with COX-2,cancer
R142 T282 T283 associated_with COX-2,cancer
R143 T284 T285 associated_with COX-2,precancerous lesions
R144 T286 T287 associated_with COX-2,precancerous lesions
R145 T288 T289 associated_with COX-2,precancerous lesions
R146 T290 T291 associated_with COX-2,precancerous lesions
R147 T292 T293 associated_with COX-2,metastatic disease
R148 T294 T295 associated_with COX-2,metastatic disease
R149 T296 T297 associated_with COX-2,metastatic disease
R150 T298 T299 associated_with COX-2,metastatic disease
R151 T300 T301 associated_with COX-2,invasive cancer
R152 T302 T303 associated_with COX-2,invasive cancer
R153 T304 T305 associated_with COX-2,carcinogenesis
R154 T306 T307 associated_with COX-2,carcinogenesis
R155 T308 T309 associated_with COX-2,metastasis
R156 T310 T311 associated_with COX-2,metastasis
R157 T312 T313 associated_with COX-2,metastasis
R158 T314 T315 associated_with COX-2,metastasis
R159 T316 T317 associated_with COX-2,cancer progression
R160 T318 T319 associated_with COX-2,cancer progression
R161 T320 T321 associated_with COX-2,premalignant
R162 T322 T323 associated_with COX-2,premalignant
R163 T324 T325 associated_with COX-2,cancer
R164 T326 T327 associated_with COX-2,cancer
R165 T328 T329 associated_with COX-2,cancer
R166 T330 T331 associated_with COX-2,cancer

PubmedHPO

Id Subject Object Predicate Lexical cue
T2 137-143 HP_0002664 denotes cancer
T3 405-410 HP_0002664 denotes tumor
T4 521-530 HP_0002664 denotes neoplasms
T5 598-607 HP_0002664 denotes neoplasms
T6 664-670 HP_0002664 denotes cancer
T7 1063-1069 HP_0002664 denotes cancer
T8 1186-1192 HP_0002664 denotes cancer
T9 1299-1305 HP_0002664 denotes cancer

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
17612047-2#75#80#gene5743 75-80 gene5743 denotes COX-2
17612047-2#456#461#gene5743 456-461 gene5743 denotes COX-2
17612047-2#536#541#gene5743 536-541 gene5743 denotes COX-2
17612047-2#853#858#gene5743 853-858 gene5743 denotes COX-2
17612047-2#931#936#gene5743 931-936 gene5743 denotes COX-2
17612047-2#1237#1242#gene5743 1237-1242 gene5743 denotes COX-2
17612047-2#508#520#diseaseC0032927 508-520 diseaseC0032927 denotes premalignant
17612047-2#687#697#diseaseC0027627 687-697 diseaseC0027627 denotes metastasis
17612047-2#1074#1092#diseaseC0027627 1074-1092 diseaseC0027627 denotes metastatic disease
17612047-2#508#520#diseaseC0032927 508-520 diseaseC0032927 denotes premalignant
17612047-2#687#697#diseaseC0027627 687-697 diseaseC0027627 denotes metastasis
17612047-2#1074#1092#diseaseC0027627 1074-1092 diseaseC0027627 denotes metastatic disease
17612047-2#687#697#diseaseC0027627 687-697 diseaseC0027627 denotes metastasis
17612047-2#1074#1092#diseaseC0027627 1074-1092 diseaseC0027627 denotes metastatic disease
17612047-2#508#520#diseaseC0032927 508-520 diseaseC0032927 denotes premalignant
17612047-2#687#697#diseaseC0027627 687-697 diseaseC0027627 denotes metastasis
17612047-2#1074#1092#diseaseC0027627 1074-1092 diseaseC0027627 denotes metastatic disease
17612047-2#508#520#diseaseC0032927 508-520 diseaseC0032927 denotes premalignant
17612047-2#687#697#diseaseC0027627 687-697 diseaseC0027627 denotes metastasis
75#80#gene5743508#520#diseaseC0032927 17612047-2#75#80#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
75#80#gene5743687#697#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
75#80#gene57431074#1092#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
75#80#gene5743508#520#diseaseC0032927 17612047-2#75#80#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
75#80#gene5743687#697#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
75#80#gene57431074#1092#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
75#80#gene5743687#697#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
75#80#gene57431074#1092#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
75#80#gene5743508#520#diseaseC0032927 17612047-2#75#80#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
75#80#gene5743687#697#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
75#80#gene57431074#1092#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
75#80#gene5743508#520#diseaseC0032927 17612047-2#75#80#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
75#80#gene5743687#697#diseaseC0027627 17612047-2#75#80#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
456#461#gene5743508#520#diseaseC0032927 17612047-2#456#461#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
456#461#gene5743687#697#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
456#461#gene57431074#1092#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
456#461#gene5743508#520#diseaseC0032927 17612047-2#456#461#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
456#461#gene5743687#697#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
456#461#gene57431074#1092#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
456#461#gene5743687#697#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
456#461#gene57431074#1092#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
456#461#gene5743508#520#diseaseC0032927 17612047-2#456#461#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
456#461#gene5743687#697#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
456#461#gene57431074#1092#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
456#461#gene5743508#520#diseaseC0032927 17612047-2#456#461#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
456#461#gene5743687#697#diseaseC0027627 17612047-2#456#461#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
536#541#gene5743508#520#diseaseC0032927 17612047-2#536#541#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
536#541#gene5743687#697#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
536#541#gene57431074#1092#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
536#541#gene5743508#520#diseaseC0032927 17612047-2#536#541#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
536#541#gene5743687#697#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
536#541#gene57431074#1092#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
536#541#gene5743687#697#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
536#541#gene57431074#1092#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
536#541#gene5743508#520#diseaseC0032927 17612047-2#536#541#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
536#541#gene5743687#697#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
536#541#gene57431074#1092#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
536#541#gene5743508#520#diseaseC0032927 17612047-2#536#541#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
536#541#gene5743687#697#diseaseC0027627 17612047-2#536#541#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
853#858#gene5743508#520#diseaseC0032927 17612047-2#853#858#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
853#858#gene5743687#697#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
853#858#gene57431074#1092#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
853#858#gene5743508#520#diseaseC0032927 17612047-2#853#858#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
853#858#gene5743687#697#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
853#858#gene57431074#1092#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
853#858#gene5743687#697#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
853#858#gene57431074#1092#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
853#858#gene5743508#520#diseaseC0032927 17612047-2#853#858#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
853#858#gene5743687#697#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
853#858#gene57431074#1092#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
853#858#gene5743508#520#diseaseC0032927 17612047-2#853#858#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
853#858#gene5743687#697#diseaseC0027627 17612047-2#853#858#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
931#936#gene5743508#520#diseaseC0032927 17612047-2#931#936#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
931#936#gene5743687#697#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
931#936#gene57431074#1092#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
931#936#gene5743508#520#diseaseC0032927 17612047-2#931#936#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
931#936#gene5743687#697#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
931#936#gene57431074#1092#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
931#936#gene5743687#697#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
931#936#gene57431074#1092#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
931#936#gene5743508#520#diseaseC0032927 17612047-2#931#936#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
931#936#gene5743687#697#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
931#936#gene57431074#1092#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
931#936#gene5743508#520#diseaseC0032927 17612047-2#931#936#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
931#936#gene5743687#697#diseaseC0027627 17612047-2#931#936#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
1237#1242#gene5743508#520#diseaseC0032927 17612047-2#1237#1242#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
1237#1242#gene5743687#697#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
1237#1242#gene57431074#1092#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
1237#1242#gene5743508#520#diseaseC0032927 17612047-2#1237#1242#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
1237#1242#gene5743687#697#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
1237#1242#gene57431074#1092#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
1237#1242#gene5743687#697#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
1237#1242#gene57431074#1092#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
1237#1242#gene5743508#520#diseaseC0032927 17612047-2#1237#1242#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
1237#1242#gene5743687#697#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis
1237#1242#gene57431074#1092#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#1074#1092#diseaseC0027627 associated_with COX-2,metastatic disease
1237#1242#gene5743508#520#diseaseC0032927 17612047-2#1237#1242#gene5743 17612047-2#508#520#diseaseC0032927 associated_with COX-2,premalignant
1237#1242#gene5743687#697#diseaseC0027627 17612047-2#1237#1242#gene5743 17612047-2#687#697#diseaseC0027627 associated_with COX-2,metastasis