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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-126 Sentence denotes Kinetics of Hyal-1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction.
TextSentencer_T2 127-322 Sentence denotes The availability of recombinant expression systems for the production of purified human hyaluronidases PH-20 and Hyal-1 facilitated the first detailed analysis of the enzymatic reaction products.
TextSentencer_T3 323-588 Sentence denotes The human recombinant enzymes, both expressed by Drosophila Schneider-2 (DS-2) cells, were compared to bovine testicular hyaluronidase (BTH), a commercially available hyaluronidase preparation, which has long been considered a prototype of mammalian hyaluronidases.
TextSentencer_T4 589-721 Sentence denotes The conversion of low molecular weight hyaluronic acid (HA) fragments was detected by a capillary zone electrophoresis (CZE) method.
TextSentencer_T5 722-881 Sentence denotes Surprisingly, the HA hexasaccharide, which is generally accepted to be the minimum substrate of BTH, was not a substrate of recombinant human PH-20 and Hyal-1.
TextSentencer_T6 882-1019 Sentence denotes However, HA octasaccharide was converted efficiently by both enzymes, thus representing the minimum substrate for human PH-20 and Hyal-1.
TextSentencer_T7 1020-1161 Sentence denotes Additionally, BTH was shown to catabolize the HA hexasaccharide at pH 4.0 mainly by hydrolysis, while at pH 6.0 transglycosylation prevailed.
TextSentencer_T8 1162-1260 Sentence denotes Human PH-20 was found to catalyze both hydrolysis and transglycosylation of the HA octasaccharide.
TextSentencer_T9 1261-1445 Sentence denotes On the contrary, human Hyal-1 converted the HA octasaccharide mainly by hydrolysis with transglycosylation products occurring only at high substrate concentrations (> or = 500 microM).
TextSentencer_T10 1446-1551 Sentence denotes The differences between the hyaluronidase subtypes and isoenzymes were much more prominent than expected.
TextSentencer_T11 1552-1695 Sentence denotes Obviously, the different hyaluronidase subtypes have evolved into very specialized enzymes with respect to their catalytic mechanism of action.
T1 0-126 Sentence denotes Kinetics of Hyal-1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction.
T2 127-322 Sentence denotes The availability of recombinant expression systems for the production of purified human hyaluronidases PH-20 and Hyal-1 facilitated the first detailed analysis of the enzymatic reaction products.
T3 323-588 Sentence denotes The human recombinant enzymes, both expressed by Drosophila Schneider-2 (DS-2) cells, were compared to bovine testicular hyaluronidase (BTH), a commercially available hyaluronidase preparation, which has long been considered a prototype of mammalian hyaluronidases.
T4 589-721 Sentence denotes The conversion of low molecular weight hyaluronic acid (HA) fragments was detected by a capillary zone electrophoresis (CZE) method.
T5 722-881 Sentence denotes Surprisingly, the HA hexasaccharide, which is generally accepted to be the minimum substrate of BTH, was not a substrate of recombinant human PH-20 and Hyal-1.
T6 882-1019 Sentence denotes However, HA octasaccharide was converted efficiently by both enzymes, thus representing the minimum substrate for human PH-20 and Hyal-1.
T7 1020-1161 Sentence denotes Additionally, BTH was shown to catabolize the HA hexasaccharide at pH 4.0 mainly by hydrolysis, while at pH 6.0 transglycosylation prevailed.
T8 1162-1260 Sentence denotes Human PH-20 was found to catalyze both hydrolysis and transglycosylation of the HA octasaccharide.
T9 1261-1445 Sentence denotes On the contrary, human Hyal-1 converted the HA octasaccharide mainly by hydrolysis with transglycosylation products occurring only at high substrate concentrations (> or = 500 microM).
T10 1446-1551 Sentence denotes The differences between the hyaluronidase subtypes and isoenzymes were much more prominent than expected.
T11 1552-1695 Sentence denotes Obviously, the different hyaluronidase subtypes have evolved into very specialized enzymes with respect to their catalytic mechanism of action.
T1 0-126 Sentence denotes Kinetics of Hyal-1 and PH-20 hyaluronidases: comparison of minimal substrates and analysis of the transglycosylation reaction.
T2 127-322 Sentence denotes The availability of recombinant expression systems for the production of purified human hyaluronidases PH-20 and Hyal-1 facilitated the first detailed analysis of the enzymatic reaction products.
T3 323-588 Sentence denotes The human recombinant enzymes, both expressed by Drosophila Schneider-2 (DS-2) cells, were compared to bovine testicular hyaluronidase (BTH), a commercially available hyaluronidase preparation, which has long been considered a prototype of mammalian hyaluronidases.
T4 589-721 Sentence denotes The conversion of low molecular weight hyaluronic acid (HA) fragments was detected by a capillary zone electrophoresis (CZE) method.
T5 722-881 Sentence denotes Surprisingly, the HA hexasaccharide, which is generally accepted to be the minimum substrate of BTH, was not a substrate of recombinant human PH-20 and Hyal-1.
T6 882-1019 Sentence denotes However, HA octasaccharide was converted efficiently by both enzymes, thus representing the minimum substrate for human PH-20 and Hyal-1.
T7 1020-1161 Sentence denotes Additionally, BTH was shown to catabolize the HA hexasaccharide at pH 4.0 mainly by hydrolysis, while at pH 6.0 transglycosylation prevailed.
T8 1162-1260 Sentence denotes Human PH-20 was found to catalyze both hydrolysis and transglycosylation of the HA octasaccharide.
T9 1261-1445 Sentence denotes On the contrary, human Hyal-1 converted the HA octasaccharide mainly by hydrolysis with transglycosylation products occurring only at high substrate concentrations (> or = 500 microM).
T10 1446-1551 Sentence denotes The differences between the hyaluronidase subtypes and isoenzymes were much more prominent than expected.
T11 1552-1695 Sentence denotes Obviously, the different hyaluronidase subtypes have evolved into very specialized enzymes with respect to their catalytic mechanism of action.

uniprot-human

Id Subject Object Predicate Lexical cue
T1 12-18 http://www.uniprot.org/uniprot/Q8NFK8 denotes Hyal-1
T2 240-246 http://www.uniprot.org/uniprot/Q8NFK8 denotes Hyal-1
T3 874-880 http://www.uniprot.org/uniprot/Q8NFK8 denotes Hyal-1
T4 1012-1018 http://www.uniprot.org/uniprot/Q8NFK8 denotes Hyal-1
T5 1284-1290 http://www.uniprot.org/uniprot/Q8NFK8 denotes Hyal-1
T6 23-25 http://www.uniprot.org/uniprot/P01298 denotes PH
T7 230-232 http://www.uniprot.org/uniprot/P01298 denotes PH
T8 864-866 http://www.uniprot.org/uniprot/P01298 denotes PH
T9 1002-1004 http://www.uniprot.org/uniprot/P01298 denotes PH
T10 1168-1170 http://www.uniprot.org/uniprot/P01298 denotes PH
T11 23-43 http://www.uniprot.org/uniprot/P38567 denotes PH-20 hyaluronidases
T12 215-235 http://www.uniprot.org/uniprot/P38567 denotes hyaluronidases PH-20
T13 396-398 http://www.uniprot.org/uniprot/P49366 denotes DS
T14 645-647 http://www.uniprot.org/uniprot/P69208 denotes HA
T15 740-742 http://www.uniprot.org/uniprot/P69208 denotes HA
T16 891-893 http://www.uniprot.org/uniprot/P69208 denotes HA
T17 1066-1068 http://www.uniprot.org/uniprot/P69208 denotes HA
T18 1242-1244 http://www.uniprot.org/uniprot/P69208 denotes HA
T19 1305-1307 http://www.uniprot.org/uniprot/P69208 denotes HA

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 12-18 http://www.uniprot.org/uniprot/Q91ZJ9 denotes Hyal-1
T2 240-246 http://www.uniprot.org/uniprot/Q91ZJ9 denotes Hyal-1
T3 874-880 http://www.uniprot.org/uniprot/Q91ZJ9 denotes Hyal-1
T4 1012-1018 http://www.uniprot.org/uniprot/Q91ZJ9 denotes Hyal-1
T5 1284-1290 http://www.uniprot.org/uniprot/Q91ZJ9 denotes Hyal-1
T6 23-25 http://www.uniprot.org/uniprot/P10601 denotes PH
T7 230-232 http://www.uniprot.org/uniprot/P10601 denotes PH
T8 864-866 http://www.uniprot.org/uniprot/P10601 denotes PH
T9 1002-1004 http://www.uniprot.org/uniprot/P10601 denotes PH
T10 1168-1170 http://www.uniprot.org/uniprot/P10601 denotes PH
T11 23-43 http://www.uniprot.org/uniprot/P48794 denotes PH-20 hyaluronidases
T12 215-235 http://www.uniprot.org/uniprot/P48794 denotes hyaluronidases PH-20

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 12-16 http://purl.bioontology.org/ontology/NCBITAXON/199485 denotes Hyal
T2 240-244 http://purl.bioontology.org/ontology/NCBITAXON/199485 denotes Hyal
T3 372-382 http://purl.bioontology.org/ontology/NCBITAXON/48321 denotes Drosophila
T4 372-382 http://purl.bioontology.org/ontology/NCBITAXON/186285 denotes Drosophila
T5 372-382 http://purl.bioontology.org/ontology/NCBITAXON/32281 denotes Drosophila
T6 372-382 http://purl.bioontology.org/ontology/NCBITAXON/7215 denotes Drosophila
T7 372-382 http://purl.bioontology.org/ontology/NCBITAXON/937257 denotes Drosophila
T8 372-382 http://purl.bioontology.org/ontology/NCBITAXON/30026 denotes Drosophila
T9 372-382 http://purl.bioontology.org/ontology/NCBITAXON/46879 denotes Drosophila
T10 372-382 http://purl.bioontology.org/ontology/NCBITAXON/43845 denotes Drosophila
T11 372-382 http://purl.bioontology.org/ontology/NCBITAXON/463113 denotes Drosophila
T12 372-382 http://purl.bioontology.org/ontology/NCBITAXON/1226646 denotes Drosophila
T13 372-382 http://purl.bioontology.org/ontology/NCBITAXON/937324 denotes Drosophila
T14 372-382 http://purl.bioontology.org/ontology/NCBITAXON/7214 denotes Drosophila
T15 372-382 http://purl.bioontology.org/ontology/NCBITAXON/348021 denotes Drosophila
T16 402-407 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T17 677-686 http://purl.bioontology.org/ontology/NCBITAXON/119095 denotes capillary
T18 677-686 http://purl.bioontology.org/ontology/NCBITAXON/241203 denotes capillary
T19 874-878 http://purl.bioontology.org/ontology/NCBITAXON/199485 denotes Hyal
T20 1012-1016 http://purl.bioontology.org/ontology/NCBITAXON/199485 denotes Hyal
T21 1284-1288 http://purl.bioontology.org/ontology/NCBITAXON/199485 denotes Hyal
T22 1675-1684 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes mechanism

GO-BP

Id Subject Object Predicate Lexical cue
T1 1051-1061 http://purl.obolibrary.org/obo/GO_0009056 denotes catabolize

GO-CC

Id Subject Object Predicate Lexical cue
T1 402-407 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 12-16 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
T2 240-244 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
T3 874-878 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
T4 1012-1016 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
T5 1284-1288 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
T6 677-686 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 12-16 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
PD-UBERON-AE-B_T2 240-244 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
PD-UBERON-AE-B_T3 874-878 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
PD-UBERON-AE-B_T4 1012-1016 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
PD-UBERON-AE-B_T5 1284-1288 http://purl.obolibrary.org/obo/UBERON_3000101 denotes Hyal
PD-UBERON-AE-B_T6 677-686 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 209-214 OrganismTaxon denotes human 9606
T2 327-332 OrganismTaxon denotes human 9606
T3 372-382 OrganismTaxon denotes Drosophila 2081351|32281|7215
T6 426-432 OrganismTaxon denotes bovine 9913
T7 858-863 OrganismTaxon denotes human 9606
T8 996-1001 OrganismTaxon denotes human 9606
T9 1162-1167 OrganismTaxon denotes Human 9606
T10 1278-1283 OrganismTaxon denotes human 9606
T11 1527-1536 OrganismTaxon denotes prominent 37571

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 677-686 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982